Clinical trials: Delirium, completed
Emergence Delirium
Incidence of Emergence Delirium in the PACU
Emergence delirium (ED) is serious complication in the postoperative period in paediatric anaesthesia, reported incidence is 20-60%.
- Trial name
- PACUDEL (NCT04531020)
- Testing
- PAED measurement
- Where
- Czechia
- Volunteers
- 1,421 people
- Sponsor
- Brno University Hospital
Delirium
Early Diagnosis and Treatment Standardization of Delirium
1. Observe the characteristics of delirium patients, searching for early diagnostic methods or finding risk factors 2. Design a guideline for delirium, diagnosis or treatment
- Trial name
- NCT03199859
- Where
- South Korea
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Critical Illness, Sedation Complication
Sedation, ANalgesia and Delirium MANagement in Intensive Care Unit
Patients with acute severe health problems often need to be admitted to specialised hospital wards called Intensive Care Units (ICUs) where they can receive emergency treatment such as mechanical ventilation to support their…
- Conditions
- Critical Illness, Sedation Complication, Intensive Care Unit Delirium, Analgesia
- Trial name
- SAnDMAN (NCT05027217)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 3,421 people
- Sponsor
- University of Oxford
Behavior Problem
Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children
The goal of this clinical trial is to learn the effect of dexmedetomidine premedication in postoperative negative behavior changes in children compared to midazolam premedication.
- Trial name
- NCT06417125
- Testing
- Dexmedetomidine Hydrochloride, Midazolam, normal Saline
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Fujian Provincial Hospital
Nurse's Role
Patient-related Effects of Primary Nursing
After a one-year phase of development, primary nursing (process-responsible nursing; PP) has been practically implemented on a pilot ICU since January 2022 at the Heart and Diabetes Center NRW.
- Trial name
- ENGAGE (NCT05569317)
- Testing
- primary nursing
- Where
- Germany
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Delirium, Pain
Evaluation of Quality Indicators on Analgesia, Sedation and Delirium in Intensive Care Patients and Their Impact on Outcome Indicators and Economic Indicators
Retrospective cohort study to investigate the adherence to the process indicators for pain management, sedation management and management of delirium on outcome indicators and cost/revenues in individual patients and subcohorts.
- Trial name
- NCT05384613
- Where
- Germany
- Volunteers
- 20,220 people
- Sponsor
- Charite University, Berlin, Germany
Agitation, Emergence
Intramuscular Ketamine Effect on Postnasal Surgery Agitation
Emergence agitation (EA) is a common complication after nasal surgery. In this study, we aimed to investigate the effect of intramuscular ketamine on EA following septoplasty and open septorhinoplasty (OSRP) when administered at…
- Trial name
- NCT05313659
- Testing
- Ketamine Hydrochloride
- Where
- Jordan
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Jordanian Royal Medical Services
Dementia, Delirium
The Use of PARO to Decrease Agitation in Persons With Dementia and/or Delirium
This Clinical trial tests the efficacy of using the PARO robotic seal to decrease agitation in hospitalized older adults with dementia and/or delirium.
- Trial name
- PARO (NCT05565703)
- Testing
- PARO Robotic Seal Intervention, Attention Control
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Pennsylvania
Anesthesia, General
Recorded Maternal Voice on the Emergence of General Anesthesia on Pediatric Patients
Mother spend a large amount of time with their children. It is assumed that mother contributes to their neurological development not only with visual stimuli, but also with auditory stimuli.
- Trial name
- Maternal voice (NCT02955680)
- Testing
- recorded maternal voice, recorded stranger's voice
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Daegu Catholic University Medical Center
Pregabalin, Dexmedetomidine
Pregabalin Versus Dexmedetomidine for Delirium Prevention After Cardiac Surgery
The aim of this study is to compare the effect of perioperative administration of pregabalin versus dexmedetomidine on the prevalence and lasting duration of delirium in elderly patients after cardiac surgery.
- Conditions
- Pregabalin, Dexmedetomidine, Delirium
- Trial name
- NCT05640479
- Testing
- Pregabalin, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Pain Management, Pediatric Intensive Care Unit
Eye Masks and Earplugs for Delirium and Pain Prevention in Pediatric Intensive Care Unit
This randomized controlled clinical trial aims to evaluate the effect of nighttime application of eye masks and earplugs on the incidence of delirium and pain levels in pediatric intensive care unit (PICU) patients aged 6-12…
- Conditions
- Pain Management, Pediatric Intensive Care Unit, Non-Pharmacological Interventions, Critical Care Nursing
- Trial name
- PICU (NCT06867523)
- Testing
- Eye Mask, Earplugs
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Bozok University
Postoperative Delirium, Postoperative Stroke
Postoperative Stroke and Epiaortic Ultrasound in CABG
This study aims to investigate the incidence of postoperative stroke and neurocognitive impairment in patients undergoing coronary artery bypass grafting (CABG), with or without the use of epi-aortic ultrasound (EAU).
- Trial name
- EAU and POCD (NCT07101393)
- Testing
- Intraoperative Epiaortic Ultrasound (EAU)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ataturk University
Delirium, Cognitive Decline
Early Cognitive Intervention in Delirium
This is a randomized control trial to determine if early cognitive training and rehabilitation improve 4-month cognition in hospitalized older (>=65 years old) delirious patients with and without Alzheimer's disease and related…
- Conditions
- Delirium, Cognitive Decline, Dementia
- Trial name
- ECID (NCT04740567)
- Testing
- Cognitive Training, Goal Management Training
- Where
- 2 sites in United States
- Volunteers
- 283 people
- Sponsor
- Vanderbilt University Medical Center
Delirium
Rate of Postoperative Delirium and Postoperative Cognitive Dysfunction After Spinal Anesthesia
The aim of this investigation is to compare the standard of general anesthesia used in these patients with these short-acting local anesthetics (Chloroprocain (Ampres®) and Prilocain (Takipril®)) for spinal anesthesia as well as…
- Trial name
- NCT03715244
- Testing
- Spinal anesthesia with short-acting local anesthetics, General anesthesia (current standard)
- Where
- Germany
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Postoperative Delirium
Association of Plasma Melatonin Levels With Delirium
Delirium is common complications in postoperative critically ill patients. However the mechanism of postoperative delirium is not well understood.The investigators designed a prospective observational study to investigate the…
- Trial name
- NCT01570881
- Where
- Japan
- Volunteers
- 33 people
- Sponsor
- Okayama University
Postoperative Delirium
Incidence, Long- Term Outcome and Factor Related to Non- Cardiac Postoperative Delirium in Elderly Patients
The purpose of this study is to determine the incidence, long term outcome and factor related to postoperative delirium in elderly patients after non-cardiac surgery.
- Trial name
- POD-I (NCT02131181)
- Where
- Thailand
- Volunteers
- 400 people
- Sponsor
- Chiang Mai University
Strabismus
The Effect of Dexmedetomidine on Decreasing Emergence Agitation and Delirium in Pediatric Patients Undergoing Strabismus Surgery
Postoperative agitation in children is a well-documented clinical phenomenon with incidence ranging from 10% to 67%. Recently, dexmedetomidine has been investigated extensively in the pediatric population and there is now…
- Trial name
- NCT01512355
- Testing
- Dexmedetomidine
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Yonsei University
Delirium, Critical Illness
Delirium Screening 3 Methods Study
Observational study comparing three different methods of delirium detection in critically ill patients.
- Trial name
- DELIS-3 (NCT04551508)
- Where
- 14 sites in Denmark
- Volunteers
- 1,126 people
- Sponsor
- Hospitalsenheden Vest
Agitation, Delirium
Dexmedetomidine to Prevent Agitation After Free Flap Surgery
Reconstruction using microvascular free tissue flap has been an important management in patients with maxillofacial tumor. It is often characterised as long operation time, more traumatic and require restriction of patient's head…
- Trial name
- NCT01904760
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University
Delirium, Hip Fractures
Prevention of Delirium Among Elderly Patients With Hip Fractures
Objective: To evaluate the effect of care bundle on prevention of delirium among elderly patients with hip fractures. Methods: A prospective randomized case control study was performed for 80 patients (≥65 years) with hip…
- Trial name
- NCT03470662
- Testing
- Care bundle
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhoupu Hospital, Pudong New Area, Shanghai, China