Clinical trials: Dehydration (Physiology)
Aging, Dehydration
The Effect of Fluids Consumption on Balance and Gait Function in Old Adults
Experimental design overview The proposed project is a prospective experimental RCT study design. Independent old adults(age 65 years old and older) who do not suffer from balance problems willing to participate in the study will…
- Trial name
- NCT01181180
- Testing
- water consumption
- Where
- Israel
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Malnutrition Elderly, Kidney Diseases
Methods for Nutrition, Inflammation, Kidney Function, Aging, Body Composition, and Hydration Among Older Patients
The goal of this observational study, is to improve the diagnostic assessment method of malnutrition and kidney diseases, amongst hospitalized and low priority patients, by evaluating modern methodology and biomarkers, with…
- Conditions
- Malnutrition Elderly, Kidney Diseases, Dehydration
- Trial name
- MIKADO (NCT07501195)
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Ove Andersen
Hydration, Dehydration (Physiology)
The Role of Carbohydrate Blends and Electrolytes on Physical and Mental Performance During Cycling in the Heat
The aim of the present study is to evaluate the effectiveness of a milk permeate-based sports drink on hydration, carbohydrate oxidation, exercise performance, vigilance, and reaction time in the heat.
- Conditions
- Hydration, Dehydration (Physiology), Performance
- Trial name
- CARB-HEAT (NCT07658820)
- Testing
- Carbohydrate Milk Permeate sports drink, 6% Sports drink, Low-Carbohydrate Milk Permeate sports drink
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Dehydration (Physiology), Hyperthermia
Water Bolus Volumes During Continuous Exercise in Heat
Hydration is important to all individuals including occupational workers who complete physical activity in the heat. Current best practice guidelines suggest drinking a cup of water every 15-20 minutes during activity in a hot…
- Trial name
- NCT04613856
- Testing
- Hydration protocol - 237 mL water bolus, Hydration protocol - 500 mL water bolus
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Diarrhea
Slow Versus Rapid Rehydration of Severely Malnourished Children
The recommendation for correction of dehydration of severely malnourished children with diarrhoea includes oral rehydration and if parenteral rehydration is necessary (for example, in severe dehydration) to infuse intravenous…
- Trial name
- NCT02216708
- Testing
- Rapid dehydration, Slow rehydration
- Where
- Bangladesh
- Volunteers
- 208 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Dehydrated, Water-Electrolyte Imbalance, Malnutrition, Dehydration (Physiology)
Effects of Increased Water Intake on Hormonal Response, Hydration Status, and Physical Function in Low-drinking Older Adults
DrinkAge is a randomized controlled trial investigating whether increasing daily water intake can improve hydration and health-related outcomes in adults aged 60 years or older who habitually drink relatively little water.
- Trial name
- DrinkAge (NCT07892742)
- Testing
- Water
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Polytechnic University of Santarém
Dehydration, Dehydration (Physiology)
Adequate Hydration and Health Outcomes
Cardiovascular diseases (CVD) are the leading cause of death in middle- and high-income countries, according to data from the World Health Organization (WHO).
- Conditions
- Dehydration, Dehydration (Physiology), Glucose Abnormalities, Cardiovascular
- Trial name
- HYDRATE (NCT07179107)
- Testing
- Baseline - week 1, Low Water Intake - week 2, Moderate Water Intake - week 3
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Pancreatic Cancer
Personalised Nutritional Care in Older Patients With Pancreatic Ductal Adenocarcinoma
NutriCa65-PDAC is a clinical study for patients aged 65 years or older with pancreatic ductal adenocarcinoma, a type of pancreatic cancer.
- Trial name
- NutriCa65-PDAC (NCT07821554)
- Testing
- Experimental: Personalised nutritional care delivered by a trained dietitian
- Where
- 5 sites in Denmark, Italy and 3 more
- Volunteers
- 250 people
- Sponsor
- Inna Chen, MD
Fluid Retention, Sodium Retention
The Effect of AMP Human Sodium Bicarbonate Lotion on Dehydrated Heat Stress
The primary purpose of the proposed study is to evaluate the effects of a topical sodium bicarbonate lotion (PR Lotion, AMP Human, Park City, UT) on measures of hydration status and fluid balance in humans when exposed to the…
- Conditions
- Fluid Retention, Sodium Retention, Heat Stress, Dehydration (Physiology)
- Trial name
- AMP2 (NCT05092854)
- Testing
- PR Lotion - AMP Human Performance, AminoVital - Rapid Recovery
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Dehydration, Cognitive Change
The Effects of Hydration on Gut Health and Thinking
The central hypothesis is that improving hydration through increased water consumption will change the relative abundance of mucolytic bacteria found in the stool.
