Clinical trials: Damage Muscle
Skeletal Muscle Damage
Recovery Kinetics Following a Soccer Training in Middle-aged Males
This study aims at investigating the recovery kinetics of skeletal muscle damage, neuromuscular fatigue and performance following a single soccer trainning session in middle aged males.
- Trial name
- NCT06260215
- Testing
- ST
- Where
- Greece
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Cerebral Palsy
Classification of Cerebral Palsy Subtypes
This study, conducted at the National Institutes of Health and the Children's National Medical Center, will evaluate how well different physicians agree in how they classify cerebral palsy subtypes based on patient examination.
- Trial name
- NCT00072800
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Exercise Recovery
Post-exercise Therapeutic Modalities on Functional Performance, Muscle Damage and Oxidative Stress of CrossFit® Athletes
Crossfit® is a training modality that consists in functional movements, constantly varied and executed at high intensity. Both training sessions and competitions involve physically demanding activities, which in addition to being…
- Trial name
- NCT06628609
- Testing
- Passive recovery, PBMT-sMF, Shock wave
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Spastic Cerebral Palsy
Effect of Post Isometric Relaxation Technique & Eccentric Muscle Contraction on Hamstring Spasticity in CP
Cerebral Palsy is a disorder of movement and posture due to deficit or lesion of immature brain. Out of all types of cerebral palsy 77.4% is spastic cerebral palsy.
- Trial name
- NCT03708757
- Testing
- Post isometric relaxation - Group I, Eccentric Muscle contraction - Group II
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Muscle Damage
The Effects of Protein Supplementation in Females and Males Following Acute Eccentric Exercise
Examine the impact of the protein supplements leucine, HMB and BCAA on muscle recovery and inflammatory response following acute exercise.
- Trial name
- NCT04679519
- Testing
- Drop Jumps
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Cerebral Palsy
HMB Cerebral Palsy Pilot Study
This is a pilot study of β-hydroxy-β-methylbutyrate (HMB) + Vitamin D3 supplementation in adolescents with cerebral palsy. The primary objective is to quantify safety, compliance, and acceptability of daily combined HMB + Vitamin…
- Trial name
- NCT05384951
- Testing
- HMB + Vitamin D3
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Gillette Children's Specialty Healthcare
Glycogen Storage Disease, McArdle Disease
Carbon-13 Magnetic Resonance Spectroscopy in Glycogen Storage Diseases
The project will use carbon-13 magnetic resonance spectroscopy to assess whether high glycogen levels in skeletal muscle of patients with Glycogen Storage Diseases is a prelude for muscle damage.
- Conditions
- Glycogen Storage Disease, McArdle Disease, Pompe Disease (Late-onset)
- Trial name
- NCT04929002
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cerebral Palsy (CP), Balance
The Effect of Kinesiologic Taping on Trunk Control and Balance in Children With Cerebral Palsy
Title: Effects of Kinesiology Taping on Motor Function, Balance, and Spasticity in Children with Hemiplegic and Diplegic Cerebral Palsy: A Four-Week Study Study Type: Interventional (Clinical Trial) Study Design: Single-group…
- Conditions
- Cerebral Palsy (CP), Balance, Kinesiology Taping, Spasticity
- Trial name
- NCT07188961
- Testing
- kinesiologic taping
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Rumeli University
Muscle Damage, Inflammation
Protein and Recovery From Exercise-induced Muscle Damage
Intense, eccentric resistance exercise causes muscle damage, soreness, inflammation, and a loss of muscle function. Protein-amino acid supplementation before, during, and following damaging resistance exercise may reduce muscle…
- Trial name
- NCT02034721
- Testing
- Protein supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Cerebral Palsy
Effects of Flywheel Exercise on Muscle and Walking Function in Teenagers and Young Adults With Cerebral Palsy
The main purpose of this project is to improve physical function and muscle health in teenagers and young adults with cerebral palsy (CP) by using an eccentric-overload resistance exercise model Specific aims 1.
- Trial name
- CP-Flywheel (NCT03124628)
- Testing
- Flywheel resistance exercise, Weight-stack resistance exercise
- Where
- Sweden
- Sponsor
- Karolinska Institutet
Laser, Muscle; Fatigue, Heart
Photobiomodulation, Cryotherapy Combined With Compression, and Massage for Recovery
Skeletal muscle fatigue is an inevitable phenomenon in the training and competition routine for many crossfit athletes, which can impair their physical performance and predispose them to musculoskeletal injuries.
