Clinical trials: Decompression, Surgical
Recurrent Cubital Tunnel Syndrome, Recalcitrant Cubital Tunnel Syndrome
Nerve Protection Evaluation: Revision Cubital Tunnel Syndrome Decompression
This single-cohort, prospective case series is designed to evaluate and characterize the use of Axoguard HA+ Nerve Protector™ to protect the ulnar nerve in a first revision cubital tunnel decompression procedure.
- Trial name
- COVERED (NCT06117501)
- Testing
- Axoguard HA+ Nerve Protector™
- Where
- 7 sites in United States
- Volunteers
- 19 people
- Sponsor
- Axogen Corporation
Spinal Metastases
Surgical Spinal Decompression of Metastatic Spinal Cord Compression, Minimal Access Versus Open Surgery
The investigators wish to evaluate the effect of minimal access spinal surgery compared to traditional open surgery spinal surgery in patients with metastatic spinal cord compression.
- Trial name
- NCT01865942
- Testing
- open surgery, Minimal access surgery
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lumbar Spinal Stenosis
Clinical Outcome Study of Minimally Invasive Decompression for Lumbar Spinal Stenosis
The study is a prospective outcome study to evaluate the effectiveness and treatment outcomes of microendoscopic decompressive laminotomy (MEDL) with objective evaluation tools.
- Trial name
- MEDLLSS (NCT00737607)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
Surgery, Pain
Postoperative Music for Orbital Decompression
The purpose of this study is to evaluate the effect of music to the postoperative pain and discomfort after orbital decompression.
- Conditions
- Surgery, Pain, Musth
- Trial name
- NCT04933201
- Testing
- Music, Routine perioperative treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sun Yat-sen University
Thyroid Eye Disease
Twenty-four Hour Intraocular Pressure Patterns in Patients With Uncontrolled Thyroid Eye Disease
Patients with Thyroid Eye Disease (TED) often have enlarged extraocular muscles and higher orbital fat contents due to their disease process.
- Trial name
- NCT01798966
- Testing
- SENSIMED Triggerfish
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sensimed AG
Lumbar Spinal Stenosis, Spondylolisthesis
Sagittal Plane Shear Index for Planning Lumbar Stenosis Surgery
The objective of the clinical investigation is to assess the proportion of lumbar spinal stenosis surgical treatment plans that change when an objective measurement of spinal stability is included and applied following a simple…
- Trial name
- SPSI (NCT03754972)
- Testing
- Sagittal plane shear index (SPSI)
- Where
- 3 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Medical Metrics Diagnostics, Inc
Complications, Postoperative
A Prospective, Randomized Comparison Of Drainage Techniques After One- Or Two-Level Open Posterior Lumbar Decompression Or Decompression And Fusion
This project is being done to understand if a drain reduces recovery problems after surgery, such as infection or the need for more surgery.
- Trial name
- NCT06820736
- Testing
- Drain
- Where
- United States
- Volunteers
- 975 people
- Sponsor
- Twin Cities Spine Center
Trigeminal Neuralgia, Microvascular Decompression Surgery
Assessment in Patients With Essential Trigeminal Neuralgia of Nerve Involvement by MRI in DTI and Functional Connectivity in "Resting State"
Essential trigeminal neuralgia is the most common facial pain. In forms resistant to drug and disabling treatments, surgical treatment may be offered to the patient.
- Conditions
- Trigeminal Neuralgia, Microvascular Decompression Surgery, Diffusion Tensor Imaging
- Trial name
- SENSE (NCT05051072)
- Testing
- Assessment of the trigeminal nerve by diffusion tensor MRI and in "resting state" in the context of essential neuralgia
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Migraine Headaches
Prospective, Multi-Center Evaluation of the Efficacy of Peripheral Trigger Decompression Surgery for Migraine Headaches
According to the peripheral trigger theory of migraine headaches, nociceptive inputs from irritated or compressed cranial nerve branches can lead to neurovascular changes in the brain that cause migraine headaches.
- Trial name
- NCT02351544
- Testing
- Botulinum Toxin Type A, Surgery, Daily headache diary
- Where
- 6 sites in United States
- Volunteers
- 44 people
- Sponsor
- Ohio State University
Hemifacial Spasm, Microvascular Decompression
Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
There have been reports of monitoring LSR during MVD surgery helps predicting the clinical outcome of MVD. However, there have been no evidence of which degree of partial neuromuscular blockade should be performed during LSR…
- Conditions
- Hemifacial Spasm, Microvascular Decompression, Neuromuscular Blockade
- Trial name
- NCT01613781
- Testing
- TOF count-guided partial NMB, T1/Tc guided partial NMB
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Samsung Medical Center
Spinal Instability
CLUBE (UBE Stability / Dynamic Radio)
Degenerative pathologies of the spine affect a large proportion of the increasingly ageing population, and are a major public health issue.
