Clinical trials: Deglutition Disorder
Swallowing-induced Pain
Doxepin Solution for Alleviation of Stubborn Breakthrough Pain Induced by Swallowing in Patients Receiving Radiotherapy for Nasopharyngeal Carcinoma
The goal of this clinical trial is to explore the effectiveness and adverse reactions of doxepin solution spray for alleviation of stubborn breakthrough pain induced by swallowing in patients receiving radiotherapy for…
- Trial name
- NCT06017895
- Testing
- doxepin solution
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Perforation Esophagus, Esophageal Cancer
Feasibility and Efficacy of a Combination of a SEMS and Vacuum Wound Treatment (VACStent)
Open, prospective, one-arm feasibility and efficacy study of a European conformity (CE) certified Combination product of two CE certified medical devices in the intended indication.
- Conditions
- Perforation Esophagus, Esophageal Cancer, Esophageal Achalasia, Esophageal Diseases
- Trial name
- VACStent (NCT03962179)
- Testing
- VACStent
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital of Cologne
Eosinophilic Esophagitis
Esophageal Motility in Eosinophilic Esophagitis Evaluated by High Resolution Manometry.
Esophageal Motility in eosinophilic esophagitis will be evaluated by High Resolution Manometry before and after medical treatment - motility is suspected to change/improve after therapy.
- Trial name
- HIMEOS (NCT02331849)
- Testing
- High resolution manometry (HRM)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Gastroesophageal Reflux
MSG and Gastrointestinal Motility
The purpose of this study is to clarify the physiological function of sodium glutamate by measuring its effect on upper GI motility ( gastric emptying).
- Trial name
- NCT01009658
- Testing
- Monosodium glutamate, Sodium chloride
- Where
- Japan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gunma University
Post-extubation Dysphagia
Clinical Application of Comprehensive Intervention for PED Based on Neuroregulatory Mechanism
This study aims to establish a practical comprehensive intervention program for dysphagia after extubation in adult ICU patients based on the best evidence of its assessment and intervention, through expert panel discussion and…
- Trial name
- NCT06386159
- Testing
- Comprehensive Intervention or Comprehensive Intervention Combined with Electrical vagus nerve stimulation
- Where
- China
- Volunteers
- 69 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Dysphagia, Cardiovascular Diseases
Dysphagia and Vocal Cord Injury Following Cardiac Surgery
Aiming to determine the incidence and contributing risk factors of vocal fold mobility impairment (VFMI) and dysphagia in postoperative cardiovascular patients and evaluate the impact of VFMI on health-related outcomes.
- Trial name
- NCT04464317
- Sponsor
- University of Florida
Parkinson's Disease, Dysphagia
Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial
Currently, there are no efficacious behavioral treatment approaches to address uncompensated aspiration, or aspiration without appropriate cough response, in Parkinson's disease (PD).
- Conditions
- Parkinson's Disease, Dysphagia, Dystussia
- Trial name
- NCT02927691
- Testing
- EMST, smTAP
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Teachers College, Columbia University
Swallowing Disorder, Validation
Validity and Reliability of the Turkish Translation of the Yale Pharyngeal Residue Severity Rating Scale
Purpose of the study is the validity and reliability of the Turkish version of the Yale Pharyngeal Residue Severity Rating Scale (YPRSRS-T), so that it would be used as an assessment tool for dysphagia patients.
- Conditions
- Swallowing Disorder, Validation, Pharyngeal Dysphagia
- Trial name
- NCT04477174
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Mitral Valve Regurgitation
Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System
The purpose of this study is to evaluate the safety and initial performance of the Neovasc Tiara Mitral Transcatheter Heart Valve with the Tiara Transapical Delivery System.
- Trial name
- TIARA-I (NCT02276547)
- Testing
- Mitral valve replacement
- Where
- 10 sites in United States, Belgium and 1 more
- Volunteers
- 27 people
- Sponsor
- Shockwave Medical, Inc.
Dysphagia, Dysphagia, Esophageal
Per-oral Endoscopic Myotomy (POEM) in Patients with Postfundplication Dysphagia
Laparoscopic fundoplication represents the standard antireflux procedure, when conservative measures fail. However, any type of fundoplication may be accompanied by adverse events.
- Conditions
- Dysphagia, Dysphagia, Esophageal, Healthy
- Trial name
- VADYSMA (NCT06872255)
- Testing
- Per Oral Endoscopic Myotomy (POEM)
- Where
- 2 sites in Czechia, Slovakia
- Volunteers
- 30 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Acupuncture, Dysphagia
Efficacy and Mechanism of 'Yanjiu Needle' for Pharyngeal Dysphagia Based on sEMG Features
Dysphagia is one of the most common and serious complications following stroke. It can easily lead to aspiration and aspiration pneumonia, reduce patients' quality of life, increase healthcare costs, and result in high mortality…
- Conditions
- Acupuncture, Dysphagia, Surface EMG
- Trial name
- NCT07656025
- Testing
- Yanjiu Acupuncture, a three-point acupuncture technique, control group
- Volunteers
- 100 people
- Sponsor
- The Third People's Hospital of Huizhou
Head and Neck Cancer, Dysphagia
A Pilot Study of ALTENS in Improving Dysphagia Induced by IMRT for Head and Neck Cancers
Study hypothesis: ALTENS techniques, administered within the first 3 months after radiation completion, can improve radiation-induced dysphagia and associated symptoms in head and neck cancer patients.
- Trial name
- NCT01697891
- Testing
- Codetron ALTENS
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- McMaster University
Dysphagia
Nutrition-dense Smoothie Diets Reduced Dysphagia Risk in the Elderly
The investigators aimed to compare the effect of consuming high protein (23-34% energy ratio) and low carbohydrate (25-38% energy ratio) smoothie formulas vs.
- Trial name
- NCT04901182
- Testing
- the effect of consuming diets on the swallowing capacity by using Flexible Endoscopic Evaluation of Swallowing (FEES)
- Where
- Thailand
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Breast Cancer Female, Dysphagia
Zinc-L-Carnosine Prevents Dysphagia in Breast Cancer Patients Undergoing Adjuvant Radiotherapy
Irradiation of level III and IV draining nodes in breast cancer patients is often associated with dysphagia, requiring treatment with FANS and/or steroids.
- Conditions
- Breast Cancer Female, Dysphagia, Adjuvant Radiotherapy
- Trial name
- NCT03997188
- Testing
- Hepilor
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Cynthia Aristei
Head and Neck Cancer, Stage I Hypopharyngeal Cancer
Effects of Swallowing Exercises on Patients Undergoing Radiation Treatment for Head and Neck Cancer
RATIONALE: Swallowing exercise therapy may improve the quality of life of head and neck cancer patients undergoing chemotherapy or radiation therapy.
- Conditions
- Head and Neck Cancer, Stage I Hypopharyngeal Cancer, Stage I Laryngeal Cancer, Stage I Oropharyngeal Cancer
- Trial name
- NCT01053546
- Testing
- exercise intervention, questionnaire administration, quality-of-life assessment
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Wake Forest University Health Sciences
Sleep Apnea, Hypertension
Tri Staple Technology Stapler Used in Gastric Bypass
The objectives of this clinical trial are to assess in a pilot setting the overall performance and safety of the Endo GIA™ Stapler with Endo GIA™ SULU with Tri-Staple™ Technology when used in a gastric bypass procedure.
- Conditions
- Sleep Apnea, Hypertension, Hyperlipidemia, Coronary Artery Disease
- Trial name
- NCT01026103
- Testing
- Tri Staple Technology stapler
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Gastroesophageal Reflux, Heartburn
Esomeprazole and Gastric Emptying of Beer
To investigate the effect of 20 mg esomeprazole daily for one week on gastric emptying of 500 ml beer, the consecutive blood alcohol levels, the gastroesophageal reflux and plasma levels of gastrin and CCK in a randomized…
- Trial name
- NCT00472550
- Testing
- esomeprazole 20 mg
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Gastroesophageal Reflux Disease
A Prospective Randomized Trial Comparing Laparoscopic Nissen Against Anterior Partial Fundoplication in Treating Gastroesophageal Reflux Disease Among Chinese Patients
The aim of this study is to compare the effectiveness of laparoscopic Nissen against anterior partial fundoplication in the control of gastroesophageal reflux disease among Chinese patients Study hypothesis Laparoscopic Nissen is…
- Trial name
- NCT00480285
- Testing
- Laparoscopic Nissen Fundoplication, Laparoscopic anterior partial fundoplication
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
GERD, Reflux Esophagitis
A Novel Endoloop Pre-test to Treat Gastroesophageal Reflux
The purpose of this study was to evaluate the safety and efficacy of endoscopic endoloop pre-test for gastroesophageal reflux before anti-reflux surgery or endoscopic treatment.
- Trial name
- NCT05192538
- Testing
- Endoscopic endoloop pre-test treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.