Clinical trials: Defibrillation
Ventricular Tachyarrhythmia
NORDIC ICD (Cardioverter Defibrillator Implantation) Trial
The purpose of the NORDIC ICD study is to evaluate whether ICD implantation without intra-operative DF testing is non-inferior to ICD implantation with intra-operative DF testing regarding the efficacy of the first ICD shock for…
- Trial name
- NCT01282918
- Testing
- ICD implantation w/o DF test, ICD implantation with DF test
- Where
- 2 sites in Germany, Sweden
- Volunteers
- 1,077 people
- Sponsor
- Biotronik SE & Co. KG
Heart Failure, Congestive, Ventricular Fibrillation
Safety and Effectiveness of Cardiac Resynchronization Therapy With Defibrillation
The purpose of this study was to determine if cardiac resynchronization therapy when combined with defibrillation is safe and effective in the treatment of symptomatic heart failure.
- Conditions
- Heart Failure, Congestive, Ventricular Fibrillation, Tachycardia, Ventricular
- Trial name
- NCT00387803
- Testing
- Cardiac Resynchronization Therapy with Defibrillation
- Where
- United States
- Volunteers
- 581 people
- Sponsor
- Boston Scientific Corporation
Heart Failure, Congestive, Tachycardia, Ventricular
Right Ventricular Defibrillation Lead Select Site Study
This study will compare single coil right ventricular defibrillation leads for implanted cardioverter/defibrillators (ICDs) in the apical and high septal locations.
- Trial name
- NCT00385749
- Testing
- RV apical vs RV septal defibrillation threshold testing
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Associates in Cardiology, PA
Atrial Fibrillation (AF), Atrial Flutter
Detection of Atrial Fibrillation Through Voice Signal Processing
This study is testing a new technology that listens to a person's voice during short phone calls to help identify heart rhythm problems.
- Trial name
- NCT07212816
- Testing
- Sauti
- Volunteers
- 40 people
- Sponsor
- Vital Audio Inc
Cardiac Arrest
RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems
RACE-CARS is a real-world cluster-randomized trial designed to evaluate a multifaceted community and health systems intervention aimed to improve outcomes of out-of-hospital cardiac arrest.
- Trial name
- NCT04660526
- Testing
- Rapid cardiac arrest recognition that triggers immediate priority EMS/first responder dispatch by 911 operators, Systematic bystander resuscitation instruction by 911 operators, Comprehensive community training of lay people in CPR and AED use.
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Duke University
Atrial Fibrillation
Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus
Evaluating contrast enhanced ECG-gated cardiac CT (CCT) as an alternative to transesophageal echocardiography (TEE) to expedite cardioversion of atrial fibrillation (AF), improve patient care and reduce hospital admissions for AF…
- Trial name
- LACLOT (NCT04223505)
- Testing
- Contrast enhanced ECG-gated cardiac CT (CCT), Transesophageal Echocardiography (TEE)
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Atrial Fibrillation
Use of Fish Oils to Reduce Recurrence of Atrial Fibrillation Following DC Cardioversion
The purpose of this study is to investigate whether fish oil supplements may be beneficial in preventing the recurrence of atrial fibrillation after cardioversion.
- Trial name
- NCT00232219
- Testing
- Fish oil
- Where
- Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Melbourne Health
Persistent Atrial Fibrillation
Evaluation of Two Different Regimens of the Antiarrhythmic Drug Amiodarone to Maintain Normal Sinus Rhythm After Electrical Cardioversion in Patients With Persistent Atrial Fibrillation
--- The goal of this clinical trial is to learn if reduced doses of amiodarone can treat atrial fibrillation (AF) effectively while minimizing toxic side effects in patients with persistent AF after electrical cardioversion.
- Trial name
- PERIVERSION-2 (NCT07273994)
- Testing
- Amiodarone Hydrochloride 200 MG, Amiodarone Hydrochloride 100 MG
- Where
- Spain
- Volunteers
- 312 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Persistent Atrial Fibrillation, Cardiac Arrhythmia
Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF)
The main aim of the research is to investigate whether patients undergoing pulmonary vein isolation with catheter ablation for persistent atrial fibrillation (AF) will have lower rates of AF recurrence than those treated by DC…
- Conditions
- Persistent Atrial Fibrillation, Cardiac Arrhythmia, Catheter Ablation
- Trial name
- ORBICA-AF (NCT06096246)
- Testing
- Pulmonary vein isolation, DC Cardioversion, Implantable loop recorder
- Where
- United Kingdom
- Volunteers
- 208 people
- Sponsor
- Barts & The London NHS Trust
Cardioversion, Atrial Fibrillation
Heart Watch Study: a Pragmatic Randomized Controlled Trial
This will be a prospective multi-center, randomized, controlled trial of 150 patients conducted to assess the impact of individual use of the Apple Watch compared to the Withings Move on patient-reported and clinical outcomes at…
- Trial name
- NCT04468321
- Testing
- Apple Watch, Withings Move
- Where
- 3 sites in United States
- Volunteers
- 105 people
- Sponsor
- Yale University
Atrial Fibrillation, Cardioversion
Risk of Stroke and Silent Cerebrovascular Thromboembolism After Cardioversion of Atrial Fibrillation
Patients with atrial fibrillation undergoing cardioversion will be randomized to undergo transesophageal echocardiography or they will receive warfarin for 3 weeks with an international normalized ratio (INR) value between…
- Conditions
- Atrial Fibrillation, Cardioversion, Cerebrovascular Stroke
- Trial name
- AFTER-CV (NCT01924065)
- Testing
- Cardioversion, Oral Anticoagulant
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Suleyman Demirel University