Clinical trials: Decompression, Surgical
Spinal Cord Injuries
Treatment for Chronic Spinal Cord Injury: Surgery With Rehabilitation vs Rehabilitation
The purpose of this study is to investigate the efficacy of surgical decompression/untethering, combined with weight bearing rehabilitation, on neurological recovery following chronic spinal cord injury.
- Trial name
- NCT02663310
- Testing
- Surgery, Rehabilitation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Kunming Tongren Hospital
Post-Operative Pain, Lumbar Laminectomy
HTX-011 in Spinal Surgery
This is a Phase 2, multicenter study in subjects undergoing an open lumbar decompression surgery.
- Trial name
- NCT04911062
- Testing
- Bupivacaine HCI without epinephrine, HTX-011, Luer Lock Applicator
- Where
- 12 sites in United States
- Volunteers
- 32 people
- Sponsor
- Heron Therapeutics
Degenerative Spondylolisthesis, Spinal Stenosis
First-In-Human Study of AK1320 Encapsulated Microspheres (AK1320 MS)
The safety and efficacy of AK1320 MS will be evaluated in patients with degenerative spondylolisthesis and concomitant symptomatic spinal stenosis who are undergoing decompression and single level instrumented posterolateral…
- Trial name
- ENHANCE (NCT04483297)
- Testing
- AK1320 MS, Control
- Where
- 7 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Asahi Kasei Therapeutics Corporation
Postoperative Nausea, Postoperative Vomiting
The Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting in Orthognathic Surgery
This study will compare the incidence of postoperative nausea and vomiting during the first 24 hours following corrective jaw surgery (orthognathic surgery) in patients with and without nasogastric tube gastric decompression.
- Trial name
- NCT06422793
- Testing
- No NG tube gastric decompression
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Lumbar Spinal Stenosis
Can Minimally Invasive Decompression Surgery Restore Sagittal Balance in a Patient Population With Sagittal Imbalance and Lumbar Spinal Stenosis
From adulthood onwards, the aging process manifests itself in the spine through loss of disc height and kyphotic deformity. As the general population ages, the prevalence of lumbar degenerative diseases and sagittal imbalance…
- Trial name
- NCT06075355
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Spinal Stenosis, Spinal Cord Compression
Comparative Effectiveness of Microdecompression and Laminectomy for Central Lumbar Spinal Stenosis
Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis.
- Trial name
- NCT02006901
- Testing
- microdecompression, laminectomy
- Where
- Norway
- Volunteers
- 721 people
- Sponsor
- St. Olavs Hospital
Spine Disease, Spinal Stenosis
CEUS For Intraoperative Spinal Cord Injury
Spinal cord injury following posterior decompression in patients suffering from chronic, cervicothoracic spinal cord compression is a known complication with multiple etiologies.
- Conditions
- Spine Disease, Spinal Stenosis, Spinal Injury, Spinal Cord Diseases
- Trial name
- NCT05530798
- Testing
- Definity Perflutren Lipid Microsphere Ultrasound Contrast
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Myelopathy, Neurogenic Bladder
Urinary and Sexual Function Before and After Surgical Decompression of Cervical Myelopathy
Hypotheses: Decompressive surgery of cervical myelopathy will improve bladder function. Decompressive surgery of cervical myelopathy will improve sexual function.
- Conditions
- Myelopathy, Neurogenic Bladder, Erectile Dysfunction, Psychosexual Dysfunctions
- Trial name
- NCT02059798
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- The Catholic University of Korea
Neuropathy Ulnar
Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow
This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE).
- Trial name
- NCT04254185
- Testing
- Simple decompression, Subcutaneous anterior transposition
- Where
- 10 sites in United States
- Volunteers
- 378 people
- Sponsor
- University of Michigan
Degenerative Lumbar Spondylolisthesis, Lumbar Degenerative Disease
Comparison of Endoscopic Lumbar Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion(MIS-TLIF) for Degenerative Lumbar Spondylolisthesis
Comparing the functional and radiographic outcomes in surgical treatment in failed conservative treatment, single-level low grade degenerative lumbar spondylolisthesis between Minimal Invasive Surgery Transforaminal Lumbar…
- Conditions
- Degenerative Lumbar Spondylolisthesis, Lumbar Degenerative Disease, Lumbar Spinal Stenosis
- Trial name
- MIS-TLIF (NCT06749314)
- Testing
- Lumbar Endoscopic - Unilateral Laminotomy for Bilateral Decompression
- Where
- Thailand
- Volunteers
- 66 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Lumbar Spinal Stenosis
The iO-Flex® Study: Evaluation of the Baxano iO-Flex® System for Decompressive Lumbar Surgery
The purpose of this study is to evaluate the clinical performance of the iO-Flex® System in reducing pain and symptom severity in patients with one or two level lumbar spinal stenosis that requires surgery.
- Trial name
- NCT01067014
- Testing
- Baxano iO-Flex® System
- Where
- 18 sites in United States
- Volunteers
- 75 people
- Sponsor
- Baxano Surgical, Inc.
Cubital Tunnel Syndrome
Electrical Nerve Stimulation of the Ulnar Nerve
Cubital tunnel syndrome is caused by compression of the ulnar nerve at the elbow. This leads to symptoms such as chronic hand weakness, numbness and pain.
- Trial name
- ESTIM (NCT02566616)
- Testing
- Ulnar Nerve Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Digestive System Surgical Procedure, Pancreaticoduodenectomy
Impact of the Absence of Nasogastric Decompression After Pancreaticoduodenectomy
The use of nasogastric (NG) decompression after pancreaticoduodenectomy (PD) is a current practice. NG tube is associated with a high rate of morbidity including pulmonary morbidity, delayed gastric emptying and finally an…
- Trial name
- IPOD (NCT02594956)
- Testing
- no nasogastric tube, nasogastric tube
- Where
- France
- Volunteers
- 125 people
- Sponsor
- Rennes University Hospital
Rotator Cuff Shoulder Syndrome and Allied Disorders
Radio-frequency (RF)-Based Plasma Micro-tenotomy for the Treatment of Shoulder Impingement Syndrome
The purpose of this study is to determine whether radio-frequency (RF)-based plasma micro-tenotomy has a positive effective for the treatment of shoulder impingement syndrome with cuff tendinosis.
- Trial name
- RF (NCT01554670)
- Testing
- RF micro-tenotomy
- Volunteers
- 65 people
- Sponsor
- Beijing Hospital
Lumbar Spinal Stenosis
MiDAS III (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study
This is a multi-center, prospective, observational clinical study to compare patient outcomes following treatment with either the mild® procedure or epidural steroid injection in patients with moderate to severe lumbar spinal…
- Trial name
- MiDAS III (NCT01315145)
- Testing
- Percutaneous Lumbar Decompression, Epidural Steroid Injection
- Where
- 27 sites in United States
- Volunteers
- 138 people
- Sponsor
- Vertos Medical, Inc.
Lumbar Degenerative Spondylolisthesis
Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis
This study aims to systematically evaluate the therapeutic efficacy of dual-channel endoscopic spinal decompression versus lumbar decompression with fusion for degenerative lumbar spondylolisthesis.
- Trial name
- NCT07289737
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Spinal Stenosis
Study Comparing Postoperative Treatment After Surgical Decompression for Lumbar Spinal Stenosis.
The aim of the study is to assess the benefit of wearing a lumbar orthosis after surgery for spinal stenosis. It will be evaluated if a post-surgery immobilization for 6 weeks with a lumbar orthosis reduces early recurrence…
- Trial name
- SURGIMMO (NCT05312281)
- Testing
- Device : Lombastab immo. wear for 6 weeks post-surgery the Lombastab Immo
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- SRH Gesundheitszentrum Bad Herrenalb
Lumbar Spinal Stenosis, Spondylolisthesis
Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis
Lumbar spinal stenosis (LSS), is a common disorder of narrowing of the spinal canal in the lower part of the back. This causes discomfort in the legs when standing or walking because of pressure on the spinal nerves.There are…
- Conditions
- Lumbar Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease
- Trial name
- NCT01455805
- Testing
- Minuteman Fusion Implant, surgical decompression
- Where
- 4 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- Spinal Simplicity LLC
Thyroid Associated Orbitopathy
Changes in Orbital Macrovascular and Intraocular Microvascular Blood Flow After Orbital Decompression Surgery in Patients With Thyroid Eye Disease
This study aims to evaluate the effects of balanced orbital decompression surgery in patients with inactive thyroid-associated orbitopathy.
- Trial name
- BOD-VASC (NCT07393230)
- Testing
- Balanced Orbital Decompression Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Lumbar Spinal Stenosis
Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis
This is a single-center, randomized, prospective, double-blind clinical study to assess the clinical application and outcomes with MILD® devices versus epidural steroid injection in patients with symptomatic moderate to severe…
- Trial name
- NCT00995371
- Testing
- MILD® (Minimally Invasive Lumbar Decompression), Epidural Steroid Injection
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Coastal Orthopedics & Sports Medicine