Clinical trials: Delayed Gastric Emptying, active
GERD, Gastroesophageal Reflux
Compassionate Use of Domperidone for Refractory Gastroparesis
The purpose of this program is to allow the use of domperidone in children from 12 to 21 years of age with symptoms related to motility disorders and Gastroesophageal reflux disease (GERD) who have failed all the standard…
- Conditions
- GERD, Gastroesophageal Reflux, Gastroparesis
- Trial name
- NCT04699591
- Testing
- Domperidone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Jose Cocjin
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Gastroparesis
G-POEM vs PEG-J in Gastroparesis Patients
Study design: A randomized non-blinded controlled clinical trial with two study arms (G-POEM and PEG-J). Treatment success is measured using the GCSI at baseline before intervention and six months after intervention with a…
- Trial name
- NCT06372132
- Testing
- G-POEM
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Maastricht University Medical Center
Gastroparesis
The Use of Body Surface Gastric Mapping in Assessing the Clinical Success of G-POEM
The purpose of this study is to investigate whether or not the investigators can utilize Body Surface Gastric Mapping to determine who would best benefit to receive G-POEM procedure and how Body Surface Gastric Mapping can be…
- Trial name
- NCT06493032
- Testing
- Gastric Alimetry System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Vomiting, Feeding Disorders
Use of Intrapyloric Botulinum Injections in Children
This study aims to evaluate the effect of intrapyloric botulinum toxin in children with feeding disorders.
- Conditions
- Vomiting, Feeding Disorders, Gastroparesis
- Trial name
- NCT04250844
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Fasting, Delayed Gastric Emptying
Gastric Assessment of Pediatric Patients Undergoing Surgery
The goal of this pilot prospective cohort study is to examine the reproducibility of gastric volume and emptying as measured by gastric ultrasound and its correlation to a gold-standard test for gastric emptying in the…
- Conditions
- Fasting, Delayed Gastric Emptying, Aspiration Pneumonia, Respiratory Aspiration of Gastric Content
- Trial name
- NCT05674643
- Testing
- Gastric Ultrasound Baseline Scans, Acetaminophen Absorption Test (AAT), Gastric Ultrasound Serial Scans
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Diabetic Gastroparesis
Washed Microbiota Transplantation for Diabetic Gastroparesis
This is a randomized controlled trial to explore the efficacy and safety of washed microbiota transplantation (WMT) for diabetic gastroparesis (DGP) patients.
- Trial name
- NCT06340217
- Testing
- washed microbiota transplantation
- Where
- China
- Volunteers
- 46 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Gastroparesis
Combined Role of Gastric Peroral Endoscopic Myotomy and Gastric Electrical Stimulator
This study is looking at how safe and effective G-POEM, GES and a combination of both are for people with severe stomach problems (gastroparesis) that haven't gotten better with medicine.
- Trial name
- NCT07526935
- Testing
- GES + Upper endoscopy, GES on + Upper endscopy, GES off + G-POEM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor Research Institute
Gastroparesis, Functional Dyspepsia
Prokinetics and Body Surface Gastric Mapping in Dyspeptic Patients: Baseline and Treatment Effects
Functional dyspepsia and gastroparesis are common stomach disorders with symptoms like early satiety, nausea, and abdominal pain, and are often evaluated with gastric emptying tests, although the correlation with symptoms is…
- Trial name
- NCT06854120
- Testing
- Gastric Alimetry
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 125 people
- Sponsor
- University of Auckland, New Zealand
Parenteral Nutrition, Gastroparesis
Achieving nuTritional Target in criticAlly Ill patieNts With iMpairEd gastroiNtesTinal Dysfunction
Clear study hypothesis / research question It has already been proven that a prolonged negative energy balance during intensive care stay is an independent risk factor for mortality.
- Conditions
- Parenteral Nutrition, Gastroparesis, Gastrointestinal Dysfunction, Protein Deficiency
- Trial name
- ATTAINMENT (NCT06510348)
- Testing
- Supplemental Parenteral Nutrition (SPN)
- Where
- Romania
- Volunteers
- 164 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition
Gastroparesis Postoperative, Delayed Gastric Emptying Following Procedure
Acupuncture for Postoperative Gastric Emptying Delay
This multicenter clinical trial, conducted at Qilu Hospital of Shandong University and collaborating institutions, prospectively assesses the efficacy and safety of acupuncture for postoperative delayed gastric emptying.
- Trial name
- APOGEE (NCT07505927)
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Qilu Hospital of Shandong University
Gastroparesis
Gastric Per-Oral Endoscopic Myotomy (G-POEM) for the Treatment of Gastroparesis
Gastric Per-Oral Endoscopic Myotomy (G-POEM) is a procedure for the Treatment of Gastroparesis.
- Trial name
- G-POEM (NCT04434781)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Indiana University
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Gastric Pathophysiology in Diabetes
This is a comprehensive pathophysiological study assessing various gastric functions in patients with diabetes mellitus. The investigators aim to examine the stomach with various measurement devices to gain information about its…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Functional Dyspepsia, Gastroparesis
- Trial name
- DiaFLIP (NCT06068114)
- Where
- 5 sites in Czechia, Slovakia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical and Experimental Medicine
Diabetes Mellitus, Gastroparesis With Diabetes Mellitus
Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes
This study will assess changes in glycemic control in 40 patients with diabetes who undergo per-oral pyloromyotomy (POP) for medically refractory gastroparesis.
- Conditions
- Diabetes Mellitus, Gastroparesis With Diabetes Mellitus, Gastroparesis
- Trial name
- NCT04696159
- Testing
- Pyloromyotomy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Matthew Allemang
Pulmonary Aspiration During Anaesthetic Induction
Effects of Beginning a GLP1-Agonist Therapy on Residual Gastric Content and Gastric Emptying
This project explores the elevated risk of pulmonary aspiration during anesthesia in patients undergoing GLP-1 agonist therapy, which prolongs gastric emptying.
- Trial name
- GLP-1 (NCT06659159)
- Testing
- Gastric ultrasound
- Volunteers
- 50 people
- Sponsor
- Sascha Battig
Gastroparesis, Chronic Abdominal Pain
Gastric Electrical Stimulation for Abdominal Pain in Patients With Gastroparesis
Gastroparesis is a disorder characterized by delayed gastric emptying and symptoms including nausea, vomiting, and abdominal pain.
- Trial name
- HEAL (NCT07556237)
- Testing
- Enterra™ neurostimulator
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Louisville
Gastrointestinal Motility Disorders in Children, Functional Gastrointestinal Disorders
BSGM to Evaluate Patients With GI Symptoms
The goal of this observational study is to learn about gastric myoelectric activity in children with GI symptoms. The main question it aims to answer is which patterns or signals are associated with GI symptoms as measured by a…
- Conditions
- Gastrointestinal Motility Disorders in Children, Functional Gastrointestinal Disorders, Gastroparesis, Dyspepsia and Other Specified Disorders of Function of Stomach
- Trial name
- NCT05880199
- Testing
- Body surface gastric mapping device
- Where
- 5 sites in United States
- Volunteers
- 685 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Digestive System Disorder, Dyspepsia
Domperidone in Treating Patients With Gastrointestinal Disorders
This phase III trial studies how well domperidone works in treating patients with gastrointestinal disorders. Domperidone may help control chronic gastrointestinal disorders and their symptoms, such as pain, bloating, and nausea…
- Conditions
- Digestive System Disorder, Dyspepsia, Esophagitis, Gastroesophageal Reflux Disease
- Trial name
- NCT01696734
- Testing
- Domperidone, Questionnaire Administration
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- M.D. Anderson Cancer Center
Achalasia, Esophageal Spasm, Diffuse
Prospective Evaluation of the Clinical Utility of Peroral Endoscopic Myotomy for Gastrointestinal Motility Disorders
This is prospective data recording study. All patients will receive standard medical care and no experimental interventions will be performed.
- Conditions
- Achalasia, Esophageal Spasm, Diffuse, Gastroparesis, Swallowing Disorder
- Trial name
- POEM (NCT05905016)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- AdventHealth
Gastric Emptying, Delayed Gastric Emptying
Prevalence and Measurement of Delayed Gastric Emptying in Patients Receiving Extracorporeal Membrane Oxygenation
The goal of this observational study is to learn whether the stomach takes longer to empty in patients on the intensive care unit who are receiving ECMO (a machine that temporarily takes over the role of the lungs and heart)…
- Conditions
- Gastric Emptying, Delayed Gastric Emptying, Critical Illness, ExtraCorporeal Membrane Oxygenation (ECMO)
- Trial name
- PROPEL-ECMO (NCT07779174)
- Testing
- Gastric (stomach) ultrasound measurement, 'Residual volume' measurement, Scintigraphy (standard research method)
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust