Clinical trials: Deep Endometriosis
Endometriosis
Functional Outcome in Patients That Underwent Laparoscopic Sigmoid and/or Rectum Resection
Questionnaire To assess the functional outcome in patients that underwent laparoscopic sigmoid and/or rectum resection.
- Trial name
- NCT01953250
- Where
- Belgium
- Volunteers
- 143 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Endometriosis
The North-West Inter Regional Female Cohort for Patients With Endometriosis
All women managed for endometriosis are included and followed up through the CIRENDO database. Information is obtained from surgical and histological records and from self-questionnaires completed before surgery.
- Trial name
- CIRENDO (NCT02294825)
- Testing
- various surgical procedures in endometriosis
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Rouen
Endometriosis
IVF Versus Surgery for Endometriosis Related Infertility
The management of endometriosis-related infertility remains controversial. In particular, there is an equipoise for infertile women with endometriotic lesions detected at ultrasound.
- Trial name
- SVIDOE (NCT04743167)
- Testing
- Surgery, IVF
- Where
- 3 sites in Italy
- Volunteers
- 206 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Endometriosis (Diagnosis), Endometriosis
Combining Ultrasound and Biomarkers to Diagnose Superficial Endometriosis
Endometriosis is a benign gynecological disease characterized by uterine-like cells growing outside the uterus, leading to pain, infertility, and inflammation.
- Trial name
- SPGENDO (NCT05523284)
- Testing
- SonoPODography
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Endometriosis, Ovarian Reserve
Impact of Surgery for Deep Posterior Endometriosis on Ovarian Reserve (ENDORO)
Endometriosis is a chronic condition typically affecting women of reproductive age and often responsible for chronic pelvic pain and/or infertility. Its prevalence is estimated at 10% of the female population.
- Trial name
- ENDORO (NCT07469007)
- Testing
- pelvic ultrasound, Anti-Müllerian hormone assay, Questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Endometriosis
Evaluation of New Biomarkers in Stage 3 and 4 Endometriosis
The diagnostic value of Annexin V, sVCAM-1, sICAM-1, vascular endothelial growth factor and Proinflammatory cytokines (TNF-a and interleukin-6) in ovarian endometriosis and deep infiltrating endometriosis, their levels in…
- Trial name
- NCT05312528
- Testing
- endometriosis surgery, other benign condition surgeries
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Deep Endometriosis
Robotic Surgery in the Treatment of Deep Endometriosis: Da Vinci Vs HUGO RAS Comparison
The aim is to clarify whether both surgical approaches represent, equivalently, a good treatment for the management of patients with deep endometriosis who are candidates for surgery, or whether there are any differences between…
- Trial name
- NCT06781398
- Where
- 2 sites in Italy
- Volunteers
- 86 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Ovarian Endometrioma, Endometriosis
Histological Assessment of Tissue Penetration Depth of Argon Beam Coagulation in Ovarian Endometriomas
The goal of this clinical trial is to evaluate the depth of tissue penetration of Argon Beam Coagulation (ABC) during laparoscopic surgery for ovarian endometriomas.
- Trial name
- ENDO-ARGON (NCT07711743)
- Testing
- Argon Plasma Coagulation
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Endometriosis
Functional Outcomes After Nerve Sparing Surgery for Deep Endometriosis
Patients who underwent surgery for deep endometriosis were submitted to procedures aiming at sparing the pelvic autonomic nervous system.
- Trial name
- NCT03353935
- Testing
- Validated questionnaires
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Università degli Studi dell'Insubria
Endometriosis
Physiotherapy of the Pelvic Floor in Women With Deep Infiltrating Endometriosis
The aim of our study is to evaluate the impact of pelvic floor physiotherapy in symptomatic patients affected by deep infiltrating endometriosis, using 3D/4D transperineal ultrasound for evaluation of pelvic floor morphometry…
- Trial name
- endofisio-01 (NCT03572075)
- Testing
- assessment of symptoms at the first medical examination, pelvic floor physiotherapy, standard care protocol
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Deep Infiltrating Endometriosis (DIE), Transrectal Ultrasound
Evaluation of Rectal Infiltration Depth and Length in Bowel Involvement of Deep Infiltrative Endometriosis (DIE) Using Intraoperative Transrectal Ultrasound (TRUS)
we aim to evaluate the success of intraoperative transrectal ultrasound in measuring the depth and extent of bowel involvement in patients preoperatively diagnosed with intestinal endometriosis using transvaginal ultrasound and…
- Conditions
- Deep Infiltrating Endometriosis (DIE), Transrectal Ultrasound, Bowel Endometriosis, Bowel Resection
- Trial name
- DIE IO TRUS (NCT06776536)
- Testing
- Transrectal ultrasound of the bowel endometriosis during operation
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Endometriosis, Endometriosis-related Pain
Intraoperative Sono-assessment In Deep Endometriosis
Deep infiltrating endometriosis (DIE) involving the bowel, particularly the rectosigmoid region, is associated with significant gastrointestinal symptoms and impaired quality of life.
- Conditions
- Endometriosis, Endometriosis-related Pain, Pelvic Pain Syndrome, Endometriosis, Rectum
- Trial name
- INSIDE (NCT07517081)
- Volunteers
- 57 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Endometriosis, Central Sensitisation
Dyspareunia and Central Sensitization
Background: Endometriosis affects 10% of reproductive aged females, and can have a negative impact on sexual quality of life. Endometriosis can cause pelvic pain with deep penetration during intercourse, as well as other sexual…
- Conditions
- Endometriosis, Central Sensitisation, Dyspareunia
- Trial name
- NCT03216330
- Testing
- No Intervention
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- BC Women's Hospital & Health Centre
Endometriosis, Bladder Pain Syndrome
Translational Research in Pelvic Pain
This study aims to better understand the pathways leading to pain in women with two types of pelvic pain condition (endometriosis-associated pain and bladder pain syndrome) and determine whether these pathways can be used to…
- Conditions
- Endometriosis, Bladder Pain Syndrome, Chronic Pain
- Trial name
- TRiPP (NCT04001244)
- Where
- 2 sites in Portugal, United Kingdom
- Volunteers
- 787 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Deep Endometriosis
Efficacy of Double Contrast-enhanced Ultrasound of Pelvic in Preoperative Evaluation of Deep Endometriosis
Endometriosis occurs in about 10-15% of women of childbearing age and is a major cause of infertility and dysmenorrhea. Deep endometriosis is the most serious manifestation of endometriosis, which often affects the quality of…
- Trial name
- NCT05540821
- Testing
- Hysterosalpingo-contrast sonography and sonoPODography
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Shenzhen Second People's Hospital
Endometriosis
MEdical Versus SUrgical Treatments of Rectal Endometriosis
The purpose of this study is to determine whether, in women with deep endometriosis involving the rectum and not intending to get pregnant, continuous hormonal treatment would be followed by better digestive functional outcomes…
- Trial name
- MESURE (NCT01973816)
- Testing
- Triptoreline 11.25 i.v.; Estradiol 0.5% percutaneous gel;, rectal shaving; rectal disc excision; colorectal resection, Cyproterone acetate 50 mg; estradiol 0.5% percutaneous
- Where
- 11 sites in France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Rouen
Visualization of Ureters in Gynecological Surgery, Deep Infiltrative Endometriosis
ICG for Visualization of the Ureters in DIE
Endometriosis is a common condition with an incidence of approximately 10% of all women in the fertile phase. Deep infiltrating endometriosis (DIE) has been shown to be associated with high morbidity.
- Conditions
- Visualization of Ureters in Gynecological Surgery, Deep Infiltrative Endometriosis, ICG (Indocyanine Green), Near Infrared Imaging
- Trial name
- Lavic (NCT05206279)
- Testing
- Ureteral injection of Indocyanine Green Powder (diluted)
- Where
- Switzerland
- Volunteers
- 51 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Endometriosis
TVUS vs MRI Efficacy in Diagnosis of Laparoscopically Managed Patients With DIE
The purpose of the study is to compare the reliability and accuracy of systematic ultrasonographic scanning using International Deep Endometriosis Analysis group approach versus magnetic resonance imaging (MRI) assessment in…
- Trial name
- NCT06821438
- Testing
- Laparoscopy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Endometriosis
Prospective Study of the Outcomes of the Surgical Treatment of Deeply Infiltrating Endometriosis
The aim of this study is to examine the incidence of deeply infiltrating endometriotic lesions among surgically treated endometriosis patients, and examine the impact of endometriosis, and its surgical treatment, on severity of…
- Trial name
- NCT01105897
- Testing
- Endometriosis surgery
- Where
- Finland
- Volunteers
- 201 people
- Sponsor
- PaijatHame Central Hospital
Endometriosis
Effects of Extensive Abdominal Lavage on Postoperative Inflammation Following Full Thickness Excision of Deep Endometriosis
Surgical treatment of deep endometriosis with bowel involvement is widely accepted to require complete excision of all endometriosis also when invading the bowel.
- Trial name
- NCT00930696
- Testing
- Extensive abdominal lavage, Rinsing of the abdomen
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- KU Leuven