Clinical trials: Deformity of Limb
Genu Varum, Genu Valgus
IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms
While various complex pathologies of the developmental age, such as Infantile Cerebral Palsy or Neuromuscular Diseases, are notoriously considered causes of alteration of locomotor development, it is scarcely known whether…
- Conditions
- Genu Varum, Genu Valgus, Flat Feet, Cavus Foot
- Trial name
- MOTOR-CHILD (NCT05763901)
- Testing
- Clinical tests and motor control evaluation using Inertial Measurement Units
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Istituto Ortopedico Rizzoli
Duchenne Muscular Dystrophy, Muscle Strength
Effect of Muscle Strength on Hamstring Flexibility in Children With Duchenne Muscular Dystrophy
Investigator researched that the effect of trunk and lower extremity muscle strength on hamstring flexibility in children with Duchenne Muscular Dystrophy.
- Conditions
- Duchenne Muscular Dystrophy, Muscle Strength, Lower Extremity, Hamstring Contractures
- Trial name
- NCT03589573
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Cerebral Palsy, Muscle Spasticity
Dysport® Pediatric Lower Limb Spasticity Follow-on Study
The purpose of this research study was to determine the long term safety and efficacy of repeated treatments with Dysport® used in the treatment of lower limb spasticity in children with dynamic equinus foot deformity due to…
- Conditions
- Cerebral Palsy, Muscle Spasticity, Children
- Trial name
- NCT01251380
- Testing
- Botulinum toxin type A
- Where
- 27 sites in United States, Chile and 4 more
- Volunteers
- 216 people
- Sponsor
- Ipsen
Adolescent, Foot Posture Index Score
Relationship Between Foot Posture, Toe Flexor Strength, and Balance in Adolescents
The foot plays a critical role in movement and postural control, with toe flexor strength linked to gait, performance, and stability. While these relationships are well studied in adults, evidence in adolescents is limited.
- Conditions
- Adolescent, Foot Posture Index Score, Toe Flexor Strength, Flat Foot Acquired Bilateral (Pes Planus)
- Trial name
- NCT07132424
- Testing
- Assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Kültür University
Deformity Knee, Deformity of Limb
Proximal Tibial Osteotomy Osteoclasis In Infantile Genu-Varum
Genu-varum is a common problem encountered in pediatric orthopedic. Correction of pathological deformity is mandatory to ensure normal load transfer through the knee.
- Trial name
- NCT04752995
- Testing
- osteotomy
- Volunteers
- 70 people
- Sponsor
- Tanta University
Achilles Tendinopathy, Flatfoot
Orthotics and Achilles Load in Runners
Compare Customized arch support orthoses (CASO) and orthotic heel lift (HL) on the effect of ATL in recreational runners with pronated feet.
- Conditions
- Achilles Tendinopathy, Flatfoot, Sports Injury
- Trial name
- NCT04003870
- Testing
- CASO, HL
- Where
- Hong Kong
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- North District Hospital
Pes Planus, Flat Foot
Effects on Pes Planus Exercise Training Mixed With Play on Pre-school Children
The study was planned to assess effects on pes planus and femoral anteversion angle of exercise training mixed with play on pre-school children.
- Conditions
- Pes Planus, Flat Foot, Femoral Anteversion
- Trial name
- NCT03151538
- Testing
- Exercise Training Mixed With Play, Controlled
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Burcu Talu
Lower Limb Deformity
Clinical-MRI Evaluation in Patients Undergoing Subtalar Arthrorisis With Reabsorbable Endorthesis Implant in PLLA
From the archives of the IRCCS Rizzoli Orthopedic Institute, all cases of arthrorrhesis of the subtalar joint with a reabsorbable endorthotic implant in PLLA will be retrieved.
- Trial name
- CS-RM (NCT06525532)
- Testing
- follow up
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Istituto Ortopedico Rizzoli
Foot Deformities, Pes Planus
The Relationship of the Medial Longitudinal Arch Height With Clinical Features of Knee Osteoarthritis
The goal of this observational study is to investigate the relationships between the medial longitudinal arch (MLA) height of the foot and clinical and radiological characteristics of knee osteoarthritis in adult patients 50 aged…
- Conditions
- Foot Deformities, Pes Planus, Pes Cavus, Knee Osteoarthritis
- Trial name
- NCT05656014
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gazi University
Patellofemoral Joint, Flatfoot
Effect of Foot Orthoses on Kneecap Position in Adults With Flexible Flatfoot
This study will look at whether correcting a flat foot position with foot orthoses, also called shoe inserts, can change the position of the kneecap during standing.
- Trial name
- NCT07678840
- Testing
- Foot Orthoses
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Regionshospital Nordjylland
Cystic Fibrosis, Muscle Strength
Muscle Strength, Functional Capacity, Respiratory Function and Quality Of Life In Cystic Fibrosis Patients
This study was designed to investigate the relationship between upper extremity muscle strength and endurance, functional capacity, and quality of life child and adolescent with cystic fibrosis
- Conditions
- Cystic Fibrosis, Muscle Strength, Pulmonary Function, Functional Capacity
- Trial name
- NCT04734743
- Testing
- cystic fibrosis
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cagtay Maden
Periodontitis, Obesity
EVALUATION of GINGIVAL CREVICULAR FLUID and SERUM ASPROSIN LEVELS in OBESE and NORMAL-WEIGHT INDIVIDUALS with PERIODONTITIS
Obesity and periodontitis are chronic inflammatory diseases that share common pathological mechanisms. Asprosin, a novel adipokine discovered in 2016, has not been extensively studied in relation to periodontal tissues.
- Trial name
- NCT06879951
- Testing
- Participants are not assigned an intervention as part of the study.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Coronary Artery Disease, Proteus Syndrome
Informed Consent for Whole Genome Sequencing: Ideals and Norms Referenced by Early Participants
Since 2007, the cost of sequencing a diploid human genome has fallen dramatically, from approximately $70 million to $20,000. As affordable sequencing platforms become more widely available, the advancement of biomedical science…
- Conditions
- Coronary Artery Disease, Proteus Syndrome, Coffin - Sins Syndrome, Familial Isolated Hyperparathyroidism
- Trial name
- NCT01369953
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Flatfoot
Investigation of Inter-rater and Test-retest Reliability of Y Balance Test in Individuals With Pes Planus
Pes Planus is characterized by the descent of the medial longitudinal arch, eversion of the hindfoot, and dorsiflexion and abduction of the midfoot.
- Trial name
- NCT05616637
- Testing
- Navicular Drop Test, Lower Extremity Length Measurement, Y Balance Test
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Istanbul Gelisim University
Cancer
Study of Lenvatinib in Patients With Advanced Cancer and Aberrations in FGF/FGFR Signaling
This is a two center, open label, non-randomized Phase II study of lenvatinib in adult subjects with recurrent or refractory advanced cancers with aberration(s) in FGF/FGFR signaling.
- Trial name
- NCT02846766
- Testing
- Lenvatinib
- Where
- 2 sites in United States
- Sponsor
- Teresa Helsten, MD
Muscular Dystrophies, Duchenne Muscular Dystrophy
Safety Study of Transvenous Limb Perfusion in Human Muscular Dystrophy
Muscular dystrophies are inherited disorders in which the skeletal and heart muscles become progressively weaker, sometimes leading to permanent disability.
- Conditions
- Muscular Dystrophies, Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, Limb-Girdle Muscular Dystrophy
- Trial name
- NCT00873782
- Testing
- Retrograde high pressure transvenous perfusion with normal saline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of North Carolina, Chapel Hill
Amputation, Dysmelia
Physical Activity and Sports for People With Special Needs
Purpose of this study was to assess the balance level of highly qualified amputee football players in relation to their sports level, training experience, position on the pitch, as well as the type of amputation/dysfunction and…
- Conditions
- Amputation, Dysmelia, Leg; Deformity, Congenital
- Trial name
- NCT05778799
- Testing
- Balance test
- Where
- Poland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Atopic Dermatitis
Safety and Efficacy Study of ImCOOH Cream in Patients Suffering From Moderate Atopic Dermatitis
Atopic dermatitis is one of the most common skin diseases, with a lifetime prevalence of up to 20%, and an increasing number of cases.
- Trial name
- NCT00583895
- Testing
- 10% ImCOOH cream
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Valletta Health B.V.
Amputation Stumps, Amputees
Moisture Management Liner Effectiveness Study
The comfort and fit of the residual limb within a prosthetic socket are of primary concern for many amputees. The residual limb is typically covered by non-breathable and non- thermally conductive materials that can create a warm…
- Conditions
- Amputation Stumps, Amputees, Amputation, Lower Limb Deformities, Congenital
- Trial name
- NCT04427007
- Testing
- Moisture Management Liner, Control Liner
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Cerebral Palsy, Stroke
Reliability of the Melbourne Assessment
The aim of the study is to investigate the reliability of the Melbourne Assessment.
- Conditions
- Cerebral Palsy, Stroke, Traumatic Brain Injury, Meningomyelocele
- Trial name
- NCT02595411
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Children's Hospital, Zurich