Clinical trials: Delirium, completed
Delirium, Critical Illness
Light and Noise: Objectively Assessing Environmental Risk Factors for Delirium in the ICU
Recognition of delirium as a medical entity with relevance to both morbidity and mortality, especially in critically ill patients, is a relatively recent development.
- Trial name
- LANYARD-ICU (NCT06294158)
- Testing
- Brightness measurement, Sound level measurement
- Where
- Austria
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Delirium, Anesthesia; Adverse Effect
Assessment of Immediate Postoperative Delirium (IPD) in Adult Patients: Incidence and Etiologic Factors
Delirium is considered to be acute failure of central nervous system. It is acute confusional state characterized by decline from baseline mental level, attention deficit and disorganized thinking.
- Trial name
- AIPDAP (NCT03967496)
- Testing
- Types of Anesthesia, Access of Surgery, Comorbidities
- Where
- Oman
- Volunteers
- 402 people
- Sponsor
- Sultan Qaboos University
Delirium
Nursing Assistant Intervention to Prevent Delirium in Nursing Homes
Delirium is an acute confusion that occurs in one third of hospitalized older adults. As compared to those without delirium, hospitalized patients with delirium have longer hospital stays, higher mortality, and increased risk of…
- Trial name
- NCT02994979
- Testing
- Delirium-prevention
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- Jewish Home & Hospital Lifecare System
Cardiac Surgery, Intraoperative Hemodynamic Instability
Impact of Intraoperative Hemodynamic Instability on Outcomes in Cardiac Surgery
Intraoperative hemodynamic instability (IOHI) is a common occurrence during cardiac surgery and is associated with organ hypoperfusion. However, the specific impact of IOHI on composite adverse outcomes remains unclear.
- Conditions
- Cardiac Surgery, Intraoperative Hemodynamic Instability, Postoperative Complication, Acute Kidney Injury
- Trial name
- NCT07324694
- Where
- Turkey (Türkiye)
- Volunteers
- 351 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Emergence Agitation
Comparison of Emergence Agitation Between Sevoflurane and Desflurane Anesthesia After Orthognathic Surgery
Emergence agitation is a major concern in patients undergoing orthognathic surgery. The patients may experience the sense of suffocation during emergence due to nasotracheal intubation and orofacial edema.
- Trial name
- NCT01878656
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Chung-Ang University Hospital
Hip Fractures, Delirium
Post-Operative Delirium in Elderly Surgical Patients
This research is being done to see what effects sedative drugs during surgery have on peoples' thinking processes after they wake up.
- Trial name
- STRIDE (NCT00590707)
- Testing
- Deeper sedation, Moderate sedation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Delirium
Influence of Apelin Levels on Postoperative Cognitive Disorders After Orthopedic Surgery in Elderlies (APOCOGNIT)
No successful strategy is proposed to patients submitted to important surgery to reduce the incidence of postoperative cognitive disorders (POCD) onset.
- Trial name
- APOCOGNIT (NCT02574234)
- Testing
- Determination of apelin and inflammatory cytokines, Assessment of cognitive functions, Liquid sampling cerebrospinal
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Toulouse
Emergence Agitation
Emergence Agitation in Pediatric Strabismus Surgery
This study was performed to assess the effects of continuous remifentanil infusion and single bolus administration of fentanyl on the incidence of emergence agitation in pediatrics undergoing strabismus surgery.
- Trial name
- NCT03807011
- Testing
- fentanyl group, remifentanil group
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Yeungnam University College of Medicine
Depression, Delirium
Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia
This study is geared toward characterizing the recovery of brain activity and cognitive function following treatments of electroconvulsive therapy and ketamine general anesthesia.
- Conditions
- Depression, Delirium, Seizures, Cognitive Disorders
- Trial name
- RCC2 (NCT02761330)
- Testing
- Ketamine, Electroconvulsive Therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine
Postoperative Pain, Acute, Emergence Delirium
Comparing Ketamine and Fentanyl in Pediatric Tonsillectomy: Pain Control and Emergence Delirium Outcomes (KVFPT)
This study is designed to compare the effectiveness of two medications, ketamine and fentanyl, in managing pain and preventing delirium in children aged 3 to 8 years who are undergoing tonsillectomy and adenoidectomy surgery.
- Trial name
- KVFPT (NCT06630364)
- Testing
- ketamine, fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Medipol University
Dementia, Delirium
Memory and Attention Disorders and Malnutrition in Hospital Setting
This is a cross-sectional observational study that investigates the prevalence of memory disorders, attention disorders (suggesting delirium), and malnutrition in hospitalized older adults (aged 70 years or over) in a tertiary…
- Conditions
- Dementia, Delirium, Cognitive Impairment, Malnutrition
- Trial name
- NCT03252054
- Testing
- Screening for memory disorders, attention disorders, and malnutrition
- Volunteers
- 151 people
- Sponsor
- Tampere University Hospital
Delirium - Postoperative
Effect of the Anticholinergic Drug Burden on Postoperative Delirium in Elderly Chinese Patients: A Nested Case-Control Study
This study aims to investigate the association between preoperative anticholinergic drugs burden and postoperative delirium in elderly Chinese patients.
- Trial name
- ADB and POD (NCT06931353)
- Where
- China
- Volunteers
- 10,536 people
- Sponsor
- Hao Li
Emergence Delirium, Emergence Agitation
Postoperative Neurocognitive Dysfunction: Is There Any Place for Emergency Agitation: A Prospective Cohort Trial
Perioperative neurocognitive disorders (PND) have been studying by clinicians, particularly by anesthesiologists, pretty long, however the most inspiring advancements were achieved during the last few decades.
- Conditions
- Emergence Delirium, Emergence Agitation, Postoperative Delirium
- Trial name
- PoD (NCT04820595)
- Testing
- RASS, CAM-ICU
- Where
- 2 sites in Russia
- Volunteers
- 200 people
- Sponsor
- Negovsky Reanimatology Research Institute
Delirium
ICU Delirium: a One-week Snapshot of Burden Across the Eastern UK Region
ICU delirium negatively impacts on patient outcomes, as well as on resources and clinical workflow of the ICU. Effective healthcare resource planning requires reliable (i.e., multicentre) data that can inform on both of these.
- Trial name
- NCT01902277
- Where
- United Kingdom
- Volunteers
- 225 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Delirium, Ischemic Stroke
Post-stroke Delirium Screening
For a long time, delirium was considered a merely temporary dysfunction of the brain. Today, it is established that it is a brain disease associated with network dysfunction, neuroinflammation and impaired transmitter homeostasis…
- Conditions
- Delirium, Ischemic Stroke, Transient Ischemic Attack
- Trial name
- PSD Screen (NCT03930719)
- Testing
- Stroke screening tools
- Where
- Germany
- Volunteers
- 141 people
- Sponsor
- University Medicine Greifswald
Delirium in Old Age, Delirium Superimposed on Dementia
Early Fall Risk Detection and Fall Prevention Among Inpatients With Delirium
During delirium patients are at risk of severe harm due to unattended bed-exits resulting in falls. This research intends to explore how effective alarming contact mats (CareMat®) in comparison to contactless bed-exit alarming…
- Conditions
- Delirium in Old Age, Delirium Superimposed on Dementia, Fall, Bed Falls
- Trial name
- QumPreFall (NCT05391334)
- Testing
- Qumea
- Where
- Switzerland
- Volunteers
- 170 people
- Sponsor
- University Department of Geriatric Medicine FELIX PLATTER
Delirium
Feasibility of a Software App for Testing Inattention in Delirium
This qualitative study aims to evaluate the usability of a smartphone application called DelApp. The study will assess usability and acceptability of the software app by asking 40 clinicians to administer the DelApp assessment to…
- Trial name
- NCT02603380
- Testing
- No intervention
- Volunteers
- 48 people
- Sponsor
- University of Edinburgh
Aortic Valve Replacement, Aortic Stenosis
TAVI Protocol - Paravertebral Block Study
Trans-apical aortic valve replacement is a new treatment for severe aortic stenosis. It is offered to elderly patients with medical problems that would markedly increase the risk of conventional cardiac surgery.
- Trial name
- TAVI PVB (NCT01404975)
- Testing
- Thoracic paravertebral block (PVB)
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Delirium, Anesthesia Emergence, Delirium
The Efficacy of Oral Melatonin in Preventing Postoperative Delirium for Patients Undergoing Orthopedic Surgery Under General Anesthesia
Postoperative delirium is a complication that should not be underestimated. As it elaborates many complications that could be avoided when an accurate assessment of the risk factors and interventional measures are taken…
- Trial name
- NCT05236907
- Testing
- Melatonin, No intervention, Midazolam
- Where
- 2 sites in Iraq
- Volunteers
- 36 people
- Sponsor
- University of Baghdad
Emergence Agitation, Anesthesia Recovery
Bispectral Index, Suppression Rate and Emergence Agitation in Spine Surgeries
Emergence agitation; generally refers to a situation that may occur after a surgical intervention or anesthesia. This situation describes the irritability and agitation of the patient during the recovery process and the period of…
- Conditions
- Emergence Agitation, Anesthesia Recovery, Bispectral Index Monitor
- Trial name
- NCT06334939
- Testing
- Bispectral Index Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Ahmet Yuksek