Clinical trials: DM
Type 2 Diabetes Mellitus (DM), Gastrointestinal Surgery
Preoperative Oral Carbohydrate Loading in Patients With Type 2 Diabetes Undergoing Gastrointestinal Surgery
This study is a single-center randomized controlled trial in adults with type 2 diabetes who are scheduled for elective gastrointestinal surgery.
- Trial name
- NCT07830537
- Testing
- Standard ERAS Fasting and Clear-Fluid Management, Oral Carbohydrate Loading, Intravenous Glucose
- Volunteers
- 126 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Type 2 Diabetes Mellitus
Study Comparing Efficacy and Safety of Amaryl M and Metformin Uptitraion to Type 2 DM
The aim of this study is to compare the efficacy and safety of early combination therapy with Amaryl M with that of uptitration of metformin monotherapy in patients with type 2 DM inadequately controlled by prior monotherapy with…
- Trial name
- NCT00612144
- Testing
- Glimepiride/metformin fixed combination, Metformin HCl
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Handok Inc.
Non-Alcoholic Fatty Liver Disease, Diabetes Mellitus
Iron Depletion Therapy for Type 2 DM and NAFLD
The purpose of this study is to find out whether lowering the amount of iron in the body will result in less resistance to insulin and improved liver function in patients with type 2 diabetes mellitus and non-alcoholic fatty…
- Trial name
- NCT00230087
- Testing
- blood donation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes (DM), Diabetes Mellitus Type 2
Bridge Study to Evaluate the Efficacy and Safety of IN-B00009 Injection in Patients With T2DM Inadequately Controlled by Diet and Exercise Alone
This Phase 3 Bridge study is designed to evaluate the efficacy and safety of IN-B00009 Injection in Patients with T2DM Inadequately Controlled by Diet and Exercise Alone
- Trial name
- NCT07308184
- Testing
- IN-B00009
- Volunteers
- 110 people
- Sponsor
- HK inno.N Corporation
Diabetes Mellitus
Effects of Acarbose Versus Glibenclamide on MAGE and Oxidative Stress in Patients With Type 2 DM
To compare effect of acarbose versus glibenclamide treatment on mean amplitude of glyclemic excursion and oxidative stress in diabetes individuals who failed to control their glucose by metformin therapy alone
- Trial name
- NCT00417729
- Testing
- Acarbose
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Taichung Veterans General Hospital
Kidney Transplant, Diabetes Mellitus, Type 2
Immunosuppression Impact on the Metabolic Control of Kidney Transplant With Pre-Existing Type 2 Diabetes (DM)
Protocol Title: Randomized open label study comparing the metabolic control of first Kidney Transplant recipients with Type 2 Diabetes Mellitus (DM) receiving either Prograf or Neoral as part of a ATG induction, prednisone free…
- Conditions
- Kidney Transplant, Diabetes Mellitus, Type 2, Diabetic Nephropathy
- Trial name
- NCT00296296
- Testing
- Cyclosporin, Tacrolimus, 'Diabetes Education / Management'
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Stanford University
Chronic Kidney Disease(CKD), Type 2 DM
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.
- Conditions
- Chronic Kidney Disease(CKD), Type 2 DM, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- IRIS-CKD (NCT06906627)
- Testing
- (IRIS-CKD Screening Program): Home Kit, (IRIS-CKD Screening Program): Standard Lab Order
- Where
- 7 sites in United States
- Volunteers
- 500 people
- Sponsor
- Duke University
Non-communicable Diseases (NCDs)
Community-Based Chronic Disease Care in Rural Lesotho
This ComBaCaL cohort study is to assess the impact of community-based, lay-led chronic disease screening and care interventions in rural Lesotho.
- Trial name
- ComBaCaL (NCT05596773)
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- 17,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Type 2 DM
Telehealth-Based Chronic Disease Management for Type 2 Diabetes
This study will be conducted from enrollment until the end of the six-month follow-up period. This study aims to assess the impact of the Internet hospital online + offline integrated chronic disease management model on patients…
- Trial name
- T2DMTH (NCT06719050)
- Volunteers
- 1,636 people
- Sponsor
- Zeng Lin, Ph. D.
Diabetes Mellitus
Glitazones and Endothelial Function (GATE)
The purpose of the study is to determine if the addition of rosiglitazone to subjects with fair glucose control on other oral agents improves endothelial function, a surrogate marker of vascular health.
