Clinical trials: Dehiscence, Surgical Wound
Laparoscopic Surgery
Clinical Trial of MedLogic LiquiBand Laparoscopic Versus Dermabond in the Closure of Surgical Incisions
To evaluate the effectiveness, safety, and utility of LiquiBand Laparoscopic™ in relation to a currently approved active control product (High Viscosity DermaBond).
- Trial name
- NCT00762905
- Testing
- LiquiBand Laparoscopic, Dermabond
- Where
- 4 sites in United Kingdom
- Volunteers
- 460 people
- Sponsor
- MedLogic Global Limited
Wound Infection, Incisional Hernia
When Closing Midline Incisions, do Small Stitches Reduce the Risk for Incisional Hernia, Wound Infection or Dehiscence?
The purpose of this study is to determine whether a technique using very small stitches when closing a midline incision can reduce the risk for wound complications such as incisional hernia, infection or dehiscence.
- Conditions
- Wound Infection, Incisional Hernia, Wound Dehiscence
- Trial name
- NCT00508053
- Testing
- Small stitches, Mass closure
- Where
- Sweden
- Volunteers
- 737 people
- Sponsor
- Sundsvall Hospital
Wound Dehiscence, Surgical
The Comparison of Interrupted Modified Smead-Jones Versus Conventional Continuous Suturing Technique for Closure of Rectus Sheath in Patients Undergoing Laparotomy for Hollow Viscus Perforation.
After taking approval from Board of Studies, IRB \& ASRB of KEMU, 108 patients fulfilling inclusion criteria will be admitted in Department of General Surgery, East Surgical Ward, Mayo Hospital Lahore through Emergency…
- Trial name
- Farrukh 24 (NCT06697067)
- Testing
- modified smead jones, conventional comtinuous suture techniques
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- King Edward Medical University
Incisional Hernia, Wound Dehiscence
Hernia After Colorectal Cancer Surgery
Defects in the abdominal wall (incisional hernia) is a frequent negative outcome after surgery. Reinforcing the incision with mesh seem to lower the incidence but in surgery that includes bowel resection a simple alternative…
- Conditions
- Incisional Hernia, Wound Dehiscence, Wound Complication, Quality of Life
- Trial name
- Rein4CeTo1 (NCT03390764)
- Testing
- 4:1 closure group, RTL plus 4:1 closure group
- Where
- Sweden
- Volunteers
- 152 people
- Sponsor
- Skane University Hospital
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Fibrolipoma of Filum Terminale, Lipomyelomeningocele
Effect of Acetazolamide & Position in CSF Leakage and Collection and Wound Dehiscence
Purpose of study : to determine the preventive effect of acetazolamide administration, prone positioning, and the combination of both following the neurosurgical interventions in lumbosacral region for cerebrospinal fluid (CSF)…
- Conditions
- Fibrolipoma of Filum Terminale, Lipomyelomeningocele, Split Cord Malformation, Dermal Sinus
- Trial name
- NCT01867268
- Testing
- Acetazolamide, prone positioning, Acetazolamide+ prone positioning
- Where
- Iran
- Volunteers
- 144 people
- Sponsor
- Tehran University of Medical Sciences
Cesarean Section; Dehiscence
A Randomized Clinical Study Based on Comparison Between Closure of Uterine Incision With Vicryl 2/0 Versus Vicryl 1 in Development of Uterine Niche.
The first group patients underwent double layer closure with split thickness with vicryl 2/0, in continuous, non- locked, 1 cm apart sutures, study group, and the second group, women underwent double layer closure with split…
- Trial name
- NCT05770115
- Testing
- Vicryl 1, Vicryl 2/0
- Where
- Egypt
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgical Wound Dehiscence
Vaginal Cuff Dehiscence Following Total Laparoscopic Hysterectomy: Laparoscopic vs. Transvaginal Cuff Closure
Post-hysterectomy vaginal cuff dehiscence is a rare but threatening complication. The investigators will compare transvaginal versus laparoscopic closure of the vaginal vault at the end of a total laparoscopic hysterectomy, in…
- Trial name
- NCT02453165
- Testing
- TRANSVAGINAL SUTURE, LAPAROSCOPIC SUTURE
- Where
- Italy
- Volunteers
- 1,408 people
- Sponsor
- Università degli Studi dell'Insubria
Colorectal Cancer
Interrupted 'Figure-of-X' Versus Continuous Suturing Technique for Abdominal Wall Closure in Colorectal Laparotomies
This prospective randomized comparative study aims to evaluate whether interrupted figure-of-X fascial closure reduces the incidence of burst abdomen compared with continuous suturing in patients undergoing open colorectal…
- Trial name
- X-CLOSURE (NCT07585344)
- Testing
- Interrupted 'Figure-of-X' Suturing Technique, CONTINUOUS AMSS CLOSURE
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Islamabad Medical and Dental College
Surgical Wound Infection, Cesarean Wound; Dehiscence
Sucrose as a Standard in Cesarean Section Surgical Wound Healing to Reduce Hospital Time
It is a randomized, single-blind clinical trial, whose population to be studied will be randomized patients with a diagnosis of dehiscence and infection of a cesarean surgical wound who meet the inclusion and exclusion criteria.
