Clinical trials: Delayed Gastric Emptying
Hemorrhagic Shock, Pediatric Trauma
Effect of Resuscitation on Gastric Emptying Using POCUS in Pediatric Trauma Patients
Pediatric trauma often leads to hemorrhagic shock, which reduces blood flow to the digestive tract and delays gastric emptying. This delay can cause fluid and food to remain in the stomach, increasing the risk of pulmonary…
- Conditions
- Hemorrhagic Shock, Pediatric Trauma, Delayed Gastric Emptying, Gastric Dysmotility
- Trial name
- NCT07810907
- Volunteers
- 50 people
- Sponsor
- Assiut University
Gastroparesis
Impact of KUVAN® on Gastric Relaxation in Women With Diabetic Gastroparesis.
Kuvan® (sapropterin dihydrochloride) for Improving Gastric Accommodation in Women with Diabetic Gastroparesis (KIGA-DG)
- Trial name
- NCT01135186
- Testing
- sapropterin dihydrochloride
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Stanford University
Diabetic Gastroparesis, Diabetic Gastropathy
Washed Microbiota Transplantation Alleviates Diabetic Gastrointestinal Motility Disorders: an Efficacy and Safety Study
The goal of this clinical trial is to learn about effectiveness and safety of washing microbiota transplantation in diabetic gastrointestinal motility disorders participant population.
- Conditions
- Diabetic Gastroparesis, Diabetic Gastropathy, Diabetic Gastroenteropathy, Diabetic Gastroparesis Associated With Type 2 Diabetes Mellitus
- Trial name
- NCT06340828
- Testing
- Washing Microbiota Transplantation
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Nanjing Medical University
Gastroparesis
Enterra Therapy Clinical Study (Gastric Stimulation for Gastroparesis)
This study is to evaluate the safety and effectiveness of gastric stimulation in the reduction of nausea and vomiting in patients with gastroparesis using an approved Humanitarian device.
- Trial name
- NCT00157755
- Testing
- Enterra Therapy
- Where
- 6 sites in United States
- Volunteers
- 87 people
- Sponsor
- MedtronicNeuro
Gastric Cancer Stage, Esophageal Cancer
Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy
Gastric retention not only compromises the quality of endoscopic examination but also significantly increases the risk of reflux and aspiration in sedated patients.
- Conditions
- Gastric Cancer Stage, Esophageal Cancer, Gastroparesis
- Trial name
- NCT07104214
- Where
- 3 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Zhejiang University
Functional Dyspepsia, Diabetic Gastroparesis
Assessment of Gastro-Intestinal Function to a Mixed Meal by Non-invasive Imaging
Dyspeptic symptoms, such as pain after eating, bloating and nausea all have major impact on quality of life and health care costs. When no structural cause is identified, patients are diagnosed with functional dyspepsia.
- Trial name
- NCT01919021
- Testing
- Magnetic Resonance Imaging MRI, Gamma Scintigraphy, Assessment of Gastric motor and sensory function
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Gastroparesis
G-POEM vs PEG-J in Gastroparesis Patients
Study design: A randomized non-blinded controlled clinical trial with two study arms (G-POEM and PEG-J). Treatment success is measured using the GCSI at baseline before intervention and six months after intervention with a…
- Trial name
- NCT06372132
- Testing
- G-POEM
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Maastricht University Medical Center
Gastroparesis
Buspirone for Early Satiety and Symptoms of Gastroparesis
This study evaluates whether the study medication, buspirone, an antianxiety drug, improves the symptoms of gastroparesis in patients with gastroparesis symptoms and at least moderately severe symptoms of fullness and/or…
- Trial name
- BESST (NCT03587142)
- Testing
- Buspirone
- Where
- 6 sites in United States
- Volunteers
- 96 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gastrointestinal Diseases, Stomach Diseases
A Comparison of SmartPill Capsule With Scintigraphy for Determining Gastric Residence Time
The purpose of this study is to determine the correlation between gastric residence time of the SmartPill Capsule and the time required for partial emptying of a standard radiolabeled meal as measured by gastric emptying…
- Conditions
- Gastrointestinal Diseases, Stomach Diseases, Gastroparesis
- Trial name
- NCT00128284
- Where
- 7 sites in United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- The SmartPill Corporation
Gastroparesis
Vagus Nerve Response in Gastroparesis Patients
This study aims to characterize how vagus nerve compound action potentials (CNAPs) conduct along the vagus nerve in gastroparetic patients receiving GES therapy using a flexible, non-invasive multielectrode array (MEA).
