Clinical trials: Degenerative Arthritis of Hip
Osteoarthritis of the Knee, Osteoarthritis of the Hip
Cardiovascular And Metabolic Risk After Arthroplasty
Osteoarthritis is a chronic joint disease that lacks curative therapy. Epidemiological studies show increase in the burden of disease. Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis.
- Conditions
- Osteoarthritis of the Knee, Osteoarthritis of the Hip, Cardiovascular Diseases, Metabolic Syndrome
- Trial name
- CAMERA (NCT06211465)
- Testing
- Total joint arthroplasty
- Where
- Estonia
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Anesthesia, Hip Osteoarthritis
The Assessments of the Postoperative Recovery on Elderly Patients Received General Anesthesia or Peripheral Nerve Blocks
Postoperative recovery is always worrisome to the elder patients undergoing Total Hip Replacement (THR). Peripheral Nerve Blocks (PNBs), lumbar plexus block combined with sciatic nerve blocks, may be alterative anaesthesia style…
- Trial name
- NCT01782612
- Testing
- Multimodal analgesic techniques, Total uni-Hip Replacement
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Junle Liu
Joint Disease, Osteoarthritis
Radiostereometric Analysis (RSA) of the PROFEMUR® Preserve Classic Femoral Components
MicroPort Orthopedics (MPO) is conducting this study to investigate the primary stability of its PROFEMUR® Preserve Femoral Components using radiostereometric analysis (RSA).
- Trial name
- TOPAZ (NCT02668211)
- Testing
- PROFEMUR Preserve Classic Femoral Components
- Where
- Canada
- Sponsor
- MicroPort Orthopedics Inc.
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Osteoarthritis
A Study to Assess Etoricoxib Versus Diclofenac in Chinese Patients With Osteoarthritis of the Knee or Hip (0663-080)(COMPLETED)
A Study to Assess Etoricoxib versus Diclofenac in Chinese Patients with Osteoarthritis of the Knee or Hip
- Trial name
- NCT00140972
- Testing
- MK0663; etoricoxib / Duration of Treatment:4 Weeks, Comparator: diclofenac sodium tablet 75 mg / Duration of Treatment:4 Weeks
- Volunteers
- 160 people
- Sponsor
- Organon and Co
Osteoarthritis
Effect of Exercise as Non-surgical Treatments on Time to Total Hip Replacement Surgery
The aim of this trial is to test the hypothesis that patients with severe hip osteoarthritis postpone time to hip replacement surgery following participation in a patient education and supervised exercise program when compared to…
- Trial name
- HipSPORT (NCT01697241)
- Testing
- Supervised exercise, Patient education
- Where
- 2 sites in Denmark
- Volunteers
- 110 people
- Sponsor
- University of Southern Denmark
Avascular Necrosis of Femoral Head, Degenerative Arthritis of Hip
Rotational Thromboelastography Study in Tranexamic Acid and Colloid Infusion
Colloid solution is generally used to maintain intravascular volume. It is reported to impair blood coagulation in vivo and in vitro more than crystalloid does by prolonging coagulation time and decreasing clot strength.
- Trial name
- NCT02146456
- Testing
- Tranexamic Acid
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Bundang Hospital
Osteoarthritis, Hip
Effect of Local Infiltration Anesthesia With Ropivacaine on Pain After Primary Total Hip Arthroplasty
Background: The Local infiltration analgesic (LIA) technique has been widely used to reduce opioid requirements and improve the patient's mobilization after total hip arthroplasty (THA).
- Trial name
- NCT02359136
- Testing
- local infiltration anesthesia using Ropivacaine and Epinephrine, local infiltration anesthesia using saline, Multimodal analgesic regimen
- Where
- Norway
- Volunteers
- 116 people
- Sponsor
- St. Olavs Hospital
Chronic Pain, Osteoarthritis, Hip
Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee
The purpose of this study is to compare the long-term joint safety and efficacy (pain relief) of the investigational study drug, tanezumab compared to non-steroidal anti inflammatory drugs (NSAIDs) in subjects with osteoarthritis…
- Conditions
- Chronic Pain, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT02528188
- Testing
- NSAID, Tanezumab 2.5 mg, Tanezumab 5 mg
- Where
- 507 sites in United States, Australia and 16 more
- Volunteers
- 3,021 people
- Sponsor
- Pfizer
Osteoarthritis
Effect of Structured Info and Adapted Exercise in OA
Physical activity level is measured at baseline and after 3 and 12 months after structured information and individually adapted exercise for patients with osteoarthritis in hip or knee.
- Trial name
- NCT02022566
- Testing
- A supported self management of osteoarthritis program
- Where
- Sweden
- Volunteers
- 317 people
- Sponsor
- Lund University
Osteoarthritis, Hip
Group Exercise After Hip Replacement Surgery
The purpose of this study is to determine which group exercise one should choose when hip osteoarthritis patients have undergone hip replacement surgery.
- Trial name
- NCT01253798
- Testing
- Group training
- Where
- Norway
- Volunteers
- 19 people
- Sponsor
- Norwegian University of Science and Technology
Osteoarthritis, Knee / Osteoarthritis, Hip
Efficacy and Safety of MT-5547 in Patients With Osteoarthritis Accompanied by Moderate to Severe Pain
The objective of this study is to verify the superiority of 16 weeks of MT-5547 treatment to placebo, as evidenced by the WOMAC pain score (the efficacy outcome measure), in patients with osteoarthritis of the knee or hip.
- Trial name
- NCT03245008
- Testing
- MT-5547
- Where
- 27 sites in Japan
- Volunteers
- 626 people
- Sponsor
- Tanabe Pharma Corporation
Osteoarthritis, Arthritis
A Multi-centre, Prospective Surveillance to Assess Mid-term Performance of the Mpact Cup
This is a multi-centre, prospective post marketing surveillance study to assess mid-term performance of the Mpact cup in subjects requiring primary total hip arthroplasty.
- Conditions
- Osteoarthritis, Arthritis, Avascular Necrosis, Fracture of the Femoral Neck or Head
- Trial name
- NCT02196818
- Testing
- Mpact Acetabular Shell
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
Hip Osteoarthritis
The Effectiveness of Client-Centered Intervention inTotal Hip Arthroplasty
The current study was conducted to effectiveness of the Client-centered (CC) intervention after Total Hip Arthroplasty (TKA). The current study was planned to examine the impact of the CC intervention on quality of life…
- Trial name
- NCT06070220
- Testing
- traditional occupational therapy intervention and client-centered intervention, Traditional occupational therapy intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Osteoarthritis, Hyperthyroidism
Povidone Iodine Irrıgation at Hip-Knee Arthroplasty
Povidone iodine (PI) solution is an antimicrobial solution that can be used at hip and knee arthroplasty cases. It contains iodine that may be absorbed by the body.
- Conditions
- Osteoarthritis, Hyperthyroidism, Iodine Toxicity
- Trial name
- NCT05599841
- Testing
- PI solution, Saline Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Knee Osteoarthritis, Knee Disease
ESPB vs FICB for Pain Management Following Total Hip Prosthesis Surgery
Hip arthroplasty surgery is frequently performed on elderly patients in the community and it is associated with long-term postoperative hospital stays and high mortality.
- Conditions
- Knee Osteoarthritis, Knee Disease, Knee Arthritis
- Trial name
- NCT05621161
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mursel Ekinci
Hip Osteoarthritis
Effectiveness of Total Hip Arthroplasty for Patients With Osteoarthritis, a Target Trial Emulation Study
The aim of this study is to assess the effect of total hip arthroplasty on hip disability and pain compared to non-surgery in patients with hip osteoarthritis, using target trial emulation to emulate a randomized controlled trial.
- Trial name
- EAGLE (NCT06263569)
- Testing
- Total hip arthroplasty
- Where
- Netherlands
- Volunteers
- 156 people
- Sponsor
- JointResearch
Hip Osteoarthritis
Comparison of Two Hydroxy-apatite Coated Hip Stems
In this study, the investigators propose to randomize 80 subjects to receive either the Avenir cementless hip stem or a competing, HA-coated hip stem (Corail, DePuy-Synthes) and follow these patients for a period of 2 years…
- Trial name
- NCT03577522
- Testing
- Avenir cementless hip stem, Corail HA-coated hip stem
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Osteoarthritis, Knee, Osteoarthritis, Hip
Effects of a Structured Digital Osteoarthritis Self-management Program After 6 Months of Adherence
This is a study based on a cohort in a register of patients enrolled in a digital osteoarthritis self-management program, Joint Academy.
- Trial name
- NCT04049318
- Testing
- Education+ exercise (delivered digitally)
- Where
- Sweden
- Volunteers
- 1,709 people
- Sponsor
- Lund University
Hip Osteoarthritis
Hip Arthroscopy Versus Total Hip Arthroplasty RCT
The aim of the proposed study is to perform a comparative pilot, randomized controlled trial of hip arthroscopy versus definitive total hip arthroplasty (THA) for the treatment of early hip osteoarthritis (Tönnis Grade 1-2) in…
- Trial name
- NCT04166227
- Testing
- Hip Arthroscopy, Total Hip Arthroplasty
- Where
- 2 sites in Canada
- Volunteers
- 42 people
- Sponsor
- Western University, Canada