Clinical trials: Data Accuracy
Breast Cancer, Metastases
Whole-body MRI for the Detection of Metastasis
Develop and optimize protocols for whole body MRI for detection of metastases. Evaluate diagnostic accuracy through application of optimized protocols for screening of cancer patients.
- Trial name
- WBMRI (NCT02183597)
- Sponsor
- Norwegian University of Science and Technology
Molar Incisor Hypomineralization
Accuracy of Spectrophotometry in Hypomineralized Lesions Treated With CPP-ACPF Dental Mousse: Clinical Study
MIH is a condition with considerable prevalence in the child population. This structural defect, represented by a change in the color of the enamel, can be accompanied by structural loss and great sensitivity.
- Trial name
- ASHLTDMCS (NCT06330272)
- Testing
- Application of dental mousse based on CPP-ACPF
- Where
- Brazil
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Meire Coelho Ferreira
Gather Feasibility Data and User Feedback on Use of a Device in Vivo on Pregnant Volunteers in Their 2nd and 3rd Trimester
Vscan Access R2 Feasibility Evaluation
This study is being done to evaluate if the Vscan Access R2 Ultrasound System can measure Fetal Heart Rate (FHR) in humans when compared against a reference device (GE Corometrics 170 Series Fetal Monitor), and to gather feedback…
- Trial name
- NCT03617419
- Testing
- GE VScan Access R2 Ultrasound System, GE Corometrics 170 Series Fetal Monitor
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Colorectal Tubular Adenoma
Establishment of Big Data Platform and Biobank for Colorectal Tubular Adenoma Lesions
Colorectal tubular adenoma is the most common precancerous lesion of colorectal cancer, and the point is that its precise prevention and treatment can reduce the incidence of colorectal cancer.However, the epidemiological…
- Trial name
- NCT06322225
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Breast Cancer, Complication of Surgical Procedure
Feasibility Study to Evaluate the Use of Patient Reported Complications After Digital Consent
Patient report complication data to our best knowledge has not been studied yet in electronic consent. This study is a feasibility study to assess whether patients will reliably report their complications, the quality of this…
- Trial name
- PRC (NCT06351865)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Perimenopause, Perimenopausal Depression
A Trial to Investigate the Accuracy of a Wearable Device in Collecting Data Related to Perimenopausal Symptoms in Women
The goal of this observational study is to investigate the accuracy of the device in characterizing perimenopausal and menopausal symptoms including vasomotor symptoms, anxiety, sleep quality compared to self-reported symptoms…
- Conditions
- Perimenopause, Perimenopausal Depression, Perimenopausal Insomnia, Perimenopausal Women
- Trial name
- NCT07022925
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- IdentifyHer Limited
Cataract
OCT-PRO Model vs. Clinicians: Cataract Surgery Outcome Prediction
Cataract is the leading cause of blindness worldwide, yet 5-20% of patients fail to achieve satisfactory visual recovery after surgery.
- Trial name
- NCT07713069
- Testing
- OCT-PRO prediction model, Routine Preoperative Counseling
- Volunteers
- 534 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Accurate and Complete Data Acquisition for Clinical Trials
Pilot Study to Enable Electronic Laboratory Data Transfer From Participating Institutions to MediData/RAVE
An initial step toward more accurate and complete data acquisition for clinical trials, the Pediatric Early Phase Clinical Trials Network (PEP-CTN) and Pediatric Brain Tumor Consortium (PBTC) will assess the feasibility of…
- Trial name
- NCT05020951
- Testing
- Medidata RAVE
- Where
- 8 sites in United States
- Volunteers
- 46 people
- Sponsor
- Children's Oncology Group
Infection, Bacterial, Antibiotic Side Effect
Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK)
Getting the right dose of antibiotic promptly is an important part of treating infections. Unfortunately, when an infection is severe (sepsis) the body changes how it processes antibiotics.