- Conditions
- Dehydration, Cognitive Change, Gastrointestinal Microbiota
- Trial name
- WatUP (NCT05315531)
- Testing
- Water Intake
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Aging
Dehydration, Rehydration, and Impact on Physiology
Our goal is to determine whether hydration status influences inflammation, and overall physiological performance in adults aged 45-65.
- Trial name
- DRIP (NCT07084675)
- Testing
- Hydration-Dehydration-Rehydration Protocol (HDR)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Prostate Cancer
Randomized AmnioFix Study During Radical Prostatectomy
The goal of this clinical research study is to learn about the safety and the effectiveness of using AmnioFix® (dehydrated human amnion/chorion membrane, also called dHACM) to help improve the return of erectile function and…
- Trial name
- NCT02645591
- Testing
- Robotic Assisted Laparoscopic Radical Prostatectomy (RARP), AmnioFix®, Questionnaire
- Sponsor
- M.D. Anderson Cancer Center
Dehydration
Hypohydration and Cardiorespiratory Function
Major non-cardiac surgery has a high degree of morbidity and mortality. Recently, measurement of a patient's preoperative cardiorespiratory reserve, performed non-invasively by cardiopulmonary exercise testing, has been shown to…
- Trial name
- NCT01949350
- Testing
- Carbohydrate, Carbohydrate protein, Starved
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Water Stress, Body Water Dehydration
Influence of Osmotic Stimulation of Vasopressin on Autonomic Function
The regulation of total body water that defines human hydration status is a complex and dynamic process. Current methods of assessing hydration status (e.g.
- Trial name
- NCT04233606
- Testing
- Hypertonic Saline, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Dehydration
Dehydration Cognition
The investigators want to understand the impact of the body losing and gaining water on brain function. Participants will restrict fluids consumed and exercise to lose 5% of body mass.
- Trial name
- NCT05916183
- Testing
- Fluid loss and consumption
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Dehydration Hypertonic, Isotonic Dehydration
Effects of Dehydration on Neuromuscular Performance and Sympathetic Control of Cardiovascular Function
The mechanism(s) by which dehydration (both intra- and extracellular) impairs performance are still poorly described. A loss of volume results in increased occurrence of orthostatic intolerance, including dizziness, fatigue…
- Trial name
- NCT03263975
- Testing
- Gatorade or Enterade
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Dehydration, Hyperhydration
Effects of Hydration Changes on Neuromuscular Function of Athletes
Greater muscular strength and power are relevant qualities for athletic success and decreased injury rate. It is known that dehydration impairs muscular strength and power, although the explanation for this association is not…
- Trial name
- H2OAthletes (NCT05380089)
- Testing
- Increasing water intake
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Dehydration (Physiology), Thirst; Due to Deprivation of Water
Patient Controlled Fluid Administration
The purpose of the study is to determine whether participants who are dictating their own administration of IV fluid boluses in response to thirst, receive better protection from hypovolaemia and volume overload than those who…
- Conditions
- Dehydration (Physiology), Thirst; Due to Deprivation of Water, Plasma Osmolality Increased, Hypovolemia
- Trial name
- NCT03176043
- Testing
- IV Fluid Administration
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University College, London
Dehydration (Physiology)
Dehydration and Population Health
The primary aim of this study is to assess cardiovascular changes (blood pressure, heart rate, electrocardiogram/ECG) in response to mild fluid-restriction dehydration and subsequent rehydration in healthy young and old people.
- Trial name
- NCT04502238
- Testing
- Fluid restriction
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wayne State University
Partial Nephrectomy, Kidney Cancer
Use of Human Dehydrated Amnion/Chorion (DHACM) Allograft in Partial Nephrectomy
After partial nephrectomy, kidney function decreases by about 10% overall and by about 20% in the operated kidney. This is primarily due to the loss of healthy parenchymal volume during resection of the tumor.
- Conditions
- Partial Nephrectomy, Kidney Cancer, Renal Function Aggravated
- Trial name
- NCT03323021
- Testing
- Dehydrated human amnion/chorion membrane, Standard of Care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- MiMedx Group, Inc.