Clinical trials: Day-to-Day Function
Contraception
Study to Investigate Compliance With the Oral Contraceptive SH T00186D in a Flexible Extended Regimen Supported by a Dispenser With a Reminder Function
The objective of the study is to evaluate the effect of the dispenser's buzzer function on compliance with daily tablet intake of an ethinyl estradiol (EE) + drospirenone (DRSP) containing oral contraceptive (OC) in a flexible…
- Trial name
- NCT01257984
- Testing
- BAY86-5300
- Where
- 43 sites in France, Germany and 3 more
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Bayer
Sarcopenia, Physical Exercise
Efficacy of the Consumption of a Spinach Extract on Muscle Function in Subjects Over 50 Years of Age
Controlled, randomized, single-center, double-blind clinical trial, with two parallel branches depending on the product consumed, to measure the efficacy of a supplement extracted from spinach on muscle strength in subjects over…
- Trial name
- SPISAR (NCT04612127)
- Testing
- Dietary supplement consumption and physical exercise
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Physical Activity, Aerobic Fitness
Active School. A School-based Intervention to Increase Childrens Daily Physical Activity Level.
This study seeks to explore whether increased physical activity in school affects children's executive function, aerobic Fitness and childrens self-regulation. The "Active school" study was a 10-month randomized controlled trial.
- Conditions
- Physical Activity, Aerobic Fitness, Executive Function
- Trial name
- NCT03436355
- Testing
- Physical activity
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- University of Stavanger
Multiple Sclerosis
The Effects of FES in a Variety of Walking Conditions in People With MS
The aim of this study is to measure the difference in the walking performance when functional electrical stimulation (FES) is on and off in people with MS that present foot drop under different 'real life' conditions, i.e.
- Trial name
- NCT03410498
- Testing
- Incremental shuttle walk test
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Healthy
Effects of FTY720 on Heart and Lung Functions in Healthy Volunteers
This study is designed to assess the effects of two doses of FTY720 on lung (pulmonary) and cardiac (heart) functions in healthy volunteers.
- Trial name
- NCT00416845
- Testing
- FTY720
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Novartis
Cardiovascular Disease, Osteoporosis
The Effect of Soy Isoflavone Supplementation on Endothelial Function
A randomized double blind controlled trial was conducted to evaluate the effect of daily supplementation with soy isoflavone 100 mg/day for 12 months on 182 postmenopausal women aged 47 to 60 years at subdistrict South Jakarta…
- Trial name
- NCT01463436
- Testing
- soy isoflavone, control group
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Trisakti University
Healthy
Feasibility & Characterization of Project: EVO Monitor Cognitive Measurements
This is an open-label study in adults to assess at-home Project: EVO Monitor measurements over repeat play cycles. The study has three arms:playing multiple times per day, once daily, and once weekly for 4 to 8 weeks.
- Trial name
- NCT02792296
- Testing
- Project: EVO Monitor
- Where
- 2 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Akili Interactive Labs, Inc.
Physical Activity, Gerontology
Integrated Care Analysis Response to Exercise in Community-dwelling Elders
One of the main challenges of ageing is to prevent the onset of mobility disability and its co-morbidities. Screening the risk of mobility disability in community-dwelling elders is therefore very important and at the uppermost…
- Trial name
- ICARE (NCT04798404)
- Testing
- Multimodal exercise intervention
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cognitive Function, Day-to-Day Function
Cognitive Control and Physical Exercise
The purpose of this study is to test the hypothesis that aerobic exercise and a computer-based cognitive intervention leads to improved cognitive function accompanied by increases in gray matter density and changes in functional…
- Trial name
- NCT01183819
- Testing
- Space Fortress, Aerobic Exercise, Stretching
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Columbia University
Fatigue Syndrome, Chronic, Inflammation
Evaluation of the Effects of Treatment With Bioarginin C in Adult Subjects Belonging to the Post-Covid Day Hospital
Long Covid could be much more frequent than it is thought to be. Few dwell on the great problem represented by the post covid syndrome.
- Trial name
- BC (NCT04947488)
- Testing
- Bioarginina C
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Milan
Healthy Volunteer
A Study of Aleglitazar in Combination With Ibuprofen in Healthy Volunteers
This randomized, double-blind, placebo-controlled, parallel group study will investigate the safety and tolerability, and the effect of aleglitazar in combination with ibuprofen on renal function, renin-angiotensin system and…
- Trial name
- NCT01188317
- Testing
- aleglitazar, ibuprofen
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Cognitive Change, Stress, Psychological
Acute and Chronic Effects of Avena Sativa on Cognition and Stress
The flavanoid and terpene phytochemicals present in wild green oat interact with multiple mechanisms relevant to brain function; including those which would modulate cognition and stress.
- Conditions
- Cognitive Change, Stress, Psychological, Mood
- Trial name
- NCT03689348
- Testing
- Avena sativa
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy
Effect of Azimilide Dihydrochloride on Renal Function
This study will assess the effect of multiple dosing of 125 mg azimilide on glomerular filtration rate (GFR) and total creatinine clearance (GFR + active secretion) in healthy subjects.
- Trial name
- NCT00318838
- Testing
- Azimilide dihydrochloride
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Forest Laboratories
Physical Inactivity
Tele-video to Improve Daily Activity
This pilot study will test the feasibility of pairing a social network-based approach with a 6-week Occupational Therapist (OT)-led intervention administered remotely (via Zoom) to increase physical function and activity among…
- Trial name
- T-VIDA (NCT06007664)
- Testing
- Tele-Video to Improve Daily Activity
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Normal and Impaired Renal Function
A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function
This study is a Phase 1, open-label, parallel group, multiple dose study, in subjects over 18 years, to evaluate the safety, tolerability, and pharmacokinetics of one-hour intravenous infusion of MTP-131 administered for 7…
- Trial name
- NCT02436447
- Testing
- MTP-131
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Stealth BioTherapeutics Inc.
Cognitive Decline, Focus Deficit
Effects of Auri Super Mushroom Daily Gummies on Cognitive Health
This is a single-arm, open-label, virtual clinical trial evaluating the cognitive health effects of Auri Super Mushroom Daily Gummies in a population of 35 adult participants over 8 weeks.
- Trial name
- NCT07198399
- Testing
- Auri Super Mushroom Daily Gummies
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Auri Nutrition
Alzheimer's Disease, Mild Cognitive Impairment
System-IGF-1 Pathway and Alzheimer's Disease
The aim is to assess the relationship between levels of IGF-I system components and cognitive status in patients with Alzheimer's disease (AD), in elderly subjects with normal cognitive function, and in patients with mild…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Cognitive Function 1, Social, Control With Normal Activities of Daily Living
- Trial name
- SIGAL (NCT00647478)
- Where
- France
- Volunteers
- 693 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Erectile Dysfunction
A Study of Visual Effects of Erectile Dysfunction Medications Dosed Daily for Six Months
This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the effects on vision of six months of daily dosing of 5 mg tadalafil or 50 mg sildenafil compared with placebo.
- Trial name
- NCT00333281
- Testing
- tadalafil
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Irritable Bowel Syndrome
A Phase I, Randomized, Placebo-controlled, Double Blind, Repeat Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Gastrointestinal Transit Time and Pharmacodynamic Biomarkers of GSK3179106 in Normal Subjects
The current study is designed to assess the safety, tolerability, pharmacokinetics (PK), gastrointestinal (GI) transit time and pharmacodynamic (PD) biomarkers of repeat oral doses of GSK3179106 administered for 14 days in normal…
- Trial name
- NCT02798991
- Testing
- GSK3179106
- Where
- Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obesity, Poor Glycemic Control
The Consumption of Beef on Appetite and Cognitive Function
The purpose of the main study is to determine whether the daily consumption of protein-rich meals containing high quality, lean beef products improves appetite control and cognitive function during a weight maintenance diet.
- Conditions
- Obesity, Poor Glycemic Control, Dietary Interventions
- Trial name
- NCT02614729
- Testing
- Standard Protein-Plant, Even Distribution (SP-PLANT-EVEN), Standard Protein-Beef, Even Distribution (SP-BEEF-EVEN), High Protein-Beef, Even Distribution (HP-BEEF-EVEN)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia