Clinical trials: Degenerative Joint Disease
Lumbar Osteoarthritis
Correlation Between the Lower Extremities and Lumbar Degenerative Diseases of the Elderly
The study has before mentioned the concept of "knee - spine syndrome" domestically, on the basement of which, the new study intends to perform another further study on the relationship between lumbar and lower extremity…
- Trial name
- NCT03364790
- Testing
- PLIF, TKA
- Volunteers
- 120 people
- Sponsor
- Peking University People's Hospital
Osteoarthritis, Knee
A Controlled Surveillance of the Osteoarthritic Knee Microenvironment With Regenexx® SD Treatment
The primary objective of this study is to determine the levels of proteins and/or cellular components of the synovial fluid that are indicative of microenvironment phenotypes of the osteoarthritic knee compared to unilateral…
- Trial name
- NCT02370823
- Testing
- Regenexx SD
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Regenexx, LLC
Osteoarthritis, Knee
Proximal Tibial Open Wedge Osteotomy. A Clinical Prospective, Randomized RSA-trial.
In the treatment of osteoarthritis of the medial compartment of the knee, Open wedge high tibial osteotomy is a good choice of treatment for the young and active patient.
- Trial name
- NCT00319280
- Testing
- bonesubstitution (Calcibon, Iliac Crest Bonegraft, control)
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Knee Osteoarthritis
Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis
This is a single-center, prospective, randomized, single-blind, comparator therapy, parallel group study for symptomatic patients diagnosed with knee osteoarthritis.
- Trial name
- NCT03491761
- Testing
- PRP Treatment, HA Treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Endeavor Health
Knee Osteoarthritis, Hip Osteoarthritis
The STavanger osteoARThritis Study
The START study will implement osteoarthritis (OA) treatment recommendations to increase the use of recommended treatment modalities and reduce non-desired events (e.g.
- Trial name
- START (NCT02876120)
- Testing
- Implementation
- Volunteers
- 330 people
- Sponsor
- Diakonhjemmet Hospital
OA Knee, OA Knee Pain
Comparison of Medial Knee Pain Between Patients With and Without Preoperative Tibia Vara Underging Mobile-bearing Unicompartmental Knee Arthroplasty
to compared VAS for medial knee pain between oa knee with or without tibia vara following mobile bearing UKA
- Conditions
- OA Knee, OA Knee Pain, Osteoarthritis
- Trial name
- bow leg (NCT07720024)
- Testing
- mobile bearing UKA
- Where
- Thailand
- Volunteers
- 150 people
- Sponsor
- Thammasat University
Knee Osteoarthritis
Evaluating the Efficacy and Safety of Intra-articular Injection of HS-20116 in Patients With Knee Osteoarthritis
The purpose of this trial is to evaluate the efficacy and safety of HS-20116 for intra-articular use in patients with symptomatic knee osteoarthritis.
- Trial name
- NCT07047196
- Testing
- HS-20116, Medical Chitosan (for intra-articular injection)
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Knee Arthritis, Osteoarthritis
Eccentric vs Low-Load Blood Flow Restriction Training in Knee Osteoarthritis in Knee Osteoarthritis
The aim of this randomized controlled trial is to find the effects of eccentric and low-load blood flow restriction training on neuromuscular adaptations, muscle strength, functional performance, and disability in patients with…
- Trial name
- the (NCT07733518)
- Testing
- Eccentric Gastrocnemius Strengthening Exercises, Low-Load Blood Flow Restriction Training
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Hip Osteoarthritis
Effects of Chiropractic Care in Patients With Hip Osteoarthritis
The purpose of the study is to explore the short term effects of chiropractic care on pain and function in patients with hip osteoarthritis.
- Trial name
- NCT01025661
- Testing
- Chiropractic care
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Scandinavian College of Chiropractic
Osteoarthritis of Hip
Management of Postoperative Pain After Total Hip Arthroplasty
Orthopedic surgery is reportedly among the most painful surgical procedures. Surgical damage following major orthopedic surgery often involves a large, deep incision with considerable tissue dissection and muscle, bone, and…
- Trial name
- NCT01040273
- Testing
- Bupivacaine
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Arthrosis, Osteoarthrosis
HUD: PIP Joint Implant
This surgery involves the use of a finger joint replacement device for treatment of patients with certain kinds of arthritis (osteo - arthritis or post traumatic arthritis) and who expect to place their hands in heavy loading…
- Trial name
- NCT02434913
- Testing
- SR PIP Implant System
- Sponsor
- The Hawkins Foundation
Osteoarthritis
Progressive Exercise After Total Knee Arthroplasty (TKA)
Total knee arthroplasty (TKA) is performed more than 7.000 times a year in Finland most often for osteoarthritis (OA). While pain is predictably reduced, function does not typically ever reach that of age-matched, uninjured…
- Trial name
- NCT00605124
- Testing
- Knee muscle exercises
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Jyväskylä Central Hospital
Knee Osteoarthritis
Effect of Retro Walking Versus Isometric Multi-angular Exercises on Pain and Functional Performance in Knee Osteoarthritis in Geriatric Population
Osteoarthritis is a leading musculoskeletal cause of disability in elderly persons all over the world and a major cause of physical limitations and reduced quality of life (1).
- Trial name
- NCT06274346
- Testing
- Multiangular Isometric exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology
Osteoarthritis, Knee, Osteo Arthritis Knee
Study to Evaluate Resiniferatoxin in Patients With Knee Osteoarthritis Whose Total Knee Replacement Surgery is Delayed
Efficacy and safety study of resiniferatoxin versus placebo to manage pain in patients with knee osteoarthritis whose TKR surgery is delayed
- Conditions
- Osteoarthritis, Knee, Osteo Arthritis Knee, Knee Pain Chronic
- Trial name
- NCT04386980
- Testing
- Resiniferatoxin
- Sponsor
- Sorrento Therapeutics, Inc.
Osteoarthritis
The Use of Compression Bandages in Total Knee Replacement Surgery
The use of compression bandages in elective orthopaedic knee surgery is well regarded, however, there is a lack of robust, well-designed evidence to support this.
- Trial name
- NCT02253680
- Testing
- Actico, short-stretch, inelastic dressing
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Northumbria Healthcare NHS Foundation Trust
Osteo Arthritis of the Knee
A Study to Evaluate Efficacy and Safety of a Single Intra-Articular Injection of HL-01 in the Treatment of Pain in Symptomatic Knee Osteoarthritis
The goal of this clinical trial is to test HL-01 in patients with knee osteoarthritis pain. The main question[s] it aims to answer are: Measure the change in average daily knee pain intensity scores from baseline to the end of…
- Trial name
- NCT07819461
- Testing
- Sodium hyaluronate solution - 3.36%, Sterile buffered solution
- Volunteers
- 704 people
- Sponsor
- IBSA Institut Biochimique SA
Erosive Osteoarthritis, Psoriatic Arthritis
microRNA in Erosive Hand Osteoarthritis and Psoriatic Arthritis
Erosive osteoarthritis of the hand (EHOA) is a rare subset of HOA that affects mainly postmenopausal middle-aged women, featured by prominent signs of inflammation, severe progression, and typical radiographic changes of the…
- Trial name
- NCT05683769
- Testing
- miRNA
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Siena
Pain
Study to Evaluate the Efficacy and Safety of OraVescent Fentanyl Citrate Treatment for the Management of Breakthrough Pain in Opioid-Tolerant Patients With Noncancer-Related Chronic Pain
The purpose of the study is to evaluate the efficacy and safety of OraVescent fentanyl treatment compared to placebo treatment monthly over a 12-week treatment period in alleviating breakthrough pain (BTP) in opioid-tolerant…
- Trial name
- NCT00343733
- Testing
- OraVescent Fentanyl
- Where
- 21 sites in United States
- Volunteers
- 120 people
- Sponsor
- Cephalon
Knee Osteoarthritis
The Knee Usual Care Evaluation Study
The purpose of this prospective data collection is to track patients who are treated at HSS who are confirmed with knee osteoarthritis.
- Trial name
- KUCE (NCT01905358)
- Where
- United States
- Volunteers
- 906 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Osteoarthritis
Effectiveness of Knee Sync Partner and Strengthening Exercises Versus Strengthening Exercises in Knee Osteoarthritis.RCT
This study explores the effectiveness of a novel treatment approach for knee osteoarthritis (OA) by comparing the combined use of a new device, "Knee Sync Partner," which provides electrical knee traction with stimulation and…
- Trial name
- NCT06664632
- Testing
- Exp, control
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Superior University
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