Clinical trials: Degenerative Osteoarthritis
Knee Osteoarthritis
Effects of Kinesio-taping in Knee Osteoarthritis Patients.
The main reason to conduct this research is to find the comparison of kinseotaping according to time duration that is 24 hours, 48 hours and 72 hours in knee osteoarthritis patients.
- Trial name
- NCT04585373
- Testing
- kinesio-taping with conventional therapy 24 hours, kinesio-taping with conventional therapy 48 hours, kinesio-taping with conventional therapy 72 hours
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Osteoarthritis
Safety, Tolerability, Pharmacokinetics and -Dynamics of Multiple Rising Oral Doses of BI 113823 in Patients Patients With Osteoarthritis of the Knee
The objective of the study is to investigate the safety and tolerability of BI 113823 in male and female patients with osteoarthritis, following oral administration of BI 113823 with repeated rising doses.
- Trial name
- NCT01207973
- Testing
- BI 113823
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Boehringer Ingelheim
Knee Osteoarthritis
Cost Effectiveness of Prolotherapy Injections Prior to Total Knee Arthroplasty
This study compared the cost effectiveness of two-stage algorithm (prolotherapy injections (PrT) combined with rehabilitation protocol (RP) prior to total knee arthroplasty (TKA)) and one-stage algorithm (TKA) in the management…
- Trial name
- NCT03758183
- Testing
- total knee arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 197 people
- Sponsor
- Tokat State Hospital
Osteoarthritis, Hip Arthropathy
Topical Tranexamic Acid (TXA) in Joint Arthroplasty
The objective of this study is to evaluate the efficacy of topical tranexamic acid (TXA) in decreasing blood loss following both shoulder arthroplasty and primary total hip arthroplasty.
- Conditions
- Osteoarthritis, Hip Arthropathy, Shoulder Arthropathy
- Trial name
- NCT01937559
- Testing
- Tranexamic acid (TXA), Normal saline
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- The Hawkins Foundation
Osteoarthritis
Effectiveness of Manual Therapy and Exercise in Shoulder OA
Approximately 60 subjects from a sample of convenience diagnosed with shoulder arthritis will be randomized into a two groups. The control group will receive usual medical advice and the experimental group will be referred to…
- Trial name
- NCT02587559
- Testing
- physical therapy
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Osteoarthritis, Blood Loss, Surgical
Non-inferiority Trial of Oral Tranexamic Acid vs. Intravenous Tranexamic Acid in Joint Replacement Surgery
The purpose of this research is to determine if the oral form of a medication (tranexamic acid) to reduce bleeding can be used in place of an intravenous (IV) form, to learn the best way to give tranexamic acid: either a pill by…
- Conditions
- Osteoarthritis, Blood Loss, Surgical, Blood Loss, Postoperative
- Trial name
- NCT02438566
- Testing
- Tranexamic Acid (Oral), Tranexamic Acid (Intravenous)
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- The New England Baptist Hospital
Osteoarthritis of Multiple Joints
Probiotic for Pain Osteoarthritis
Many people with symptomatic Osteoarthritis (OA) report chronic joint pain, especially if those patients are older than 50 years.
- Trial name
- NCT03968770
- Testing
- Experimental group, Control group, Usual medical care
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Osteoarthritis
Transcatheter Arterial Micro-Embolization (TAME) Using Nexsphere-F in Patients With Chronic Pain in Elbow or Wrist
In patients with chronic elbow or wrist pain, the pain is controlled by conventional conservative therapy The pain reduction effect of Nexsphere-F embolization in patients who need additional treatment It is intended to…
- Trial name
- NCT06207851
- Testing
- Transcatheter Arterial Micro-Embolization
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Next Biomedical Co., Ltd.
Hip Osteoarthritis, Knee Osteoarthritis
Pilot RCT Comparing Effectiveness of Two Decision Aids for Hip and Knee Osteoarthritis
This pilot RCT study is to examine the comparative effectiveness of two decision aids for hip and knee osteoarthritis.
- Trial name
- NCT02625402
- Testing
- Brief interactive decision aid, Long video decision aid
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Massachusetts General Hospital
Osteoarthritis, Knee
Comparative Efficacy and Tolerability of No7 in Osteoarthritis of the Knee
This study evaluates the effect of dietary supplement Solgar No7 in 76 adult Osteoarthritis of the Knee Patients, while the other half will receive placebo.
- Trial name
- NCT03442153
- Testing
- Solgar No7 Complex
- Volunteers
- 76 people
- Sponsor
- Ambrosia - SupHerb Ltd.
Knee Osteoarthritis
ACB With S-ESPB Versus ACB With iPACK for Knee Arthroplasty
This study will compare two regional anesthesia strategies for pain management after total knee arthroplasty in adults. Both strategies use an adductor canal block (ACB) to provide analgesia while preserving quadriceps muscle…
- Trial name
- NCT07288970
- Testing
- Adductor Canal Block, Sacral Erector Spinae Plane Block, iPACK Block
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Medical Sciences
Knee Osteoarthritis
Homologus PRP in the Infiltrative Treatment of Knee Osteoarthritis in Young Athletic Patients
The study consists of 3 phases (enrollment, infiltrative procedure, and controls): Identification by specialized orthopedic medical staff belonging to the SC Orthopedic and Trauma Clinic II of the Rizzoli Orthopedic Institute of…
- Trial name
- NCT06483269
- Testing
- PRP infiltration
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Knee Osteoarthritis, Biofiller PRP
Evaluation of the Effect of Biofiller PRP Application on Knee Osteoarthritis
The aim of this study is to evaluate the effects of biofiller PRP on function, pain level, and femoral cartilage thickness in knee osteoarthritis: a randomized clinical study
- Conditions
- Knee Osteoarthritis, Biofiller PRP, Femoral Cartilage Thickness
- Trial name
- NCT06946056
- Testing
- Biofiller platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Knee Osteoarthritis
Physica CR and Physica PS Clinical Trial
Type \& Design: Post-market, international, multicentre Prospective, parallel groups, open-label, baseline controlled Objectives: 1.
- Trial name
- NCT02766231
- Testing
- Physica CR, Physica PS
- Where
- 4 sites in Belgium, Italy and 1 more
- Volunteers
- 157 people
- Sponsor
- Limacorporate S.p.a
Rehabilitation, Excercise
The ACT-ON: A Geriatric 5-Ms-Guided Physical Therapy Intervention for Knee Osteo-Arthritis in Older Adults.
The study is a Random control trail study conducted at King Khalid University Hospital in Riyadh, Saudi Arabia, focusing on Application of 5 framework in rehabilitation program of knee arthritis.
- Conditions
- Rehabilitation, Excercise, Geriatric, Physical Therapy
- Trial name
- 5Ms/PT/KOA/OA (NCT07640529)
- Testing
- Geriatric 5Ms framework, Exercises PT
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Saud University
DVT, Osteoarthritis
Does Thinning the Blood During Surgery Prevent Blood Clots Following Total Knee Replacement Surgery
The goal of this study is to prevent blood clots from forming during surgery and a few days after total knee replacement surgery.
- Trial name
- NCT00253851
- Testing
- unfractionated heparin
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis
Lesser Tuberosity Osteotomy for Subscapularis Repair
The primary objective of this study is to assess the clinical effectiveness of two different techniques used for subscapularis tendon repair during total shoulder replacement.
- Trial name
- NCT02762903
- Testing
- TSA with tenotomy technique, TSA with lesser tuberosity osteotomy technique, Shoulder prosthesis
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Knee Osteoarthritis
Comparing Effect of Autologous Platelet-Rich Plasma Versus Hyaluronic Acid Treatment on Knee Osteoarthritis
To compare the efficacy and structural change of intraarticular single platelet-rich plasma(PRP) versus novel crosslinked Hyaluronic Acid(HA)(HyajointPlus) for the treatment of early stage knee osteoarthritis(OA).
- Trial name
- NCT04972383
- Testing
- Platelet Rich Plasma, Hyaluronic Acid
- Where
- Taiwan
- Volunteers
- 116 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Osteoarthritis
Effects of ASC Secretome on Human Osteochondral Explants
Since the need of finding effective disease-modifying anti-osteoarthritis (OA) treatments is still unmet, with this study the investigators aim to gather further evidences of the therapeutic potential of Mesenchymal Stem/stromal…
- Trial name
- ASC-OA (NCT04223622)
- Testing
- ASC secretome
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Knee Osteoarthritis
Evaluation of the Effect of the "CR500 SINGLE-DOSE GEL" Medical Device in Patients With Knee Osteoarthritis (KOA)
Single arm clinical investigation, post-market confirmatory interventional to assess performance, safety and tolerability of "CR500 SINGLE-DOSE GEL" medical device in patients with knee osteoarthritis (KOA).
- Trial name
- NCT05661162
- Testing
- CR 500™ SINGLE-DOSE GEL
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Contrad Swiss SA
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