Clinical trials: Deep Endometriosis
Pelvic Endometriosis, Endometriosis Outside Pelvis
Prospective Evaluation of Near-infrared Fluorescence Imaging Use as a Supportive Tool in Deep Infiltrating Endometriosis Surgery
The aim of the study is to establish a new and more accurate method to visualize the peritoneal changes caused by endometriosis using Indocyanine Green mediated fluorescence imaging.
- Trial name
- GRE-Endo-2 (NCT03935165)
- Testing
- Indocyanine Green
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Catholic University of the Sacred Heart
Endometriosis, Deep Endometriosis
Indirect Ultrasonographic Findings for Parametrial Involvement in Deep Endometriosis
This study evaluated the use of ultrasonographic findings as a first-line imaging tool to raise indirect suspicion of parametrial involvement in women suspected of having severe endometriosis (DE).
- Trial name
- NCT05239871
- Testing
- Ultrasound
- Where
- Italy
- Volunteers
- 1,078 people
- Sponsor
- Simone Ferrero
Endometriosis, Endometriosis Rectum
Clinical Impact of Ultrasound Diagnosis in Bowel Endometriosis
This retrospective single-centre study evaluates how accurately preoperative ultrasound detects bowel involvement in women with deep endometriosis, using surgical findings as the reference.
- Conditions
- Endometriosis, Endometriosis Rectum, Endometriosis Pelvic, Endometriosis Colon
- Trial name
- NCT07900698
- Testing
- preoperative transvaginal ultrasound
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Erasme University Hospital
Endometriosis, Deep Infiltrating Endometriosis
Prospective Trial of [18F]AlF-FAPI-74 for PET Imaging of Fibroblast Activation Protein in Patients With Endometriosis
The goal of this clinical trial is to learn whether [18F]AlF-FAPI-74 PET/CT can help detect endometriosis in adult women who are already scheduled for laparoscopy due to suspicion of deep infiltrating endometriosis or superficial…
- Conditions
- Endometriosis, Deep Infiltrating Endometriosis, Women, Superficial Peritoneal Endometriosis
- Trial name
- EM-FAPI (NCT07876648)
- Testing
- [18F]AlF-FAPI-74 PET/CT
- Where
- Belgium
- Volunteers
- 64 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Endometriosis
Relaxin, Matrix Metalloproteinase-2 and Interleukin-6 in Women With Chronic Pelvic Pain
In our study, by evaluating the serum and vaginal-peritoneal fluid levels of Relaxin, Matrix Metalloproteinase-2 and Interleukin-6 in women over 35 years of age with chronic pelvic pain, the investigators aimed to reveal their…
- Trial name
- NCT06628479
- Testing
- interleukin, enzyme, hormone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Deep Endometriosis
Radiological Diagnostics in Patients With Deep Endometriosis
Endometriosis is a benign, chronic, recurrent disease characterised by the presence of endometrial glands and stroma outside the uterine cavity.
- Trial name
- NCT06799767
- Where
- Italy
- Volunteers
- 94 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Endometriosis, Rectum
Surgery for Lower Rectum Deep Endometriosis (Segmental/Disc) - Prospective Comparison of Digestive Symptoms and Pain
Several studies show a significant drop in pain scores, improved fertility outcomes and amelioration of impaired sexual functioning in women following surgical resection of colorectal endometriosis.
- Trial name
- NCT04398641
- Testing
- Evaluation of pre- and postoperative gastrointestinal functional outcomes
- Where
- 2 sites in Austria
- Volunteers
- 300 people
- Sponsor
- Univ.-Doz. Dr.med.univ. Gernot Hudelist, MSc.
Endometriosis, Adenomyosis of Uterus
Artificial Intelligence Into Ultrasound Diagnostics in Reproductive Medicine
The goal of this observational study is to develop and validate artificial intelligence (AI)-based algorithms that support ultrasound diagnosis of endometriosis, adenomyosis, myometrial masses, uterine malformations, and impaired…
- Conditions
- Endometriosis, Adenomyosis of Uterus, Leiomyoma (Uterine Fibroids), Uterine Neoplasms
- Trial name
- AUDRIE (NCT07810920)
- Where
- Hungary
- Volunteers
- 1,600 people
- Sponsor
- Semmelweis University
Endometriosis, Bowel Endometriosis
Ultrasonographic and Surgical Assessment of Endometriosis by AAGL 2021 Endometriosis Classification
In 2021, an international consensus developed a new endometriosis classification system, called AAGL 2021 Endometriosis Classification, for scoring intraoperative surgical complexity and to examine its correlation with…
- Conditions
- Endometriosis, Bowel Endometriosis, Deep Endometriosis, Ovarian Endometrioma
- Trial name
- ULTRA-AAGL (NCT05291624)
- Testing
- AAGL Endometriosis Classification score - ULTRASOUND, AAGL Endometriosis Classification score - SURGERY
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Piazza della Vittoria 14 Studio Medico - Ginecologia e Ostetricia
Endometriosis
Interaction Between Decidual Cells and NK Cells in Endometriosis
Endometriosis is a chronic gynecological disease characterized by the presence of endometrial-like tissue outside the uterus and is frequently associated with pelvic pain and infertility.
