Clinical trials: Decision-making
Heart Failure and Reduced Ejection Fraction
Developing a Digital Aid to Improve ICD Decisions
Advanced heart failure, affecting 7 million Americans, has multiple causes and results in greatly increased risk of disability and death.
- Trial name
- NCT07084142
- Testing
- Online, patient-facing decision-making aid (app) with personalized risk information., Implantable Cardioverter Defibrillator (ICD), Online, patient-facing decision-making app without personalized risk information.
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- Stanford University
Decision Making
PROJECT 2 EXAMPLE: Feedback X Prevalence Using Dermatology Stimuli
Imagine that a dermatologist spends the morning seeing patients who have been referred for suspicion of skin cancer. Many of them do, in fact, have skin lesions that require treatment.
- Trial name
- NCT05244122
- Testing
- Feedback, Prevalence
- Where
- United States
- Volunteers
- 1,121 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Opioid Use Disorder, Healthy Volunteers
Measuring the Effects of Neurostimulation on Risky and Ambiguous Decision-Making Capacity in People With and Without Substance Use Disorder
Background: The purpose of this study is to understand how a type of brain stimulation, transcranial magnetic stimulation (TMS), may help those who use opioids such as heroin or methadone.
- Trial name
- NCT06577454
- Testing
- TMS (MagVenture MagPro 100 with MagOption)
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Coronary Artery Disease, Angina Pectoris
Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making
This retrospective study will investigate clinician behavior in diagnosing patients with possible obstructive coronary artery disease who received a Corus CAD (Age/Sex/Gene Expression score - ASGES) result compared to patients…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- CU-PCP (NCT02158754)
- Testing
- Corus CAD (ASGES)
- Where
- 9 sites in United States
- Sponsor
- CardioDx
Advanced Cancer
Development of an Educational Patient Decision Aid (Treatments in Advanced Cancer - Decision Aid, TA-DA) to Promote Shared Decision Making for Third-line or Beyond Palliative Systemic Therapy
To develop an educational patient decision aid for advanced cancer patients to prepare them to have conversations with their clinicians about treatment options (Treatments in Advanced cancer - Decision Aid, TA-DA).
- Trial name
- NCT07009886
- Testing
- Communication
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer
Implementing REmote SymPtom mOnitoring and maNagement (RESPONd)
The goal of this study is to understand if the implementation of a remote symptom monitoring and management program improves outcomes.
- Trial name
- RESPONd (NCT07024329)
- Testing
- Remote Symptom Monitoring and Management, Clinic Team Huddle
- Where
- 4 sites in Canada
- Volunteers
- 1,055 people
- Sponsor
- University of Calgary
Healthy Volunteers
Are Genetic Counselors Screening for Adolescent Suicide Risk?
Background: Suicide is one of the main causes of death for adolescents in the U.S. The most effective way to decrease suicide is by training doctors to recognize the risk factors in their clients.
- Trial name
- NCT02486120
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Effort Based Decision Making, Prosocial Behavior
Effort and Antidepressant Study Test
The aim of this study is to investigate the behavioural effects and neural correlates of increasing serotonin levels in healthy volunteers, through a 7-day course of the SSRI escitalopram, on an effort-based decision-making task…
- Conditions
- Effort Based Decision Making, Prosocial Behavior, Apathy
- Trial name
- EAST (NCT06696482)
- Testing
- Escitalopram 10mg
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Diabetes Mellitus, Type 2, Physician-Patient Relations
Nudge-Based Shared Decision Making and Self-Management in Type 2 Diabetes: A Randomized Trial
This study aims to test whether a communication strategy called "linguistic nudging" can help doctors and patients with type 2 diabetes make better treatment decisions together, and whether this improves patients' ability to…
- Conditions
- Diabetes Mellitus, Type 2, Physician-Patient Relations, Self-management
- Trial name
- NCT07129915
- Testing
- Linguistic Nudging Training, Medication Preference App, Standard Diabetes Care
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Yunxuan Li
Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Computer-Based Survey and Communication Aid in Improving Physician-Patient Communication and Treatment Decision Making in Patients With Metastatic Cancer
RATIONALE: A computer-based survey and communication aid may help physicians and patients to communicate better and help make treatment decisions easier.
- Trial name
- NCT00244868
- Testing
- counseling intervention, educational intervention
- Where
- 3 sites in United States
- Volunteers
- 720 people
- Sponsor
- Fox Chase Cancer Center
Quality of Life, Behavior
Breathing and Decision-Making
The study aims to investigate how slow breathing with prolonged exhalation (i.e., ProlEx breathing) modulates decision-making under risk in healthy participants.
