Clinical trials: Database
Acute Coronary Syndrome
Retrospective Analysis of the Effect of In-hospital Initiation of PCSK9i on Clinical Outcomes in Chinese ACS Patients
The objective of this study is to investigate the effectiveness of in-hospital initiation of alirocumab combined with statin ± ezetimibe on major cardiovascular events (MACE) in Chinese ACS patients.
- Trial name
- NCT06567418
- Testing
- alirocumab 75mg/2week, statin ± ezetimibe
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Yun Dai Chen
Glioma of Brain
Longitudinal Analysis of the Health-related Quality of Life in Glioma Patients
Gliomas are the most common primary intracranial tumors, representing at least 75% of all primary malignant brain tumors. Histopathologically, gliomas are classified into different subgroups including astrocytomas (60-70%)…
- Trial name
- Glioma2015 (NCT03849430)
- Where
- Belgium
- Volunteers
- 750 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Covid-19, SARS-CoV Infection
Analysing the French COVID-19 Epidemic Using a National SARS-CoV-2 RT-PCR Database
Analysing ths spread of COVID-19 epidemics in a timely manner is key to implementing public health control strategies. The investigators propose to analyse a large set of laboratory SARS-CoV-2 RT-PCR data to explore potential…
- Trial name
- CovPCR (NCT04738331)
- Where
- France
- Volunteers
- 10,000,000 people
- Sponsor
- University Hospital, Montpellier
Advanced Non-small Cell Lung Cancer
Evaluation of Cemiplimab in Combination With Platinum-Doublet Chemotherapy in First-Line (1L) Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) in Adult United States (US) Participants
This multi-year cohort study will assess the real-world safety and effectiveness of first Line (1L) treatment with cemiplimab in combination with platinum-doublet chemotherapy across advanced NSCLC participant subgroups defined…
- Trial name
- NCT06269133
- Testing
- REGN2810, Platinum-doublet chemotherapy
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Regeneron Pharmaceuticals
Head and Neck Cancer
TEST: Registry for Endoscopic Head and Neck Surgery
The goal of this data review research study is to create a registry database using information (data) collected from patients who have had Endoscopic Head and Neck Surgery (eHNS).
- Trial name
- TEST (NCT01412749)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- M.D. Anderson Cancer Center
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH), Metabolic Syndrome
ENDOCARE-SCREEN: Metabolic Liver Dysfunction Screening Study
The ENDOCARE-SCREEN study is a single-center, observational, cross-sectional screening study designed to assess the prevalence, phenotypes, and determinants of metabolic dysfunction-associated steatotic liver disease…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH), Metabolic Syndrome, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus
- Trial name
- ENDOCARE-SCREE (NCT07336563)
- Where
- Poland
- Volunteers
- 10,000 people
- Sponsor
- Jarosław Drobnik
Health Related
PCOS (Polycystic Ovarian Syndrome) Patients
The Prospective Cohort Study for PCOS Patients was set up to investigate the short- and long-term health consequences in Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University, China.
- Trial name
- NCT03991507
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Arm Injuries
Development of a Psychosocial Assessment Database for Reconstructive Hand Transplantation
A prospective multicenter study utilizing standardized instruments for the psychological assessment of hand transplant candidates pre and post-transplant as well as those candidates excluded for transplantation.
- Trial name
- NCT01565187
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Human Metabolomic Responses to Plant Foods, Blood Pressure
Establish a Vegetable Signature Database From Human Metabolomics Responses
Vegetable is well known to prevent chronic disease,however, the mechanism of its nutrients and non-nutrients still remains to be discovered.We design a feeding study which provides plant foods to subjects one by another and…
- Trial name
- NCT01600911
- Testing
- Low phytochemical diet(LPD), high phytochemical diet(HPD)
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Gastric Cancer
A Recurrence Nomogram for Hepatoid Adenocarcinoma of the Stomach
This study aims to develop a nomogram to predict postoperative recurrence of HAS and guide individually tailored surveillance strategies.
