Clinical trials: Damage Control, open to volunteers
Athetoid CP, Cerebral Palsy (CP)
Comparison of Sensory Integration Therapy and Conventional Physical Therapy on Gross Motor Function in Children With Athetoid Cerebral Palsy: A Randomized Controlled Trial
This is an RCT aiming to explore the comparison of Sensory Integration Therapy and Conventional Physical Therapy on Gross Motor Function in Children with Athetoid Cerebral Palsy
- Trial name
- NCT07611565
- Testing
- Sensory Integration Therapy and Conventional Physical Therapy, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Ibadat International University, Islamabad
Muscle Weakness, Problems Moving Their Arms and Legs
Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults
People with cerebral palsy (CP), muscular dystrophy (MD), spina bifida, or spinal cord injury often have muscle weakness, and problems moving their arms and legs.
- Trial name
- NCT06998134
- Testing
- Extension assist knee ankle foot orthosis (EA-KAFO)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Cerebral Palsy, Congenital
Effects of Hippotherapy in Children With Cerebral Palsy
Cerebral palsy is a group of permanent disorders affecting movement and posture due to non-progressive disturbances in the developing brain.
- Trial name
- NCT07739680
- Testing
- Hippotherapy Program, Special Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fenerbahce University
Primary Sjögren Syndrome
Study on Optimization and Evaluation of Integrated Chinese and Western Medicine for pSS Glandular Damage
ChatGPT In a randomized controlled trial, 136 patients with primary Sjögren's syndrome (pSS) meeting the inclusion criteria were enrolled and randomly divided into two groups of 68 each.
- Trial name
- NCT06519617
- Testing
- Yi Qi Yang Yin Decoction, Hydroxychloroquine Sulfate
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Qingwen Tao
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD)
Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitation program.
- Conditions
- Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder)
- Trial name
- GEN-HOPE (NCT07493096)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healing Hope International
Celiac Disease
Study of DONQ52 in Active Celiac Disease
The main aim is to see how DONQ52 works to improve small intestinal damage and reduce celiac-related symptoms due to gluten exposure, in participants with celiac disease (CeD) attempting to maintain a gluten-free diet (GFD) in…
- Trial name
- NCT07239336
- Testing
- Simulated Inadvertent Gluten Exposure (SIGE) capsule, DONQ52
- Where
- 74 sites in United States, Australia and 1 more
- Volunteers
- 92 people
- Sponsor
- Chugai Pharmaceutical
Hip Arthroscopy, Articular Cartilage Defect
AMIC Compared With Microfracture for Focal Articular Cartilage Damage of the Hip
This is a pilot multi-centre RCT of 40 patients (ages 18-55 years, inclusive) undergoing primary hip arthroscopy with a focal articular cartilage defect of the acetabulum to compare the effect of using autologous matrix-induced…
- Conditions
- Hip Arthroscopy, Articular Cartilage Defect, Microfractures
- Trial name
- REPAIR (NCT05402072)
- Testing
- Autologous matrix-induced chondrogenesis (AMIC)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McMaster University
Cerebral Palsy (CP)
Spastic Myopathy in Adults With Cerebral Palsy
Cerebral palsy (CP) is indeed the result of a central neurological lesion, but it also involves a lesser-known muscular condition that we refer to as spastic myopathy.
- Trial name
- MYOSPAS-IMC (NCT07293988)
- Testing
- Guided Self-rehabilitation Contract, Conventional therapy group
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Neuroloco
Cerebral Palsy (CP)
Expiratory Muscle Training in Children With Cerebral Palsy
This study aims to examine the effects of expiratory muscle training on posture, trunk control, balance, selective motor control, and respiratory function in children with spastic-type cerebral palsy (CP).
- Trial name
- CP-EMT (NCT07048223)
- Testing
- Expiratory Muscle Training
- Volunteers
- 20 people
- Sponsor
- Istinye University
Spastic Diplegic Cerebral Palsy
Effects of Transcranial Direct Current Stimulation Combined With Virtual Reality on Gait and Self-Esteem in Children With Spastic Cerebral Palsy
Cerebral palsy can affect walking ability, muscle control, functional mobility, and psychosocial well-being in children. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that may…
- Trial name
- NCT07829796
- Testing
- Active Transcranial Direct Current Stimulation, Virtual Reality Rehabilitation, Conventional Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Cerebral Palsy (CP)
Effect of Multidimensional Trunk Training in Children With Cerebral Palsy
This study investigates the effects of a personalized, multidimensional trunk-focused exercise program combined with conventional rehabilitation on postural control, gait, selective motor control, spasticity, activity…
- Trial name
- NCT07034872
- Testing
- Control Group, Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Cerebral Palsy
Intensive Somatosensory Camp for Manual Function and Participation in Children With Unilateral Cerebral Palsy
This study will evaluate whether an intensive day camp that combines somatosensory and motor training for the affected upper limb improves hand function and participation in children with unilateral cerebral palsy more than an…
- Trial name
- CAMPUSENS (NCT07487857)
- Testing
- Somatosensory-Motor Intensive Camp, Motor-Only Intensive Camp
- Volunteers
- 26 people
- Sponsor
- University of Castilla-La Mancha
Cerebral Palsy, Cerebral Palsy Early Intervention
Early Intervention in Cerebral Palsy: Perception-Action vs Neurodevelopmental Therapy
The goal of this clinical trial is to compare two different physiotherapy approaches used in early intervention for children with cerebral palsy.
- Trial name
- NCT07575659
- Testing
- Perception-Action Approach, Neurodevelopmental Therapy (Bobath)
- Volunteers
- 24 people
- Sponsor
- Tuba Derya Doğan
Spastic Cerebral Palsy (sCP)
Virtual Reality Combined With Bobath Therapy for Spastic Cerebral Palsy
Spastic cerebral palsy is a common neurodevelopmental disorder characterized by increased muscle tone, impaired balance, and limitations in motor function, particularly in the lower limbs.
- Trial name
- VR-BOBATH-CP (NCT07392398)
- Testing
- Virtual Reality Combined With Bobath Therapy, Conventional Bobath Therapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tongren Hongxin Kangxin Traditional Chinese Medicine Hospital, Guizhou Province
Cerebral Palsy, Spastic Diplegic Cerebral Palsy
Comparing Mixed Reality and Physical Therapy to Improve Balance and Coordination in Adolescents With Spastic Diplegic Cerebral Palsy
This randomized controlled trial aims to compare the effectiveness of fully immersive Mixed Reality (MR) combined with standard physical therapy versus standard physical therapy alone in improving balance and coordination among…
- Trial name
- NCT07685327
- Testing
- Meta Quest Pro Mixed Reality System, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Ibadat International University, Islamabad
Delayed Onset Muscle Soreness, Exercise-Induced Muscle Damage
Mineral-Infused Clothing for Recovery From Muscle Soreness and Muscle Damage After Exercise
The goal of this clinical trial is to learn whether wearing mineral-infused clothing helps muscles recover after a hard bout of unaccustomed exercise in healthy adults aged 18 to 45 who have not done lower-body resistance or jump…
- Trial name
- PERFICT (NCT07873866)
- Testing
- Mineral-infused garment, Non-infused control garment, Muscle-damaging eccentric exercise (drop jumps)
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- StudySetGo
Cerebral Palsy, Spastic
Effect of Task-Specific Training in an Augmented Reality Context on Upper Limb Function and Activities in Children With Spastic Cerebral Palsy
Children with Cerebral Palsy (CP), a condition that affects movement and coordination, face difficulties in daily activities such as dressing, reaching for objects in high places, and getting up from seats.
- Trial name
- INTERACT (NCT06571929)
- Testing
- INTERACT
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Tracheomalacia, Bronchopulmonary Dysplasia (BPD)
Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention
Children with lung and airway malformations or early structural lung damage face significant challenges, often leading to recurrent respiratory infections, hospitalizations, and decreased quality of life.
- Conditions
- Tracheomalacia, Bronchopulmonary Dysplasia (BPD), Vascular Ring, Cystic Lung Disease
- Trial name
- TRALULALA-AZI (NCT06409299)
- Testing
- Azithromycin 40 MG/ML
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Muscle Damage
Protein Distribution and Leucine Supplementation Effects on Body Composition and Performance in Tactical Athletes
This randomized controlled trial will examine the effects of within-day protein distribution and leucine supplementation on body composition, physical performance, and biomarkers of muscle damage in tactical athletes during an…
- Trial name
- NCT07438158
- Testing
- L-leucine supplementation, Even Protein Distribution, Skewed Protein Distribution (16-hour Protein-Fasting Window)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University