Clinical trials: DM
Diabetes Mellitus (DM)
Post ACA Reform: Evaluation of Community Health Center Care of Diabetes
This innovative and timely study will measure the impact of Affordable Care Act (ACA) Medicaid expansions on diabetes mellitus (DM) prevention, treatment, expenditures and health outcomes.
- Trial name
- PREVENTD (NCT02685384)
- Testing
- Medicaid Expansion
- Volunteers
- 1,938,375 people
- Sponsor
- Oregon Health and Science University
Obesity, DM
Lap-Band Surgery on Adolescents for Safety and Efficacy
This study is to demonstrate the safety and efficacy of the use of the LAP-BAND surgery in the morbidly obese adolescent population.
- Trial name
- ALAGB (NCT00587301)
- Testing
- Lap-Band
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- NYU Langone Health
Patients With Type 2 DM Who Underwent Coronary Angiography Due to Coronary Artery Disease and Presence of Microvascular Complications in Same Patients
Correlation Between Micro Vascular Complications and Severity of Coronary Artery Disease in Type 2 DM
Diabetes is a major cause of morbidity and mortality worldwide and it contributes substantially to healthcare costs. Type 2 Diabetes mellitus is the most common type of diabetes accounting for approximately (90%) of all cases.
- Trial name
- NCT04975828
- Testing
- albumin creatinine ratio -EGFR-fundus examination- coronary angiography.
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sohag University
Vitamin k2 in Type 2 DM
Relation Between Plasma Vitamin K2 and Glycemic Control and Metabolic Parameters in Type 2 Diabetic Patients.
Background and Rationale: The agents inducing type 2 diabetes are yet to be clarified. Current studies show that several genetic and environmental parameters are associated with type 2 diabetes .
- Trial name
- NCT04387019
- Testing
- blood sampling
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peripheral Arterial Disease (PAD), Diabetes Mellitus (DM)
The Efficacy and Safety of REX-001 to Treat Ischemic Rest Pain in Subjects With CLI Rutherford Category 4 and DM
This trial is a pivotal, placebo-controlled, double-blind, parallel-group, adaptive trial conducted in subjects with DM and CLI Rutherford Category 4.
- Conditions
- Peripheral Arterial Disease (PAD), Diabetes Mellitus (DM), Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT03111238
- Testing
- REX-001
- Where
- 15 sites in Czechia, Germany and 4 more
- Volunteers
- 3 people
- Sponsor
- Ixaka Ltd
Non-DM Stage II High-risk Colorectal Cancer, Non-DM Stage III Colorectal Cancer
Effect of Adjunctive Metformin on Recurrence of Non-DM Colorectal Cancer Stage II High-risk/ III Colorectal Cancer
The aim of this study is to identify the effect of adjunctive metformin on recurrence of non-DM Stage II High-risk/ III colorectal cancer. This study is open-label randomized controlled study.
- Trial name
- NCT02614339
- Testing
- metformin, control
- Where
- South Korea
- Volunteers
- 593 people
- Sponsor
- Yonsei University
dm
Clinical Study Evaluating Vildagliptin Versus Vildagliptin/Metformin on NAFLD With DM
Clinical study evaluating vildagliptin versus vildagliptin/metformin on NAFLD with DM.
- Trial name
- NCT03925701
- Testing
- Vildagliptin, vildagliptin\metformin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Sherief Abd-Elsalam
DM
Impact of P53 and SIRT1 in Type 2 Diabetes
Investigating the impact of p53 and SIRT1 in the development of type 2 DM
- Trial name
- NCT03925714
- Testing
- life style, Metformin, Nigetella salivata
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sherief Abd-Elsalam
Diabetes Mellitus (DM), Congestive Heart Failure (CHF)
Expanding Paramedicine in the Community
Initiatives aimed at reducing Emergency Department (ED) wait times and improved community health initiatives are major priorities in Canada.
