Clinical trials: Daptomycin
Antibiotics, Subcutaneous Injection
Subcutaneous Daptomycin in Healthy Volunteers (DAPTOSC)
Background: Multidrug-resistant bacteria are a major public health problem worldwide, notably due to excess mortality and an increase in the length of hospital stay.
- Conditions
- Antibiotics, Subcutaneous Injection, Daptomycin
- Trial name
- DAPTOSC (NCT04434300)
- Testing
- Daptomycin
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Drug Interactions, Pharmacokinetics
Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin
The purpose of this study is to understand how an antibiotic, rifampin, may change the blood levels of another antibiotic, daptomycin, in the body.
- Trial name
- NCT02097953
- Testing
- Daptomycin, Rifampin
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Utah
MRSA - Methicillin Resistant Staphylococcus Aureus Infection
Vascular Surgical Antibiotic Prophylaxis Study (VSAPS 2)
The current recommended antibiotic, Cefazolin, treatment for vascular surgery, provides coverage only for Methicillin-Sensitive Staphylococcus Aureaus (MSSA), other gram-positive bacteria, and some gram-negative bacteria which…
- Trial name
- NCT01612052
- Testing
- Antibiotic Prophylaxis
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
MRSA Infections
Vancomycin and Daptomycin Plus Cefazolin for Preoperative Vascular Surgery Prophylaxis
This study prospectively selects the patients to examine the effectiveness of the investigators' current standard of prophylaxis prior to vascular surgery and to compare the effectiveness of vancomycin and daptomycin plus…
- Trial name
- NCT00967941
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Diabetic Foot
Outpatient Treatment of Gram Positive Wound Infections in the Diabetic Foot: A Pharmaco-economic Comparison of Daptomycin vs. Vancomycin Based Regimens
The purpose of the study is to evaluate the overall burden to the participant (economic, quality of life, patients satisfaction and freedom from side effects) when treating Gram positive infections of the foot in diabetic adults…
- Trial name
- NCT01133600
- Testing
- Cubicin, Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Clinical Alliance for Research & Education - Infectious Diseases, LLC.
Healthy
Pharmacokinetic Study of Daptomycin in Healthy Chinese Subjects Living in China
The primary objective of this study is to characterise the pharmacokinetics and dose proportionality of daptomycin after single and multiple (once daily) 4mg/kg and 6 mg/kg doses of daptomycin in healthy Chinese volunteers.
- Trial name
- NCT00858325
- Testing
- Daptomycin
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AstraZeneca