Clinical trials: Delirium, completed
Emergence Delirium
Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia
Emergence agitation is commonly encountered after receiving inhalation anesthesia. This distressing phenomenon carries risks that are harmful to patients, caregivers and medical personnel.
- Trial name
- NCT06482125
- Testing
- Dexmedetomidine, Sevoflurane
- Where
- Indonesia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Pelita Harapan University
Emergence Agitation
Propofol Versus Dexmedetomidine Effect on Prevention Emergence Agitation
The goal of this clinical trial is to compare Propofol versus Dexmedetomidine in children undergoing squint surgery. The main question it aims to answer is: Which drug is more effective in preventing the appearance of Emergence…
- Trial name
- NCT06312618
- Testing
- Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Delirium, Aortic Valve Stenosis
Assessing the Incidence of Postoperative Delirium Following Aortic Valve Replacement
Our primary aim in this observational study is to identify the incidence of POD in the first five postoperative days by using the 3-minute Diagnostic confusion assessment method (3D-CAM), the derived version for intensive care…
- Trial name
- IPOD-AV (NCT03950440)
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Anesthesia, Postoperative Delirium
STimulation Electronically of Acupoints for Postoperative Delirium in elderlY Patients
Transcutaneous electrical acupoint stimulation (TEAS) was reported to benefit the patients undergoing surgeries by reducing anesthetics consumption and decreasing anesthesia related adverse effects.
- Conditions
- Anesthesia, Postoperative Delirium, Electroencephalogram
- Trial name
- STEADY (NCT06161662)
- Testing
- transcutaneous electrical acupoint stimulation, Control
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Zhihong LU
Delirium, Falls
Prophylactic Environmental Management of Delirium
Delirium is a complex neuropsychiatric syndrome with an acute onset and fluctuating course which is presented in 15 to 20% of patients admitted to general wards.
- Trial name
- MAPDI (NCT01356810)
- Testing
- Environmental Intervention, Standard Care
- Where
- Chile
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Alzheimer's Disease, Dementia
Safety and Efficacy Study of Ladostigil in Mild to Moderate Probable Alzheimer's Disease
For many, Alzheimer's disease is the number one medical issue facing our aging society. It is a late onset neurodegenerative disease, frequently under diagnosed, that impairs memory and cognitive performance.
- Conditions
- Alzheimer's Disease, Dementia, Memory Loss, Cognitive Impairment
- Trial name
- NCT01354691
- Testing
- ladostigil hemitartrate
- Where
- 19 sites in Austria, Croatia and 3 more
- Volunteers
- 200 people
- Sponsor
- Avraham Pharmaceuticals Ltd
Emergence Agitation
Preemptive Intravenous Micro-dose Dexmedetomidine to Prevent Emergence Agitation in Adult Patients Undergoing Septoplasty Surgeries
This prospective randomized controlled study will be conducted to evaluate the effect of preoperative single, micro-dose of dexmedetomidine (0.3μg/kg) on the incidence and severity of EA in adults undergoing Septoplasty surgeries
- Trial name
- NCT07302815
- Testing
- Dexmedetomidine, Saline
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Postoperative Delirium
Validation of the 3D-CAM to Detect Postoperative Delirium
The 3D-CAM is a new 3-minute diagnostic assessment for Confusion Assessment Method-defined Delirium. The primary objective of this study is to translate the 3D-CAM into the German language, as well as to validate its use to…
- Trial name
- NCT02992717
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
Delirium
Interventions for Postoperative Delirium: Biomarker-2 (IPOD-B2)
The IPOD-B2 Study aims to understand the pathogenesis of postoperative delirium in patients undergoing major surgery. The investigators will identify then correlate soluble biomarkers in blood and cerebral spinal fluid with…
- Trial name
- IPOD-B2 (NCT02926417)
- Testing
- High Density-Electroencephalogram
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Delirium, Intensive Care Unit Syndrome
Risk Factors for Delirium in Critically Ill Surgical Patients
Delirium is characterized by changes in mental status, inattension, disorganized thinking, and altered consciousness. Prevalence of delirium in critically ill patients has varied from 20~80% depending on the severity of illness.