- Trial name
- NCT06904326
- Testing
- Postoperative dynamic radiography
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Clinique Saint Jean, France
Cervical Degenerative Disc Disease, Cervical Stenosis
Minimally Invasive Posterior Decompression of the Cervical Spine
Degenerative stenosis of the cervical spinal canal may be caused by the compression of the posterior part of the dural sac and spinal cord by the hypertrophied ligamentum flavum and facet joints, by the compression of the…
- Conditions
- Cervical Degenerative Disc Disease, Cervical Stenosis, Posterior Spine Surgery
- Trial name
- NCT06995300
- Testing
- minimally invasive decompression via the posterior approach
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
Dysphagia After Anterior Cervical Decompression and Fusion of the Spine
Effect of Intravenous Corticosteroid Injections on Dysphagia After Cervical Spine Surgery
This is a randomized, double-blind, placebo-controlled study to examine the effect of local intravenous steroids following anterior cervical spine surgery on the development of dysphagia in patients.
- Trial name
- NCT02266797
- Testing
- Dexamethasone, Saline
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- NYU Langone Health
Cervical Myelopathy
Activity Monitors as a Measure of Physical Function in Degenerative Cervical Myelopathy
The investigators objective of this research is to compare activity monitor results with standard of care (SOC) question-based outcome measures for degenerative cervical myelopathy patients before and after treatment with…
- Trial name
- NCT04498806
- Testing
- Fitbit
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Spine Metastasis, Early Goal Directed Therapy
Efficacy of Angiographic Embolization vs Non-embolization of Moderate/Poor Vascularized Vertebral Metastases on Intraoperative Bleeding During Surgery Decompression and Vertebral Stabilization.
Although angiographic embolization has been introduced for preoperative management of spine metastases in 1975 and is suggested today by many authors in the management of such pathologies, it needs to be confirmed by RCT.
- Conditions
- Spine Metastasis, Early Goal Directed Therapy, Embolization, Therapeutic, Blood Loss
- Trial name
- Embart (NCT03853434)
- Testing
- Embolization
- Where
- Italy
- Volunteers
- 4 people
- Sponsor
- Istituto Ortopedico Rizzoli
Drain Tube Influence the Postoperative Epidural Haematoma
Does a Drain Tube Influence the Postoperative Epidural Haematoma for Lumbar Biportal Endoscopic Surgery?
The purpose of this study was to evaluate if wound drains could influence postoperative spinal epidural hematoma (POSEH) in biportal endoscopic spinal surgery (BESS) procedures for decompression of lumbar spinal stenosis.
- Trial name
- NCT06290791
- Testing
- two level lumbar decompression with BESS procedure received one drain., two level lumbar decompression with BESS procedure received two drain.
- Where
- China
- Volunteers
- 89 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Spinal Stenosis Lumbar
Full-Endoscopic Decompression vs. Endoscopic Lumbar Fusion for Middle-Aged and Older Adults With Spinal Stenosis
Lumbar Spinal Stenosis (LSS) is a syndrome characterized by anatomical narrowing of the central canal, lateral recess, or intervertebral foramen of the lumbar spine, leading to compression of nerve roots, the cauda equina, and…
- Trial name
- NCT07482826
- Testing
- Full-Endoscopic Decompression, Endoscopic Lumbar Interbody Fusion
- Volunteers
- 176 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Diabetic Polyneuropathy
Surgical Decompression for Diabetic Neuropathy in the Foot
The purpose of the study is to determine whether or not surgical decompression of the common peroneal, tibial, and deep peroneal nerves in the legs of persons with diabetic peripheral neuropathy is effective treatment.
- Trial name
- NCT01006915
- Testing
- Surgery
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Timothy J. Best Medicine Professional Corporation
Low Back Pain, Sciatica
Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain
The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to…
- Conditions
- Low Back Pain, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06275750
- Testing
- Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.)
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital Civil de Guadalajara
Cranial Nerve Diseases, Facial Neuralgia
CSF Leak Following Microvascular Decompression: the Benefit of Routine Postoperative Lumbar Tap
Even at centers with very large experience, the risk of cerebrospinal fluid (CSF) leakage in surgery for microvascular decompression is reported up to 3%. Prevention of leakage is important since meningitis may follow.
- Conditions
- Cranial Nerve Diseases, Facial Neuralgia, Trigeminal Neuralgia, Hemifacial Spasm
- Trial name
- NCT01932255
- Testing
- prophylactic spinal tap, no prophylactic spinal tap
- Sponsor
- St. Olavs Hospital