Clinical trials: DM
Diabetes (DM), Periodontitis
Relationship Between Diabetes and Periodontitis
Diabetes mellitus, one of the major global health problems of the 21st century, is a chronic metabolic disease characterized by dysregulated nutrient metabolism resulting from defects in insulin secretion and action.
- Trial name
- NCT07193979
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Type 1 Diabetes
Hypoglycemia Associated Autonomic Failure in Type 1 DM
It is unclear what effect selective serotonin reuptake inhibitors (SSRIs) have on hypoglycemia. Thus, the American Hospital Formulary Service recommends careful monitoring of blood glucose levels in all patients with diabetes…
- Trial name
- NCT00592670
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Subjects With Mild Hypertriglyceridemia in Type 2 DM
Consumption of Whole Grains and Legumes Modulates the Genetic Effect of the APOA5 -1131C Variant
We examined whether a substitution of whole grains and legumes for refined rice in a high carbohydrate diet (about 65% of energy derived from carbohydrate) may modify the effect of this variant on changes in apolipoprotein A-V…
- Trial name
- NCT01784952
- Testing
- Dietary intervention
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Diabetes Mellitus, Type 1, Diabetes
The T1D Exchange Registry
The T1D Exchange Registry is a research study, conducted over time, for individuals with type 1 diabetes and their supporters. Participants volunteer to provide their data for research (for example, by answering questions in…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes, Type 1 Diabetes, Diabetes Mellitus
- Trial name
- T1D Registry (NCT04629586)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- T1D Exchange, United States
Type 2 Diabetes
Relationship Between Insulin Resistance and Vitamin D in Type 2 Diabetes Mellitus (DM)
The primary aim of the study is to evaluate the association between vitamin D levels and triglyceride-glucose index as a marker of insulin resistance in patients with type 2 DM.
- Trial name
- DM (NCT07467161)
- Volunteers
- 165 people
- Sponsor
- Assiut University
Type 2 Diabetes Mellitus, Liver Dysfunction
Pharmacokinetic and Pharmacodynamic Study of Glufast Tablets 10mg(Mitiglinide)
This clinical trial is designed to assess the effect of hepatic impairment on the pharmacokinetic and pharmacodynamic of glufast tablets 10 mg.
- Trial name
- NCT04349696
- Testing
- Mitiglinide
- Where
- 2 sites in Taiwan
- Volunteers
- 16 people
- Sponsor
- Orient Europharma Co., Ltd.
Type 2 Diabetes
Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Pilot Study)
Type 2 diabetes mellitus is a chronic metabolic disorder characterized by progressive deterioration in the function of the pancreatic beta-cells, which are the cells that produce and secrete insulin (the hormone primarily…
- Trial name
- NCT01755468
- Testing
- Intermittent insulin therapy, Continuous metformin
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Mount Sinai Hospital, Canada
Diabetes
Comprehensive Intervention to Evaluate Outcomes AND Cost in Hospitalized Surgical Patients With Diabetes Mellitus (DM)
This study is being performed to evaluate whether a comprehensive discharge planning and close follow up for one year can improve clinical outcomes and cut costs of care for patients with poorly controlled diabetes.
- Trial name
- COACH-DM (NCT02065050)
- Testing
- team-based care
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Brigham and Women's Hospital
Type 2 Diabetes Mellitus
Tissue Distribution of F18-FDG Labelled Autologous Bone Marrow Derived Stem Cells in Patients With Type 2 DM
Investigators purpose is to track stem cells in vivo in the type 2 diabetes mellitus patients after the same have been labelled with positron emission tomography tracer F18-FDG; as it is assumed that the therapeutic outcome will…
- Trial name
- NCT01694173
- Testing
- Stem cell therapy- SPD artery, Stem cell therapy- splenic artery, Stem cell therapy-intravenous
- Where
- India
- Volunteers
- 28 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Elderly Patients (>65 Years), Diabetes (DM)
Multidisciplinary Dissection of Renal and Metabolic Effects of Glyfozines on Elderly Patients: From Molecular Aspects to Clinical Indications
The project aims to study the impact of SGLT2i therapy on clinical and biochemical aspects. in elderly. The project will combine different types of data, such as clinical and biological information, and will use advanced Bayesian…
- Conditions
- Elderly Patients (>65 Years), Diabetes (DM), Heart Disease, Renal Diseases
- Trial name
- NCT07119424
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Chiara Lanzani
Type 2 Diabetes, Heart Failure
Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials.