- Conditions
- Laser, Muscle; Fatigue, Heart, Muscle Damage
- Trial name
- NCT05627141
- Testing
- Photobiomodulation; Cryotherapy, Massage
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Anhanguera
Muscle; Fatigue, Heart, Skeletal Muscle Recovery
Infrared Low-level Laser Therapy Before Intense Progressive Running Test of High-level Soccer Players
Photobiomodulation therapy (PBMT) has recently been used to alleviate postexercise muscle fatigue and enhance muscle recovery, demonstrating positive results.
- Trial name
- NCT03803956
- Testing
- Active PBMT
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Damage Muscle
Spirulina Supplementation In Recovery From Damaging Exercise
Exercise can cause muscle damage, leading to a loss in muscle function, increased muscle soreness and inflammation. Evidence supports the use of nutritional strategies to help recovery. Spirulina is a type of algae.
- Trial name
- SPIRAL (NCT06391957)
- Testing
- Spirulina supplement, Eccentric exercise
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Cerebral Palsy (CP)
Effect of rESWT Session Frequency on Spasticity and Function Assessed by Sonoelastography in Children With Cerebral Palsy
Spasticity is a major contributor to functional limitations in children with cerebral palsy. Radial extracorporeal shock wave therapy (rESWT) has emerged as a non-invasive method for reducing spasticity; however, the optimal…
- Trial name
- CP-rESWT-FREQ (NCT07476690)
- Testing
- Real radial extracorporeal shock wave therapy (rESWT), Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Cerebral Palsy, Spasticity
Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy
The aim of our work is to investigate whether electrical Lateral Cord Stimulation (LCS) causes an inhibitory and modulatory action by indirect cerebellar activation, so releasing spasticity and the spastic syndrome in selected…
- Trial name
- Andreani1 (NCT02199015)
- Testing
- Lateral spinal cord surgical implant of electrodes
- Where
- 2 sites in Argentina, Germany
- Volunteers
- 40 people
- Sponsor
- Juan Carlos M. Andreani MD
Recovery Methods, Exercise and Recovery
Effects of Carnitine Supplementation on Exercise-Induced Muscle Damage: A Randomized Controlled Trial
This clinical study aims to investigate the effects of L-carnitine supplementation on recovery following high-intensity interval exercise in young athletes.
- Conditions
- Recovery Methods, Exercise and Recovery, Exercise Fatigue, Carnitine Ingestion
- Trial name
- NCT07492446
- Testing
- L-Carnitine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Neuromuscular Electrical Stimulation
Can Branched Chain Amino Acids Supplementation Reduce Muscle Damage Induced by Neuromuscular Electrical Stimulation? A Combined Functional and Metabolic Non-invasive Investigation in Healthy Humans
Neuromuscular electrical stimulation (NMES) is commonly used in rehabilitation contexts in order to increase or restore muscle capacities of hypoactive patients or patients with articular trauma.
- Trial name
- NCT01687361
- Testing
- branched-chain amino acids (BCAA) supplementation
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Spasticity, Cerebral Palsy
Oral Baclofen Pharmacokinetics and Pharmacodynamics in Children With Spasticity
Oral baclofen is used commonly to treat spasticity in children with cerebral palsy. Although for adults there is dosing,safety and efficacy information in the package insert, this is not the case for children.
- Trial name
- Best PK/PD (NCT00607542)
- Testing
- baclofen
- Where
- 11 sites in United States
- Volunteers
- 61 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Athletic Performance, Muscle Fatigue
Whole-Body Photobiomodulation Use in Professional Soccer Players During a State Championship
This study aims to investigate the effects of whole-body photobiomodulation on professional soccer players during a state championship.
- Conditions
- Athletic Performance, Muscle Fatigue, Muscle Strength, Sports
- Trial name
- WBPBM-PSC (NCT07224646)
- Testing
- Whole-Body Photobiomodulation (PBM) (Active PBM)
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Cerebral Palsy Spastic Hemiplegic
Improving Hand Movements in Kids With One-Sided Arm Stiffness Cerebral Palsy Through Motion Minder Therapy (MoMT)
Motion Minder Therapy is a targeted intervention for fine motor skill challenges in spastic hemiplegic cerebral palsy children, emphasizing affordability, particularly in middle-income countries like India.
- Trial name
- MoMT (NCT06560281)
- Testing
- Motion Minder Therapy (MoMT)
- Where
- 2 sites in India
- Volunteers
- 10 people
- Sponsor
- Saveetha University