Clinical trials: Deficiency, Vitamin D
Vitamin D Inadequacy, Vitamin D Deficiency
Clinical Approaches to Correcting Vitamin D Inadequacy and Maintaining Adequacy
Vitamin D is available in two forms, vitamin D2 and vitamin D3. It has previously been assumed that these two forms maintain blood vitamin D equally. However, this may not be the case.
- Trial name
- D2/D3 (NCT00692120)
- Testing
- Cholecalciferol (vitamin D3), Ergocalciferol (vitamin D2)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Diabetes Mellitus, Vitamin D Deficiency
Effect of Vitamin D Supplementation on Hemoglobin A1c
This is a prospective, randomized, non-blinded interventional study that will investigate the effect of a vitamin D supplement on HbA1c in patients with uncontrolled type 2 diabetes mellitus (DM) and vitamin D deficiency.
- Trial name
- NCT01354262
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Ascension Health
Vitamin D Deficiency
Comparing Different Amounts of Vitamin D Supplementation to Preschool Children Living in Northern and Southern Sweden
Vitamin D has a range of biological effects of public health relevance. Vitamin D status is assessed on levels of its metabolite 25-hydroxyvitamin D [25(OH)D], where levels < 50 nmol/L indicate insufficiency.
- Trial name
- Dvisum (NCT01741324)
- Testing
- Vitamin D 25 microg/d, Vitamin D 10 microg/d, No extra vitamin D
- Where
- 2 sites in Sweden
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Umeå University
Major Depression, Vitamin D Deficiency
Effects of Vitamin D Supplementation on Depression and Inflammatory Markers
The current study is designed as a prospective partially randomized patient preference (PRPP) trial and recruit psychiatric outpatients or inpatients.
- Trial name
- NCT04898725
- Testing
- Vitamin D3
- Where
- Taiwan
- Volunteers
- 142 people
- Sponsor
- Mackay Memorial Hospital
Polycystic Ovary Syndrome, Vitamin D Deficiency
The Effects of Vitamin D on Angiogenic Factors in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) affects 5 to 10% of women of reproductive age. It is characterized by a cluster of hyperandrogenism, hyperinsulinemia, menstrual dysfunction, hirsutism and infertility.
- Trial name
- NCT02460380
- Testing
- Vitamin D3
- Volunteers
- 93 people
- Sponsor
- Maimonides Medical Center
Hypovitaminosis D, Cardiovascular Diseases
Effect of vitaminD3 or 25(OH)D3 Fortified Dairy on Vitmain D Status and CVD Risk Markers
This study aims to compare the acute effect of consuming milk and butter fortified with either vitamin D3 or 25 (OH) D3 on serum/plasma vitamin D status in humans.
- Trial name
- NCT02535910
- Testing
- vitamin D3, 25(OH) D3, Control
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Reading
Sleep Disorder, Pregnancy Related
Vitamin D and Sleep Disorders in Pregnancy
Lack of sleep and poor sleep quality in pregnant women are associated with maternal depression and cognitive-sensual irregularities.
- Conditions
- Sleep Disorder, Pregnancy Related, Vitamin D Deficiency
- Trial name
- NCT04918368
- Testing
- Behavioral scales were used
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Hip Arthropathy, Knee Arthropathy
Effect of Vitamin D Status and Repletion on Postoperative Total Joint Arthroplasty Complications
Vitamin D status has been shown to have an effect on post-operative outcomes in total joint arthroplasty. The goal of this study is to determine if pre-operative supplementation and correction of Vitamin D deficiency can reduce…
- Conditions
- Hip Arthropathy, Knee Arthropathy, Vitamin D Deficiency
- Trial name
- NCT04229368
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Brigham and Women's Hospital
Rickets
Ultrasound Imaging and Quantitative Vibro-Acoustic Assessment of Rickets Under the Age of Ten
The goal of this study is to find out if the use of ultrasound pictures of bones can spot changes in the growth areas of children with rickets, a condition that affects how bones harden.
- Trial name
- NCT06385938
- Testing
- Ultrasound with quantitative vibro-acoustic assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Inflammatory Bowel Diseases, Vitamin D Deficiency
Vitamin D Repletion and Maintenance in IBD: How Much and How Often
Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn's disease (CD), are chronic relapsing inflammatory conditions of the gastrointestinal tract.
- Trial name
- NCT03053414
- Testing
- Vitamin D (ergocalciferol and/ or cholecalciferol)
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Vitamin D Deficiency, Periodontitis
25-Hydroxyvitamin D Levels in Patients With Periodontitis (Stage III)
Periodontitis; is an inflammatory disease of tissues characterized by bone destruction around the teeth. Vitamin D plays an important role in several inflammatory diseases by promoting the expression of inflammatory cytokines…
- Trial name
- NCT05343273
- Testing
- taking a blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ataturk University
COVID-19, Vitamin D Deficiency
Vitamin D Supplementation in the Prevention and Mitigation of COVID-19 Infection
The purpose of this study is to evaluate how useful vitamin D supplementation is in reducing the severity of COVID-19 symptoms and the body's inflammatory and infection-fighting response to COVID-19.
- Conditions
- COVID-19, Vitamin D Deficiency, Respiratory Viral Infection
- Trial name
- VitD-COVID19 (NCT04482673)
- Testing
- Daily Vitamin D3, Bolus vitamin D3
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Healthy Humans
Immune and Metabolic Effects of Vitamin D Supplementation in Healthy Humans
In this placebo controlled study the investigators aim to investigate the effect of a 3 month vitamin D supplementation on parameters of the immune, endocrine and metabolic system in healthy women and men. Vitamin D.
- Trial name
- NCT01248442
- Testing
- Cholecalciferol
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Peritoneal Dialysis-associated Peritonitis, Vitamin D Deficiency
Oral Vitamin D Supplementation Prevent Peritoneal Dialysis-related Peritonitis
This is a multicenter randomized, placebo-controlled trial of Vitamin D supplementation in patients on peritoneal dialysis to determine whether oral administration of vitamin D3 after curing an episode of peritonitis could reduce…
- Trial name
- VD-PD (NCT05860270)
- Testing
- Cholecalciferol
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Peking University First Hospital
Vitamin D Deficiency
Interventional Trial of Vitamin D Deficiency in the Patients of General Departments
The purpose of the study is to examine the vitamin D state of elder patients in therapeutic departments and to compere the treatment during the hospitalization with the out-patient treatment.
- Trial name
- NCT00640237
- Testing
- Alpha-D3
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Rambam Health Care Campus
Hypophosphatasia (HPP)
A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)
This study aims to characterize the natural history of patients with severe perinatal or infantile onset HPP.
- Trial name
- NCT01419028
- Where
- 12 sites in United States, Australia and 5 more
- Volunteers
- 48 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Metabolic Bone Disease, Osteopenia
A Study to Assess Metabolic Bone Disease of Prematurity Using an Acoustic Method
The goal of this project is to develop a new noninvasive ultrasound based technique, called vibro-acoustic analysis (VAA), for evaluation of infant bone health with particular application in assessment of bone health in premature…
- Conditions
- Metabolic Bone Disease, Osteopenia, Neonatal Rickets
- Trial name
- NCT04752098
- Testing
- Vibro-acoustic analysis (VAA), based on ultrasound radiation force
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Mayo Clinic
Polycystic Ovary Syndrome, Vitamin D Deficiency/Insufficiency
The Effect of Calcium and Vitamin D Supplements on Metabolic and Hormonal Disturbances in Polycystic Ovary Syndrome Patients
The aim of this study is to investigate the safety and metabolic-hormonal efficiency of supplementation vitamin D deficient/insufficient PCOS women with (calcium +vitamin D + metformin) for 8 weeks compared to (placebo+…
- Trial name
- NCT03792984
- Testing
- Vitamin D3, Calcium Carbonate, Metformin
- Where
- 2 sites in Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Hypovitaminosis D
Importance of Dosing Regimen for the Effect of Vitamin D Supplementation
Vitamin D is a hormone with effects not only on the skeleton, but on most tissues in the body. Lack of vitamin D is associated with cardio-vascular disease (CVD), type 2 diabetes, cancer, infectious and immunological diseases, as…
- Trial name
- NCT03272126
- Testing
- Vitamin D
- Where
- Norway
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Healthy
Defining Vitamin D Insufficiency in School Age Children: A Randomized Placebo Controlled Trial of Vitamin D3
The study objective is to characterize the threshold levels of serum 25-hydroxyvitamin D for the definition of vitamin D insufficiency in 8-14 year old African American and Caucasian children.
- Trial name
- Vitamin D RCT (NCT00732758)
- Testing
- Vitamin D3 1000 IU
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
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