- Conditions
- Quality of Life, Behavior, Stress, Psychological
- Trial name
- ProlEx-MRI (NCT05936684)
- Testing
- Breathing with prolonged exhalation (ProlEx) during risky decision-making, Normal breathing (Eupnea/Control) during risky decision-making
- Where
- Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Solid, Liquid, Central Nervous System Tumors
Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients
The development of next generation sequencing (NGS) techniques, including whole genome (WGS), exome (WES) and RNA sequencing has revolutionized the ability of investigators to query the molecular mechanisms underlying tumor…
- Trial name
- NCT02530658
- Testing
- Study Introduction Visit, Informed Consent Visit, Informed Consent Follow-Up Visit
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- St. Jude Children's Research Hospital
Colorectal Cancer Screening
Large-Scale Implementation of a Decision Aid About Colorectal Cancer Screening
The goal of the project is to improve shared decision making and increase uptake of colorectal cancer (CRC) screening by facilitating the implementation of a decision aid about CRC and screening options in two healthcare systems…
- Trial name
- IDecide (NCT06597955)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cutaneous Squamous Cell Carcinoma, Cutaneous Squamous Cell Carcinoma of the Head and Neck
Needs and Preferences of Patients With Head-neck Cutaneous SCC
The care of patients with high-risk cutaneous squamous cell carcinomas in the head-neck area is complex and requires a multidisciplinary approach. A key component in this care is the need and experience of patients.
- Conditions
- Cutaneous Squamous Cell Carcinoma, Cutaneous Squamous Cell Carcinoma of the Head and Neck, Squamous Cell Carcinoma, Squamous Cell Carcinoma of Head and Neck
- Trial name
- NCT06046625
- Testing
- Regular care with additional administration of a semi-structured interview
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Maastricht University Medical Center
Cardiovascular Diseases, Coronary Artery Disease
Feasibility and Effectiveness of a Real-time Heart Team Approach in Complex CAD
This study is aimed to evaluate the clinical outcomes, efficiency and feasibility of the real-time heart team approach and the conventional heart team approach.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Multidisciplinary Communication
- Trial name
- EHEART (NCT05514210)
- Testing
- heart team meeting and discussion
- Where
- China
- Volunteers
- 490 people
- Sponsor
- China National Center for Cardiovascular Diseases
Scar; Previous Cesarean Section, Vaginal Birth After Cesarean
University of North Carolina-Healthwise Partnership Project on Birth Options Decision Aid
This is pilot quasi-experimental study of women with one or two prior cesarean deliveries who are now pregnant and eligible for a trial of labor after cesarean delivery, to assess whether a decision aid, providing knowledge about…
- Conditions
- Scar; Previous Cesarean Section, Vaginal Birth After Cesarean, Decision Making, Shared
- Trial name
- B-READY (NCT04053413)
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ischemic Stroke, Ischaemic Stroke With Coma
Decision Aid Feasibility Trial for Families of Critically Ill Stroke Patients
Severe strokes, including large artery acute ischemic stroke and intracerebral hemorrhage, continue to be the leading cause of death and disability in adults in the U.S.
- Conditions
- Ischemic Stroke, Ischaemic Stroke With Coma, Intracerebral Hemorrhage, Hemorrhagic Stroke
- Trial name
- NCT04143113
- Testing
- Decision Aid
- Where
- 2 sites in United States
- Sponsor
- University of Massachusetts, Worcester
Clinical Decision-making
Research Abstract Usefulness in Clinical Decision-making
To better understand the extent to which family nurse practitioners (FNPs) might use research abstracts in shaping their clinical decision-making under simulated conditions.
- Trial name
- NCT01255488
- Testing
- Access to EBN-Search (without full-text manuscripts)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Shared Decision Making, Cesarean Section
Shared Decision-Making During Anesthesia Consent for Elective Cesarean Delivery
Shared decision-making (SDM) is the accepted ethical and legal standard for informed consent, but it is not known how it operates in anesthesia consent for cesarean delivery.
- Conditions
- Shared Decision Making, Cesarean Section, Anesthesia, Obstetrical, Informed Consent
- Trial name
- SDM-Consent (NCT07858084)
- Testing
- Observation of anesthesia consent encounter and postpartum questionnaire
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- University of British Columbia
Breast Neoplasms
Decision Support for Women With Breast Cancer
Breast cancer is a common malignancy among women in the United States. There are a variety of treatment decisions that need to be made.
- Trial name
- NCT01447771
- Testing
- Decision control preference scale
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins