Clinical trials: Degenerative Osteoarthritis
Osteoarthritis of the CMC-1 Joint
TRACE - Thumb Base Replacement Arthroplasty for Osteoarthritis.
Osteoarthritis in the base of the thumb is one of the most common forms of hand arthritis. It usually appears in middle age, particularly in women, and can cause significant pain and loss of function.
- Trial name
- TRACE (NCT07178223)
- Testing
- Arthroplasty CMC-1
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis
Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials
This study is the clinical validation component of a broader research program developing a randomized controlled trial (RCT) comparing sensitization acupuncture (an individualized technique in which treatment points are selected…
- Trial name
- NCT07868224
- Testing
- Sensitization Acupuncture, Traditional Acupuncture
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Hand Osteoarthritis
Effect of the Interleukin-6 Receptor Antagonist Tocilizumab in Patients With Hand Osteoarthritis
Hand osteoarthritis (HOA) which affects the interphalangeal joints and the metacarpophalangeal of the thumb is a common disease, the prevalence of which being about 30 % of the population over than 70.
- Trial name
- TIDOA (NCT02477059)
- Testing
- tocilizumab, saline solution
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Osteoarthritis (Knee OA)
Evaluation of a Preoperative Education in Total Knee Arthroplasty
The benefit of preoperative rehabilitation treatment combining physiotherapy and targeted education for patient undergoing Total Knee replacement (TKR) is now well known.
- Trial name
- EPOP (NCT01747759)
- Testing
- Kruskal-Wallis and qualitative parameters
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Clermont-Ferrand
Shoulder Osteoarthritis, Arthropathy Shoulder
Scapular Positioning in Standing Position Using Sonography
The objective of this study is to analyse the positioning of the scapula in standing position and compared to the supine position (CT scan) in 3 dimensions (3 rotations of the scapula) using a non-radiant, portable system…
- Trial name
- 3S (NCT04449146)
- Testing
- Scapular positioning in Standing position using Sonography
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Necrosis of Femoral Head, Knee Osteoarthritis
CSF Cholinergic Biomarkers and Postoperative Cognitive Change
Previous study demonstrated that the condition of central cholinergic nerve is important for the postoperative cognitive dysfunction.
- Conditions
- Necrosis of Femoral Head, Knee Osteoarthritis, Fracture of Lower Limb
- Trial name
- NCT02063542
- Where
- China
- Volunteers
- 102 people
- Sponsor
- RenJi Hospital
Osteoarthritis (OA) of the Knee, Fear of Needles
Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?
This study aims to investigate factors that affect the subjective experience of pain during and after intra-articular knee joint injection of steroids by comparing needle gauge size (22 G vs 25 G needles), as well as the presence…
- Trial name
- NCT06865170
- Testing
- 25 gauge needle, 22 gauge needle, +/- Ethyl Chloride Topical Aerosol Anesthetic
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Osteoarthritis, Knee
Use of Fresh Platelet Rich Plasma With Concentrated Leukocytes or Fresh Platelet Rich Plasma Without Concentrated Leukocytes in the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial
The aim of the study is to compare the triple infiltration of Fresh Platelet Rich Plasma with concentrated Leukocytes against triple infiltration of Fresh Platelet Rich Plasma Without Concentrated Leukocytes in the treatment of…
- Trial name
- PRP019 (NCT04187183)
- Testing
- Fresh Platelet Rich Plasma with leukocyte, Fresh Platelet Rich Plasma without leukocyte
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Istituto Ortopedico Rizzoli
Total Knee Replacement
Effects of OEP on Rehabilitation Outcomes on TKR Patients
The aim of this research is to assess the effects of the Otago Exercise Program on Rehabilitation outcomes of balance strength and functional outcomes of post Total Knee Replacement patients.
- Trial name
- NCT06190977
- Testing
- Otago Exercise Program, General TKR pprotocol
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Osteoarthritis, Hip, Osteoarthritis, Knee
Tai Chi or Hydrotherapy for People With Osteoarthritis of the Hip(s) or Knee(s)
The aim of this study is to determine, in the framework of a randomized controlled clinical trial, whether Tai Chi can affect measurable improvements in self-reported outcomes such as pain, physical function and psychological…
- Trial name
- NCT00123994
- Testing
- Tai Chi classes, Hydrotherapy classes
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- St George Hospital, Australia
Subscapularis Peel, Morselized Osteotomy
Comparing Two Surgical Methods of Fixation of Subscapularis During Shoulder Arthroplasty
This pilot study is being conducted to compare 2 methods of access to the shoulder for arthroplasty in patients with Osteoarthritis as we do not know has a better outcome.
- Trial name
- NCT00508105
- Testing
- subscapularis peel, osteotomy
- Where
- Canada
- Volunteers
- 87 people
- Sponsor
- Ottawa Hospital Research Institute
Knee Osteoarthritis, Knee Osteoarthritis (OA)
Knee Osteoarthritis and Spa Therapy
The aim of this clinical trial is to assess the efficacy of the 18-day balneotherapy program (therapeutic indication: Rheumatology) in terms of functional incapacity and the disorders (pain, joint stiffness) induced by…
- Trial name
- SANTIAGO (NCT06617975)
- Testing
- Balneotherapy program in rheumatology indication
- Where
- France
- Volunteers
- 80 people
- Sponsor
- CEN Biotech
Osteoarthritis
Transcatheter Arterial Micro-Embolization (TAME) Using Nexsphere-F in Patients With Knee Degenerative Osteoarthritis
Among knee degenerative osteoarthritis patients aged 50 or older, it will prove the therapeutic effect and safety of Nexsphere-F embolization for patients who need additional treatment because pain is not controlled even if…
- Trial name
- NCT05917028
- Testing
- Transcatheter Arterial Micro-Embolization
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Next Biomedical Co., Ltd.
Osteoarthritis, Total Knee Arthroplasty
Antero-Posterior Knee Stability
A retrospective one-time evaluation of total knee patients one year or more postoperative, to compare antero-posterior (AP) stability with the TELOS Stress device/stress x-rays and clinical outcomes.
- Conditions
- Osteoarthritis, Total Knee Arthroplasty, Stability, Knee Osteoarthritis
- Trial name
- NCT03387839
- Testing
- Stress X-Ray
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- David F. Scott, MD
Osteoarthritis, Knee
Knee Osteoarthritis Disabling Pain Program for the Brazilian Unified Health System
This is a Randomized Clinical Trial to compare two interventions for reducing knee pain and improving knee function of patients with knee osteoarthritis.
- Trial name
- NCT05286775
- Testing
- Clinical treatment and Knee educational program, Knee educational program
- Where
- Brazil
- Volunteers
- 71 people
- Sponsor
- Marta Imamura
Knee Pain Chronic, Knee Osteoarthritis
Prevention, Management and Rehabilitation of Knee Osteoarthritis at the Workplace
The goal of this intervention study is to assess the effect of blood flow restricted (BFR) exercise integrated into the daily work tasks among hospital workers with or at increased risk of chronic knee pain.
- Conditions
- Knee Pain Chronic, Knee Osteoarthritis, Knee Discomfort
- Trial name
- NCT05822401
- Testing
- Blood flow restriction (BFR), Usual care (control)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Research Centre for the Working Environment, Denmark
Osteoarthritis, Hip, Inflammation
Correlation of the Inflammatory Parameters With Pain and Radiological Findings in Coxarthrosis
Osteoarthritis (OA) is a functional disease with joint degeneration with subchondral and periosteal lesions. Coxarthrosis (or hip osteoarthritis) is an important cause of disability, especially in the advanced age group.Although…
- Conditions
- Osteoarthritis, Hip, Inflammation, Pain
- Trial name
- NCT04796129
- Testing
- the patients with hip osteoarthritis and their inflammatory status
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Osteoarthritis
Osteoarthritis, Balance, and Fear of Falling
Osteoarthritis (OA) is a progressive and irreversible degenerative joint disease characterized by marginal bone hypertrophy, erosion, and subchondral sclerosis in the articular cartilage.It has been determined that being of…
- Trial name
- OA (NCT04660357)
- Testing
- survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
Knee Osteoarthritis
Evaluation of Safety and Efficacy of ReHub in Patients Who Underwent Primary Total Knee Arthroplasty
This is a randomized, non-blinded, parallel assignment, clinical trial for the evaluation of safety and efficacy of ReHub, a telerehabilitation system made up of a cloud platform and an exercise kit with smart sensors, for…
- Trial name
- REHAPT (NCT04155957)
- Testing
- Rapid Recovery Rehabilitation Programme, ReHub
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Bio-Sensing Solutions S.L. (DyCare)
Osteoarthritis, Knee
A Single Intra-articular Injection of aMAT vs PRP in Patients With OA of the Knee
The study proposes to compare performances and safety of intra-articular injections of aMAT with those of a control group (PRP injections) for the treatment of symptomatic OA of the knee.
- Trial name
- LIPOJOINT (NCT03117608)
- Testing
- injection of autologous micro-fragmented adipose tissue (aMAT), injection of Platelet-rich Plasma (PRP)
- Where
- Italy
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Lipogems International spa
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