- Conditions
- Infection, Bacterial, Antibiotic Side Effect, Antibiotic Resistant Infection, Sepsis
- Trial name
- MD-PK (NCT05950984)
- Testing
- Drug Infusion Pump Monitoring
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- St George's, University of London
Complete and Accurate Statistical Data of 60 Patients, CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately
Analysis of the Effect of Donor CYP3A5 Gene Polymorphism on Early Tacrolimus Concentration and Postoperative Acute Renal Injury After Liver Transplantation
Tacrolimus is the most commonly used immunosuppressant for preventing and treating rejection after liver transplantation. However, its treatment window is narrow, the pharmacokinetic individual differences are large, routine dose…
- Conditions
- Complete and Accurate Statistical Data of 60 Patients, CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately, Postoperative Tacrolimus Concentrations Were Accurately Recorded in 60 Patients, According to the Diagnosis and Grading Criteria of Acute Kidney Injury, the Cases and Grading of Postoperative Acute Kidney Injury in 60 Patients Were Counted
- Trial name
- NCT06319391
- Testing
- CYP3A5*1*、CYP3A5*1*3, CYP3A5*3*3
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziqiang Li
Graft Rejection, Kidney Transplantation
Artificial Intelligence Model for Renal Allograft Rejection Identification, Lesion Quantification and Rejection Risk Prediction Based on Prospective Renal Transplant Pathology and Clinical Multidimensional Data
This prospective research collects leftover kidney biopsy tissue slides and matching routine clinical data from patients who received kidney transplants and underwent standard kidney puncture biopsy at Zhejiang University School…
- Conditions
- Graft Rejection, Kidney Transplantation, Glomerulonephritis, Polyomavirus Infections
- Trial name
- NCT07741552
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Chen Dajin
Coronary Artery Disease, Acute Myocardial Infarction
Heart Cycle Prestudy
In this Prestudy which will be followed by the multicentral GEx- main-trial, the feasibility of a new cardiac rehabilitation device (GEx system) is proved with coronary heart disease patients who participate in cardiac…
- Trial name
- PreGEx (NCT01627457)
- Testing
- Guided Exercise (GEx) system
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- RWTH Aachen University
Breast Cancer
FHIR-Enhanced RealRisks to Improve Accuracy of Breast Cancer Risk Assessments
Electronic health records (EHRs) are an increasingly common source for populating risk models, but whether used to populate validated risk assessment models or to de-facto build risk prediction models, EHR data presents several…
- Trial name
- FHIR (NCT05810025)
- Testing
- RealRisks
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Columbia University
Bladder Cancer
Diagnostic Performance of the Vesical Imaging-Reporting and Data System (VI-RADS) in Detecting Muscle-invasive Bladder Tumour (MIBC) in Clinical Practice: Comparison With Transurethral Resection of Bladder Cancer (TURB) and Evaluation of Diagnostic Accuracy According to Tumour Location
VI-RADS was an observational, prospective, multicenter, no profit study. The aim of the study was to clarify the clinical validity of the Vesical Imaging-Reporting and Data System (VI-RADS) for the assessment of muscle invasion…
- Trial name
- VI-RADS (NCT06337591)
- Testing
- VI-RADS
- Where
- 3 sites in Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Data Accuracy, Bleeding Control
Gingival Retraction for Digital Scan Data
The study aims to identify which retraction method offers optimal balance between tissue displacement, scan clarity, and patient comfort, particularly in the esthetic zone, while avoiding the use of CBCT.
- Trial name
- NCT07119281
- Testing
- Group A: Cordless paste with astringent (EXP): Expasyl (Acteon PVT LTD), Group B: Cordless paste without astringent (MF): Magic FoamCord (Coltene Whaledent AG), Group C: Laser troughing (LT): Diode laser (iLase; Biolase Inc.)
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Coronary Artery Disease
Diagnostic Performance of Noninvasive Fractional Flow Reserve From Computed Tomography
Fractional Flow Reserve derived from computed tomography(FFRCT) is a novel method for determining the physiologic significance of coronary artery disease (CAD), which will help physicians in clinical decision-making and decrease…
- Trial name
- PERFECT (NCT01747317)
- Testing
- FFR (PressureWire)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai 10th People's Hospital
Breast Neoplasms
Development and Application of Accurate Detection Technology Based on Multimodal Data of Breast Cancer Comobid Depression
This study is a prospective, observational clinical research aimed at establishing a multimodal database encompassing clinical information and gut microbiome data from a sample of over 1,000 breast cancer patients comorbid with…
- Trial name
- NCT06938373
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xiangya Hospital of Central South University
Atrial Fibrillation
Accuracy of Rhythm Detection by a Wearable Smart Watch for Cardiac Arrhythmias (The WATCH-RHYTHM Study)
It is an attempt to see the reliability of the Wearable Smart Watch in identifying atrial fibrillation and other arrhythmias compared to the data detected from ILRs.
- Trial name
- NCT04499807
- Testing
- AFib detection with wearable smart watch
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Hepatocellular Carcinoma, Cholangiocarcinoma, Intrahepatic
Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study
Aim of this prospective national multicenter study is to improve standardization of contrast-enhanced ultrasound (CEUS) in the non-invasive diagnosis of hepatocellular carcinoma (HCC) in high-risk patients.
- Conditions
- Hepatocellular Carcinoma, Cholangiocarcinoma, Intrahepatic, Liver Cirrhosis, Liver Cancer
- Trial name
- ESCULAP (NCT03405909)
- Testing
- contrast enhanced ultrasound (CEUS), MRI, Histology
- Where
- Germany
- Volunteers
- 517 people
- Sponsor
- University Hospital Erlangen
Keratoconus, Forme Fruste Keratoconus
Corneal Biomechanical Properties and Anterior Segment Parameters, in Forme Fruste Keratoconus
The present study attempts to evaluate the diagnostic capacity of a) anterior segment parameters b) biomechanical metrics and c) a combination model, in differentiating Forme Fruste Keratoconus (FFK) from healthy corneas.
- Trial name
- NCT01448408
- Where
- Greece
- Sponsor
- Democritus University of Thrace