- Trial name
- NCT07390110
- Testing
- Oral semaglutide, Sitagliptin
- Where
- United States
- Volunteers
- 25,664 people
- Sponsor
- Brigham and Women's Hospital
Advanced Cancer
DM-CHOC-PEN Plus Radiation for Brain Tumors
4-Demethyl-4-cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) is a polychlorinated pyridyl cholesterol carbonate that is lipophilic, electrically neural, crosses the blood brain barrier (BBB), ability to localize in intracranial…
- Trial name
- NCT03371004
- Testing
- 4-Demethyl-4-cholesteryloxycarbonylpenclomedine
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- DEKK-TEC, Inc.
Androgen Deficiency, AD
Hormones and Sexual Function Predict Outcomes in Revascularized Men With Diabetes
The purpose of this study is to find out if androgen deficiency (low levels of testosterone, a male hormone produced by the sex glands) and erectile dysfunction (sexual dysfunction) will predict over time the development of a…
- Conditions
- Androgen Deficiency, AD, Erectile Dysfunction, ED
- Trial name
- HEART-MEND (NCT01190904)
- Where
- 5 sites in United States
- Volunteers
- 568 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Diabetes Mellitus
COMPARISON BETWEEN TWO SUB-TYPES OF HIGH INTENSITY INTERVAL TRAINING
Recently, HIIT has been recommended by the American diabetes association for type 2 diabetes. The high-volume HIIT has been studied extensively in patients with type 2 diabetes, however, little is known about the effectiveness of…
- Trial name
- NCT05110404
- Testing
- The high-volume HIIT, The low-volume HIIT
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Peri Implant Mucositis, Peri Implant Bone Loss
Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
Introduction: Dental implants offer a durable, aesthetic, and functional option for tooth replacement. However, they are not immune to failure.
- Conditions
- Peri Implant Mucositis, Peri Implant Bone Loss, Peri Implantitis, Calcium Deficiency
- Trial name
- NCT07766707
- Where
- Spain
- Volunteers
- 192 people
- Sponsor
- University of Barcelona
Gestational Diabetes Mellitus in Pregnancy
Lifestyle Intervention IN Gestational Diabetes (LIVING)
Investigators have taken the learning from various programs to develop a new lifestyle program (LIVING) that has a high probability of being feasible, acceptable and cost-effective in the South Asian context for women with prior…
- Trial name
- LIVING (NCT03305939)
- Testing
- Life style Intervention
- Where
- 20 sites in Bangladesh, India and 1 more
- Volunteers
- 1,612 people, healthy volunteers welcome
- Sponsor
- The George Institute
Hip Osteoarthritis
Continuation of Patient Follow-up to 2 Years for the Pinnacle RSA and Pinnacle DM RSA Clinical Trials
The proposed study is a continuation of two prospective, multi-centre, non-controlled studies of the Pinnacle and Pinnacle Dual Mobility total hip arthroplasty systems, originally initiated by DePuy Synthes (DSJ_2018_02 and…
- Trial name
- NCT05930067
- Testing
- Pinnacle Gription Acetabular Cup, Pinnacle Dual Mobility
- Where
- 2 sites in Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Type 2 Diabetes, Impaired Glucose Intolerance
G-CREDIT (Gangnam-Cohort for Risk Evaluation of Diabetes and Impaired Glucose Tolerance)
The prevalence of type 2 diabetes has consistently increased and type 2 diabetes can cause many types of vascular complications. Diabetes develops due to glucose intolerance.
- Trial name
- NCT02726256
- Volunteers
- 500 people
- Sponsor
- Yonsei University
Type 2 DM
Carbohydrate Quality and Its Impact on Sleep and Depression in Type 2 Diabetes
The aim of this study was to evaluate the effect of carbohydrate quality on sleep quality and depression in patients with Type 2 diabetes.
- Trial name
- NCT06666205
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ankara Yildirim Beyazıt University
Non Insulin Dependent Diabetes Mellitus
Prospective Observatonal Study for Effect of Duodenojejunal Bypass and Gastric Bypass on T2DM Patients
Surgical treatment for type 2 diabetes has been taken note especially in less obese or non obese patients. In Asian, the nuber of less obses or non obese patients with T2DM is greater than that of the obese.
- Trial name
- T2DM (NCT01735253)
- Testing
- laparoscopic roux en Y gastric bypass / open duodenojejunal bypass
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Inha University Hospital