Clinical trials: Deglutition Disorder
Deglutition Disorders, Swallowing Disorder
Validation of BRACS to European Portuguese
The goal of this observational study is to translate and validate the fiberoptic endoscopic evaluation of swallowing scale "The Boston Residue and Clearance Scale - BRACS" to European Portuguese
- Conditions
- Deglutition Disorders, Swallowing Disorder, Dysphagia, Oropharyngeal
- Trial name
- NCT06558435
- Testing
- FEES
- Where
- Portugal
- Volunteers
- 16 people
- Sponsor
- Centro Hospitalar de Entre o Douro e Vouga
Non-erosive Reflux Disease (NERD)
Transcutaneous Electrical Acustimulation (TEA) for the Treatment of Non-Erosive Gastroesophageal Reflux Disease (NERD)
This multicenter study aims to evaluate whether Transcutaneous Electrical Acustimulation (TEA) is effective in treating Non-Erosive Gastroesophageal Reflux Disease (NERD).
- Trial name
- NCT07572708
- Testing
- Transcutaneous Electrical Acustimulation
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Dysphagia, Dysphonia
The Effect of IV NSAID's and Corticosteroids on Dysphasia and Dysphonia Following ASDF
This study is to assess the efficacy of intra-operative intravenous non-steroidal anti-inflammatory drug (Ketorolac) versus intravenous (dexamethasone) administration on dysphagia and dysphonia after anterior cervical discectomy…
- Trial name
- NCT04650893
- Testing
- Intravenous Ketorolac, Intravenous Dexamethasone
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Healthy Volunteers
A Study to Determine the Bioavailability of Vonoprazan Sprinkle Capsules on Pudding or on Applesauce Relative to a Vonoprazan Tablet in Healthy Participants
The primary objective of this study is to assess the bioavailability (BA) of a single oral dose of vonoprazan 20 mg sprinkle capsule, either sprinkled on pudding or on applesauce, relative to a vonoprazan 20 mg tablet in healthy…
- Trial name
- NCT05366738
- Testing
- Vonoprazan
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Phathom Pharmaceuticals, Inc.
Gastroesophageal Reflux Disease, Hiatal Hernia
Transoral Incisionless Fundoplication (TIF) Registry Study for Treatment of Gastroesophageal Reflux Disease (GERD)
The study objective is to evaluate the safety and efficacy of TIF among a broad range of GERD patients treated in routine clinical practice at multiple centers across the United States.
- Trial name
- NCT01118585
- Testing
- TIF Procedure
- Where
- 14 sites in United States
- Volunteers
- 278 people
- Sponsor
- EndoGastric Solutions
Gastrointestinal Disease, Gastrointestinal Disorders
Telehealth-Delivered Gut-Directed Hypnotherapy for Managing GI Health
This study aims to evaluate the specific and non-specific effects of hypnotherapy and to evaluate the efficacy of group-format gut-directed hypnotherapy (GDH) delivered via telehealth for managing gastrointestinal health.
- Conditions
- Gastrointestinal Disease, Gastrointestinal Disorders, Nervous System
- Trial name
- NCT06890663
- Testing
- Nonspecific Hypnotherapy for Relaxation, Gut-Directed Hypnotherapy (GDH), 3-month Follow-Up
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Central Florida
Obesity, Obesity, Abdominal
Laparoscopic Clip-Gastroplasty With The Use Of Bariclip
Sleeve gastrectomy, the most commonly performed bariatric surgery procedure, carries limitations both short-term including postoperative complications such as hemorrhage and gastric fistula and long-term such as weight regain and…
- Conditions
- Obesity, Obesity, Abdominal, Surgery
- Trial name
- B-Clamp (NCT05557084)
- Testing
- laparoscopic vertical clip gastroplasty (LVCG) with Bariclip.
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Rome Tor Vergata
Cough, COPD
Acoustic Cough Monitoring for the Management of Patients With Known Respiratory Disease
This study pretends to evaluate the potential use of Hyfe Cough Tracker (Hyfe) to screen for, diagnose, and support the clinical management of patients with respiratory diseases, while enriching a dataset of disease-specific…
- Conditions
- Cough, COPD, GERD, Asthma
- Trial name
- NCT05042063
- Testing
- Hyfe Cough Tracker, Hyfe Air
- Where
- Spain
- Volunteers
- 616 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Deglutition Disorder
Effect of Different Viscous Foods and Liquids on Swallowing Sounds
This study is aimed to establish and identify the normal pattern of swallowing sounds and analyze swallowing sounds of different textured foods and viscous liquids in healthy subjects to provide clinical evidence to update…
- Trial name
- NCT03024333
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Deglutition Disorders
The Accuracy of Swallowing Disturbance Questionnaire in Screening Inpatient Elderly
The aim of this research was to examine the accuracy of translated Chinese version of Swallowing Dysphagia Questionnaire and to evaluate the prevalence of dysphagia and its clinical manifestation in patients over 65 years old.
- Trial name
- NCT03816098
- Volunteers
- 40 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Gastroesophageal Reflux Disease, Obesity
Reflux Disease After Gastric Bypass Versus Sleeve Gastrectomy in Morbid Obese Patients: an Italian Study
The study aims to clarify if GERD, defined by results of 24 hours potential of hydrogen (pH) monitoring and abnormal DeMeester Score (DMS), in obese patients could worsen after Sleeve Gastrectomy (SG) more than after RYGBP.
- Trial name
- ReBvSS (NCT04763993)
- Testing
- Roux-en-Y-Gastric bypass, Sleeve gastrectomy, SG
- Volunteers
- 128 people
- Sponsor
- Niguarda Hospital
Gastroesophageal Reflux Disease
The Effect of Lansoprazole in Combination With Ecabet Sodium for Gastroesophageal Reflux Disease
We will estimate the responses of lansoprazole and ecabet sodium combination therapy and compare with lansoprazole and placebo therapy in patients who need additional therapy after standard proton pump inhibitor treatment for…
- Trial name
- NCT01039558
- Testing
- ecabet sodium, lansoprazole
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Niemann-Pick Disease, Type C
VTS-270 to Treat Niemann-Pick Type C1 (NPC1) Disease
Due to different study designs, the sponsor separated Part C into a separate registration (NCT04958642), leaving Parts A/B here in NCT02534844.
- Trial name
- NCT02534844
- Testing
- Parts A/B: Adrabetadex
- Where
- 29 sites in United States, Australia and 7 more
- Volunteers
- 56 people
- Sponsor
- Mandos LLC
Eosinophilic Esophagitis
The Role of HRM and Specific Biomarkers of Inflammation in the Diagnosis of Patients With Dysphagia and Suspected EoE
The aim of the project is to assess the correlation between the results of high-resolution oesophageal manometry and specific biomarkers of inflammation (eotaxin 3, major basic protein, IL-5, IL-13, TGF-beta1) with symptoms of…
- Trial name
- NCT04803162
- Testing
- High-resolution manometry, Serum biomarkers, Gastrointestinal Quality of Life index
- Where
- Poland
- Volunteers
- 58 people
- Sponsor
- Wroclaw Medical University
Cerebral Palsy
Efficacy of Lidocaine Block in Children With Cerebral Palsy and Dysphagia
The goal of this clinical trial is to test the efficacy of stellate ganglion block in children with cerebral palsy and dysphagia.
- Trial name
- NCT06304090
- Testing
- routine rehabilitation treatment, Stellate ganglion block, Lidocaine Hydrochloride
- Volunteers
- 80 people
- Sponsor
- Muhammad
Achalasia
Sensorimotor Dysfunction in Achalasia
This study is being done to assess the esophageal muscle (swallowing tube) in patients with and without achalasia to further understand and help direct the treatment for patients with achalasia.
- Trial name
- NCT02434991
- Testing
- Barostat
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Copd, Heart Failure
The Effect of Using Virtual Reality Glasses on Post-Care Pain and Comfort Level in Intensive Care Patients
The aim of this study is to determine the level of pain and comfort associated with the implementation of virtual reality prior to nursing care in patients undergoing treatment in the intensive care unit.
- Conditions
- Copd, Heart Failure, Intensive Care Unit Syndrome, Renal Failure
- Trial name
- NCT06923982
- Testing
- virtual reality, experimental group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Dysphagia, Cardiovascular Diseases
Dysphagia and Vocal Cord Injury Following Cardiac Surgery
Aiming to determine the incidence and contributing risk factors of vocal fold mobility impairment (VFMI) and dysphagia in postoperative cardiovascular patients and evaluate the impact of VFMI on health-related outcomes.
- Trial name
- NCT04464317
- Sponsor
- University of Florida
Stroke
Coughing in Infratentorial Brain Lesion Patients
To record diaphragm excursion in infratentorial brain lesions patients with dysphagia during coughing and compare them to those with supratentorial brain lesion patients with dysphasia and those with no dysphagia at a university…
- Trial name
- NCT02081040
- Testing
- Not applicable (observational study with no active intervention)
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- The Catholic University of Korea
Dysphagia
Effect of Computer-based Cognitive Function Training on Cognitive Dysphagia After Stroke
This is a multicenter randomized controlled study. The study recruited stroke patients with mild cognitive impairment and dysphagia who were undergoing inpatient rehabilitation treatment in three hospitals in mainland China as…
- Trial name
- NCT06303882
- Testing
- routine rehabilitation treatment, Computer-assisted Cognitive Function Training, conventional cognitive training
- Volunteers
- 80 people
- Sponsor
- Muhammad
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