Clinical trials: DNA Sequencing
Healthy Adults
A Study to Understand How the Body Processes [14C]PF-07104091 in Healthy Participants
The purpose of this study is to learn how the body processes the study medicine PF-07104091. The study is seeking participants who are: Healthy male aged 18 to 65 years of age Participants in the study will receive 14C-labeled…
- Trial name
- NCT07127770
- Testing
- PF-07104091
- Where
- Netherlands
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
Drug Drug Interaction Study With Lu AG06466 in Young Healthy Men
The purpose of this study is to evaluate the effect of repeated doses of the drug Lu AG06466 on the exposure of metoprolol, midazolam and bupropion
- Trial name
- NCT04713254
- Testing
- Lu AG06466, Midazolam, Metoprolol
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy
Safety and Tolerability Comparison of Immediate and Controlled Release Formulations of Ecopipam
Ecopipam hydrochloride (HCl) is an investigational drug being studied for several possible diseases. To date, all clinical studies have been done using the ecopipam immediate release (IR) tablet.
- Trial name
- NCT01408394
- Testing
- Ecopipam immediate release form, 90 mg controlled release form, 180 mg controlled release form
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Emalex Biosciences Inc.
Stable Angina
A Study To Evaluate The Effect of T89(Dantonic®)On P450 Enzymes
Purpose: This study is to determine the effect of T89(Dantonic®)on P450 enzymes. This study will help determine which types of drugs may interact with T89.
- Trial name
- NCT01473888
- Testing
- T89(Dantonic)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tasly Pharmaceuticals, Inc.
Rapid Sequence Intubation
Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
This study examines the performance of a nasal cannula end-tidal oxygen (EtO2) measurement as compared to the gold standard of single breath end-tidal oxygen measurements in healthy volunteers.
- Trial name
- NCT03840486
- Testing
- Non-rebreather mask (NRBM), Non-invasive ventilator mask (NIV), Nasal cannula EtO2 sensor
- Where
- 2 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Emory University
Healthy
Bioequivalence Study of Ibandronate Sodium Tablets 150 mg Under Fasting Condition
This is an open label, randomised, balanced, two-treatment, two-period, two-sequence, crossover, oral bioequivalence study.
- Trial name
- NCT01627886
- Testing
- Ibandronate sodium
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy Adult Males Volunteers
A Comparative Bioavalability Study of Tamsulosin 0.4 mg Prolonged-release Tablets Versus the Reference Drug Omnic Ocas®, Tabsulosine 0.4 mg Tablets in Healthy Adult Male Subjects, at Steady State
The aim of this study is to evaluate the bioequivalence and safety of Tamsulosin hydrochloride 0.4 mg, prolonged-release tablets (Synthon Hispania SL, Spain), compared to Omnic Ocas®, Tamsulosin hydrochloride 0,4 mg…
- Trial name
- NCT07146711
- Testing
- Tamsulosin (0.4 mg/j), Omnic Ocas®,
- Where
- Armenia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Berlin-Chemie AG Menarini Group
Healthy Subjects
A Pharmacokinetic Study to Assess Drug-drug Interaction Between Zanubrutinib and a Cocktail of Substrates in Healthy Subjects
This study is designed to evaluate the safety and pharmacokinetic interaction of effects of multiple doses of zanubrutinib with a "Cocktail" of five probe drugs for cytochrome P450 (CYP) 3A, CYP2C9, CYP2C19, P-glycoprotein and…
- Trial name
- NCT03561298
- Testing
- BGB-3111 and Drug Cocktail
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- BeiGene
Pain
A Bioequivalence Study of Advil PM Liqui-Gels Minis (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) Compared to the Current Marketed Advil PM Liqui-Gels (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) in Healthy Adult Subjects Under Fasted Conditions
The purpose of this study is to support the submission of Advil PM Liqui-Gels Minis (ibuprofen/diphenhydramine hydrochloride 200 milligrams [mg]/25 mg) which is a size reduction of the currently marketed Advil PM Liqui-Gels, by…
- Trial name
- NCT05674721
- Testing
- Advil PM Liqui-Gels Minis, Advil PM Liqui-Gels
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- HALEON
Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated
MRI Sequence and Imaging Protocol Development
The purpose of this study is to develop imaging protocols when using cardiovascular magnetic resonance (CMR) to assess cardiac functions, morphology and tissue characterization.
- Conditions
- Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated, Left Ventricular Hypertrophy, Ischemic Heart Disease
- Trial name
- BikeMRI (NCT03040947)
- Testing
- Cardiovascular Magnetic Resonance
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Healthy
Bioequivalence Study of Minocycline HCl 135 mg ER Tablet Sunder Fed Conditions
The study was conducted as an open-label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover, bioequivalence study comparing Minocycline hydrochloride extended release tablets 135 mg…
- Trial name
- NCT02312609
- Testing
- Minocycline hydrochloride
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Healthy
A Study to Assess the Effects of Multiple-Dose Probenecid on the Multiple-Dose Pharmacokinetics of Canagliflozin in Healthy Volunteers
The purpose of this study is to assess the effects of multiple doses of probenecid on the multiple-dose pharmacokinetics of canagliflozin and its metabolites in healthy volunteers. Safety and tolerability will also be assessed.
- Trial name
- NCT01428284
- Testing
- Canagliflozin/Probenecid
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Bioequivalence Study in Healthy Subjects
Bioequivalence Assessment Between Two Perampanel Oral Suspension Formulations
An open label, randomized, single-dose, two-sequences, two-periods, crossover study to assess the bioequivalence of perampanel in Lepsiramp 0.5mg/ml oral suspension (Test product) in comparison with Fycompa® 0.5mg/ml oral…
- Trial name
- NCT06969963
- Testing
- Lepsiramp, 0.5 Mg/mL Oral Suspension, Fycompa, 0.5 Mg/mL Oral Suspension
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aya Mohammed Abdel Magid Abdel Hamid
Healthy
Semi-replicate Crossover Bioequivalence Study of Dirithromycin of (Abdi İbrahim İlaç San. Ve Tic. A. Ş., Turkey) in Healthy Subjects Under Fasting Conditions
The purpose of this study is to assess the bioequivalence of the investigational TEST product with the marketed REFERENCE products by measurement of Plasma concentrations of Erythromycylamine and calculation of the bioequivalence…
- Trial name
- NCT02237768
- Testing
- DIRITHROMYCIN 500 MG ENTERIC COATED TABLET, DYNABAC 250 MG ENTERIC COATED TABLET
- Where
- Jordan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pharmaceutical Research Unit, Jordan
Pharmacokinetics of Mirabegron, Healthy Subjects
To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol
The study aims to compare blood and urine concentrations of mirabegron (YM178) in healthy poor or extensive metabolizers for CYP2D6 and to evaluate if blood levels of metoprolol change whilst being dosed at the same time with…
- Trial name
- NCT01478490
- Testing
- mirabegron, metoprolol
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Type 2 Diabetes Mellitus
A Study To Estimate The Effect Of Repeated Dosing of PF-05175157 On The Pharmacokinetics Of A Single Dose Of Simvastatin In Healthy Adult Subjects
The study is designed to investigate the effect of repeated dosing of PF-05175157 on the pharmacokinetics of a single dose of Simvastatin in healthy adult subjects.
- Trial name
- NCT01469468
- Testing
- Simvastatin, PF-05175157
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
A Study in Healthy Men to Test Whether BI 1015550 Influences the Amount of Nintedanib and Pirfenidone in the Blood
The main objective of this trial is to investigate the induction effect of multiple oral doses of BI 1015550 on the pharmacokinetics of nintedanib or pirfenidone.
- Trial name
- NCT06070610
- Testing
- BI 1015550, Nintedanib, Pirfenidone
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Embolism and Thrombosis
A Study to Compare Pharmacokinetic Parameters and Safety Profiles Between AD-109 and AD-1091
Primary endpoint of this study is to evaluate the pharmacokinetic characteristics of AD-109 in healthy male subjects.
- Trial name
- NCT05128591
- Testing
- Rivaroxaban 18mg Oral Tablet, Rivaroxaban 20 MG Oral Tablet
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Healthy
Bioequivalence Study of Montelukast Sodium Chewable Tablets 4mg and 5mg Under Fed Condition
This is an open label, randomised, balanced, two-treatment, two-period, two-sequence, single dose, crossover, oral bioequivalence study.
- Trial name
- NCT01674517
- Testing
- Montelukast sodium chewable tablets 4mg and 5mg
- Where
- India
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Bioequivalence, Diabetes Mellitus, Type 2
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.
The objective of this study was to evaluate and compare the bioavailability and therefore to assess the bioequivalence of two different formulations of sitagliptin/metformin extended release tablets after a single oral dose…
- Trial name
- NCT06124547
- Testing
- Sitagliptin/Metformin HCl 50/500 mg extended release film-coated tablet
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Galenicum Health
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.