Clinical trials: Deglutition Disorder
Dysphagia Following Cerebrovascular Accident
Effect of Home Based Swallowing Exercise in Stroke Patients With Dysphagia
Dysphagia is a common problem in post-stroke patients and greatly impaired quality of life. Among them, the strength of tongue and lip muscles played a key role in the oral phase of swallowing and many stroke survivors suffered…
- Trial name
- NCT05758350
- Testing
- home based IOPI swallow training
- Volunteers
- 100 people
- Sponsor
- Taichung Veterans General Hospital
Gastro Esophageal Reflux
Gastroesophageal Reflux Disease in the Dutch Population
Rationale: Screening for esophageal adenocarcinoma (EAC) precursors and treating them may help to decrease mortality of this malignancy.
- Trial name
- REFLUX (NCT05689918)
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 4,719 people
- Sponsor
- Radboud University Medical Center
Barrett's Esophagus
Prospective Study to Compare the Efficacy of E.G.Scan to Detect Barrett's Esophagus Compared With Standard Endoscopy
The purpose of this study was to evaluate whether a disposable nasal endoscope called "E.G. Scan II" will visualize the esophagus as well as the standard test, sedated endoscopy.
- Trial name
- NCT02066233
- Testing
- EG Scan II (transnasal endoscopy), Standard Endoscopy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Herpes Esophagitis, Vocal Fold Palsy
Unusual Clinical Findings of Herpes Esophagitis
Herpes esophagitis presents a clinical diagnostic challenge. The investigators report the first case of herpes esophagitis presenting as vocal fold palsy in an immunocompetent host.
- Trial name
- NCT01501526
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Gastro-esophageal Reflux Disease With Ulceration.
Relationship of Obesity With GERD Among Nigerians
Obesity is a strong risk factor for GERD. This study assessed the role of obesity among patients having erosive GERD and controls.
- Trial name
- NCT02888808
- Testing
- Gastroscopy
- Volunteers
- 160 people
- Sponsor
- Obafemi Awolowo University Teaching Hospital
GERD, Reflux
Role of ARMA in Selective Subset of Refractory GERD Patients.
To study the role of a novel endoscopic treatment technique (ARMA) in GERD patients who doesn't respond to PPI therapy (Proton Pump Inhibitor).
- Conditions
- GERD, Reflux, Reflux Esophagitis
- Trial name
- NCT05899491
- Testing
- ARMA, UGI Endoscopy
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Dysphagia
The Effect of Swallowing Training for Elderly People in the Community
The goal of this clinical trial is to explore the impact of systematic simple swallowing training on swallowing function and quality of life in community-dwelling elderly individuals (≥60 year old) with swallowing disorders.
- Trial name
- ST (NCT06201091)
- Testing
- Systematic simple swallowing training
- Where
- China
- Sponsor
- Zeng Changhao
Quality of Life (QOL), Tracheostomy
Feeding Difficulties and Quality of Life in Children With Tracheal Cannula
The over all goal of this observational study is to study if there is an association between the presence of feeding difficulties and self-assessed quality of life in children with tracheal cannula.
- Conditions
- Quality of Life (QOL), Tracheostomy, Children in the Pediatric Intensive Care Unit or General Pediatric Care Unit Requiring a Central Venous Catheter, Feeding Difficulties
- Trial name
- NCT06893458
- Where
- 2 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Sleep Apnea, Obstructive, Healthy
Swallowing in OSA & CPAP Intolerance
This study has two parts: an observational part and an interventional part. The goal of the observational part of the study is to look for variations in swallowing in adults with obstructive sleep apnea (OSA) and in adults who…
- Trial name
- SLP-PAP (NCT06786117)
- Testing
- SLP swallowing exercises, myofunctional exercises
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Denise Dewald
Head and Neck Cancer, Stroke
Real-Time Internet Evaluation of Swallowing
The purpose of this study is to determine whether real-time internet evaluations of swallowing, or x-ray swallow studies viewed over closed internet circuit, are a reliable method of evaluating swallowing function.
- Trial name
- NCT00580138
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Oesphageal Cancer, Para-conduit Hernia
The PHARO Trial: The Incidence of Para-conduit Hernia With Closure of Hiatus Versus the Standard Approach in Robotic Oesophagectomy - A Randomised Controlled Pilot Trial
Para-conduit hernia is a recognised complication following minimally invasive and robotic oesophagectomy. It may present as an incidental radiological finding or as a symptomatic hernia requiring urgent surgical intervention.
- Trial name
- PHARO (NCT07426835)
- Testing
- Standard Hiatal Management, Hiatal Closure With Omentopexy and Left Crus Fixation
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Royal College of Surgeons, Ireland
Oropharyngeal Dysphagia
Autologous Muscle Derived Cells for Treatment of Tongue Dysphagia
The primary objective of this double-blind, randomized, placebo-controlled, multicenter clinical trial is to evaluate the safety of AMDC-GIR during the 24 months following 2 consecutive treatments of tongue dysphagia in male and…
- Trial name
- REVIVE (NCT05421689)
- Testing
- Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR)
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of California, Davis
Erosive Reflux Disease, Heartburn
Observationa Study is a Prospective and Multi-institutional Observational Study.
This observational study is a prospective, multi-institutional non intervention study to examine the prescription patterns, corresponding treatment effects and safety in routine clinical practice for patients prescribed for the…
- Conditions
- Erosive Reflux Disease, Heartburn, Acid Regurgitation
- Trial name
- NCT06952855
- Where
- South Korea
- Volunteers
- 5,536 people
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
GERD
PPI Test in GP Patients
The purpose of this study is to determine the diagnostic value of two week treatment with Nexium as a confirmatory test for patients with suspected reflux disease.
- Trial name
- NCT00318084
- Testing
- Esomeprazole, Ambulatory 24-hour esophageal pH-monitoring
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
GERD, Hiatal Hernia
Long-term Follow-up After Hiatal Hernia Repair by Tension-free Mesh Closure or Simple Suturing
10 years of follow-up after surgery for hiatal hernia by tension-free mesh closure or simple suturing.
- Conditions
- GERD, Hiatal Hernia, Dysphagia, Esophageal, Quality of Life
- Trial name
- NCT05069493
- Testing
- simple suturing, mesh
- Where
- Sweden
- Volunteers
- 103 people
- Sponsor
- Karolinska University Hospital
Oropharyngeal Dysphagia, Stroke
Treatment of Chronic Post-stroke Oropharyngeal Dysphagia With Paired Stimulation
According WHO, oropharyngeal dysphagia (OD) is a prevalent post-stroke (PS) condition involving the digestive system (ICD-10: I69.391) and an independent risk factor for malnutrition and pulmonary infection; and leads to greater…
- Conditions
- Oropharyngeal Dysphagia, Stroke, Stroke, Complication, Swallowing Disorder
- Trial name
- ICI20/00117 (NCT05720871)
- Testing
- rTMS + capsaicin 150μM (natural TRPV1 agonist), tDCS + capsaicin 150μM (natural TRPV1 agonist)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital de Mataró
Gastroesophageal Reflux Disease
Gastric Accommodation and Gastroesophageal Reflux
Gastroesophageal reflux events generally happen during relaxation of lower esophageal sphincter. This relaxation is a reflex that is triggered by gastric stimuli.
- Trial name
- NCT01078064
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nationwide Children's Hospital
Gastroesophageal Reflux Disease (GERD)
Post-Market Registry for the Evaluation of RefluxStop in GERD Treatment
This post-market registry aims to assess safety and performance of RefluxStop™ in the treatment of Gastroesophageal Reflux Disease (GERD) in standard of care procedures.
- Trial name
- NCT05870163
- Testing
- RefluxStop implantation, Nissen fundoplication
- Where
- 6 sites in Germany, Italy and 2 more
- Volunteers
- 2,500 people
- Sponsor
- Implantica CE Reflux Ltd.
Dysphagia, Esophageal
Esophageal Impedance and Manometry Measurements and Dysphagia Symptom Scoring
Comparison of manometry measurements and EndoFlip Balloon measurements in patients with dysphagia and a known esophageal diagnosis
- Trial name
- NCT04503785
- Testing
- Manometry
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Indiana University
GERD
Effectiveness of Diaphragmatic Breathing on Reflux Symptoms in Outpatients
Researchers are trying to determine if abdominal breathing exercises can reduce symptoms associated with GERD (Gastroesophageal reflux disease).
- Trial name
- NCT04120025
- Testing
- Diaphragm Training
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Mayo Clinic
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