Clinical trials: DWI-MRI
Pancreatic Adenocarcinoma
Prospective Evaluation of MRI Biomarkers in Pancreatic Ductal Adenocarcinoma
This is a prospective cohort study in participants with pancreatic adenocarcinoma who are undergoing surgical resection. Participants will have up to two magnetic resonance imaging (MRI) scans with and without intravenous…
- Trial name
- NCT02775786
- Testing
- MRIs with and without intravenous contrast (up to 2)
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Columbia University
Heart Disease
Prevalence of Delirium in Patients Undergoing Cardiac Surgery
The objective of this study is to determine prevalence of postoperative delirium and confusion in patients undergoing cardiac surgery.
- Trial name
- NCT00242151
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Prostate Neoplasms, Toxicity Due to Radiotherapy
Prostate Cancer Stereotactic Radiotherapy
Primary purpose of the study is to develop a stereotactic radiation treatment (RT) to prostate cancer which minimizes treatment related toxicity.
- Trial name
- ESKO (NCT02319239)
- Testing
- Fractionation, hypofractionated, stereotactic fractionation
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Tampere University Hospital
Liver Metastases, Hepatocarcinoma
Use of DwI-MR to Predict Chemotherapy Response of Liver Metastases and Hepatocarcinoma
One of the most recent and interesting field of diagnostic imaging is diffusion-weighted MR imaging (DW-MRI). Various studies evaluated the application of DW-MRI to diffuse liver disease and focal liver lesions providing…
- Trial name
- NCT01411579
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Stefano Colagrande
Uterine Cervical Neoplasms
MRI (Including Spectroscopy and Fat-Saturations and Diffusion-Weighted Imaging) in Cervical Cancer
To detect differences in MR spectroscopy, diffusion weighted MR, diffusion tensor imaging (DTI) or dynamic contrast enhancement (DCE) MR imaging between primary cervical tumors and normal cervical tissue.
- Trial name
- MRI (NCT01060033)
- Testing
- MR Spectroscopy, Fat-Saturation and Diffusion-Weighted Imaging, Dynamic Contrast Enhancement MRI (MR-DCE)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Washington University School of Medicine
Breast Cancer
Breast Cancer Screening With Diffusion-weighted MRI in Women at High Risk for Breast Cancer
A prospective observational multicenter study to compare the outcome of breast cancer surveillance using mammography, breast US, contrast-enhanced MRI, and diffusion-weighted MR imaging (DWI) as a screening tool, in the high-risk…
- Trial name
- NCT03835897
- Where
- South Korea
- Volunteers
- 890 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Head and Neck Cancer
Measurement of Head and Neck Tumor Hypoxia With PET-MRI
This study is designed to evaluate the performance of advanced magnetic resonance (MR) imaging in the assessment of tumor hypoxia using [18F]EF5 positron emission tomography (PET) as a reference in head and neck cancer patients.
- Trial name
- EF5NECK (NCT05246475)
- Testing
- PET-MRI
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Turku University Hospital
Brain Ischemia
Magnetic Resonance Imaging to Investigate Silent Strokes During Neck and Skull Angioplasty
This study will use magnetic resonance imaging (MRI) to determine if silent strokes occur during angioplasty of the blood vessels in the neck or skull.
- Trial name
- NCT00015717
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Recurrent Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer
Diffusion-weighted MRI for Individualized Radiation Therapy Planning of Lung Cancer
This clinical trial studies diffusion-weighted magnetic resonance imaging (MRI) in identifying and localizing tumors in patients with non-small cell lung cancer undergoing radiation therapy.
- Conditions
- Recurrent Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer, Stage IIB Non-small Cell Lung Cancer, Stage IIIA Non-small Cell Lung Cancer
- Trial name
- NCT02059889
- Testing
- diffusion-weighted magnetic resonance imaging, 4-dimensional computed tomography, fludeoxyglucose F 18
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Prostate Cancer Metastatic
Whole-Body Diffusion-Weighted Magnetic Resonance Imaging (MRI) as a Response Biomarker for Metastatic Prostate Cancer
The skeleton is the most frequent organ of distal metastases in prostate cancer, often representing the only site of metastatic disease.
- Trial name
- iPROMET (NCT05078151)
- Testing
- Whole-Body Diffusion Weighted MRI
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- Vall d'Hebron Institute of Oncology
Sarcoma
Novel Applications for Sarcoma Assessment
This research aims to improve the way of deciding whether a lump in soft tissue such as fat or muscle is a type of cancer called a soft tissue sarcoma, or if it is benign (non-cancerous).
- Trial name
- NASA (NCT06073314)
- Testing
- Quantitative MRI
- Where
- United Kingdom
- Volunteers
- 186 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Kidney Cancer
Rein 3D PRINT MECHANICS
The goal of this innovative project is to evaluate the correspondence between several imaging modalities for characterizing the elasticity of healthy and pathological renal tissue which could help improve the realism of 3D prints…
- Trial name
- Rein3DP-M (NCT06525831)
- Testing
- MR-elastography exam, Ultrasound exam
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Pancreas Cancer, Duct Cell Adenocarcinoma, Pancreas Adenocarcinoma
Diagnostic Value of DWI-MRI for Detection of Peritoneal Metastases in High-risk Pancreatic Ductal Adenocarcinoma.
Diffusion-weighted magnetic resonance imaging (DWI/MRI) has been described in recent literature as a highly sensitive and specific modality for the detection of peritoneal metastases (PM).
- Conditions
- Pancreas Cancer, Duct Cell Adenocarcinoma, Pancreas Adenocarcinoma, Peritoneal Metastases, Peritoneal Carcinomatosis
- Trial name
- DWI-PDAC (NCT05340569)
- Testing
- Whole-body diffusion-weighted magnetic resonance imaging
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Gastrointestinal Stromal Tumors
WB-DWI for Early Prediction of Therapy Response in Patients With Advanced Metastatic GIST Treated With Regorafenib
The purpose of this study is to evaluate WB DWI as early predictor of response to treatment with regorafenib or placebo in patients with advanced metastatic GIST.
- Trial name
- NCT01265979
- Testing
- Whole body diffusion MRI
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ischemic Stroke
Total Posterior-circulation Infarct Volume in Basilar Artery Stroke
Preprocedural predictors of outcome in patients with acute basilar artery occlusion (ABAO) who underwent endovascular treatment (EVT) remain controversial.
- Trial name
- TPCIV-ABAO (NCT04650022)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Montpellier
Nephroblastoma (Wilms Tumour)
DWI in the Diagnosis of Histological Types of Nephroblastoma in Children
Initially, or after preoperative chemotherapy, patients with a kidney tumor are examined on 3T MR scanner or 1.5T MR scanner. A standard MRI study of the abdomen with contrast enhancement is performed.
- Trial name
- NCT04814758
- Testing
- MRI DWI sequence (ADC values)
- Where
- Russia
- Volunteers
- 230 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Pyocele; Sinus
Diffusion Weighted MRI Enables Differential Diagnosis Between Pyocele and Mucocele
Diffusion MRI should allow for differentation of pus and simple retention in the paranasal sinuses, but this remained to be determined
- Trial name
- NCT06323798
- Testing
- MRI
- Volunteers
- 20 people
- Sponsor
- Central Hospital, Nancy, France
Acute Ischemic Stroke
Tenecteplase for Late-Window Stroke Guided by DWI-FLAIR Mismatch
The goal of this clinical trial is to evaluate the efficacy and safety of tenecteplase administered 4.5-9 hours after stroke onset (defined as the time the patient was first found with symptoms, including wake-up stroke and…
- Trial name
- TRUST-MISMATCH (NCT07540416)
- Testing
- TNK-tPA, Aspirin
- Where
- China
- Volunteers
- 564 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Pancreatic Masses
Mri and Ultrasound Elastography in Pancreatic Masses
To compare transcutaneous ultrasound elstography to Diffusion weighted MRI in differentiating between benign and malignant pancreatic masses.
- Trial name
- NCT06895655
- Testing
- MRI and Ultrasound Elastography
- Volunteers
- 50 people
- Sponsor
- Assiut University
Ovarian Neoplasms
Magnetic Resonance Imaging for Lymph Node Staging in Ovarian Cancer
Advanced epithelial ovarian cancer has high morbidity and mortality. Patients presenting with advanced stage ovarian cancer often have cancer spread to regional lymph nodes.
- Trial name
- MILO (NCT02243059)
- Testing
- Gadofosveset trisodium (Ablavar™ ), MRI
- Where
- Netherlands
- Sponsor
- Maastricht University Medical Center