- Trial name
- NCT03050021
- Where
- South Korea
- Volunteers
- 251 people
- Sponsor
- Suk-Kyung
Intensive Care Unit Delirium
Gut Microbiome and ICU Delirium Post Cardiac Surgeries
ICU delirium are assessed by clinical nurses twice every day. Delirious patients are matched with patients according to their disease, gender and age range(±3 years). Stool samples for gene sequencing are collected.
- Trial name
- NCT04056338
- Testing
- No intervention
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Emergence Agitation
Effect of Lollipop on Emergence Delirium in Pediatric Patients Undergoing General Anesthesia
This study aims to evaluate the effectiveness of lollipop administration after surgery in reducing emergence agitation in pediatric patients undergoing anesthesia with sevoflurane at RS Ngoerah.
- Trial name
- LOLLIPOP-ED (NCT07571707)
- Testing
- Lollipop
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Udayana University
Delirium - Postoperative
Effect of Dexmedetomidine Dosage on Postoperative Delirium in Geriatric Orthopedic Surgery
This study evaluates the dose-response relationship of Dexmedetomidine (DEX) in reducing the incidence and severity of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) in elderly patients.
- Trial name
- NCT07443085
- Testing
- Dexmedetomidine (Low dose), Dexmedetomidine (High dose), Fentanyl
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Benha University
C.Surgical Procedure; Cardiac, Acute Kidney Injury
Portal Flow Pulsatility as a Risk Factor for Acute Kidney Injury After Cardiac Surgery
The purpose of this study is to evaluate the possible association between portal vein flow pulsatility and acute kidney injury after cardiac surgery.
- Conditions
- C.Surgical Procedure; Cardiac, Acute Kidney Injury, Postoperative Complications, Right-Sided Heart Failure
- Trial name
- PP-AKI (NCT02831907)
- Testing
- Cardiac surgery
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- Montreal Heart Institute
Immobility Syndrome, Fall
Goal-directed Mobilization of Medical Inpatients
Immobilization in general internal medicine inpatients is a major contributor to morbidity and mortality. Goal-directed mobilization (GDM) may improve mobility.
- Conditions
- Immobility Syndrome, Fall, Delirium, Sarcopenia
- Trial name
- GoMob-in (NCT04760392)
- Testing
- Goal-directed mobilization
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Delirium
Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients
The purpose of this chart review study is to determine whether the use of dexmedetomidine, a selective α2-adrenergic receptor agonist with sedative, analgesic, and antinociceptive properties, would be associated with a lower…
- Trial name
- NCT00417664
- Testing
- Dexmedetomidine, Propofol, Midazolam
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Traumatic Brain Injury, Posttraumatic Confusional State
Amantadine for Treatment of Symptoms of the Post-traumatic Confusional State
Patients with traumatic brain injury often experience a period of acute confusion that may include agitation as they recover from their injuries.
- Conditions
- Traumatic Brain Injury, Posttraumatic Confusional State, Delirium
- Trial name
- NCT00693121
- Testing
- Amantadine hydrochloride
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Methodist Rehabilitation Center
Delirium
Use of Near Infrared Spectroscopy (NIRS) as a Biomarker of Delirium in Hospitalized Older Adults Doing Physical Exercise
Delirium is an important cause of morbimortality in older adults admitted to hospital. Multicomponent interventions targeting delirium risk factors, including physical exercise and mobilization, have been shown to reduce delirium…
- Trial name
- NCT05442892
- Testing
- Multicomponent exercise training programme
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Fundacion Miguel Servet
Lower Extremity Problem, Delirium
Intraoperative Sedatives and Postoperative Deilirium
Delirium occurs commonly in elderly patients. Its incidence after orthopedic surgery has been reported to be 5-61%. Delirium is classified into three sub-types: Hypoactive, hyperactive, and mixed.
- Conditions
- Lower Extremity Problem, Delirium, Propofol, Dexmedetomidine
- Trial name
- NCT03251651
- Testing
- Propofol, Dexmedetomidine
- Where
- South Korea
- Volunteers
- 748 people
- Sponsor
- Seoul National University Bundang Hospital
Delirium, Stroke
Impact of Neuromonitoring During Cardiac Procedures
Through a series of sequential analyses, retrospective database exploration looking for linkages and associations between the use of processed electroencephalogram (EEG) and/or cerebral saturation monitoring and patient outcomes…
- Conditions
- Delirium, Stroke, Acute Kidney Injury
- Trial name
- NCT02681731
- Where
- United States
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG