Clinical trials: DWI
Ovarian Cancer
Imaging Study in Advanced Ovarian Cancer
The aim of the study is the assessment of tumour sites critical for the achievement of optimal cytoreduction in patients with advanced ovarian cancer using Ultrasound, CT and WB-DWI/MRI.
- Trial name
- ISAAC (NCT03808792)
- Testing
- Ultrasound, CT and WB-DWI/MRI
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Charles University, Czech Republic
Binge Alcohol Consumption, Risk Behavior, Health
A Family-Based Alcohol Preventive Intervention for Latino Emerging Adults
The purpose of the proposed study was to develop a family-based drinking prevention intervention for Latino emerging adults (EAs) and Latino parents of EAs.
- Conditions
- Binge Alcohol Consumption, Risk Behavior, Health, Driving Under the Influence, High-Risk Sex
- Trial name
- LEA (NCT05437081)
- Testing
- Latino Emerging Adults (LEA)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Glioblastoma, Anaplastic Astrocytoma
Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma
The purpose of this study is to find out if performing additional Magnetic Resonance Image (MRI) scans of the subjects' brain during each week of the radiation treatment of their high-grade glioma will help improve the radiation…
- Conditions
- Glioblastoma, Anaplastic Astrocytoma, Astrocytoma, Anaplastic Oligodendroglioma
- Trial name
- NCT06108206
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Carotid Stenosis, Brain Ischemia
Correlation Between Laboratory Markers and Origin of New Brain Ischemic Lesions After Carotid Stenting
New brain ischemic lesions are detected in about 50% of patients undergoing carotid artery stenting (CAS). The aim was to assess correlation between selected laboratory markers and occurrence of new brain infarctions after CAS.
- Conditions
- Carotid Stenosis, Brain Ischemia, Laboratory Problem
- Trial name
- NCT02310191
- Testing
- Carotid stenting
- Where
- Czechia
- Volunteers
- 81 people
- Sponsor
- University Hospital Ostrava
Underage Drinking, Driving Under the Influence
Parent Intervention to Reduce College Student Drinking and Consequences
College students' alcohol use continues to be a major public health problem. Among the many consequences of this risky behavior are impaired driving and impaired passenger fatalities.
- Conditions
- Underage Drinking, Driving Under the Influence, Drinking, Teen, Drinking, College
- Trial name
- NCT04247191
- Testing
- P-Chat, PBI, P-Chat+
- Where
- United States
- Volunteers
- 2,061 people, healthy volunteers welcome
- Sponsor
- Penn State University
Systemic Lupus Erythematosus
Pulse Corticosteroid Therapy and Effect on Brain Water Diffusivity
In daily clinical use, pulse high dosis corticosteroids are used to treat cerebral edema in different pathological situations ( surgery, trauma, tumors...).
- Trial name
- NCT00527176
- Where
- Belgium
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Transaortic Transcatheter Aortic Valve Implantation
Intraprocedural Intraaortic Embolic Protection With the EmbolX Device in Patients Undergoing Transaortic Transcatheter Aortic Valve Implantation
Study hypothesis: Reduction of cerebral embolic lesions during transcatheter aortic valve implantation by the use of an embolic protection device.
- Trial name
- TAo-EmbolX (NCT01735513)
- Testing
- Intra-aortic embolic protection management system; Embol-X
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Essen
Glioma, Neoplasms
Study on Neuroepithelial Tumor Grading and Pseudoprogression After Glioma Therapy Using Advanced Functional MRI Techniques
Contrast-enhanced MRI is the most common way for evaluating neuroepithelial tumor grading and monitoring for tumor recurrence,but the ability to predict tumor behavior remains very limited.In this study, the investigators will…
- Trial name
- NCT02622620
- Volunteers
- 86 people
- Sponsor
- Tang-Du Hospital
Cannabis Intoxication
The Impact and Detection of Driving Impairments Associated With Acute Cannabis Smoking
This study was authorized by the California Legislature (Assembly Bill 266, the Medical Marijuana Regulation and Safety Act to help with detection of driving under the influence of cannabis.
- Trial name
- NCT02849587
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Surgically Staged Endometrial and Cervical Carcinoma, Cervical Cancer: Invasive Disease, FIGO Stage 1B1 or Higher
Diagnostic Accuracy of MRI, DWI MRI, FDG-PET/CT and FEC PET/CT in the Detection of Lymph Node Metastases in Surgically Staged Endometrial and Cervical Carcinoma
This is a prospective diagnostic performance study which compares three new imaging methods with the current standard imaging method for the diagnosis of metastatic lymph nodes.
- Conditions
- Surgically Staged Endometrial and Cervical Carcinoma, Cervical Cancer: Invasive Disease, FIGO Stage 1B1 or Higher, Endometrial Cancer, Stage 1A With Myometrial Invasion or Any Higher Stage and Grade 3
- Trial name
- MAPPING (NCT01836484)
- Testing
- Diffusion-weighted MRI, Fluorodeoxyglucose-18-PET/CT, Fluoro-ethyl-coline-PET/CT
- Where
- 7 sites in United Kingdom
- Volunteers
- 162 people
- Sponsor
- Barts & The London NHS Trust
Drunk Driving
Leveraging Transdermal Alcohol Monitoring to Reduce Drinking Among DWI Defendants
The current study will evaluate the efficacy of contingency management (i.e., reinforcement for avoiding heavy drinking) among adults arrested for drunk driving and who are at risk for ongoing heavy drinking.
- Trial name
- NCT03638596
- Testing
- Contingency Management, Control
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Intracerebral Hemorrhage
Prospective Cohort Study of Intracerebral Hemorrhage
The investigators design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification，cost-effective ,treatments and prognosis of Chinese hospitalised adult…
- Trial name
- POSTER (NCT04707105)
- Where
- China
- Volunteers
- 856 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Whole Body Imaging, Magnetic Resonance Imaging
Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis
Whole body MRI will be performed in patients with neurofibromatosis Type 1 PURPOSE 1: To determine the total tumor load (neurofibroma) and to diagnose plexiform neurofibromas or malignant peripheral nerve sheath tumors.
- Conditions
- Whole Body Imaging, Magnetic Resonance Imaging, Neurofibromatosis 1, Diffusion Magnetic Resonance Imaging
- Trial name
- NEFIMAR (NCT01777451)
- Testing
- Additional imaging or surgery
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Prostate Cancer
Multiparametric MRI for Prostate Cancer Localization and Characterization: New Methods
The purpose of this study is to determine the ability of several new MRI techniques (MR elastography, dynamic contrast-enhanced MRI with gadofosveset, and oscillating gradient diffusion) to determine the location, size, and grade…
- Trial name
- NCT01761812
- Testing
- MRI with gadofosveset and MR elastography
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Sunnybrook Health Sciences Centre
High Grade Brain Tumor
Histopathologic Evaluation of High Grade Brain Tumors by High Order Diffusion Tensor Imaging
This study will examine the use of a variation of standard magnetic resonance imaging (MRI) called diffusion tensor MRI (DT-MRI), in order to evaluate the peripheral white matter infiltration of high grade brain tumors.
- Trial name
- TeDi-C2 (NCT01699269)
- Testing
- peritumoral glial cell infiltration
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Clermont-Ferrand
Rectal Neoplasms
Predicting RadIotherapy ReSponse of Rectal Cancer With MRI and PET
The purpose of this study is to investigate if PET/CT and MRI scans performed early in treatment and six weeks after treatment can predict the response of rectal cancer following chemotherapy and radiotherapy.
- Trial name
- PRISM (NCT02233374)
- Testing
- Early MRI and PET/CT - 2 weeks after commencing chemo/RT, Late MRI and PET/CT 6 weeks post chemo/RT
- Where
- Australia
- Volunteers
- 27 people
- Sponsor
- Royal North Shore Hospital
Drink Driving
The Study of KAP on Drink Driving in Jiangsu Province in China
Conduct a KAP survey before and after intervention and describe the current knowledge, attitudes and behaviors on drink driving in public and analyse the influential factors to provide rational strategies to enhance the awareness…
- Trial name
- KAP (NCT02062268)
- Testing
- health education & law enforcement
- Where
- China
- Volunteers
- 3,565 people
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Urinary Bladder Neoplasm
Role of Diffusion -Weighted MRI in Evaluation of Urinary Bladder Masses
Urinary bladder cancer is a common malignant tumor of the urinary tract in both men and women. Proper management of the urinary bladder cancer depends on the stage of the lesions.
- Trial name
- NCT05097105
- Testing
- MRI
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Carotid Artery Disease, Stroke Prevention
Diffusion Weighted-MRI Based Evaluation of the Effectiveness of Endovascular Clamping During Carotid Artery Stenting With the Mo.Ma Device.
The purpose of this study is to detect new ischemic lesions after carotid artery stenting (with the Cristallo Ideale stent), in patients with high grade carotid artery stenosis, by diffusion-weighted magnetic resonance imaging…
- Trial name
- DESERVE (NCT00798512)
- Testing
- Carotid artery stenting
- Where
- 6 sites in Germany, Italy and 1 more
- Volunteers
- 127 people
- Sponsor
- Invatec S.p.A.
Acute Ischemic Stroke
Identification of Stroke Patients ≤ 3 and ≤ 4.5 Hours of Symptom Onset by Fluid Attenuated Inversion Recovery (FLAIR) Imaging and Diffusion Weighted Imaging (DWI)
The aim of the study is to evaluate the use of combined fluid attenuated inversion recovery (FLAIR) imaging and diffusion weighted imaging (DWI) as surrogate marker of lesion age within the first 6 hours of ischemic stroke in…
- Trial name
- PRE-FLAIR (NCT01021319)
- Where
- 2 sites in Germany
- Volunteers
- 643 people
- Sponsor
- Götz Thomalla, MD