- Trial name
- NCT05274464
- Where
- China
- Volunteers
- 261 people
- Sponsor
- Fujian Medical University
Obesity, Overweight
Bariatric Outcomes Longitudinal Database (BOLD)
The primary purpose of the Bariatric Outcomes Longitudinal Database (BOLD) study is to assess the mid- and long-term outcomes of bariatric surgeries and to analyze the relationship between these outcomes and 1) patient…
- Conditions
- Obesity, Overweight, Diabetes
- Trial name
- BOLD (NCT01002352)
- Where
- United States
- Volunteers
- 600,000 people
- Sponsor
- Surgical Review Corporation
Benign Prostate Obstruction (BPO)
SteamOne - Prospective Database for Rezum Water Vapor Therapy of the Prostate
This study is to assess the clinical data of Rezum (water vapor therapy) in patients with BPO (benign prostate obstruction) and male LUTS (lower urinary tract symptoms) in terms of efficacy, durability and safety in a large…
- Trial name
- SteamOne (NCT05495633)
- Testing
- Collection and evaluation of clinical (CROMs) and patient-reported outcomes (PROMs), Analysis of uroflowmetry data by EmanoFlow Mobile Application (App) and Emano Clinic Portal
- Where
- 19 sites in Austria, Germany and 1 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Movement Disorder
Human Movement Database
This study will collect information on the different ways people control limb and body movements. This information will be used to develop a database on normal movements and adaptive movements of people who have diseases that…
- Trial name
- NCT00001252
- Where
- United States
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Leukemia, Promyelocytic, Acute
Impact of a Simplified Patient Care Strategy to Decrease Early Deaths in Acute Promyelocytic Leukemia (APL) by Maintaining a Database
Acute promyelocytic leukemia (APL) is a very rare type of leukemia. Because it is so rare, many doctors do not have experience treating it. APL has been shown to be curable most of the time.
- Trial name
- NCT02309333
- Where
- 4 sites in United States
- Volunteers
- 117 people
- Sponsor
- Emory University
Pancreatitis
Idiopathic Recurrent Acute Pancreatitis (IRAP)
The purpose of this study is to collect standardized data on the diagnosis and management of idiopathic (unknown cause) recurrent acute pancreatitis.
- Trial name
- IRAP (NCT01133535)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Asthma, Nasal Polyps
Asthma With Nasal Polyposis
Asthma is often associated with various comorbidities that may influence its clinical expression. Among those, chronic rhinosinusitis with nasal polyposis (CRSwNP) is observed in 5% of cases.
- Trial name
- NCT03694847
- Where
- Canada
- Volunteers
- 1,293 people
- Sponsor
- Louis-Philippe Boulet
Atrial Fibrillation
The Comparative Safety and Effectiveness of Warfarin and Dabigatran Prescribed in the Non-valvular Atrial Fibrillation Population With Humana Healthcare Coverage
This study is an opportunity for Boehringer Ingelheim to collaborate with Humana to conduct comparative safety and effectiveness studies of dabigatran and warfarin using real world data from Humana's health plan operations.
- Trial name
- NCT02061748
- Testing
- Observational
- Where
- United States
- Volunteers
- 38,499 people
- Sponsor
- Boehringer Ingelheim
Healthy Volunteers
Spine Reference Parameters on EOS Imaging
The lumbar pain caring consists from a 3D reconstruction of the spine obtained to scan or radiography, determining the lumbar pain cause and gravity, to propose a conservative treatment in first intention or a adapted spine…
- Trial name
- EOS-SPINE (NCT01406743)
- Testing
- EOS™ Acquisition
- Where
- France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Psoriatic Arthritis, Psoriasis
Incidence of Psoriatic Arthritis Among Psoriasis Patients Newly Initiated With Secukinumab in a US Claims Database and a UK Registry
This was a retrospective cohort study to assess the incidence rate of psoriatic arthritis (PsA) among psoriasis (PsO) patients newly initiated on secukinumab or any biologics/apremilast (small molecule).
- Trial name
- NCT06172426
- Where
- Switzerland
- Volunteers
- 1,171 people
- Sponsor
- Novartis Pharmaceuticals
Malignant Melanoma
Follow-up of a National Cohort of Melanoma Resectable Stage II, Stage III or IV Patients or Unresectable Primary
Prevention of melanoma can be efficient but mortality remains unchanged and 15 to 20% of patients still die from melanoma. Indeed metastatic melanoma is a heterogeneous highly and multiple mutations driven cancer.
- Trial name
- MelBase (NCT02828202)
- Testing
- Biological, Tissular, Quality of life
- Where
- 27 sites in France
- Volunteers
- 6,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris