Clinical trials: Deficiency, Vitamin D
Hypophosphatasia
Expanded Access Program for Asfotase Alfa Treatment for Patients With Infantile- or Juvenile-onset Hypophosphatasia (HPP)
This clinical trial is being conducted in Hypophosphatasia, a bone disorder caused by gene mutation(s) resulting in bone defects. These gene mutations cause low levels of an enzyme needed to harden bone.
- Trial name
- NCT02496689
- Testing
- asfotase alfa
- Where
- 5 sites in United States, France
- Sponsor
- Alexion Pharmaceuticals, Inc.
Nutritional Status, Nutrient Deficiency
Adults Nutrition as a Protective or Health-risk Factor
To obtain up-to-date data on nutrient intakes in adults, a national dietary survey - the EU Menu study will be conducted during 12 consecutive months in 2017/2018, providing data on the consumption of foods and enabling the…
- Conditions
- Nutritional Status, Nutrient Deficiency, Micronutrient Deficiency, Vitamin D Deficiency
- Trial name
- NUTRIHEALTH (NCT03284840)
- Testing
- Assessement of nutritional status, Thyroid size
- Where
- 3 sites in Slovenia
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Back Pain, Hypovitaminosis D
Vitamin D Treatment to Patients Suffering From Chronic Pain and Vitamin D Hypovitaminosis
The objective of this study is to check whether vitamin D will lead to a decrease in pain intensity compare to placebo, in patients suffering from chronic pain.
- Trial name
- NCT01023490
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Vitamin D Deficiency, Neuromuscular Block
D Vitamin Effects on Neuromuscular Blocker Reverse Time
Background/aim: Investigators aimed to investigate the effect of D vitamin levels on Sugammadex and Neostigmine reverse durations in the study.
- Conditions
- Vitamin D Deficiency, Neuromuscular Block, Neuromuscular Block Problem
- Trial name
- NCT03734250
- Volunteers
- 84 people
- Sponsor
- Duzce University
Polycystic Ovary Syndrome, Vitamin D Deficiency
The Effects of Vitamin D on Angiogenic Factors in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) affects 5 to 10% of women of reproductive age. It is characterized by a cluster of hyperandrogenism, hyperinsulinemia, menstrual dysfunction, hirsutism and infertility.
- Trial name
- NCT02460380
- Testing
- Vitamin D3
- Volunteers
- 93 people
- Sponsor
- Maimonides Medical Center
Iron Deficiency, Anemia; Deficiency, Nutritional, With Poor Iron Absorption
A Study to Investigate the Effect of Vitamin D3 Supplementation on Iron Status in Iron Deficient Women
Iron is one of the most vital elements in humans as it plays a role in physiological functions such as transferring and storing oxygen, transporting electrons and catalysing numerous reactions, from oxidative metabolism to…
- Conditions
- Iron Deficiency, Anemia; Deficiency, Nutritional, With Poor Iron Absorption, Vitamin D Deficiency
- Trial name
- NCT02714361
- Testing
- Vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chester
Ulcerative Colitis, Vitamin D Deficiency
Effect of Vitamin D Supplementation on Vedolizumab Response in Patients With Ulcerative Colitis
It is uncertain whether vitD3 supplementation is beneficial for the remission of ulcerative colitis (UC). The effects of vitD3 supplements on the efficacy of vidrecizumab in Chinese UC patients were retrospectively analyzed.
- Conditions
- Ulcerative Colitis, Vitamin D Deficiency, Vitamin D Supplement
- Trial name
- NCT05649462
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
HIV Infection
Vitamin D Absorption in HIV Infected Young Adults Being Treated With Tenofovir Containing cART
This is a 48 week randomized double-blind, placebo-controlled prospective cohort study of adolescents and young adults with HIV infection in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) who are…
- Trial name
- NCT01751646
- Testing
- Vitamin D3 50,000 IU
- Where
- 17 sites in United States, Puerto Rico
- Volunteers
- 214 people
- Sponsor
- University of North Carolina, Chapel Hill
Vitamin D Deficiency, Musculoskeletal Diseases
Vitamin D in School Children
The primary purpose of this study it to investigate total circulating 25-hydroxyvitamin D (25(OH)D) in school children (aged 4-11years) in Northern Ireland; thereby establishing the prevalence of vitamin D status (deficiency…
- Conditions
- Vitamin D Deficiency, Musculoskeletal Diseases, Cognitive Delay, Mild
- Trial name
- DVinCHI (NCT05018988)
- Testing
- Oral vitamin D spray
- Where
- United Kingdom
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Vitamin D Deficiency, Malnutrition
Optimizing Treatment Programs for Chronic Kidney Disease-mineral and Bone Disorder and Malnutrition
Multi-center, prospective, randomized, controlled study to verify the clinical effectiveness of K / DOQI guidelines. The efficiency and safety of Vitamin D2 and low protein diet treatment for prevention and treatment of CKD-MBD…
- Trial name
- NCT02005302
- Testing
- 1,25(OH)2 Vitamin D3, Vitamin D2, low protein diet
- Where
- 5 sites in China
- Volunteers
- 600 people
- Sponsor
- Wenhu Liu
Chronic Kidney Disease Mineral and Bone Disorder, Hypertension
Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD
The overall objective of this pilot randomized clinical trial is to determine whether low-dose Colchicine (LoDoCo) improves vascular disease including vascular calcification, peripheral arterial disease (PAD), and chronic kidney…
- Conditions
- Chronic Kidney Disease Mineral and Bone Disorder, Hypertension, Diabetes, Dyslipidemia
- Trial name
- RESOLVE-CKD (NCT07654231)
- Testing
- Low-dose Colchicine at 0.5mg daily, Usual Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
Vitamin D Deficiency
Vitamin D Among Young Adults: an Intervention Study Using a Mobile 'App'.
The purpose of this study is to examine whether a behavioural intervention changes attitudes, knowledge, intake or blood levels of vitamin D in young adults.
- Trial name
- NCT02118129
- Testing
- an educational video, wait listed
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Vitamin D Deficiency
Vitamin D Status in Hemodialysis Transplant Candidates and Living Donors
Vitamin D, beyond its classical role in calcium and phosphate metabolism, is recognized as an important regulator of immune function and inflammation.
- Trial name
- NCT07409623
- Testing
- VITAMIN D LEVEL
- Where
- Iran
- Volunteers
- 552 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Osteoporosis, Aging
Vitamin D Supplementation in Older Women
The purpose of this study is to examine the effects of several doses of vitamin D on hormones related to bone, calcium absorption, bone density and muscle strength.
- Trial name
- VIDOS (NCT00472823)
- Testing
- Vitamin D3, Calcium Citrate (Citracal)
- Where
- United States
- Volunteers
- 273 people
- Sponsor
- Creighton University
Healthy
Assessment of the Efficacy of Vitamin D-fortified Bread in Healthy Adults
The aim of this study is to evaluate the efficacy of daily intake of fortified bread with vitamin D on serum 25-hydroxyvitamin D level, glycemic and lipidemic status in healthy subjects compared to vitamin D supplement.
- Trial name
- NCT02516254
- Testing
- fortified bread, supplement
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Nutrition and Food Technology Institute
Fracture Healing, Vitamin D3
The Vitamin K2 and D3 Intervention Trial in Children and Adolescents With the Low-energy Fractures
a prospective, three- month, randomized, double-blind, placebo-controlled, intervention trial (RDBPC), investigating the effect of vitamin K2 (menaquinone-7) and vitamin D3 on the healing process of low-energy bone fractures in…
- Conditions
- Fracture Healing, Vitamin D3, Deficiency of Vitamin K2
- Trial name
- NCT03871322
- Testing
- Vitamin D and K2 supplementation, Vitamin D supplementation
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Idiopathic Infantile Hypercalcemia - Severe Form
Vitamin D Analog in Vitamin D 24-hydroxylase Deficiency
Preclinical evaluation of a vitamin D analog for the treatment of vitamin D 24-hydroxylase using fibroblast from patients with CYP24A1 mutation.
- Trial name
- VaraD-Cell (NCT04987073)
- Testing
- skin biopsy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Chronic Kidney Disease (Stage 3-4), Chronic Kidney Disease Mineral and Bone Disorder
Phosphate Assessment in Chronic Kidney Disease Patients Study
The proposed pilot feeding study aims to explore novel pathways in phosphate metabolism and identify new biomarkers, as well as to develop a compound index for assessing phosphate overload with high validity and reliability.
- Trial name
- PACK (NCT07368946)
- Testing
- Dietary Phosphorus Intake
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Vitamin D Deficiency
A Prospective, Multi-center Study to Evaluate the Efficacy and Safety of Vitamin D3 B.O.N. Intramuscular Injection in Adults With Vitamin D Deficiency
To compare the efficacy of Vitamin D3 B.O.N. Intramuscular Injection within 12 weeks with that of placebo in adults with Vitamin D Deficiency.
- Trial name
- NCT02443246
- Testing
- Vitamin D3 B.O.N. Injection (cholecalciferol 200,000IU)
- Volunteers
- 84 people
- Sponsor
- Kwang Dong Pharmaceutical co., ltd.
Serum 25-hydroxyvitamin D Concentrations (25OHD)
The BreaD Study - Bio-availability of D2 Vitamin Present in Bread
Vitamin D3 is synthesized in skin exposed to ultraviolet-B-irradiation of sunlight. However, in Northern Europe, including Finland, exposure to sunlight is limited or non-existent in winter.
- Trial name
- BreaD_ODIN (NCT02525003)
- Testing
- Vitamin D2, Vitamin D3, Vitamin D2 fortified bread
- Where
- Finland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
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