Clinical trials: Delayed Onset Muscle Soreness
Exercise Induced Muscle Damage, Physical Activity
Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS).
- Conditions
- Exercise Induced Muscle Damage, Physical Activity, Inflammation, Exercise Recovery
- Trial name
- WIO (NCT06810271)
- Testing
- Eccentric resistance exercise
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes, Healthy Individuals
The Effects of Orally Ingesting Branched Chained Amino Acids on Delayed Onset Muscle Soreness in Diabetic Patients
The purpose of this study is to determine the effectiveness of the 3 Branched Chained Amino Acids (isoleucine, leucine, and valine) on treating Delayed Onset Muscle Soreness, a type of muscle pain which usually develops after…
- Trial name
- NCT01211717
- Testing
- Branched Chained Amino Acids
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Delayed Onset Muscle Soreness
Effects of a Polyherbal Supplement on the Signs and Symptoms of Delayed Onset Muscle Soreness
This study is a randomized, double-blind, placebo-controlled, crossover design study in healthy subjects to determine the effects of a polyherbal supplement on the signs and symptoms of delayed onset muscle soreness (DOMS)…
- Trial name
- NCT02157675
- Testing
- Polyherbal capsule
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- NewChapter, Inc.
Muscle Soreness
Topical CBD's Effects on Soreness and Performance
Exercise-induced muscle damage (EIMD) results from unaccustomed exercise and can lead to delayed onset muscle soreness (DOMS). Impairments associated with EIMD and DOMS can result in moderate-to-severe discomfort and hindered…
- Trial name
- NCT06320327
- Testing
- Cannabidiol cream
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Joseph Pastina
Delayed Onset Muscle Soreness (DOMS)
The Effect of Percussion Massage Therapy on the Recovery of DOMS in Physically Active Young Men Delayed Onset Muscle Soreness = DOMS
The goal of this clinical trial is to learn the effect of percussion massage therapy (PMT) on the recovery of delayed onset muscle soreness (DOMS) in physically active young men.
- Trial name
- Required (NCT06612502)
- Testing
- Static stretching, Fascia gun ( Short-time PMT ), Fascia gun ( Long-time PMT )
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanxi Normal University
Recovery Methods, Exercise and Recovery
Effects of Carnitine Supplementation on Exercise-Induced Muscle Damage: A Randomized Controlled Trial
This clinical study aims to investigate the effects of L-carnitine supplementation on recovery following high-intensity interval exercise in young athletes.
- Conditions
- Recovery Methods, Exercise and Recovery, Exercise Fatigue, Carnitine Ingestion
- Trial name
- NCT07492446
- Testing
- L-Carnitine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Delayed Onset Muscle Soreness (DOMS), Exercise-Induced Muscle Soreness
A Study of Mitragynine Formulations for Exercise-Induced Muscle Soreness in Healthy Adults
This Phase II randomized, double-blind, placebo-controlled study will evaluate the safety, tolerability, and physical dependence potential of mitragynine-containing formulations after 28 days of use and assess their effects on…
- Trial name
- NCT07809282
- Testing
- SpecioTea, MitraPlex
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Traditional Naturals Research Inc.
Pain, Acute
Controlled Study to Assess the Efficacy and Safety of S-Ibuprofen Topical Gel 5% (AP0302) in the Treatment of DOMS
Phase 2 study designed to evaluated analgesic efficacy and safety of S-Ibuprofen Topical Gel 5%
- Trial name
- NCT03852459
- Testing
- S-Ibuprofen, Vehicle
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Aponia Laboratories, Inc.
Healthy
The Effect of Thermotherapy on Recovery and Performance
This study investigates the effects of cooling on the recovery and performance characteristic in young healthy subjects. The study is divided in two projects: Project A: investigates the effects of 20 min.
- Trial name
- Cryotherapy (NCT02506283)
- Testing
- Zamar Therapy CT clinic
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Muscle Soreness, Delayed-onset Muscle Soreness
Effects of ReWin(d) Supplementation on the Recovery of DOMS Induced by Acute Exercice
The study will assess the recovery and performance of young athletes suffering from muscle damage induced by physical exercise. Model by comparing the safety and efficacy of ReWin(d) supplemention during 4 weeks to placebo over…
- Trial name
- NCT03961022
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Natural Origins
Muscle Soreness
Ibuprofen Versus Placebo For Muscle Soreness
The study will assess the sensitivity of the Delayed Onset Muscle Soreness Model by comparing the safety and efficacy of oral ibuprofen to placebo over 24 hours.
- Trial name
- NCT03228992
- Testing
- Ibuprofen 400 mg
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Jean Brown Research
Phototherapy
Effects of Light Emitting Diodes (LED) Therapy in Rugby Athletes
Therapy with light emitting diodes (LED) is a good resource to accelerate the recovery of the athlete and reduce muscle damage caused by exercise.
- Trial name
- NCT03728439
- Testing
- LED before, LED interval, LED after
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Photobiomodulation on NMES-Induced Muscle Fatigue and Damage
Neuromuscular electrical stimulation (NMES) is effective for strength training and rehabilitation, but non-selective motor unit recruitment often induces rapid fatigue, discomfort, and muscle damage.
- Conditions
- Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS), Muscle Damage, Photobiomodulation (PBM)
- Trial name
- NCT07790016
- Testing
- Photobiomodulation Therapy (PBMT)
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Acute Pain
A Study to Evaluate the Efficacy and Safety of K-285 Compared With Menthol Gel for the Treatment of Delayed Onset Muscle Soreness (DOMS) in the Lower Extremity
The purpose of this study to evaluate the efficacy and safety of K-285 compared with menthol gel for the treatment of delayed onset muscle soreness (DOMS) in the lower extremity.
- Trial name
- NCT04484428
- Testing
- K-285, Menthol
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Kowa Research Institute, Inc.
Pain Intensity
Effect of Blood Flow Restriction Technique on Delayed Onset Muscle Soreness
The aim of our study is to determine and evaluate the effects of blood flow restriction technique on pain, biomechanical properties and strength of the muscle in delayed onset muscle pain in healthy individuals.
- Trial name
- NCT06389747
- Testing
- BFR technique
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Delayed Onset Muscle Soreness
An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Efficacy and Safety of Voltaren Gel in Subjects With DOMS
The purpose of this study is to evaluate analgesic efficacy of Topical Voltaren Gel (diclofenac sodium gel) 1% applied QID compared to Placebo in Subjects Experiencing Delayed Onset Muscle Soreness.
- Trial name
- NCT02087748
- Testing
- 1% diclofenac sodium gel
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lotus Clinical Research, LLC
Myalgia
Diosmin for Treatment of Delayed-onset Muscle Soreness (DOMS)
The potential benefits of exercise for the treatment of chronic inflammatory diseases and pain have been well documented in the scientific literature.
- Trial name
- UEL (NCT06125002)
- Testing
- Diosmin750
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sergio Marques Borghi
Delayed Onset Muscle Soreness (DOMS), Healthy
Posterior Chain Responses to Gastrocnemius DOMS
The goal of this clinical trial is to learn how delayed onset muscle soreness (DOMS) in the calf muscle (gastrocnemius) affects the muscles of the posterior chain and physical performance in healthy young adults.
- Trial name
- NCT07324395
- Testing
- Gastrocnemius DOMS Induction Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ebru Aloğlu Çiftçi
Delayed Onset Muscle Soreness
Effects of Foam Roller Versus KT Tape on Delayed Onset Muscle Soreness
Objective of this study is to compare the effects of foam roller with KT tape on DOMS. The university going students will be divided in two groups, with one group receiving Kinesio Tape as intervention and other Foam Rolling as…
- Trial name
- NCT06076356
- Testing
- Foam Rolling, Kinesio Taping
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Delayed Onset Muscle Soreness
Dosing Interval Study of SST-0225 Topical Ibuprofen Cream in the Treatment of Delayed Onset Muscle Soreness
This is a Phase 2, prospective, randomized, dual-center, double-blind, placebo-controlled, parallel-group study designed to determine the dosing interval, efficacy and safety of SST-0225 (5.4 grams, applied up to 6 times in 24…
- Trial name
- DIS DOMS (NCT02339129)
- Testing
- SST-0225
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Strategic Science & Technologies, LLC