Clinical trials: Deglutition Disorder
Chronic Use of Acid Suppressive Medication, GORD
On-Demand Use of Pantoprazole: Determinants for Chronic Use of Acid Suppressive Medication
The purpose of this study is to investigate several aspects of chronic use of acid suppressing medication: dependence on maintenance therapy, the possibilities for on-demand use, and predictors (patient characteristics) for daily…
- Conditions
- Chronic Use of Acid Suppressive Medication, GORD, GERD, Reflux
- Trial name
- NCT00161096
- Testing
- pantoprazole 20 mg (drug)
- Volunteers
- 276 people
- Sponsor
- UMC Utrecht
GERD, Healthy
[Impedance Measurement for Non-Erosive Reflux Disease
This study is being done to determine if people with and without GERD or trouble swallowing have increased esophageal mucosa impedance (food getting into the esophageal tissue).
- Trial name
- Impedance (NCT02997527)
- Testing
- Intraluminal Impedance
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Non-erosive Reflux Disease(NERD)
Clinical Trial to Evaluate the Efficacy and Safety of EsoDuo Tab. 20/800mg
To Evaluate the Efficacy and Safety of EsoDuo Tab. 20/800mg
- Trial name
- NCT03928470
- Testing
- EsoDuo Tab. 20/800mg
- Where
- 38 sites in South Korea
- Volunteers
- 379 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Barrett Esophagus
A Minimally-Invasive Sponge on a String Device for Screening for Barrett's Esophagus
This study is being done to collect data on the potential use of a sponge on a string device as a non-invasive tool in evaluating patients with Barrett's Esophagus compared to healthy controls.
- Trial name
- NCT02560623
- Testing
- Biopsy, Biospecimen Collection, Endoscopic Procedure
- Where
- 6 sites in United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gastroesophageal Reflux Disease
The Difference of Reflux Pattern Between the Patients Who Have Postprandial Reflux Symptoms
Gastroesophageal reflux disease is increasing worldwide. The causes of reflux symptoms are not found exactly. especially, the postprandial reflux symptoms are more common than the all day reflux symptoms.
- Trial name
- NCT02154659
- Testing
- 24hr pH monitoring
- Where
- South Korea
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Dysphagia, Non-Small Cell Lung Cancer
Study to Evaluate Palifermin in the Reduction of Dysphagia in Patients With Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
The purpose of this study is to determine if palifermin will reduce the incidence of dysphagia in patients receiving concurrent chemoradiotherapy followed by consolidation chemotherapy for treatment of unresectable stage III…
- Conditions
- Dysphagia, Non-Small Cell Lung Cancer, Lung Cancer
- Trial name
- NCT00094861
- Testing
- Palifermin, Radiotherapy, Paclitaxel
- Volunteers
- 100 people
- Sponsor
- Swedish Orphan Biovitrum
Post-extubation Dysphagia
Post-extubation Dysphagia
Mechanical ventilation is a widely used treatment on the Intensive Care Unit (ICU). Swallowing dysfunction (dysphagia) after extubation may cause aspiration, and is associated with poor outcomes: pneumonia, reintubation, a…
- Trial name
- NCT03761823
- Where
- Netherlands
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Gastroesophageal Reflux Disease
Maintenance Intermittent Therapy for Symptomatic GERD Patients
The purpose of this study to determine the efficacy of 20 mg of rabeprazole given as a maintenance intermittent therapy following acute treatment for Symptomatic Gastroesophageal Reflux Disease (s-GERD).
- Trial name
- NCT00165841
- Testing
- Rabeprazole 20 mg
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Eisai Inc.
Gastroesophageal Reflux Disease
Effect of Lidocaine Block on Gastroesophageal Reflux Disease
The goal of this clinical trial is to explore Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux Disease. The main question it aims to answer is: Can stellate ganglion block improve gastroesophageal reflux…
- Trial name
- NCT06304142
- Testing
- Rehabilitation therapy, Injection, Lidocaine hydrochloride
- Volunteers
- 80 people
- Sponsor
- Muhammad
Gastroesophageal Reflux Disease (GERD), Heartburn
Response to Supplement and Placebo in GERD
The purpose of this study is to investigate the effects of a widely available over the counter supplement marketed for heartburn symptoms on symptoms and health-related quality of life in patients with gastroesophageal reflux…
- Conditions
- Gastroesophageal Reflux Disease (GERD), Heartburn, Dyspepsia
- Trial name
- NCT01915173
- Testing
- Supplement, Expanded Interview, Standard Interview
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Beth Israel Deaconess Medical Center
Gastroesophageal Reflux
Open Label Safety Study of Enteric-Coated Spheroid Suspension in Infants Aged Less Than 12 Months With Presumed Gastroesophageal Reflux Disease (GERD)
The purpose of this study is to provide additional information on safety and tolerability after multiple does of pantoprazole. Only patients who successfully completed the 3001B3-331 study (NCT00362609) or 3001B3-333 study…
- Trial name
- NCT00868296
- Testing
- pantoprazole
- Where
- 71 sites in United States, Australia and 9 more
- Volunteers
- 58 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
GERD
Electrical Stimulation Therapy (EST) of the Lower Esophageal Sphincter (GERD)
The investigational device that will be used in this trial is the EndoStim® Lower Esophageal Sphincter (LES) Stimulation System.
- Trial name
- EST-SHAM-EUR (NCT02514616)
- Testing
- Laparoscopic IPG and lead implant procedure, Active Electric Stimulation Therapy, Delayed Electric Stimulation Therapy
- Where
- 2 sites in Belgium, France
- Volunteers
- 1 people
- Sponsor
- Erasme University Hospital
Gastroesophageal Reflux Disease
Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD)
GERD is due to gastric content reflux to esophagus cause symptom and complication including intra-esophagus such as reflux esophagitis, and extra-esophagus such as cough etc.
- Trial name
- NCT01822106
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- China Medical University Hospital
Dysphagia
Computer-based Training on Cognitive Dysphagia in Stroke Survivors
This is a multicenter randomized controlled study. The study recruited stroke patients with mild cognitive impairment and dysphagia who were undergoing inpatient rehabilitation treatment in three hospitals in mainland China as…
- Trial name
- NCT06328816
- Testing
- routine rehabilitation treatment, Computer-assisted Cognitive Function Training
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Dysphagia
Esophageal Calibration During Laparoscopic Fundoplication Reduces Dysphagia
Gastro esophageal reflux is the most common benign disease of the esophagus and Laparoscopic Nissen fundoplication became the standard surgical treatment of this disease.
- Trial name
- NCT01501071
- Testing
- Esophageal calibration tube
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Antalya Training and Research Hospital
Alzheimer Disease
Intermittent Oral-esophageal Tube Feeding in Alzheimer's Patients With Dysphagia
This is a prospective multicenter study with Alzheimer's patients with dysphagia. Patients enrolled are randomly divided equally into the observation group and the control group.
- Trial name
- NCT06220292
- Testing
- Conventional Care, Intermittent Oral-esophageal Tube Feeding, Nasogastric tube
- Where
- China
- Sponsor
- Zeng Changhao
Gastroparesis
Idiopathic Gastroparesis Registry Using a Predominant-Symptom Classification
The diagnosis of "gastroparesis" suggests that delayed gastric emptying is the underlying cause of symptoms, but this description fails to explain the variable presentation.
- Trial name
- NCT01173484
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Louisville
Gastroesophageal Reflux
Efficacy of Pantoprazole in Patients Older Than 18 Years Who Have Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-339)
Gastroesophageal reflux disease (GERD) is a medical condition affecting the stomach and esophagus. GERD occurs when the lower esophageal sphincter does not close properly and stomach contents leaks back (refluxes) into the…
- Trial name
- NCT00163306
- Testing
- Pantoprazole
- Where
- 79 sites in Austria, Germany and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Takeda
Dysphagia
Effect of Training of Patients With Dysphagia
Effect of training of patients with dysphagia
- Trial name
- NCT04402307
- Testing
- Chin Tuck Against Resistance
- Where
- 8 sites in Denmark
- Volunteers
- 93 people
- Sponsor
- Regionshospital Nordjylland
Gastro Oesophageal Reflux Disease
Influence of Wrap Fixation Technique on the Results of Fundoplication
Patients who underwent anti-reflux surgery were divided into two groups. In the I group Nissen fundoplication was supplemented with suturing wrap to the crura or the body of stomach using two non-absorbable stitches on each side.
- Trial name
- NCT04335734
- Testing
- Nissen Fundoplication with wrap fixation, Nissen Fundoplication without wrap fixation
- Volunteers
- 138 people
- Sponsor
- Grubnik Volodymyr
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