- Conditions
- Diabetes Mellitus (DM), Congestive Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- EPIC (NCT02034045)
- Testing
- Community Paramedicine, Usual Care
- Where
- 4 sites in Canada
- Volunteers
- 467 people
- Sponsor
- Unity Health Toronto
Dermatomyositis Interstitial Lung Disease (Dm-ILD)
Efficacy and Safety of Pirfenidone in Patient With Dermatomyositis Interstitial Lung Disease (Dm-ILD)
The purpose of this study is to evaluate the efficacy and safety of pirfenidone in subjects with dermatomyositis interstitial lung disease
- Trial name
- NCT03857854
- Testing
- Pirfenidone
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Beijing Continent Pharmaceutical Co, Ltd.
Diabetes Mellitus (DM)
Comparison on Efficacy and Safety of Three Inpatient Insulin Therapy in Type2 DM
Purpose: To compare efficacy and safety of traditional sliding scale insulin (SSI) versus modified 70/30 insulin versus modified basal plus supplemental scale /bolus insulin regimens for glycemic control in hospitalized diabetic…
- Trial name
- NCT01855243
- Testing
- regular insulin, 70/30 insulin, Glargine
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Cairo University
Type 2 DM Patients With Moderate or Severe Renal Impairment
A Phase IIIb Study to Evaluate the Safety and Efficacy of Gemigliptin in Type 2 Diabetes Mellitus Patients With Moderate or Severe Renal Impairment(GUARD Study)
Therapuetic options are limited for Type 2 Diabetes Mellitus (T2DM) pateints with renal impairment. This clinical study is to asses safety and efficacy of the DPP-4 inhibitor gemigliptin in patients with type 2 DM and moderate or…
- Trial name
- GUARD (NCT01968044)
- Testing
- Gemigliptin
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- LG Life Sciences
Type 2 Diabetes Mellitus, DM Nephropathy
Effects of Disease Management on Development of End Stage Renal Disease in Type 2 Diabetic Patients With Nephropathy
Disease management using a multidisciplinary team to achieve and maintain optimal metabolic and cardiovascular risk factors control in Type 2 diabetic patients with nephropathy reduces the incidence of end stage renal disease…
- Trial name
- NCT00309127
- Testing
- Multidisciplinary team care
- Where
- China
- Volunteers
- 205 people
- Sponsor
- Chinese University of Hong Kong
Dementia, DM
Early Detection of Cognitive Dysfunction in Diabetes
The rate of cognitive decline due to ageing is increased 1.5-fold to 2.0-fold in individuals with type 2 diabetes.There are no established specific treatment measures to prevent or ameliorate cognitive impairments in patients…
- Conditions
- Dementia, DM, MCI
- Trial name
- NCT01830998
- Where
- 3 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Wuhan General Hospital of Guangzhou Military Command
Subjects With Mild Hypertriglyceridemia in Type 2 DM
Consumption of Whole Grains and Legumes Modulates the Genetic Effect of the APOA5 -1131C Variant
We examined whether a substitution of whole grains and legumes for refined rice in a high carbohydrate diet (about 65% of energy derived from carbohydrate) may modify the effect of this variant on changes in apolipoprotein A-V…
- Trial name
- NCT01784952
- Testing
- Dietary intervention
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Rheumatoid Arthritis, Spondyloarthritis
Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases
The prognosis of rheumatic diseases has improved considerably with development of therapy. However, infections are considered the most important cause of morbidity and mortality in this group of patients.
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Systemic Lupus Erythematosus (SLE), Dermatomyositis (DM)
- Trial name
- NCT01151644
- Testing
- Anti-pandemic H1N1 influenza vaccine
- Where
- Brazil
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Impaired Glucose Tolerance, Peripheral Polyneuropathy
Electrodiagnostic Parameters in Patients With Impaired Glucose Tolerance and Diabetes Mellitus
The purpose of this study is to evaluate the distal sensory nerves of the feet, namely, the dorsal sural, medial dorsal cutaneous and medial plantar nerves, in patients with impaired glucose tolerance and diabetes mellitus type 2…
- Conditions
- Impaired Glucose Tolerance, Peripheral Polyneuropathy, DM
- Trial name
- NCT01094418
- Testing
- Nerve conduction studies ( NCS) of the peripheral nerves
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea