Clinical trials: Delayed Neurocognitive Recovery
Older Adults, Surgery
Perioperative Transcranial Photobiomodulation and Delayed Neurocognitive Recovery in Older Patients
Delayed neurocognitive recovery is a common neurocognitive complication in older patients after surgery, especially those with preoperative neurocognitive decline.
- Conditions
- Older Adults, Surgery, Transcranial Photobiomodulation, Delayed Neurocognitive Recovery
- Trial name
- NCT07736092
- Testing
- Transcranial photobiomodulation therapy, Transcranial pseudo-photobiomodulation
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Delayed Neurocognitive Recovery
Olfactory Function and Delayed Neurocognitive Recovery
To explore whether odor enrichment can reduce the risk of delayed neurocognitive recovery as an intervention strategy.
- Trial name
- NCT03441074
- Testing
- Odor Enrichment
- Where
- China
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Delayed Emergence From Anesthesia, Postoperative Delirium
Trajectory of Recovery in the Elderly
The purpose of this study is to understand how elderly individuals regain their cognitive skills following general anesthesia. The investigators will compare an age stratified group of volunteers who will be evaluated with a…
- Conditions
- Delayed Emergence From Anesthesia, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- TORIE (NCT02275026)
- Testing
- Functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Elderly Patients, Cancer Surgery
Targeted Temperature Management on Delayed Neurocognitive Recovery in Older Patients After Major Cancer Surgery
With aging population, more older patients will receive major surgery for cancer. Older patients are at increased risk of postoperative neurocognitive complications including delayed neurocognitive recovery (dNCR), which is…
- Conditions
- Elderly Patients, Cancer Surgery, Hypothermia, Accidental, Targeted Temperature Management
- Trial name
- NCT07655687
- Testing
- Target temperature management, Routine thermal management
- Where
- 2 sites in China
- Volunteers
- 1,512 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Elderly, Noncardiac Surgery
Impact of Esketamine on Delayed Neurocognitive Recovery in Older Patients
Esketamine is frequently used during the perioperative period for supplemental analgesia. Small sample size trials showed that subanesthetic dose esketamine may decrease postoperative neurocognitive complications.
- Conditions
- Elderly, Noncardiac Surgery, Delayed Neurocognitive Recovery, Postoperative Delirium
- Trial name
- NCT07523334
- Testing
- Esketamine 1, Esketamine 2, Esketamine 3
- Where
- 2 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Delayed Neurocognitive Recovery
Study on the Characteristics of Non-targeted Metabolomics and EEG of Delayed Neurocognitive Recovery in Elderly Patients
Perioperative neurocognitive disorder (PND) refers to a broad range of postoperative cognitive complications, including preoperatively diagnosed cognitive decline, postoperative delirium (POD), delayed neurocognitive recovery…
- Trial name
- NCT05105451
- Testing
- Collecting clinical data, EGG，arterial blood gas data and venous blood sample
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Cognitive Dysfunction, Emergence Delirium
Effects of Hypothermia on Delayed Neurocognitive Recovery (DNR): an Observational Trial Among Patients Undergoing Cardiac-Surgery
Post-operative cognitive dysfunction is a common disease in patient undergoing general anaesthesia, especially in older patients.
- Conditions
- Cognitive Dysfunction, Emergence Delirium, Hypothermia
- Trial name
- DNR (NCT03636074)
- Testing
- Hypothermia during Extracorporeal Circulation
- Where
- Italy
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Padova