- Trial name
- NCT04207996
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Indiana University
Fasting, Gastric Stasis
Residual Gastric Volume After the Ingestion of Supplements Containing Carbohydrates and Whey Protein
Oral supplements (OS) containing carbohydrates are being used 2h before anesthesia. The addition of a nitrogen source would improve these drinks designed for the abbreviation of preoperative fasting.
- Conditions
- Fasting, Gastric Stasis, Perioperative Complication, Safety Issues
- Trial name
- NCT05573854
- Testing
- Gastric emptying after an oral supplement containing carbohydrates and whey protein, Overnight Fast
- Where
- Brazil
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
Gastroesophageal Reflux, Gastroparesis
Domperidone Expanded Access Protocol for Patients With Gastrointestinal Disorders
FDA currently allows patients 12 years of age and older with various gastrointestinal (GI) conditions to be treated with Domperidone through the Expanded Access to Investigational Drugs program.
- Conditions
- Gastroesophageal Reflux, Gastroparesis, Chronic Constipation With Overflow, Pseudo Obstruction
- Trial name
- NCT02567175
- Testing
- Domperidone
- Where
- United States
- Sponsor
- Prasanna K Kapavarapu
Organ Failure, Multiple, Indigestion
The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients
Critically ill patients are at risk of or suffering from one or more key organs or organ system failure. This study will measure the effect of traditional Chinese medicine(TCM) interventions on critically ill patients admitted to…
- Conditions
- Organ Failure, Multiple, Indigestion, Delayed Gastric Emptying, Respiratory Failure
- Trial name
- NCT06452966
- Testing
- traditional Chinese medicine, Routine ICU care, historical Routine ICU care
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- China Medical University Hospital
Gastroparesis
Gastric Per-Oral Endoscopic Myotomy (G-POEM) for the Treatment of Gastroparesis
Gastric Per-Oral Endoscopic Myotomy (G-POEM) is a procedure for the Treatment of Gastroparesis.
- Trial name
- G-POEM (NCT04434781)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Indiana University
Esophageal Cancer, Nutrition Disorders
Gastrointestinal Nutrient Transit and Enteroendocrine Function After Upper Gastrointestinal Surgery
The incidence of oesophagogastric cancer has increased by 400% since the 1970s in Ireland and the United Kingdom. In addition, refinement of perioperative management and the now widespread use of multimodal protocols for patients…
- Conditions
- Esophageal Cancer, Nutrition Disorders, Appetite Disorders, Dumping Syndrome
- Trial name
- EndoGut (NCT03734627)
- Testing
- Octreotide Acetate, Saline Solution, Paracetamol
- Where
- 2 sites in Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Gastroparesis
Diabetic Gastroparesis Study 05
This open-label study is to assess the safety of continued treatment with relamorelin for participants who previously completed the RLM-MD-03 [NCT03420781] or RLM-MD-04 [NCT03383146] study and to provide treatment for these…
- Trial name
- NCT03786380
- Testing
- Relamorelin 10 μg
- Where
- 486 sites in United States, Argentina and 28 more
- Volunteers
- 202 people
- Sponsor
- Allergan
Gastroparesis
Vagal Nerve Stimulation for Gastroparesis
This study is investigating a new form of treatment for a digestive disorder called gastroparesis. Gastroparesis is thought to be caused by a mix of inflammation and neural dysfunction.
- Trial name
- VNS (NCT03120325)
- Testing
- Vagal Nerve Stimulation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Stanford University
Gastroparesis
A Study to Evaluate the Safety and Tolerability of Virtual Reality to Treat Gastroparesis
The purpose of this study is to determine if virtual reality therapy is safe and tolerable in treating gastroparesis.
- Trial name
- NCT05079568
- Testing
- Oculus Go VR headset
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Gastroparesis
An Efficacy and Safety Study of Cisapride in Patients With Chronic Gastroparesis After Failure of Other Treatment Options
The purpose of this study is to assess the effectiveness of cisapride in patients with a primary diagnosis of chronic gastroparesis (a stomach disorder) of unknown cause.
- Trial name
- NCT01281540
- Testing
- Cisapride
- Volunteers
- 20 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Diabetic Gastroparesis
Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Exploratory Efficacy of Nimacimab in Patients With Diabetic Gastroparesis
This is a single blind phase 2a study to evaluate the safety, tolerability, pharmacokinetics, and exploratory efficacy of nimacimab in patients with diabetic gastroparesis.
- Trial name
- NCT03900325
- Testing
- Nimacimab
- Where
- 5 sites in United States
- Volunteers
- 6 people
- Sponsor
- Bird Rock Bio, Inc.