Clinical trials: Delirium, completed
Delirium, Cognitive Dysfunction
Post-operative Delirium (POD) in Patients Undergoing Hip Fracture Surgery
The primary endpoint of the study is the appearance of Post Operative Delirium within the first 3 months. The secondary endpoints are the development of POCD, dementia of any type of new onset at 12 months, mortality at 30 days…
- Trial name
- NCT05105906
- Testing
- cognitive tests performed
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Post Operative Delirium, Post Operative Pain
Peritonsillar Bupivacaine Infiltration After Tonsillectomy In Children
To evaluate the effect of peritonsillar bupivacaine infiltration on the development of postoperative delirium in pediatric patients undergoing tonsillectomy or adenotonsillectomy.
- Trial name
- NCT06863714
- Testing
- peritonsillar bupivacaine injection
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Postoperative Delirium, Elderly Patient
Diagnosis, Incidence and Consequences of PACU-Delirium
This study aims to 1. determine sensitivity and specificity of the Confusion Assessment Method for Postanesthesia Care Unit (CAM-PACU) 2.
- Conditions
- Postoperative Delirium, Elderly Patient, Cognitive Decline
- Trial name
- PADE-DIC (NCT04978870)
- Where
- Germany
- Volunteers
- 450 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postoperative Delirium
Postoperative Cognitive Training to Prevent Delirium
The aim of this clinical trial is to test whether daily postoperative cognitive training can prevent delirium in older patients after major surgery.
- Trial name
- DELtrain (NCT06601673)
- Testing
- Cognitive training, Listen to audio book
- Volunteers
- 108 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Regional Anaesthesia, Postoperative Delirium (POD)
Association of Transversus Abdominis Plane Block (TAPB) with Postoperative Delirium (POD) in Elderly Patients Undergoing Major Gastrointestinal Surgery
Postoperative delirium can increase postoperative adverse reactions and prognosis in elderly patients undergoing gastrointestinal surgery.
- Conditions
- Regional Anaesthesia, Postoperative Delirium (POD), Transversus Abdominis Plane Block (TAP Block)
- Trial name
- NCT06829108
- Volunteers
- 5,220 people
- Sponsor
- Chinese PLA General Hospital
Emergence Delirium
Emergence Agitation of Sevoflurane in Pediatric
Low dose nalbuphine versus dexmedetomidine on prevention of emergence agitation in children
- Trial name
- NCT06830564
- Testing
- we will give the patient 0.1 mg nalbuphine 15 min before the end of the procedure, we will give the patient 0.5 mg dexmedetomidine 15 min before the end of the procedure
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Delirium, Pain
Evaluation of Quality Indicators on Analgesia, Sedation and Delirium in Intensive Care Patients and Their Impact on Outcome Indicators and Economic Indicators
Retrospective cohort study to investigate the adherence to the process indicators for pain management, sedation management and management of delirium on outcome indicators and cost/revenues in individual patients and subcohorts.
- Trial name
- NCT05384613
- Where
- Germany
- Volunteers
- 20,220 people
- Sponsor
- Charite University, Berlin, Germany
Postoperative Delirium
Postoperative Delirium - European Society of Anaesthesiology Survey
The ESA is currently preparing a guideline on the management of postoperative delirium (POD), which attempts to reduce the impact of postoperative delirium and provide recommendations for prevention, diagnostics and treatment of…
- Trial name
- NCT02513537
- Where
- 4 sites in Germany, Italy and 2 more
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Delirium, Intensive Care Unit Delirium
Partnering With Family Members to Prevent, Detect and Manage Delirium in Critically Ill Patients.
Almost half of critically ill patients experience delirium. Delirium is associated with impaired cognition, mortality, and increased healthcare costs.
- Conditions
- Delirium, Intensive Care Unit Delirium, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- NCT04099472
- Testing
- Delirium Education, Prevention, and Management, Standard Care
- Where
- 4 sites in Canada
- Volunteers
- 128 people
- Sponsor
- University of Calgary
Delirium, Post-operative Delirium
Nitric Oxide Levels Were Associated With Postoperative Delirium Following Cardiac Surgery
This study is a single-center prospective observational study conducted at the operating room, post-anesthesia care unit, and ICU of Tongji Hospital, from April 2023 to September 2024.
- Trial name
- NCT06748391
- Where
- China
- Volunteers
- 1,939 people
- Sponsor
- Tongji Hospital
Postoperative Delirium
Postoperative Delirium: EEG Markers of Sleep and Wakefulness
Postoperative delirium is a condition in which patients develop temporary difficulties in maintaining attention and thinking clearly. These new problems can appear after surgery and change throughout the day.
- Trial name
- NCT03291626
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Washington University School of Medicine
Pregabalin, Dexmedetomidine
Pregabalin Versus Dexmedetomidine for Delirium Prevention After Cardiac Surgery
The aim of this study is to compare the effect of perioperative administration of pregabalin versus dexmedetomidine on the prevalence and lasting duration of delirium in elderly patients after cardiac surgery.
- Conditions
- Pregabalin, Dexmedetomidine, Delirium
- Trial name
- NCT05640479
- Testing
- Pregabalin, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Cerebral Oxygen Desaturation, Post-operative Delirium
Cerebral Oxygenation in Total Hip Arthroplasty Patients
We plan to investigate the relationship between hypotensive epidural anesthesia for hip arthroplasty and cerebral oxygen saturation.
- Trial name
- THANIRS (NCT02325154)
- Testing
- Cerebral Oximeter
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Postoperative Delirium (POD)
Validation of a Risk Assessment Model for Postoperative Delirium Based on Artificial Intelligence
Postoperative delirium (POD) is a frequent postoperative complication in the elderly, characterised by fluctuating disturbances in attention, awareness, and cognition.
- Trial name
- NCT05639348
- Testing
- Data collection on POD for calculation of the PIPRA score
- Where
- 3 sites in Switzerland
- Volunteers
- 993 people
- Sponsor
- University Hospital, Basel, Switzerland
Degenerative Disc Disease
TXA in Spinal Fusion
Tranexamic acid and placebo will be given during surgery to patients who have elected to undergo lumber interbody fusion on 2 or more levels.
- Trial name
- NCT04272606
- Testing
- Tranexamic Acid, Saline Solution, Visual Acuity Exam
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Catherine R. Olinger
Anesthesia
Anesthesia of Endolaryngeal Laser Surgery and Perioperative Side Effects
Investigators analyze the anesthesia of the endolaryngeal laser surgery in patients with smoking with or without monitoring of depth of anesthesia (bispectral index)
- Trial name
- NCT04903483
- Testing
- bispectral index monitoring
- Where
- 2 sites in Hungary
- Volunteers
- 50 people
- Sponsor
- University of Pecs
Postoperative Delirium
Machine Learning Algorithm for Predicting Postoperative Delirium in Elderly Patients After Thoracic Surgery
Postoperative delirium (POD) is a common and severe complication in patients undergoing major surgery, especially in the elderly.
- Trial name
- POD (NCT06226480)
- Where
- China
- Volunteers
- 3,967 people
- Sponsor
- Affiliated Hospital of Nantong University
Post Operative Delirium
Dexmedetomidine Dosage for Postoperative Delirium and Cognitive Function in Elderly TKA Patients
This study aims to evaluate the efficacy of dexmedetomidine in reducing the incidence of postoperative delirium and cognitive dysfunction in elderly patients undergoing total knee arthroplasty (TKA).
- Trial name
- NCT06614881
- Testing
- Dexmedetomidine Injection [Precedex], Dexmedetomidine in 0.9 % NaCl 1,000 Mcg/250 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML), Normal saline
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Tanta University
Delirium
Efficacy and Safety of Suvorexant (MK-4305) for Reducing Incidence of Delirium in Japanese Participants at High Risk of Delirium (MK-4305-085)
The goal of this study is to evaluate the efficacy and safety of suvorexant (MK-4305) for reducing the incidence of delirium in Japanese participants who are at high risk of delirium.
- Trial name
- NCT04571944
- Testing
- Suvorexant
- Where
- 50 sites in Japan
- Volunteers
- 207 people
- Sponsor
- Merck Sharp & Dohme LLC
Delirium - Postoperative
Can Neutrophil-to-Lymphocyte Ratio, Platelet Volume and Platelet Distribution Width Be Used as Indicators of Delirium?
Postoperative delirium is a frequent complication in children undergoing general anesthesia. It has been suggested that inflammation and oxidative stress contribute to the pathophysiology of delirium.
- Trial name
- NCT06701643
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- Ankara City Hospital Bilkent