Clinical trials: Degenerative Joint Disease
Knee Osteoarthritis, Osteoarthritis, Knee
Autologous Conditioned Serum: Functional and Clinical Results
The purpose of this study was to investigate the potential ability of autologous conditioned serum (ACS) to decrease the pain and improve the joint functionality in patients affected by knee osteoarthritis (OA).
- Conditions
- Knee Osteoarthritis, Osteoarthritis, Knee, Cartilage Degeneration
- Trial name
- NCT03850080
- Testing
- Autologous Conditioned Serum
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Ospedale San Raffaele
Osteoarthritis
CMC (Carpometacarpal) OA (Osteoarthritis) Thumb Splint Study
Osteoarthritis (OA) of the thumb carpometacarpal (CMC) joint is a common condition that is seen regularly in outpatient occupational therapy and physiotherapy departments.
- Trial name
- NCT00705146
- Testing
- Comfort Cool thumb splint by North Coast Medical, Custom made thermoplastic & neoprene splint
- Where
- 3 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University of British Columbia
Knee Osteoarthritis
Effects of Kinesio-taping in Knee Osteoarthritis Patients.
The main reason to conduct this research is to find the comparison of kinseotaping according to time duration that is 24 hours, 48 hours and 72 hours in knee osteoarthritis patients.
- Trial name
- NCT04585373
- Testing
- kinesio-taping with conventional therapy 24 hours, kinesio-taping with conventional therapy 48 hours, kinesio-taping with conventional therapy 72 hours
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Shoulder Fractures, Shoulder Arthritis Osteoarthritis
Zimmer Biomet Shoulder Arthroplasty PMCF Study
This is a multicenter, prospective, non-controlled post market surveillance study. The objectives of this study are to confirm the safety, performance, and clinical benefits of the Zimmer Biomet Shoulder Arthroplasty systems in…
- Conditions
- Shoulder Fractures, Shoulder Arthritis Osteoarthritis, Shoulder Injury, Shoulder Pain
- Trial name
- NCT06920459
- Testing
- Alliance™ Glenoid
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet
Knee Osteoarthritis
Assessment of Efficacy of a Single Intra-articular Injection of HYALUBRIX 60 in Knee Osteoarthritis
The purpose of this study is to evaluate the effect of one single intra-articular (IA) injection of HYALUBRIX 60® plus physical exercise program (PEP) in terms of pain reduction, compared to PEP alone, in patients with knee…
- Trial name
- NCT06113783
- Testing
- HYALUBRIX 60
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Osteoarthritis Knees Both
Effects of Hip Abductors Strengthening In Knee Osteoarthritis
The aim of my study is to determine the effects of hip abductors strengthening and quadriceps strengthening in comparison with quadriceps strengthening alone in patients with knee osteoarthritis.
- Trial name
- NCT05272124
- Testing
- Hip Abductor Strengthening, Traditional Physical Therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Hip Osteoarthritis, Chronic Pain
Comparative Study Between Steroid Plus Anesthetic Block and CRF in Participants With Hip Osteoarthritis
This will be a prospective, multi-center, double-blinded, randomized study designed to compare the efficacy of Conventional Radiofrequency (CRF) and the anesthetic block of the anterior sensory branches to the hip to control pain…
- Trial name
- NCT04876859
- Testing
- CRF of anterior sensitive branches to the hip, Anesthetic block with steroid injection of anterior sensitive branches to the hip
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Brasilia
Osteoarthritis
Subject Insights to Understand the Hand Osteoarthritis (HOA)
Osteoarthritis (OA) is a degenerative joint disease which causes joints to become painful and stiff. HOA is the second most common form of OA and is characterized by stiffness, joint pain and inflammation and tenderness in the…
- Trial name
- NCT03271203
- Testing
- Michigan Hand Outcomes Questionnaire, Real-time data capture app
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- GlaxoSmithKline
Knee Osteoarthritis, Cartilage Degeneration
Effectiveness of Autologous Adipose-derived Stem Cells in the Treatment of Knee Cartilage Injury
This study was aimed to evaluate the efficacy and safety of Autologous Adipose-derived Mesenchymal Stem Cell Gel combine with High tibial osteotomy therapy in the treatment of cartilage damage in the knee.
- Trial name
- NCT03955497
- Testing
- Autologous Adipose-derived Mesenchymal Stem Cell Gel, Sodium Hyaluronate, Extraction of abdominal fat
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Qilu Hospital of Shandong University
Knee Osteoarthritis
Cartilage Recovery in Adults With Knee Osteorthritis by Mesenchymal Cell Therapy: Randomized Trial of Radiologic and Clinical Outcomes
The treatment of osteoarthritis (OA) of the knee remains still controversial. Despite that fact advanced stages with symptomatic and functional improvement are obtained with total knee replacement, however, there is no treatment…
- Trial name
- INMUNOCEM-OA (NCT05936060)
- Testing
- INMUNOCEM
- Volunteers
- 32 people
- Sponsor
- GUSTAVO SALGUERO
Knee Osteoarthritis
Live and Interactive Fitness Training Program (Vivo Knee OA)
Potential participants will be screened at clinic. Patients who meet eligibility criteria will be considered for study. After written informed consent is obtained, participants will complete baseline testing and participants who…
- Trial name
- LIFT-OA (NCT06462560)
- Testing
- Vivo Online Exercise Program, Medbridge Home program
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- Intermountain Health Care, Inc.
Anterior Knee Pain Syndrome
Does Arthroscopic Patellar Denervation With High Tibial Osteotomy Improve Anterior Knee Pain
Arthroscopy will be done in all cases before osteotomy to assess lat. Comp and grade of patellofemoral O.A Arthroscopic patellar denervation with vaper or diathermy will be done plus open wedge high tibial osteotomy in one group…
- Trial name
- NCT03615976
- Testing
- high tibial osteotomy with or without arthroscopic circumpatellar denervation with or without arthroscopic circumpatellar denervation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Osteoarthritis
Weighted Dangling Exercises vs Vastus Medialis Oblique Muscle Neuromuscular Stimulation for Knee Osteoarthritis
This randomized controlled trial aims to compare the effectiveness Weighted dangling exercises versus vastus medialis oblique muscle neuromuscular electrical stimulation(VMO+NMES) in patients with knee osteoarthritis.
- Trial name
- NCT07701174
- Testing
- Interventional group A, interventional group B
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Lahore
Knee Osteoarthritis
Mulligan and Maitland Techniques in Post PRP Knee Osteoarthritis
Knee osteoarthritis (OA) is a major cause of disability nowadays. Osteoarthritis (OA), also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage.
- Trial name
- NCT06460168
- Testing
- Mulligan(MWM) MobilizationTechnique, Maitland Mobilization technique
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Osteo Arthritis Knee, Knee Arthroplasty
Effects of Motor Imagery Intervention on Functional Recovery Following Total Knee Arthroplasty
The knee osteoarthritis becoming a leading cause of disability among older adults' population. When conventional treatments fail, a total knee arthroplasty (TKA) is suggested.
- Trial name
- KSV2017 (NCT03684148)
- Testing
- Motor imagery practice
- Where
- Slovenia
- Volunteers
- 34 people
- Sponsor
- Science and Research Centre Koper
Osteoarthritis
ActaVisc and ActaVisc Mx Intra-articular Injection for Pain Associated With Osteoarthritis in the Knee
To evaluate the safety and performance of ActaVisc™ intra-articular injection (ActaVisc) and ActaVisc Mx, for management of pain associated with osteoarthritis in the knee in patients who have failed to respond adequately to…
- Trial name
- NCT00665574
- Testing
- ActaVisc and ActaVisc Mx Intra-articular Injection
- Where
- 2 sites in Latvia
- Volunteers
- 23 people
- Sponsor
- Carbylan Therapeutics, Inc.
Osteoarthritis, Knee
Double-Blind, Double Dummy, Randomized Comparison Study to Evaluate the Efficacy and Safety of Valdecoxib 10 mg Once Daily and Naproxen 500 mg Twice Daily in Treating the Signs and Symptoms of Osteoarthritis of the Knee
This study was performed to demonstrate that treatment with valdecoxib 10 mg daily (QD) was at least as effective as with naproxen 500 mg twice daily (BID), a standard non-steroidal anti-inflammatory drug (NSAID), when taken for…
- Trial name
- NCT00652808
- Testing
- valdecoxib, naproxen
- Where
- 8 sites in South Korea
- Volunteers
- 265 people
- Sponsor
- Pfizer
Osteoarthritis, Knee
HTO and Tranexamic Acid Study
The purpose of the study is to assess the effect of Tranexamic acid (TXa), a commonly used medication to prevent bleeding, in reducing blood loss during High Tibial Osteotomy (HTO).
- Trial name
- NCT07825350
- Testing
- Tranexamic Acid, Routine medial opening wedge high tibial osteotomy
- Volunteers
- 200 people
- Sponsor
- Western University, Canada
Thumb Osteoarthritis, Muscle Atrophy or Weakness
Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA
In this study, investigators aimed to investigate the morphometric parameters tenar muscles and joint configuration in patients with trapeziometacarpal osteoarthritis (TMC OA) osteoarthritis stages, thenar muscle parameters…
- Trial name
- NCT04913935
- Testing
- Muscle-Skeleton Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hyaluronic Acid
ArtiAid® Plus for Knee Osteoarthritis: A Post-market Study
The goal of this open-label, post-market clinical follow-up study is to demonstrate the safety and performance of ArtiAid® Plus Intra-articular Injection in patients with knee osteoarthritis(OA).
- Trial name
- NCT05881317
- Testing
- ArtiAid® Plus Intra-articular Injection
- Where
- Taiwan
- Volunteers
- 59 people
- Sponsor
- Maxigen Biotech Inc.
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