Clinical trials: Degenerative Meniscal Tears
Meniscal Degeneration, Osteoarthritis, Knee
Comparing Different Types of Physical Therapy for Treating People With a Meniscal Tear and Osteoarthritis
Knee osteoarthritis is a disabling problem affecting over 15 million adults in the United States. Many people who have knee arthritis also experience painful meniscal tears.
- Trial name
- TeMPO (NCT03059004)
- Testing
- TeMPO Home Exercise Program, Motivational SMS Messages, In-Clinic Topical Therapy
- Where
- 4 sites in United States
- Volunteers
- 879 people
- Sponsor
- Brigham and Women's Hospital
Anterior Cruciate Ligament Injuries, Meniscus Tear
Magic Angle Direction Imaging (MADI) ACL Study
This study will be conducted to see if a new Magnetic Resonance Imaging (MRI) scanner could give additional information or help view the body in a different way.
- Trial name
- MADI (NCT07366619)
- Testing
- Magnetic Resonance Imaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Meniscus Tear, Knee Injuries
Investigation of the Effectiveness of Neuromuscular Exercise Program Accompanied With Degenerative Meniscal Tear
The aim of the study was to investigate the effect of exercise program added to the treatment on physical function, postural balance, muscle strength, pain and gait in individuals with meniscal damage.
- Trial name
- NCT06657586
- Testing
- neuromuscular exercises, conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medipol University Hospital
Knee Pain Chronic
Arthroscopic Versus Conservative Treatment of Degenerative Meniscal Tear in Middle Aged Patients in Regard to Pain & Knee Function
The study is prospective comparative study, conducted in Erbil teaching hospital on 60 patients, their age ranging between 40 and 60 years.
- Trial name
- NCT04313569
- Testing
- Arthroscopic menisctomy
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- Hawler Medical University
Osteoarthritis, Knee, Meniscus; Degeneration
Knowledge Translation and Exercise for Degenerative Meniscal Tears and Early Osteoarthritis: KNEE-DEeP Study
Knee pain due to a degenerative meniscal tear (DMT) or early osteoarthritis (OA) is a frequent presentation in middle-aged and older adults.
- Trial name
- KNEE-DEeP (NCT06576557)
- Testing
- KNEE-DEeP intervention- Knowledge translation and exercise for early degenerative knee pain
- Where
- Ireland
- Volunteers
- 36 people
- Sponsor
- University of Limerick
Degenerative Meniscal Tear
Surgical or Exercise Therapy on Patients With Degenerative Meniscus Tears
This study is conducted as a collaboration between NAR, Orthopedic Department, Oslo University Hospital,Ullevaal, Hjelp24Nimi Oslo, Martina Hansens Hospital Norway, and University of Southern Denmark, Odense, Denmark.
- Trial name
- OMEX (NCT01002794)
- Testing
- Arthroscopic partial menisectomy, Supervised neuromuscular and strength training
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Degenerative Meniscus Tear
The Benefit of Arthroscopic Partial Meniscectomy in Middle-Aged Patients
BACKGROUND Osteoarthritis (OA) is the most common form of arthritis and the knee is one of the most affected joints. The meniscus plays an important role in the development of knee OA.
- Trial name
- SLAMSHAM (NCT01264991)
- Testing
- Arthroscopic partial meniscectomy
- Where
- 2 sites in Denmark
- Volunteers
- 41 people
- Sponsor
- Slagelse Hospital
Degenerative Disease, Meniscus Tear
The Video-Based Exercise Programs in Degenerative Meniscus Tears
This randomized controlled trial aims to investigate the efficacy of the video-based exercise programs in patients with degenerative meniscus tears.
- Conditions
- Degenerative Disease, Meniscus Tear, Knee Pain Swelling
- Trial name
- NCT05266365
- Testing
- The video-based exercise (VBE), The standard exercise (SE), The hybrid exercise (HE)
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Istanbul University - Cerrahpasa
Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear
Clinical Efficacy of Exosome in Degenerative Meniscal Injury
Comparison of intra-articular administration of synovial fluid-derived mesenchymal stem cells-derived exosomes with synovial fluid-derived mesenchymal stem cells on the same patient.
- Conditions
- Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear, Meniscus Lesion, Meniscus; Degeneration
- Trial name
- KNEEXO (NCT05261360)
- Testing
- SF-MSC-EX, SF-MSC
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
Knee Osteoarthritis, Meniscus Tear
Effects of Kinesiotaping and Physiotherapy in Grade 2 Osteoarthritis Following Degenerative Meniscal Tears
Degenerative meniscal tears are a common cause of osteoarthritis commonly diagnosed in football players and are considered a major risk factor for the development of knee osteoarthritis.
- Trial name
- NCT06227078
- Testing
- Kinesiotaping
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- Gopal Nambi
Osteoarthritis
Meniscal Tear and Osteoarthritis Risk (MenTOR)
Adults with degenerative meniscal tear receiving arthroscopic surgical management or knee drainage (arthrocentesis) +/- intra-articular steroid injection will be recruited to this non-interventional cohort study.
- Trial name
- MenTOR (NCT02684864)
- Testing
- Non-interventional
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Oxford
Knee Osteoarthritis, Cartilage Damage
Clinical Study of Pain Reduction by Peri-arthroscopic PRP Application in Knee Degeneration
The purpose of this study is to investigate reduction of pain, gain of function and improvement of life quality by intraoperative applied platelet- rich- plasma ( PRP ) during knee arthroscopy for degeneration and osteoarthritis…
- Conditions
- Knee Osteoarthritis, Cartilage Damage, Meniscal Tear
- Trial name
- PRP-Bochum (NCT02189408)
- Testing
- Platelet rich plasma
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- Ruhr University of Bochum
Degenerative Meniscal Tears, Knee Osteoarthritis
DEMAND - DEgenerative Meniscal Tears - Arthroscopy vs. Dedicated Exercise
Patients with wear and tear in their knees (osteoarthritis) are often referred to orthopaedic surgeons following a sudden worsening of pain and mechanical symptoms (grinding, locking, giving way) in their knee due to tears of…
- Trial name
- DEMAND (NCT02113280)
- Testing
- Arthroscopy, Physiotherapy
- Where
- United Kingdom
- Sponsor
- Northumbria Healthcare NHS Foundation Trust
Osteoarthritis of the Knee, Arthroscopy
Development of Knee Osteoarthritis After Arthroscopic Partial Resection of Degenerative Meniscus Tear
It has been previously demonstrated that the risk for the development of knee osteoarthritis is increased after both meniscus tear and meniscectomy.
- Conditions
- Osteoarthritis of the Knee, Arthroscopy, Meniscal Tear
- Trial name
- NCT01052233
- Testing
- Arthroscopic partial meniscectomy, Arthroscopy (diagnostic)
- Where
- 5 sites in Finland
- Volunteers
- 160 people
- Sponsor
- Tampere University
Meniscus Tear, Meniscus Lesion
Study of Clinical Performance and Safety of Treatments in Degenerative Meniscopathy With Injection of Polynucleotides
This is a non-randomized multicentre study for the evaluation of the clinical performance and safaty of the augmentation-to-surgery and conservative treatments for the degenerative meniscopathies, with injection of polynucleotide…
- Trial name
- NCT05322005
- Testing
- partial meniscectomy, Condrotide® (polynucleotides gel: class III medical device)
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 60 people
- Sponsor
- Mastelli S.r.l
Meniscus Tear
Prospective Trial of Arthroscopic Meniscectomy for Degenerative Meniscus Tears
Arthroscopic meniscectomy is among the most commonly performed orthopedic surgical procedures in the VA system. There remains substantial uncertainty, however, regarding the short term benefits and the long term consequences of…
- Trial name
- NCT01931735
- Testing
- Randomized Meniscectomy, Randomized Lavage, Standard of Care Meniscectomy Pre-Amend
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- VA Office of Research and Development
Meniscus Disorder, Meniscus; Degeneration
Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment
The aim of this study is to assess outcomes of Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment
- Conditions
- Meniscus Disorder, Meniscus; Degeneration, Meniscus Tear, Meniscus Lesion
- Trial name
- NCT05882591
- Testing
- Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment by the means of published technique (reference nr 1).
- Where
- Poland
- Volunteers
- 10 people
- Sponsor
- Artromedical Konrad Malinowski Clinic
Meniscus Tear
The Effect of Therapeutic Exercise on Cartilage Morphology and Physical Function for Individuals at High Risk of Knee Osteoarthritis
This randomized controlled trial aims to evaluate the efficacy of progressive resistance exercises (PRE) versus aerobic exercises on cartilage morphology and physical function in patients with degenerative meniscus tears.
- Trial name
- NCT06532851
- Testing
- Progressive Resistance Exercise (PRE), Aerobic Exercise, Control
- Where
- 2 sites in Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Meniscus Tear, Chondropathy/Degenerative Joint Disease (DJD)
Post-op Treatment With Hyaluronic Acid Injections
This study will look at patients with post-operative treatment of a meniscal tear or degenerative joint disease (degenerative arthritis).
- Trial name
- NCT01256788
- Testing
- Euflexxa, Saline
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- The Hawkins Foundation
Osteoarthritis, Knee, Meniscus Tear
Corticosteroid Meniscectomy Randomized Trial
Synovitis has an important role in the symptoms and progression of Osteoarthritis (OA). Inflamed synovium has been associated with both increased symptoms and increased progression in OA patients.
- Conditions
- Osteoarthritis, Knee, Meniscus Tear, Meniscus; Degeneration, Synovitis
- Trial name
- CoMeT (NCT04641351)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic