Clinical trials: Daytime Sleepiness
Sleep Deprivation, Sleep
Effects of Napping in Sleep-Restricted Adolescents
To examine the neurobehavioural responses to two successive cycles of sleep restriction and recovery in adolescents, and to determine the benefits of napping on cognitive performance, alertness, and mood.
- Trial name
- NCT02838095
- Testing
- Nap
- Where
- Singapore
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Seasonal Allergic Rhinitis
Fluticasone Furoate Treatment of Daytime Somnolence and Cognitive Performance in Seasonal Allergic Rhinitis
The hypothesis is that treating hay fever patients who had daytime sleepiness and slowed thinking because of the hay fever will improve when treated with an effective anti-hay fever medication, an intranasal steroid, that is will…
- Trial name
- NCT00997620
- Testing
- Fluticasone furoate Nasal Spray 110 mcg
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Western Sky Medical Research
Excessive Daytime Sleepiness, Obstructive Sleep Apnea (OSA)
Validating a Novel Driving Simulation-based MWT Against the Standard MWT in an OSA-cohort Challenged by CPAP-withdrawal
In brief, the proposed study will evaluate a recently proposed naturalistic, driving simulation test to identify and measure sleepiness behind the wheel, one of the most underestimated causes of road accidents.
- Conditions
- Excessive Daytime Sleepiness, Obstructive Sleep Apnea (OSA), CPAP Treatment, Driving Simulator Performance
- Trial name
- DS-MWT2 (NCT06872593)
- Testing
- CPAP-withdrawal, Test Sequence
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Stefan Lakämper
Sleep Apnea
Spanish Registry of Patients With Sleep Apnea and Daytime Sleepiness
Multicenter, observational and prospective study, in which patients referred to the sleep unit with suspected apnea will be recruited obstructive sleep.
- Trial name
- HYPNOSA (NCT06514482)
- Testing
- Diagnosis
- Where
- Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hospital San Pedro de Logroño
Insomnia
Digital Sleep Program for College Students with Insomnia
This randomized controlled trial (RCT) study aims to evaluate the effectiveness of a digital-based multimodal sleep management program compared to a waitlist control group in improving sleep-related outcomes, including insomnia…
- Trial name
- DSP-CS (NCT06853106)
- Testing
- Waitlist control group, digital-based multimodal sleep management program
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Sleep, Relaxation
Sleep and Morning Wellbeing Study
The study will be a prospective randomized, controlled clinical study. There will be interventional treatment for a total of 30 days. The subjects will complete questionnaires throughout the study at pre-specified timepoints.
- Conditions
- Sleep, Relaxation, Stress, Daytime Sleepiness
- Trial name
- NCT07311434
- Testing
- Sleep Supplement
- Where
- United States
- Volunteers
- 331 people, healthy volunteers welcome
- Sponsor
- Athletic Greens International
Obstructive Sleep Apnea
Study to Determine the Effectiveness of Pillar Palatal Implants to Treat Obstructive Sleep Apnea
The Pillar palatal implant procedure is a minimally invasive and commercially available treatment for mild to moderate obstructive sleep apnea (OSA) in the United States and Europe.
- Trial name
- NCT00307957
- Testing
- Pillar Palatal Implants
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Narcolepsy, Excessive Daytime Sleepiness
A Phase 1, Single Dose Study of JZP-386 to Evaluate Safety, Pharmacokinetics and Pharmacodynamics
This study is being conducted to evaluate the safety, tolerability, blood distribution and effectiveness single ascending doses of JZP-386 compared to doses of Xyrem® and placebo.
- Trial name
- NCT02215499
- Testing
- Sodium Oxybate, JZP-386
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Concert Pharmaceuticals
Excessive Daytime Somnolence, Sleep Deprivation
Start Times and Restful Sleep
The purpose of this study is to evaluate the efficacy of later school start times in increasing student sleep, and examine the association between later start times and physical activity, screen time, and commute time.