- Trial name
- PAINLESS (NCT07652593)
- Testing
- Biological Sample Collection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hopital Foch
Endometriosis
Incidence of Different Surgical Technics for Colorectal Deep Infiltrating EndoMetriosis on the Post-operative Fertility and Pregnancy Outcomes
Endometriosis is a disease that is very present on the current media scene. Its symptoms are very nonspecific and numerous. (dysmenorrhea, dyspareunia, dyschezia, urinary functional signs, infertility, chronic pelvic pain, etc.)…
- Trial name
- Endo-Metrios (NCT04681898)
- Where
- France
- Volunteers
- 164 people
- Sponsor
- University Hospital, Strasbourg, France
Deep Endometriosis, Chronic Pelvic Pain
Repetitive Transcranial Magnetic Stimulation as an Analgesic Treatment in Endometriosis Chronic Pain : Feasibility
Endometriosis is associated with different types of pain (acute, chronic, excess nociception, neuropathic) generated by different mechanisms in the nervous system.
- Trial name
- ENDOSTIM (NCT03204682)
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Clermont-Ferrand
Bowel Endometriosis
The Application of Probe-based Confocal Laser Endomicroscopy in the Diagnosis of Deep Endometriosis
Endometriosis is defined as the presence of endometrial glands and stroma outside of the uterus.Endometriosis affects 5%-15% of women in the reproductive age.
- Trial name
- NCT02547909
- Testing
- probe-based Confocal Laser Endomicroscopy, Cellvizio, fluorescein 10%
- Where
- Israel
- Sponsor
- Dr. Ofir Harnoy MD
Endometriosis, Endometriosis, Rectum
Patient Reported Outcomes After Surgery for Rectal Endometriosis
To describe the difference in patient reported outcomes after conservative treatment in comparison to radical rectal surgery in patients with deep endometriosis infiltrating the rectum (up to 15cm from the anus with at least…
- Conditions
- Endometriosis, Endometriosis, Rectum, Endometriosis-related Pain, Endometriosis; Bowel
- Trial name
- PROCURE (NCT04204707)
- Testing
- PROMS
- Where
- 2 sites in Belgium, Hungary
- Volunteers
- 294 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Endometriosis, Endometriosis-related Pain
Conventional Laparoscopy Versus Robotic Surgery for Pain Relief in Patients With Deep Infiltrating Endometriosis
Background: Endometriosis is a common disease, affecting women in their reproductive age suffering from infertility, adnexal masses and chronic pelvic pain, obstruction of the bowel or urinary tract.
- Conditions
- Endometriosis, Endometriosis-related Pain, Endometriosis Pelvic
- Trial name
- NCT05362838
- Testing
- robotic-assisted laparoscopy, Conventional laparoscopy
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Endometriosis-related Pain, Endometriosis
Pelvic Neuro-Angiogenesis in Deep Endometriosis
Endometriosis is observed in one out of every ten women in society, causing endometrial cells to be found outside their normal location in the body and proliferate in other locations, leading to fibrosis in the tissue due to the…
- Conditions
- Endometriosis-related Pain, Endometriosis, Deep Endometriosis, Endometriosis; Peritoneum
- Trial name
- NCT06286371
- Testing
- Laparoscopic Endometriosis Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Uludag University
Endometriosis
Effect of Cannabinoid (THC / CBD 50%) on Hyperalgesia in Patients With Deep Endometriosis
This study evaluates the treatment of the symptoms of deep endometriosis with a cannabinoid derivate.
- Trial name
- EdomTHC (NCT03875261)
- Testing
- Cannabinoid treatment
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- David Garcia Cinca
Cholecystitis, Endometriosis
Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery
This is a two period cross-over study randomizing patients undergoing laparoscopic surgery into 2 different groups: group 1 in which patients receive "deep neuromuscular blockade" in the beginning portion of their laparoscopic…
- Conditions
- Cholecystitis, Endometriosis, Bowel Obstruction, Fibroids
- Trial name
- NCT02812186
- Testing
- Deep to Moderate NMB, Moderate to Deep NMB, Rocuronium
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Stony Brook University
Endometriosis, Deep Endometriosis
Robotic Versus Laparoscopic Surgery for Deep Endometriosis
The objective of this study is to examine whether robot-assisted laparoscopy is superior compared to conventional laparoscopy as regards to patient outcome.
- Conditions
- Endometriosis, Deep Endometriosis, Surgery
- Trial name
- ROBEndo (NCT05179109)
- Testing
- Minimally invasive surgery
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- University of Oulu
Endometriosis
A Study of the Potential Risk Factors Linked to the Development of Severe Forms of Endometriosis
This study will aim to identify genetic, medical, dietary and environmental factors associated with the development of endometrioma and/or deep infiltrating endometriosis in order to move towards early diagnosis and…
- Trial name
- FEELING (NCT01351051)
- Where
- 7 sites in China, France and 1 more
- Volunteers
- 1,008 people
- Sponsor
- Ipsen