- Trial name
- NCT00203632
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Diabetes Mellitus, Type 2
MANAGe-DM: Novel Nurse Case Management to Improve Diabetes Outcomes in Formerly Incarcerated Black Men
The study is a randomized control trial involving 100 participants (formerly incarcerated Black men with poorly controlled diabetes) to examine the effect of a tailored nurse case manager on glycemic control and other clinical…
- Trial name
- MANAGe-DM (NCT06031428)
- Testing
- MANAGe-DM - novel nurse case management, Monthly Educational Mailing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medical College of Wisconsin
Pseudoexfoliation
Corneal Endothelium Evaluation After Phacoemulsification in Diabetec and Non-diabetic Patients With Pseudoexfoliation
Our study is a comparative study, that was conducted to evaluate the corneal endothelial cells changes and central corneal thickness after uncomplicated phacoemulsification and intra ocular lens (IOL) implantation in normal…
- Trial name
- NCT04965168
- Testing
- phacoemulsification of the lens
- Where
- Egypt
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Minia University
Diabetes Mellitus, Dyslipidemia
Prevalence of Subclinical Atherosclerosis and Its Associated Factors in Hyperlipidemic Korean Adults With Diabetes
This study is to investigate correlation between Carotid Intima Media Thickness (cIMT) and several factors such as; hs C-reactive protein (CRP), HbA1c, lipid profile in Korean diabetic patients with atherosclerosis.
- Trial name
- ALTO (NCT01264263)
- Where
- 3 sites in South Korea
- Volunteers
- 181 people
- Sponsor
- AstraZeneca
Diabetes-Related Complications, Diabetes Mellitus, Type 2
Effect of Diacerein in the Metabolic Control of Patients With DM Type 2 and Secondary Failure to Metformin
Considering that, Diacerein is on the market for almost 20 years, being used continuously in elderly patients with osteoarthritis without present significant side effects, and considering the anti-hyperglycemic effect and the…
- Conditions
- Diabetes-Related Complications, Diabetes Mellitus, Type 2, Insulin Resistance
- Trial name
- NCT02177643
- Testing
- Diacerein
- Where
- 3 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- University of Campinas, Brazil
Dermatomyositis
Severity Factors of Dermatomyositis in the Caribbean Population - DM-ANTILLES
Dermatomyositis is a rare chronic autoimmune and inflammatory disease that affects the skin and striated muscles. Its prognosis is linked to visceral involvement (lungs, heart, and oropharyngeal region) and to the possible…
- Trial name
- DM-ANTILLES (NCT07265999)
- Where
- Guadeloupe
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Dermatomyositis
Study of NM8074 in Patients with Dermatomyositis (DM)
This is a Phase II, open-label, multicenter study to evaluate the safety and efficacy of NM8074 administered via intravenous infusion in patients with Dermatomyositis (DM).
- Trial name
- NCT06887738
- Testing
- NM8074
- Volunteers
- 8 people
- Sponsor
- NovelMed Therapeutics
Type2 Diabetes Mellitus
SGLT-2 Inhibitor and Myocardial Perfusion, Function and Metabolism in T2 DM Patients at High Cardiovascular Risk
Patients with type 2 diabetes (T2 DM) have a markedly increased risk of heart disease and it is estimated that, in the danish population, up 80% percent of patients with type 2 diabetes die from heart disease.
- Trial name
- SIMPLE (NCT03151343)
- Testing
- Empagliflozin
- Where
- Denmark
- Volunteers
- 92 people
- Sponsor
- Caroline M Kistorp
Type 1 Diabetes
Hypoglycemia Associated Autonomic Failure in Type 1 DM, Q2
Alprazolam (Xanax) will blunt the body's ability to defend itself from low blood sugar.
- Trial name
- NCT00592332
- Testing
- Alprazolam, control group
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Metabolic Syndrome
Relation Between Serum Uric Acid and Metabolic Syndrome in Type 2 DM
This study will be undertaken to evaluate the association of serum uric acid (SUA) level with metabolic risk factors in patients with type 2 diabetes and their relation to eGFR status
- Trial name
- NCT04575389
- Testing
- Serum uric acid levels ,HBA1C , fasting plasma glucose ,lipid profile , creatinine level
- Volunteers
- 100 people
- Sponsor
- Assiut University
Type 2 Diabetes, Mental Health
Technology-Enabled Collaborative Care for Diabetes and Mental Health
Managing both type 2 diabetes and mental health challenges can be difficult, and many people do not receive care that supports both.
- Conditions
- Type 2 Diabetes, Mental Health, Diabetes Distress
- Trial name
- TECC-DM (NCT07181863)
- Testing
- Health coaching, Educational emails
- Where
- 2 sites in Canada
- Volunteers
- 160 people
- Sponsor
- McMaster University