Clinical trials: Delirium, completed
Delirium
Perioperative Cognitive Protection - Cognitive Exercise and Cognitive Reserve (The Neurobics Trial)
Many individuals experience an acute change in thinking and reasoning skills after surgery. This is called post-operative delirium (PD). PD symptoms typically start 1-3 days after surgery.
- Trial name
- NCT02230605
- Testing
- Mini-Mental State Examination, Self-Administered Gerocognitive Examination, Geriatric Depression Scale
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Delirium
INCIDENCE OF Delirium After Cardiac SURGERY Surgery
Delirium is a common problem that occurs after cardiac surgery. The incidence of delirium after cardiac surgery is estimated to be 26-52%, with a significant percentage being hypoactive delirium1-4.Postoperative delirium has been…
- Trial name
- NCT04986488
- Where
- Nepal
- Volunteers
- 234 people
- Sponsor
- Shahid Gangalal National Heart Centre
Anxiety State, Child Behavior
The Effect of Child Choice With Accompanying Parent on Postoperative Delirium During Induction of Anesthesia
Induction of anesthesia can be distressing both for children and their parents. Nonpharmacological behavioral interventions can reduce the anxiety of children without significant adverse effects as seen with sedative drugs.
- Conditions
- Anxiety State, Child Behavior, Postoperative Delirium
- Trial name
- NCT05931770
- Testing
- Selection of parent(mother or father) according to children preference, Parent (mother or father) selection according to parents' preference
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Anesthesia, General
Impact of Flumazenil on the Emergence Delirium
Flumazenil rapidly antagonizes benzodiazepines (BZDs); it may induce agitation, seizure, or delirium, especially when applied to patients who have taken BZDs for a long time.
- Trial name
- NCT05681377
- Testing
- Flumazenil
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Korea University Guro Hospital
Old Age, Hip Fractures
Validity and Reliability of the Modified Delirium Diagnostic Tool - Provisional (DDT-Pro) (Thai Version) in Peri-operative Fragility Hip Fracture Patient
Nowadays, the number of hip fracture patients is increasing. As Thailand enters into an aging society, hip fractures are becoming more common. They are typically treated with surgery.
- Conditions
- Old Age, Hip Fractures, Delirium
- Trial name
- NCT06504251
- Testing
- Delirium Diagnostic Tool-Provisional ( DDT-Pro )
- Where
- Thailand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Specified Sedative, Hypnotic
Dyphenhidramine Effect on Prevention of Sevoflurane Induced Post Anesthesia Agitation in Pediatric
The purpose of this study is to investigate the effect of diphenhydramine on the prevention of sevoflurane induced emergence delirium/ agitation in pediatrics.
- Trial name
- NCT02463929
- Testing
- Diphenhydramine, normal saline, Ketamine
- Volunteers
- 50 people
- Sponsor
- Universitas Diponegoro
Sleep Disturbance, Delirium
Therapeutic Touch on Pain, Delirium, Sleep, and Physiological Parameters
The study was conducted to determine the effects of therapeutic touch applied to intensive care patients on pain, delirium, sleep and physiological parameters.
- Trial name
- NCT07404904
- Testing
- therapeutic touch
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sibel Oksuz
Delirium, Sleep Perception
Effect of Daily Interruption of Continuous Sedation on Delirium, Sleep Perception in Intensive Care Unit (ICU) Patients
This is an intervention study whose purpose is to determine whether daily interruption of sedative infusion contributes to the reduction of the occurrence of delirium and improves sleep perception in critically ill patients.
- Trial name
- ICUDelirium (NCT00714194)
- Testing
- Normal continuous sedation, Daily interruption of continuous sedation
- Where
- Puerto Rico
- Volunteers
- 52 people
- Sponsor
- University of California, San Francisco
Postoperative Complications, Delirium
Donepezil in the Prevention of Post-Operative Cognitive Decline
The purpose of this study is to evaluate the feasibility of using Donepezil to prevent post-operative cognitive decline (POCD) among individuals aged 65 and older who have a baseline mild cognitive impairment (MCI) and are…
- Trial name
- NCT00182845
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Pfizer
Rebound Pain Impact After Hip Surgery With Nerve Block
Effect of Rebound Pain on Postoperative Intensive Care Delirium in Patients Undergoing Hip Surgery With Peripheral Nerve Block
Postoperative delirium is a significant and commonly encountered complication in patients undergoing hip surgery, particularly among the elderly.