- Trial name
- STaRtS (NCT04049682)
- Testing
- Delayed School Start Time
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Daytime Sleepiness
Community-Level Daytime Sleepiness: Social-Environmental Determinants, Consequences, and Impact of Sleep Apnea
The purpose of this study is to examine daytime sleepiness in a community context. This includes examining sleepiness in a large sample in terms of social/behavioral/environmental predictors and health-related outcomes, as well…
- Trial name
- NCT04176042
- Testing
- Track 1, Track 2
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Sleep, Circadian Rhythm
Morning Bright Light Therapy and Daytime Functioning in University Students
This study tests whether a week of morning bright light therapy changes how well healthy young adults sleep and how alert, positive, and mentally sharp they feel during the day.
- Conditions
- Sleep, Circadian Rhythm, Daytime Sleepiness, Mood
- Trial name
- BLIGHT (NCT07685262)
- Testing
- Bright light therapy (10,000 lux light box)
- Where
- Hong Kong
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Excessive Sleepiness, Shift-work Disorder
Clinical Trial of Solriamfetol for Excessive Sleepiness Related to Shift Work Disorder
In this research study the investigators want to learn more about whether the medication Solriamfetol improves daytime sleepiness in workers who start work at very early times (between 3 and 6am).
- Trial name
- NCT04788953
- Testing
- Solriamfetol Oral Tablet
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Charles A. Czeisler, PhD, MD
Poor Quality Sleep
Project REST: Club Sports
Evidence suggests that student athletes frequently experience sleep problems and are aware of the impact of sleep loss on mental and physical outcomes.
- Trial name
- NCT07103759
- Testing
- Refrain from caffeine techniques, Project REST Platform
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Sleepiness, Daytime, Fatigue
Lifestyle Medicine Strategies for Combating Sleepiness and Fatigue in Professional Drivers
Sleep has a number of health benefits, including memory and learning, vitality and energy as well as high quality of life levels.
- Conditions
- Sleepiness, Daytime, Fatigue, Sleep Disorders, Circadian Rhythm
- Trial name
- HighWay2Health (NCT05096130)
- Testing
- Lifestyle Medicine Strategies
- Where
- Greece
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Thessaly
Parkinson's Disease
Circadian Rhythms and Sleep-Wake Cycles in Parkinson's Disease
Disruption of sleep and alertness is one of the most disabling non-motor symptoms of Parkinson's disease (PD). Mechanisms leading to impaired sleep and alertness in PD are not well understood, and treatment options remain…
- Trial name
- NCT01742182
- Testing
- Light exposure
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hypersomnia in Children
Amylase and Hypersomnia
Hypersomnia is defined as a reduced ability to remain awake during the day. There are basically two types of central hypersomnia: narcolepsy and idiopathic hypersomnia.
- Trial name
- Amylase (NCT01926405)
- Testing
- saliva collection
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Sleep Disturbance
Bonafide Sleep Supplement for Menopausal Women With Sleep Complaints
This open-label study was designed to evaluate whether a daily dietary sleep supplement could improve sleep quality and related daytime well-being in menopausal women aged 40 to 65 with sleep complaints.
- Trial name
- NCT07839312
- Testing
- S-Adenosyl Methionine (SAMe), Propyl Gallate, Gamma-Aminobutyric Acid (GABA), L-Theanine, and Magnesium Glycinate
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Acid Reflux Disease, Obstructive Sleep Apnea
Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea
The purpose of this study is to determine if using Pantoprazole decreases your daytime sleepiness and improves your reaction time when compared to using a placebo (sugar pill).
- Trial name
- NCT00307944
- Testing
- Pantoprazole
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Sleepiness, Fatigue
Integral Physiological Adaptations to Carbohydrate Periodization
The purpose of this study is to examine the effect of long-term carbohydrate periodization protocols on sleep architecture, sleep quality, daytime sleepiness, physical performance, body composition, gut microbiome, and miRNA in…
- Conditions
- Sleepiness, Fatigue, Feeding Patterns, Daytime Sleepiness, Excessive
- Trial name
- IPACP (NCT05464342)
- Testing
- Evening LGI Carbohydrate Consumption Group, Evening HGI Carbohydrate Consumption, Evening NO-CHO Carbohydrate Consumption
- Where
- 2 sites in Cyprus, Greece
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Sleep
The Effect of Acupressure on the Sleep Quality and Daytime Sleepiness
This randomized controlled trial evaluates the effect of acupressure application on nurses' sleep quality and daytime sleepiness providing care in surgical clinics.
- Trial name
- NCT04800939
- Testing
- Acupressure, Plasebo acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University