Clinical trials: Decay, Dental
Bacterial Infections, Dental Caries
Hydrogen Peroxide Fumigation in Dental Office Environment
The study's null hypothesis posits no significant difference in bacterial levels in the dental office environment before and after implementing hydrogen peroxide (H₂O₂) fumigation.
- Conditions
- Bacterial Infections, Dental Caries, Aerosol Disease
- Trial name
- NCT06100848
- Testing
- Microbiological analysis after Caries treatment, Microbiological analysis after Caries treatment and fumigation
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Caries
Effect of CPP-ACP With/Without Fl on White Spot Lesion,Salivary pH and fl Release in High Caries Risk Patients
Effect of CPP-ACP pastes with/without Fluoride on White spot lesion progression, salivary pH and fluoride release in high caries risk Patients, over 3 month period using VistaCam, Digital pH meter and Selective ion electrode.
- Trial name
- NCT03656432
- Testing
- CPP-ACP paste
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Effect of Erythritol and Xylitol on Dental Caries Prevention in Children
This study aims at demonstrating the effect of erythritol and xylitol lozenges on preventing the new caries lesions and the possible remineralization effect of both polyols on incipient caries lesions.
- Trial name
- NCT01062633
- Testing
- A, erythritol, xylitol, C, sorbitol
- Where
- Estonia
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Dental Caries in Children
Efficacy of the Use of Silver Diamine Fluoride and Sodium Fluoride Varnish for the Treatment of Caries in Children
The goal of this observational study is to identify the efficacy of silver diamine fluoride 38% followed by sodium fluoride varnish 5% in a population with untreated dental caries age range 4 to 12 years old.
- Trial name
- NCT05638217
- Testing
- Silver diamine fluoride 38% followed by Sodium fluoride varnish 5%
- Where
- Bolivia
- Volunteers
- 199 people
- Sponsor
- Universidad Mayor de San Simón
Teledentistry
Accuracy of Teledentistry for Diagnosis and Treatment Need in Dental Caries Detection Versus Clinical Examination on a Group of Egyptian Children: A Diagnostic Accuracy Study
The aim of this study is to assess the accuracy of teledentistry for diagnosis and treatment need in dental caries detection versus clinical examination on a group of Egyptian children.
- Trial name
- NCT06600360
- Testing
- Teledentistry
- Volunteers
- 102 people
- Sponsor
- Cairo University
Dental Caries
Ozonized Gel vs Gaseous Ozone Against S. Mutans in Deciduos Molars Caries
The aim of this study is to verify, through bacteriological analysis, the efficacy of reducing the bacterial load referred to the presence of Streptococcus Mutans in carious lesions of viable deciduous molars by application of…
- Trial name
- NCT06641323
- Testing
- Ozonized gel, Ozonized water
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- University of Pavia
Dental Caries
Miswak Versus Standard Measures to Prevent the Incidence of Caries Young Egyptian Adults: A Randomized Controlled Clinical Trial
Objectives: Aim of the study The objective is to conduct an RCT to evaluate the effectiveness of miswak in comparison with standard caries preventive measures for the prevention of new carious lesions in high caries risk…
- Trial name
- NCT03732040
- Testing
- miswak stick, Miswak plus tooth brushing and tooth paste, Standard preventive measures (tooth brushing , interdental cleaning and mouth rinse use containing CHX and Fluoride)
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Decay
Effect of Therapeutic Measures in Dental Caries Reduction in Children With Primary Dentition From Medellín City
The propouse of this study is to evaluate some combined preventive measures, of easy application in children under 6 years old as education, brush teeth, fluoride free tooth paste,fluoridated tooth paste, professional cleaning…
- Trial name
- NCT00475618
- Testing
- topical fluoride varnish application., professional cleaning, No fluoride toothpaste
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- CES University
Remote Maintenance Training Program
Wheelchair Maintenance Training Program
The objective of this research study is to assess the effectiveness of a remote wheelchair maintenance training program, and to determine methods which may increase overall success of an online training program.
- Trial name
- NCT03909061
- Testing
- Wheelchair Maintenance Training
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- University of Pittsburgh
Dental Caries
Comparative Study of Experimental Dental Adhesive With and Without Phosphoric Acid Pretreatment
The intent of this study is to evaluate the clinical performance of an experimental dental bonding agent for use with dental restorative composites with and without pretreatment of the tooth dentin and enamel using phosphoric…
- Trial name
- NCT02071953
- Testing
- Experimental adhesive w/out phosphoric acid in post. rest., Experimental adhesive with phosphoric acid in post. rest.