- Trial name
- SAGRA (NCT06477770)
- Testing
- Clorhexidine soap, Sucrose
- Where
- Honduras
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Suture Techniques, Wound Closure Techniques
Small Bites Vs Large Bites Abdominal Midline Incisional Closure
The goal of this trial is to compare the effectiveness of small bite versus large bite abdominal incision closure in emergency settings. It will also evaluate the safety and outcomes of each technique.
- Conditions
- Suture Techniques, Wound Closure Techniques, Laparotomy/Standerds, Surgical Wound Dehiscence
- Trial name
- NCT07154277
- Testing
- Small bite closure, Large bite closure
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Dow University of Health Sciences
Hematoma Intracranial, Hydrocephalus
Subgaleal Drains in Decompressive Craniectomies
This research is about the use of subgaleal drains to prevent accumulation of blood under the skin in patients undergoing surgery to remove part of the skull(craniectomy) and its associated complications.
- Conditions
- Hematoma Intracranial, Hydrocephalus, Surgical Site Infection, Wound Breakdown
- Trial name
- VADER (NCT03777774)
- Testing
- Passive Redon subgaleal drains, Vacuum Redon subgaleal drains, No Redon subgaleal drains
- Where
- 2 sites in Malaysia
- Volunteers
- 78 people
- Sponsor
- Universiti Sains Malaysia
Wounds and Injuries
Managing Wounds With Allevyn Life in a Home Health Care Environment
When elderly patients need help caring for wounds, physicians may refer patients to home health care providers. The home health provider sees the patient in the patient's home and assists the patient with wound care.
- Trial name
- NCT02776800
- Testing
- Allevyn Life, Foam dressing with an integrated adhesive border
- Where
- 3 sites in United States
- Sponsor
- Smith & Nephew, Inc.
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Wound Closure Technique, Wound Dehiscence, Surgical
Comparison of Cosmetic Outcome and Patient Satisfaction Between Staples and Suture Technique for Wound Closure Following Upper Limb Surgeries
Surgical wound closure is an essential component of postoperative care that influences wound healing, infection rates, cosmetic appearance, and patient satisfaction.
- Trial name
- NCT07633977
- Testing
- Staples, Sutures
- Where
- Nepal
- Volunteers
- 80 people
- Sponsor
- Kathmandu University School of Medical Sciences
Wound Dehiscence
Flipped Autograft for Treating Surgical Wound Dehiscence
This case report describes a novel technique for management of peri-implant wound dehiscence that involves using auto graft from the same surgical site to seal the dehiscence defect.
- Trial name
- NCT05513222
- Testing
- flipped autograft
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Abdominal Wound Dehiscence, Burst Abdomen
Vacuum-Assisted Closure Versus Graduated Primary Skin Closure for Postoperative Burst Abdomen
Burst abdomen, or complete abdominal wound dehiscence, is a severe postoperative complication characterized by the separation of the musculo-aponeurotic layer of the abdominal wall.
- Conditions
- Abdominal Wound Dehiscence, Burst Abdomen, Surgical Wound Dehiscence
- Trial name
- NCT07797868
- Testing
- Vacuum-Assisted Closure (VAC) Therapy, Graduated Primary Skin Closure
- Volunteers
- 50 people
- Sponsor
- Assiut University
Surgical Wound Dehiscence
Vaginal Cuff Dehiscence at Total Laparoscopic Hysterectomy
The aim of this study is to assess a major complication of total laparoscopic hysterectomy, vaginal dehiscence, with two different colpotomy techniques.
- Trial name
- NCT02879487
- Testing
- Monopolar needle electrode
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Wound and Injuries, Surgical Wound Dehiscence
The Clinical Efficacy of RENASYS TOUCH NPWT System in the Management of Acute, Sub-acute and Chronic Wounds
The study is looking at the clinical efficacy, functionality and device performance of a new Negative Pressure Wound Therapy (NPWT) system in the management of a variety of wound types, in a real-life clinical setting.
- Trial name
- NPWT (NCT02565043)
- Testing
- RENASYS TOUCH Negative Pressure Wound Therapy System
- Where
- 2 sites in South Africa
- Volunteers
- 80 people
- Sponsor
- Smith & Nephew, Inc.