Clinical trials: Delirium, Intensive Care Unit, Randomised Controlled Trial
Delirium
Dexmedetomidine to Lessen Intensive Care Unit (ICU) Agitation
The primary aim of the DahLIA trial is to determine, in patients with ICU-associated delirium and agitation who are otherwise pathophysiologically stable (as defined), the number of ventilator-free hours in the incident ICU…
- Trial name
- DahLIA (NCT01151865)
- Testing
- Dexmedetomidine
- Where
- 7 sites in Australia
- Volunteers
- 96 people
- Sponsor
- Austin Health
Delirium, Critical Illness
Haloperidol for Delirium in Adult Critically Ill Patients
The EuRIDICE trial will study whether haloperidol as a first line treatment for ICU delirium reduces delirium duration (and severity).
- Conditions
- Delirium, Critical Illness, Intensive Care Psychosis, Cognitive Impairment
- Trial name
- EuRIDICE (NCT03628391)
- Testing
- Haloperidol
- Where
- 8 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- Erasmus Medical Center
Adult Disease, Intensive Care Unit Syndrome
Low-dose Dexmedetomidine in Mechanically Ventilated ICU Patients
For patients undergoing mechanical ventilation, light sedation is better than deep sedation for the outcomes, which is manifested as shortened length of ICU stay, shortened duration of mechanical ventilation, and decreased…
- Conditions
- Adult Disease, Intensive Care Unit Syndrome, Mechanical Ventilation Complication, Delirium
- Trial name
- NCT03172897
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Peking University First Hospital
Myocardial Infarction (MI), Delirium, Intensive Care Unit, Randomised Controlled Trial
Mannitol Administration for Delerium Prevention
The aim of the study is to evaluate the efficacy of adjuvant administration of mannitol for the prevention of delirium in patients with myocardial infarction.
- Trial name
- MAD (NCT06759259)
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Sleep, Delirium
Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion Bundle
Patients frequently experience problems with sleep while admitted to the ICU. Good sleep is important in ensuring that your immune system responds properly to infection, for your heart to function optimally, and to support normal…
- Conditions
- Sleep, Delirium, ICU Hospitalization, Critical Illness
- Trial name
- DELDEX (NCT06824077)
- Testing
- Dexmedetomidine
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Delirium, Intensive Care Unit, Randomised Controlled Trial
The Effects of a Model-based Sensory Stimulation Intervention on Preventing Delirium Among Intensive Care Unit Patients: A Randomised Controlled Trial
Delirium is highly associated with adverse clinical outcomes of intensive care unit (ICU) patients, including increased cognitive impairment, duration of intubation, ICU length of stay, mortality, physical dependence, and health…
- Trial name
- NCT04306016
- Testing
- Sensory stimulation
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Chinese University of Hong Kong
Delirium, Intensive Care Unit
Effectiveness of a Virtual Reality-Based Sensory Stimulation Intervention in Preventing Delirium in Intensive Care Units
The goal of this clinical trial is to evaluate the effectiveness of a VR-based sensory stimulation system in preventing ICU delirium in patients.
- Conditions
- Delirium, Intensive Care Unit, Randomised Controlled Trial
- Trial name
- NCT06153472
- Testing
- VR-based intervention
- Volunteers
- 324 people
- Sponsor
- Chinese University of Hong Kong
Delirium
Melatonin for Treatment of Delirium in Critically Ill Adult Patients
The purpose of this study is to determine the feasibility of conducting a randomized controlled trial (RCT) with melatonin for treatment of delirium in critically ill adult patients.
- Trial name
- DELIRE-ICU (NCT05713877)
- Testing
- Melatonin
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Delirium, Intensive Care Unit Syndrome
Education for Recognition and Management of Delirium
Delirium is a disturbance in consciousness with reduced ability to focus, sustain, or shift attention that occurs over a short period of time and tends to fluctuate over the course of the day.
- Conditions
- Delirium, Intensive Care Unit Syndrome, Nurse-Patient Relations
- Trial name
- NCT03642249
- Testing
- OSCEs, Lecture, E-learning
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University