Clinical trials: DWI
Drug-impaired Driving
Oral Fluid Screening Devices
This research includes the evaluation of a checklist and on-site screening devices to pre-select drivers suspected of being drug-impaired.
- Trial name
- NCT00571207
- Testing
- On-site oral fluid screening devices, Checklist: drug recognition expert
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Breast LN
Comparative Evaluation of Diffusion Weighted MRI And Ultrasonography In The Detection of Breast Lesions
This study aims to conduct a comparative evaluation of Diffusion Weighted MRI (DW-MRI) and Ultrasonography (US) in detecting breast lesions.
- Trial name
- NCT06744101
- Testing
- Evaluate the effectiveness of Diffusion Weighted MRI (DWI) in detecting breast lesions., Compare Sensitivity and Specificity of DWI and USG
- Where
- Pakistan
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Superior University
Thorax Cancer
Diffusion Weighted Magnetic Resonance Imaging for the Characterization of Solitary Pulmonary Lesions
The purpose of this study, is to investigate the value of diffusion weighted imaging on the differential diagnosis of solitary pulmonary lesions.
- Trial name
- DWIMRICSPL (NCT02482181)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- ÇAĞLAYAN ÇAKIR
Crohn Disease, Bowel Cleansing
DWI MR-enterography Without or With Bowel Cleansing to Assess Intestinal Inflammatory Activity in the Follow-up of Crohn's Disease
Since 2009, many studies tend to prove the effectiveness of diffusion-weighted MR-enterography in the assessment of inflammatory activity in IBD compared to standard MR-enterography, with the emergence of new radiological scores…
- Conditions
- Crohn Disease, Bowel Cleansing, Apparent Diffusion Coefficient
- Trial name
- ENTEDIF (NCT05354609)
- Testing
- MR-enterography
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Rectum Cancer, Pelvic Cancer
Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers
This study evaluates the reliability of functional MRI measurements in pelvic disease through quantifying repeatability and reproducibility, using healthy volunteers.
- Trial name
- PILLAR (NCT06458725)
- Testing
- Magnetic Resonance Imaging (MRI)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Cannabis, Driving Under the Influence
Cannabis Edibles and Simulated Driving
The goal of this human laboratory experiment is to determine the acute and residual effects of a range of doses of orally administered cannabis edibles on driving simulator performance in people who use cannabis recreationally.
- Trial name
- NCT06595576
- Testing
- Cannabis - Low Dose (2 mg), Cannabis - Medium Dose (10 mg), Cannabis - High Dose (20 mg)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Drunk Driving, Alcohol Drinking
Design and Evaluation of an In-Vehicle Real-Time Drunk Driving Detection System
To analyze driving behavior of individuals under the influence of alcohol while driving in a real car. Based on the in-vehicle variables, the investigators aim at establishing algorithms capable of discriminating sober and drunk…
- Conditions
- Drunk Driving, Alcohol Drinking, Impaired Driving
- Trial name
- DRIVE (NCT05796609)
- Testing
- Driving under the influence of alcohol
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Gastric Cancer
Study on the Value of Three DWI Scanning Sequences in Staging of Gastric Cancer
Accurate staging is critical for effective gastric cancer treatment planning. Conventional DWI (C-DWI) has limitations in image quality due to magnetic field inhomogeneity, which hampers precise T staging.
- Trial name
- NCT06735105
- Testing
- Scanning parameter
- Where
- China
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Yunnan Cancer Hospital
Driving Impaired
Validation of Alcohol Level Identification Using DRIVESC
This pilot study will evaluate the feasibility and acceptability of using a commercially available DRIVESC fitness-to-drive measurement tool to detect alcohol-induced impairment in healthy adult participants.
- Trial name
- NCT07282405
- Testing
- DRIVESC, Alcohol
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Driving Under the Influence, Cannabis-impaired Driving
In-Vehicle Real-Time Cannabis Influenced Driving Detection
The goal of this clinical trial is to evaluate whether in-vehicle sensor data can be used to detect cannabis-impaired driving in healthy adult recreational cannabis users.
- Trial name
- REVELIO (NCT07401628)
- Testing
- Cannabis (THC)
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Bern
Binge Alcohol Consumption, Risk Behavior, Health
A Family-Based Alcohol Preventive Intervention for Latino Emerging Adults
The purpose of the proposed study was to develop a family-based drinking prevention intervention for Latino emerging adults (EAs) and Latino parents of EAs.
- Conditions
- Binge Alcohol Consumption, Risk Behavior, Health, Driving Under the Influence, High-Risk Sex
- Trial name
- LEA (NCT05437081)
- Testing
- Latino Emerging Adults (LEA)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Underage Drinking, Driving Under the Influence
Parent Intervention to Reduce College Student Drinking and Consequences
College students' alcohol use continues to be a major public health problem. Among the many consequences of this risky behavior are impaired driving and impaired passenger fatalities.
- Conditions
- Underage Drinking, Driving Under the Influence, Drinking, Teen, Drinking, College
- Trial name
- NCT04247191
- Testing
- P-Chat, PBI, P-Chat+
- Where
- United States
- Volunteers
- 2,061 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cannabis Intoxication
The Impact and Detection of Driving Impairments Associated With Acute Cannabis Smoking
This study was authorized by the California Legislature (Assembly Bill 266, the Medical Marijuana Regulation and Safety Act to help with detection of driving under the influence of cannabis.
- Trial name
- NCT02849587
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Drunk Driving
Leveraging Transdermal Alcohol Monitoring to Reduce Drinking Among DWI Defendants
The current study will evaluate the efficacy of contingency management (i.e., reinforcement for avoiding heavy drinking) among adults arrested for drunk driving and who are at risk for ongoing heavy drinking.
- Trial name
- NCT03638596
- Testing
- Contingency Management, Control
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Ischemic Optic Neuropathy, Optic Neuritis
Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.
The aim of the project is to create a new, non-invasive and safe protocol for the early diagnosis of various types of optic neuropathies with the use of diffusion magnetic resonance imaging
- Conditions
- Ischemic Optic Neuropathy, Optic Neuritis, Compressive Optic Neuropathy, Traumatic Optic Neuropathy
- Trial name
- NCT05353413
- Testing
- Neuroimaging, VEP - visual evoked potential, Ophthalmology examination.
- Where
- Poland
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Stroke
Understanding Motor Function in Stroke Patients and Their Functional Brain Reorganization Using Ultra High-field MRI
The MOTIF-STROKE study is embedded within the BrainSync project, aiming to develop innovative strategies for motor rehabilitation of the upper limb.
- Trial name
- MOTIF-STROKE (NCT07339813)
- Testing
- Functional MRI (fMRI) Acquisition
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Commissariat A L'energie Atomique
Alcohol Drinking, Alcohol Intoxication
Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving
This project aims to demonstrate the feasibility of a scalable behavioral intervention using smartphone-paired breathalyzers and text message aimed at reducing drinking and driving among individuals who report heavy drinking.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Impairment, Drive
- Trial name
- BESAFE (NCT03335735)
- Testing
- Loss-framed text message, Gain-Framed text message
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Myeloma
Machine Learning in Myeloma Response
Diffusion-weighted Whole Body Magnetic Resonance Imaging (WB-MRI) is a new technique that builds on existing Magnetic Resonance Imaging (MRI) technology.
- Trial name
- MALIMAR (NCT03574454)
- Testing
- Machine Learning (ML)
- Where
- 3 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Healthy Volunteers
Optimal Low B-value in Intravoxel Incoherent Motion Diffusion-weighted MR Imaging of the Brain
Our research aims to reveal whether the low b-values distribution and the number of NEX for each b value will influence the accuracy of pseudodiffusion parameter derived from IVIM in brain.
- Trial name
- NCT02411864
- Testing
- different low b-values distribution
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Fertility Disorders
Non-invasive Detection of Male Infertility With FDG-PET/MRI (Spectroscopy and DWI)
The aim of the study is to examine the value of the new MRI techniques (spectroscopy and DWI), and FDG-PET in prognostication of male infertility.
- Trial name
- NCT03250195
- Testing
- PET/MRI
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet