Clinical trials: DVT - Deep Vein Thrombosis
Vascular Access Complication, Central Line Complication
Novel Strategy to Encourage Early Removal of Central Venous Catheters
The goal of this study is to determine if early placement of a midline catheter in patients with a central venous catheter (CVC) will decrease the number of days the CVC is in place.
- Conditions
- Vascular Access Complication, Central Line Complication, Central Line-Associated Infection, Superficial Vein Thrombosis
- Trial name
- NCT04136561
- Testing
- Midline catheter
- Where
- United States
- Sponsor
- Corewell Health East
Deep Venous Thrombosis
Biomarker Sub Study of the Compression Stockings to Prevent the Post-Thrombotic Syndrome (SOX) Trial
The purpose of this study is to evaluate whether biomarkers of inflammation, genetic thrombophilia and coagulation activation influence Post-Thrombotic Syndrome development in patients with symptomatic proximal deep venous…
- Trial name
- Bio-SOX (NCT01615705)
- Where
- 25 sites in United States, Canada
- Volunteers
- 803 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Deep Vein Thrombosis, Pulmonary Embolism
Diagnosing Deep-vein Thrombosis Early in Critically Ill Patients
The DETECT randomized controlled trial addresses the question of whether surveillance ultrasound in critically ill patients by facilitating DVT detection reduces the incidence of PE and lowers all-cause 90-day mortality.
- Trial name
- DETECT (NCT05112705)
- Testing
- Proximal lower limb ultrasound
- Where
- Saudi Arabia
- Volunteers
- 1,800 people
- Sponsor
- King Abdullah International Medical Research Center
Anemia, Venous Thrombosis
A Study to Confirm the Safety and Efficacy of Epoetin Alfa (PROCRIT) Administered Perioperatively vs. the Standard of Care in Blood Conservation in Patients Undergoing Major Elective Spinal Surgery (SPINE Study)
This study is designed to investigate the incidence of deep vein thrombosis in patients receiving a perisurgical regimen of epoetin alfa (PROCRIT®) as compared to patients receiving standard of care blood conservation management.
- Trial name
- NCT00211146
- Testing
- epoetin alfa
- Volunteers
- 680 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Thrombosis, Deep Vein, Iliofemoral; Thrombosis
Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT
This is a study of a medical procedure that utilizes a commercially available catheter (the Bullfrog® Micro-Infusion Device) to locally deliver a commercially available anti-inflammatory drug (dexamethasone sodium phosphate…
- Trial name
- DEXTERITY-AFP (NCT04862468)
- Testing
- Perivascular dexamethasone
- Where
- 22 sites in United States, Ireland and 1 more
- Volunteers
- 80 people
- Sponsor
- Mercator MedSystems, Inc.
Catheter Thrombosis, Catheter-Related Infections
The Central Venous Catheter Related Complications in Critically Ill Patients
In this prospective clinical study, the researchers investigate the incidence of catheter-related thrombosis and catheter-related infection during indwelling central venous catheterization in critically ill patients, and analyzed…
- Conditions
- Catheter Thrombosis, Catheter-Related Infections, Central Venous Catheter Related Bloodstream Infection, Central Venous Catheter Thrombosis
- Trial name
- NCT03841240
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Zhujiang Hospital
Deep Vein Thrombosis, DVT
BOLT-DVT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis
The objective of this study is to demonstrate the safety and efficacy of the Indigo Aspiration system for percutaneous mechanical thrombectomy in a population presenting with obstruction due to deep vein thrombosis (DVT) who are…
- Trial name
- NCT05003843
- Testing
- Indigo Aspiration System
- Where
- 42 sites in United States
- Volunteers
- 229 people
- Sponsor
- Penumbra Inc.
Deep Vein Thrombosis, Pulmonary Embolus
Replication of the RECORD1 Anticoagulant Trial in Healthcare Claims Data
Investigators are building an empirical evidence base for real world data through large-scale replication of randomized controlled trials.
- Trial name
- NCT05083455
- Testing
- Rivaroxaban, Enoxaparin
- Where
- United States
- Volunteers
- 89,215 people
- Sponsor
- Brigham and Women's Hospital
Deep-Venous Thrombosis, Deep Venous Stenting
Stent Versus Conservative Treatment in Patients With Deep Venous Obstruction
Patients will be randomised between deep venous stenting or conservative management
- Conditions
- Deep-Venous Thrombosis, Deep Venous Stenting, Randomized Clinical Trial
- Trial name
- STEVECO (NCT03026049)
- Testing
- deep venous stenting
- Where
- Netherlands
- Volunteers
- 65 people
- Sponsor
- Maastricht University Medical Center
Atrial Fibrillation, Deep Vein Thrombosis
Pilot Study: Comparison of Patients' Knowledge of Direct Oral Anticoagulants in Post-hospitalization Between 2 Cardiology Departments Offering or Not a Pharmaceutical Interview During Hospitalization
Direct oral anticoagulants (Rivaroxaban, Apixaban and Dabigatran) are an alternative to anti-vitamin K drugs and low molecular weight heparins in many cardiovascular diseases.
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- EDUC-AOD (NCT04674202)
- Testing
- Phone interview
- Where
- 2 sites in France
- Volunteers
- 154 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Acute Leukemia, Deep Vein Thrombosis
Understanding the Risk of Blood Clots and Bleeding in Patients With Hematological Malignancies, HAT Study
This study evaluates the risks and experience of blood clots and bleeding in patients with blood cancers. While it is standard of care to use medications to reduce the risk of blood clots in hospitalized individuals, some…
- Conditions
- Acute Leukemia, Deep Vein Thrombosis, Hematopoietic and Lymphoid Cell Neoplasm, Hodgkin Lymphoma
- Trial name
- NCT05053100
- Testing
- Biospecimen Collection, Electronic Health Record Review
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Venous Thromboembolism
DULCIS (D-dimer and ULtrasonography in Combination Italian Study)
The purpose of this study is to evaluate the efficacy and safety of a standardized procedure to establish the optimal duration of anticoagulation in patients with venous thromboembolism.
- Trial name
- DULCIS (NCT00954395)
- Testing
- D-dimer
- Where
- Italy
- Volunteers
- 1,100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Deep Vein Thrombosis
Incidence of Deep Vein Thrombosis at Doppler Echo in Covid-19 Patients With SARS-Cov-2 Pneumopathy Hospitalized in ICU
The main objective of the study is to determine the incidence of deep vein thromboses at Doppler echo in patients with SARS-Cov-2 pneumopathy upon their entry into ICU and after 7 days of hospitalization in ICU.
- Trial name
- COVIDOP-DVT (NCT04363528)
- Testing
- Doppler Echo
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Versailles Hospital
Venous Thromboembolism
A Phase 3 Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Knee Arthroplasty
The objective of this study is to assess the efficacy and safety of DU-176b compared with enoxaparin sodium for the prevention of venous thromboembolism in patients after elective total knee arthroplasty.
- Trial name
- NCT01181102
- Testing
- edoxaban, enoxaparin sodium
- Where
- 3 sites in Japan, Taiwan
- Volunteers
- 716 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Suspected Upper Extremity Deep Vein Thrombosis
Diagnostic Algorithm in Suspected Upper Extremity Deep Vein Thrombosis
Deep vein thrombosis (DVT) of the arm, officially called upper extremity DVT is a rare disorder and accounts for up to 1-4% of all cases of deep vein thrombosis.
- Trial name
- Armour (NCT01324037)
- Testing
- diagnostic algorithm
- Where
- 18 sites in United States, Austria and 5 more
- Volunteers
- 406 people
- Sponsor
- University Medical Center Groningen
Thrombosis, Venous
Evaluation Of Fondaparinux (Also Called ARIXTRA) 2.5 mg Subcutaneously Once Daily For The Treatment Of Superficial Thrombophlebitis (Also Known As Superficial Vein Thrombosis)
To evaluate fondaparinux 2.5mg subcutaneously once daily for 45 days in the treatment of acute (recent) superficial thrombophlebitis.
- Trial name
- NCT00443053
- Where
- 227 sites in Bulgaria, Czechia and 15 more
- Volunteers
- 3,002 people
- Sponsor
- GlaxoSmithKline
Thrombosis
Diagnostic Approach of Deep Vein Thrombosis in Primary Care
To asses the cost-effectiveness of implementing different diagnostic strategies in patients with clinical assessment of suspected deep vein thrombosis (DVT) at first presentation in primary care.
- Trial name
- NCT01595763
- Testing
- D Dimer and ultrasonography
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Venous Thromboembolic Disease, Pulmonary Embolism
CHIPs-VTE Study in Hospitalized Patients to Prevent Hospital-Acquired Venous Thromboembolism
Although pharmacologic and mechanical methods to prevent VTE are safe, effective, cost-effective, and advocated by authoritative guidelines,many studies continue to demonstrate that these preventive methods are significantly…
- Conditions
- Venous Thromboembolic Disease, Pulmonary Embolism, Venous Thromboembolism, Deep Venous Thrombosis
- Trial name
- NCT04211181
- Testing
- The multifaceted interventions, Routine VTE prophylaxis
- Where
- China
- Volunteers
- 5,800 people
- Sponsor
- China-Japan Friendship Hospital
Venous Thrombosis, Pulmonary Embolism
Study of Apixaban for the Prevention of Thrombosis-related Events in Patients With Acute Medical Illness
The purpose of this study is to learn if apixaban can prevent blood clots in the leg (deep vein thrombosis [DVT]) and lung (pulmonary embolism [PE]) that sometimes occur within patients hospitalized for acute medical illness, and…
- Trial name
- ADOPT (NCT00457002)
- Testing
- Apixaban, Enoxaparin
- Where
- 296 sites in United States, Argentina and 33 more
- Volunteers
- 6,758 people
- Sponsor
- Bristol-Myers Squibb
Deep Venous Thrombosis, Pulmonary Embolism
STA®-Liatest®D-Di-Exclusion of Venous Thromboembolism
The purpose of this study is to demonstrate the ability of STA® Liatest® D-Di combined with a clinical pretest probability (PTP) to safely exclude pulmonary embolism (PE) or Deep Venous Thrombosis (DVT) in a 3 month follow-up.
- Conditions
- Deep Venous Thrombosis, Pulmonary Embolism, D-dimer
- Trial name
- DiET (NCT01221805)
- Where
- 18 sites in United States, Canada and 3 more
- Volunteers
- 2,040 people
- Sponsor
- Diagnostica Stago