- Trial name
- NCT07295184
- Testing
- Peripheral nerve block applied, Only multimodal analgesia applied
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Konya City Hospital
Postoperative Delirium (POD)
The Effect of Early Postoperative Pain on Postoperative Delirium (POD) in Elderly Patients Undergoing Abdominal Surgery
This research project is an observational cohort study, representing a secondary analysis of multicenter prospective data from China spanning 2020 to 2022.
- Trial name
- NCT06964893
- Where
- China
- Volunteers
- 3,389 people
- Sponsor
- Chinese PLA General Hospital
Critical Illness, COVID-19
Neurocognitive Impairment in Patients With COVID-19
Delirium and acute neurocognitive impairment are increasingly observed in adult and pediatric patients with COVID-19. Prospective clinical studies combining clinical and laboratory examinations including specific biomarkers of…
- Conditions
- Critical Illness, COVID-19, Central Nervous System Injury, Delirium
- Trial name
- NCoV (NCT04359914)
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- University of Rostock
Delirium
Thiamine Administration and Prevalence of Delirium in the Intensive Care Unit: A Before-after Study
Delirium is a very common condition among ICU-admitted patients, and its prevalence is estimated between 30-40%. Delirium is associated with increased morbidity and mortality and future cognitive decline, along with increased…
- Trial name
- NCT04214106
- Testing
- intravenous Thiamine
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Meir Medical Center
Delirium
Environmental Intervention on Delirious Patients
The implementation of environmental intervention program reduced the duration of delirium and length of stay at the ICU in critically-ill surgical patients.
- Trial name
- NCT04042649
- Testing
- environmental intervention
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Asan Medical Center
Delirium
External Validation of Delirium Prediction Models for Intensive Care Patients
Delirium is frequently observed among critically ill patients and is associated with detrimental outcomes. Currently, no evidence-based prevention or treatment exists for delirium, and especially, the inability to identify…
- Trial name
- NCT05084482
- Testing
- Prediction models
- Where
- Denmark
- Volunteers
- 660 people
- Sponsor
- Zealand University Hospital
Postoperative Delirium
The Relationship Between Zonulin and Interleukin-8 Levels and Postoperative Delirium Development
The relationship between zonulin and interleukin-8 levels and postoperative delirium development in patients who had femur fracture surgery under regional anesthesia
- Trial name
- ZolDel (NCT04875182)
- Testing
- Evaluation of Delirium development
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Dr. Gokhan Vural
Postoperative Delirium in Elder Patients After Spine Surgery
Predictors of Postoperative Delirium in Elder Patients After Spine Surgery: Regional Cerebral Oxygen Saturation
Postoperative delirium is an important problem in patients undergoing major surgery. The incidence of delirium was 12.5% in the patients over 70 years old undergoing spine surgery.
- Trial name
- NCT02331953
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Yonsei University
Delirium
The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial
Delirium is a medical term or condition that includes a temporary inability to focus attention and to think clearly. Delirium occurs commonly (10% to 70%) in patients older than 60 undergoing large surgeries.
- Trial name
- PODCAST (NCT01690988)
- Testing
- Ketamine (0.5 mg/kg), Ketamine (1 mg/kg)
- Where
- United States
- Volunteers
- 746 people
- Sponsor
- Washington University School of Medicine
Cognitive Impairment, Emergency Care
Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department
This is an observational study of the pragmatic implementation of an ED screening, outpatient referral, and care coordination process for older ED patients who may have UCID.
- Conditions
- Cognitive Impairment, Emergency Care, Dementia, Delirium
- Trial name
- IMPACT (NCT04846322)
- Testing
- PD4ED 3-step intervention (ED assessment, outpatient assessment, Brain health plan)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Delirium
Use of a Novel Digital Therapeutic Intervention for the Management of Delirium in the Acute Care Environment
Delirium is a condition of fluctuating confusion and agitation that affects as many as 80% of patients in critical care. Hyperactive delirium consumes a significant amount of clinical attention and resources due to the associated…
- Trial name
- NCT04652622
- Testing
- Mindful Garden
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Fraser Health