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Pulpitis - Reversible, Occlusal Caries
Evaluation of Cytokines Level as an Indicator of Pulp Inflammation and Its Relation to the Success Rates of Pulpotomy in Primary Molars Affected With Proximal Versus Occlusal Decay
pulpotomy will be done I primary molars with occlusal or proximal decay and level of cytokines will be measured as an indicator for pulp inflammation levels
- Conditions
- Pulpitis - Reversible, Occlusal Caries, Proximal Caries
- Trial name
- NCT07171229
- Testing
- Pulpotomy, Measuring Cytokines level
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Children, Dental Caries
A Comprehensive Oral Health Intervention Program for Preschool and Primary School Children in Suzhou
This study aims to evaluate the effectiveness of a comprehensive oral health intervention program among preschool and primary school children in Suzhou, China.
- Trial name
- NCT07808203
- Testing
- Comprehensive Oral Health Intervention
- Volunteers
- 2,040 people, healthy volunteers welcome
- Sponsor
- Soochow University
Vitamin D Status
Vit D Receptor Gene Polymorphism
The present cross-sectional observational study was conducted after the university ethical committee approved the research (NU/CEC/2020/0339). This study included 376 adults in the age group of 18-40Yrs.
- Trial name
- VITAMIN D GENE (NCT05931705)
- Testing
- questionnaire
- Where
- India
- Volunteers
- 376 people
- Sponsor
- Ajman University
Dental Caries, Dental Plaque
Effect of Xylitol- Versus Erythritol-Sweetened Mints on Plaque ATP-Bioluminescence Readings
This study will assess the effectiveness of erythritol and xylitol in suppressing biofilm activity, using both within-subject and between-group comparisons.
- Trial name
- NCT07902323
- Testing
- Xylitol, Erythritol
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Dental Caries
Dental Caries Management by Risk Assessment: Identification and Treatment of Risk Factors Among (IDF) Personnel
Our study is designed as an interventional prospective longitudinal study which examines the Israeli defense force personnel. The population of our study is composed out of the IDF personnel which will be randomly be subdivided…
- Trial name
- CAMBRA (NCT01142440)
- Testing
- behavioral intervention
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Dental Caries
SEALANT-DK: Longevity and Efficacy of 6 Resin Sealants Used for Sealing Permanent Teeth in Children and Adolescents
Background: Occlusal caries is the main reason for restorative therapy in the young permanent dentition, but restorations have limited survival time and may also weaken the tooth.
- Trial name
- SEALANT-DK (NCT02561689)
- Testing
- Fissure sealing
- Where
- Denmark
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries in Children
Pharmacokinetics of Advantage Arrest in Healthy Children 13-Months to 13-Years of Age
The purpose of this study is to further characterize basic pharmacokinetic (PK) parameters in healthy children to contribute to evidence for the safety of silver diamine fluoride (SDF; Advantage Arrest).
- Trial name
- NCT05670743
- Testing
- 38% silver diamine fluoride
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Caries,Dental
Caries-associated Saliva Biomarkers Among Different Races
discover possible differences and develop effective preventative interventions by examining the relationship between salivary biomarkers and caries prevalence across different racial groups and Detect risk factors involved in…
- Trial name
- NCT06838182
- Testing
- Salivary biomarkers tests
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Secondary Dental Caries
Influence of the Number of Layers of a One Bottle Adhesive on the Longevity of Composite Restorations in Primary Molars
The aim of this study is to determinate the influence of an alternative adhesive application protocol (i.e. consecutive application of an extra adhesive layer)on restoration longevity in primary molars.
- Trial name
- NCT01680289
- Testing
- Three adhesive coats, Two adhesive coats
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dental Caries, Tooth Demineralization
Evaluation of Optical Coherence Tomography in Dentistry
Optical coherence tomography (OCT) is a medical diagnostic tool, providing non-invasive, non-radiative and high resolution imaging. OCT has been established since many years in ophthalmology.
- Trial name
- NCT03753256
- Testing
- Transbond XT, Protecto®CaF2Nano, Pro Seal®
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Heidelberg Medical Center
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