Clinical trials: Delayed Gastric Emptying
Chronic Nausea, Chronic Nausea and Vomiting Syndrome
Evaluating Whether a Nausea Band Reduces Symptoms in Those With Chronic Nausea Vomiting
The goal of this clinical trial is to learn whether a wearable transcutaneous electrical nerve stimulation (TENS) device called EmeTerm can help reduce nausea in adults who have had nausea for 2 months or longer and who receive…
- Trial name
- WINNER (NCT07720323)
- Testing
- EmeTerm wearable TENS device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Ohio State University
Gastroparesis
Vagal Nerve Stimulation for Gastroparesis
This study is investigating a new form of treatment for a digestive disorder called gastroparesis. Gastroparesis is thought to be caused by a mix of inflammation and neural dysfunction.
- Trial name
- VNS (NCT03120325)
- Testing
- Vagal Nerve Stimulation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Stanford University
Gastroparesis
Indiana University Gastric Electrical Stimulation Registry
The purpose of this study is to develop a clinical registry in patients with Gastric Electrical Stimulation (GES) therapy for gastroparesis to support future gastrointestinal therapies, medical procedures and diagnostics.
- Trial name
- NCT05047289
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Indiana University
Gastroparesis
An Efficacy and Safety Study of Cisapride in Patients With Chronic Gastroparesis After Failure of Other Treatment Options
The purpose of this study is to assess the effectiveness of cisapride in patients with a primary diagnosis of chronic gastroparesis (a stomach disorder) of unknown cause.
- Trial name
- NCT01281540
- Testing
- Cisapride
- Volunteers
- 20 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Gastroparesis, Gastrointestinal Disorder, Functional
Protease Activated Receptor-2 and Gastrointestinal Dysfunction in Critical Illness
Gastrointestinal (GI) dysfunction affects up to 50% of medical and surgical critically ill children. GI dysfunction, specifically gastric dysmotility and loss of epithelial barrier integrity, is associated with significant…
- Conditions
- Gastroparesis, Gastrointestinal Disorder, Functional, Critical Illness
- Trial name
- NCT03011151
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Boston Children's Hospital
Gastroparesis Due to Diabetes Mellitus Type I
Pathophysiology of Diabetic Gastroparesis
The goal of this study is to explore the pathophysiology of diabetic gastroparesis by conducting an exploratory cohort study. Participants will be type 1 diabetes patients with and without gastroparesis.
- Trial name
- PATODIAG (NCT05717205)
- Testing
- technetium scitigraphy
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Hvidovre University Hospital
Diabetic Gastroparesis
Thoracic Splanchnic Magnetic Neuromodulation Therapy (ThorS-MagNT) for Grade 3 Diabetic Gastroparesis: Pilot Study
Diabetic gastroparesis (DG) is an under recognized and significant complication of diabetes with lack of effective treatments. Recently, a 4-fold increase in hospitalizations has been seen in DG patients with refractory symptoms…
- Trial name
- ThorS-MagNT (NCT04706832)
- Testing
- Thoracic Splanchnic Magnetic Neuromodulation Therapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Augusta University
Diabetic Gastroparesis, Diabetic Gastropathy
Washed Microbiota Transplantation Alleviates Diabetic Gastrointestinal Motility Disorders: an Efficacy and Safety Study
The goal of this clinical trial is to learn about effectiveness and safety of washing microbiota transplantation in diabetic gastrointestinal motility disorders participant population.
- Conditions
- Diabetic Gastroparesis, Diabetic Gastropathy, Diabetic Gastroenteropathy, Diabetic Gastroparesis Associated With Type 2 Diabetes Mellitus
- Trial name
- NCT06340828
- Testing
- Washing Microbiota Transplantation
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Nanjing Medical University
Gastroparesis
GEBT Lot-to-Lot and Biological Variability
The purpose of this study is to collect information regarding lot-to-lot variability in 13C-Spirulina test meal lets and within-subject biological variability.
- Trial name
- NCT04772261
- Testing
- 13C-Spirulina GEBT
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
Gastroparesis
Safety and Pharmacokinetic Study of C13-URA in Healthy Volunteers
The purpose of this study is to evaluate the safety and establish the pharmacokinetic (PK) profile of C13-URA in healthy volunteers
- Trial name
- NCT01074710
- Testing
- [2-13C] uracil
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Diabetic Gastroparesis, Idiopathic Gastroparesis
A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants With Symptomatic Diabetic or Idiopathic Gastroparesis
The purpose of this study is to assess the safety and efficacy of various dose levels of NG101 compared with placebo in adult participants with gastroparesis during 12 weeks of treatment.
- Trial name
- NCT04303195
- Testing
- NG101
- Where
- 83 sites in United States
- Volunteers
- 161 people
- Sponsor
- Neurogastrx, Inc.
Type 1 Diabetes, Gastroparesis Due to Diabetes Mellitus Type I
To Study the Efficacy and Safety of Medtronic 780G Insulin Pump in People With Gastroparesis and Type 1 Diabetes.
The goal of this clinical trial is to evaluate the efficacy and safety of Medtronic 780G automated insulin delivery system in adult persons with type 1 diabetes and gastroparesis.
- Trial name
- NCT07287943
- Testing
- Medtronic 780G AID
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Viral N. Shah
Gastrointestinal Motility Disorder, Gastroparesis
IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy
Patients with the symptoms of generalized GI dysmotility, including gastroparesis, are sometimes refractory to available medications, devices and other interventions/ Some of these patients have serologic and/or endo organ…
- Conditions
- Gastrointestinal Motility Disorder, Gastroparesis, Neuropathy
- Trial name
- GAIN (NCT04208828)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Louisville
Gastroparesis, Gastroparesis-like Syndrome
GpCRC Pediatric Gastroparesis Registry 2
The objective of the Pediatric Gastroparesis Registry 2 is to create a national prospective registry of children, adolescents, and young adults with gastroparesis and gastroparesis-like syndrome (symptoms of gastroparesis but…
- Trial name
- PGpR2 (NCT05981300)
- Where
- 6 sites in United States
- Volunteers
- 216 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Obesity, Over Weight
Endoscopic Suturing of the Gastric Pylorus to Delay Gastric Emptying and Treat Obesity
The purpose of this study is to demonstrate the efficacy and safety of endoscopic suturing of the gastric pylorus to delay gastric emptying and treat obesity.
- Trial name
- NCT02191501
- Testing
- Pyloric restriction
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Northwell Health
Diabetic Gastroparesis, Idiopathic Gastroparesis
G-POEM for Treatment of Refractory Gastroparesis
This study is performed to assess the efficacy and outcomes of Gastric Per Oral Endoscopic Myotomy "G-POEM" in patients presenting with gastroparesis.
- Conditions
- Diabetic Gastroparesis, Idiopathic Gastroparesis, Gastroparesis Postoperative
- Trial name
- NCT02732821
- Testing
- Gastric Per Oral Endoscopic Myotomy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
Gastric Cancer
The Advantages and Disadvantages Between Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction After Laparoscopy-assisted Distal Gastrectomy for Gastric
The Advantages and Disadvantages Between Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction After Laparoscopy-assisted Distal Gastrectomy for Gastric.
- Trial name
- NCT02694081
- Testing
- Uncut Roux-en-Y Reconstruction, Billroth II Reconstruction
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jilin University
Esophageal Achalasia, Gastroparesis
Respiratory and Hemodynamic Implications of Endoscopic Myotomy of the Esophagus and Stomach
The goal of this observational study is to learn about hemodynamic and respiratory repercussions during general anesthesia in patients with achalasia or gastroparesis who underwent an endoscopic treatment such as a peroral…
- Trial name
- NCT05602272
- Testing
- General anesthesia for per-oral endoscopic myotomy
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Irritable Bowel Syndrome (IBS), Functional Dyspepsia
Interactive Effects of Early-Life Stress, Diet, and Metabolism on Gastrointestinal Dysfunction With Neuropsychiatric Symptoms
The goal of this observational case-control study is to learn how stressful experiences, dietary habits, and blood nutrient levels are associated with gastrointestinal symptoms and symptoms of depression and anxiety in adults…
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Dyspepsia, Inflammatory Bowel Disease (IBD), Gastroparesis
- Trial name
- NCT07852819
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shandong University
Pancreaticoduodenectomy, Delayed Gastric Emptying
Comparison Between Pylorus-resecting and Preserving Pancreaticoduodenectomy on Delayed Gastric Emptying and Nutrition
Pylorus preserving pancreaticoduodenectomy has been standard procedure for periampullary benign and malignant disease. Delayed gastric emptying is one of most common complications after the procedure.
- Conditions
- Pancreaticoduodenectomy, Delayed Gastric Emptying, Nutrition
- Trial name
- NCT05314244
- Testing
- Pylorus resecting pancreaticoduodenectomy
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center