Clinical trials: Deficiency, Vitamin D
Hypophosphatasia
Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)
This clinical trial studied the long term safety and efficacy of asfotase alfa in infants and young children with infantile onset HPP who completed study ENB-002-08 (NCT00744042).
- Trial name
- NCT01205152
- Testing
- asfotase alfa
- Where
- 8 sites in United States, United Arab Emirates and 1 more
- Volunteers
- 10 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Vitamin d Deficiency
Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Major Surgical Procedures.
Vitamin D (Vitamin D) deficiency is very common. We recently showed that 97% of 204 patients admitted to Truman Medical Center were Vitamin D deficient (<30 ng/ml).
- Trial name
- NCT02138591
- Testing
- Blood draw pre-operatively, Blood draw post-operative Day 1, Blood draw post-operative Day 2
- Where
- United States
- Sponsor
- University of Missouri, Kansas City
Vitamin D Deficiency
Randomized Trial of Enteral Vitamin D Supplementation in Infants < 28 Weeks Gestational Age or <1000 Grams Birth Weight
The objective of the study is to compare supplementation with vitamin D at 800 IU/day to usual care for the first 28 days after birth with respect to 25 (OH) vitamin D levels and indicators of likely or plausible effects of…
- Trial name
- NCT05694689
- Testing
- 800 IU/day vitamin D supplementation with feedings in the first 28 days after birth, Usual Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center, Houston
Vitamin D Deficiency, Nasal Polyposis
Effect of Vitamin d Deficiency in Chronic Rhinosinusitis With Nasal Polyposis
Aim of the work 1. To determine if chronic rhinosinusitis with nasal polyps' (CRSwNP) populations are vitamin D deficient. 2. To determine the possible anti-inflammatory effect of vitamin D supplementation (clinically \&…
- Trial name
- NCT04529668
- Testing
- vitamin D supplementation, usual therapy for nasal polyposis
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Vitamin D Deficiency
Vitamin D Status and Its Influencing Factors in Zhejiang Province: A Multicenter Cross-Sectional Study
Vitamin D deficiency is a global public health problem, with an estimated 1 billion people affected worldwide, and large-scale systematic data for Zhejiang Province remain scarce.
- Trial name
- NCT07866391
- Where
- 2 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Vitamin D Deficiency, Cystic Fibrosis
Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patients With CF
Cystic fibrosis (CF) is an autosomal recessive disease caused by alterations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, characterized by multisystemic alterations, mainly in the lung, intestine…
- Conditions
- Vitamin D Deficiency, Cystic Fibrosis, Bone Density, Low, Inflammation Chronic
- Trial name
- NCT05276960
- Testing
- Cholecalciferol Pill
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Covid19, Vitamin D Deficiency
High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study
The world is currently facing a pandemic with the coronavirus (SARS-CoV-2) which leads to the disease of COVID-19. Risk factors for a poor outcome of COVID-19 have so far been identified as older age and co-morbidity including…
- Conditions
- Covid19, Vitamin D Deficiency, Corona Virus Infection, ARDS
- Trial name
- VitCov (NCT04525820)
- Testing
- Single high dose vitamin D, Treatment as usual vitamin D
- Where
- 2 sites in Switzerland
- Volunteers
- 80 people
- Sponsor
- Prof. Dr. Jörg Leuppi
Lung Diseases, Interstitial, Vitamin D Deficiency
Vitamin D Deficiency and Effect of Its Supplementation on Interstitial Lung Diseases(ILD).
This study evaluates serum level of Vitamin D in Interstitial Lung Diseases in patients with Interstitial Lung Diseases other than connective tissue diseases associated-Interstitial Lung Diseases and effects of its…
- Trial name
- ILD (NCT04100226)
- Testing
- Vitamin D3 (1.25 (OH)2 cholecalciferol)
- Where
- Egypt
- Volunteers
- 104 people
- Sponsor
- Cairo University
PCOS
Correction of Vitamin D Deficiency and Its Effect on Ovulation Induction in Women With PCOS (VIDEO): A Feasibility RCT
Recently, a special emphasis has recently been directed to the potential role of vitamin D and some regulatory peptides (e.g. adipokines and follistatin) and their associated metabolic roles and genetic factors in the development…
- Trial name
- PCOSD (NCT02656121)
- Testing
- Vitamin D, Ovulatory Agent
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Vitamin D Deficiency
Genetic, Dietary and Environmental Influences on Vitamin D Metabolism
Determine differences in serum vitamin D metabolism by genetic ancestry.
- Trial name
- NCT02590614
- Testing
- 800 IU Vitamin D
- Where
- United States
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Age-related Macular Degeneration, Vitamin D Deficiency
Omega 3 and Vitamin D Dosage in a Population With Moderate to High Risk of AMD
Objectives: The investigators conducted a prospective study in Belgium with the objective to determine the proportion of subjects identified at moderate-to-high risk for AMD, based on the STARS® questionnaire, in need of…
- Trial name
- OVID-AMD (NCT04482465)
- Testing
- blood sample
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Vitamin D Deficiency
Effect of Vitamin d and Omega 3 on Osteocalcin
Assessing the combined effect of omega-3 fatty acid and vitamin D 3 on plasma osteocalcin levels
- Trial name
- NCT04005612
- Testing
- vitamin D3, omega-3 fatty acid, vitamin D3 and omega-3 fatty acid
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Vitamin D Deficiency, Sarcopenia
The Effectiveness of Vitamin D Supplementation in Patients With End-stage Knee Osteoarthritis
Osteoarthritis (OA) knee is one of the commonest chronic degenerative conditions. It causes disability in elderlies due to pain and stiffness.
- Conditions
- Vitamin D Deficiency, Sarcopenia, Knee Osteoarthritis
- Trial name
- NCT05981534
- Testing
- Vitamin D
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- Chinese University of Hong Kong
Vitamin D Deficiency, End Stage Renal Disease
A Study of Fixed Dose Versus Serum Level-Based Titration Regimen of Vitamin D Supplementation in Dialysis Patients
Vitamin D insufficiency, defined as serum 25-hydroxyvitamin (OH) D level less than 30 ng/ml, is highly prevalent not only in the general population but also in chronic kidney disease (CKD) population.
- Trial name
- NCT05434377
- Testing
- ergocalciferol supplementation, dialysis techniques, sunlight exposure time
- Where
- Thailand
- Volunteers
- 78 people
- Sponsor
- Chulalongkorn University
Hypovitaminosis D
Impact of Hypovitaminosis D on Bone Disease in HIV Infected Patients
To determine the prevalence of hypovitaminosis D in HIV infected patients, and the consequences on secondary hyperparathyroidism, and bone mineral density (BMD).
- Trial name
- PuraVIHta (NCT02351284)
- Testing
- Measurement
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Jose L. Casado
Vitamin D Deficiency
Vitamin D and Its Affect on Growth Rates and Bone Mineral Density Until Age 5
Abstract Background: Vitamin D affects a wide variety of functions in the body including regulation of calcium, phosphorus, and bone metabolism.
- Trial name
- VitD (NCT01419821)
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Chronic Kidney Diseases, Deficiency, Vitamin D
Drug Metabolizing Enzyme and Transporter Function in Chronic Kidney Disease
This study investigates the effect of vitamin D deficiency on drug metabolism and transport in patients with chronic kidney disease (CKD) and in healthy controls.
- Trial name
- NCT02360644
- Testing
- Cholecalciferol
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vitamin D Deficiency, Stress Fracture
Vitamin D3 Supplementation and Stress Fracture Occurrence in High-Risk Collegiate Athletes
The main objective of this study is to find a correlation between vitamin D deficiency and stress fracture occurrences in athletes who participate in high-risk activities.
- Conditions
- Vitamin D Deficiency, Stress Fracture, Athletic Injuries, Orthopedic Disorder
- Trial name
- NCT03395171
- Testing
- Cholecalciferol (Vitamin D3)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Midlands
Vitamin D Deficiency
The Effect of Vitamin D3 Therapy in Post Menopausal Women and Assessment of Changes in Bone Mineral Density After Orally Vitamin D3 Administration
a study design based on vitamin D deficiency in postmenopausal women with low bone density. pre-test for BMD will be done then vitamin D oral supplements will be provided for the period of 3 months.
- Trial name
- NCT05389943
- Testing
- Oral administration of vitamin D3, Vitamin D3 50000 UNT Oral Capsule, milk, Dietary and life style modifications.
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sargodha
Vitamin D Deficiency, Chronic Pain Syndrome
The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain
Vitamin D3 is produced in the skin following exposure to UVB light from the sun or artificial sources, and occurs naturally in a small range of foods.More recently, several reports underlined the impact of vitamin D on the…
- Conditions
- Vitamin D Deficiency, Chronic Pain Syndrome, Inflammatory Response
- Trial name
- NCT01417923
- Testing
- vitamin D
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Meir Medical Center
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