Clinical trials: Delirium, completed
Anesthesia, Local Anesthesia
Dexmedetomidine vs Propofol Sedation Reduces Postoperative Delirium in Patients Receiving Hip Arthroplasty.
With blocks of lumbar and lumbar plexus, we can reduce the intravenous anesthetics usage. To offer an satisfied surgery process for patients, a proper sedation is necessary.
- Trial name
- NCT02793986
- Testing
- propofol, dexmedetomidine
- Where
- China
- Volunteers
- 296 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Anxiety
Comparison of Usual Care and Distraction (Tablet) in Children 3-5 Years Old
Randomized control trial comparing usual care and distraction (tablet) on anxiety, emergence delirium, sedation/agitation, and vomiting in children 3-5 years old
- Trial name
- NCT05368961
- Testing
- Distraction, Usual care
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Delirium
Nursing Assistant Intervention to Prevent Delirium in Nursing Homes
Delirium is an acute confusion that occurs in one third of hospitalized older adults. As compared to those without delirium, hospitalized patients with delirium have longer hospital stays, higher mortality, and increased risk of…
- Trial name
- NCT02994979
- Testing
- Delirium-prevention
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- Jewish Home & Hospital Lifecare System
Confusion, Delirium
Validation of a French Version of the Confusion Assessment Method (CAM)
To validate the French version of the CAM, a multicenter diagnostic study will be conducted. The principle of this study is identical to the study of Inouye which initially validated the CAM in 1990.
- Trial name
- NCT01775982
- Testing
- Psychiatric evaluation, Geriatric evaluation
- Where
- 8 sites in France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Accidental Falls
The HIP-HOP Flooring Study: Helping Injury Prevention in Hospitalised Older People
In hospitals, older people can fall and hurt themselves. The investigators want to see if a new type of flooring can help stop people hurting themselves as badly, if they accidentally fall.
- Trial name
- NCT00817869
- Testing
- New flooring
- Where
- 8 sites in United Kingdom
- Volunteers
- 571 people
- Sponsor
- University of Portsmouth
Delirium
DElirium prediCtIon in the intenSIve Care Unit: Head to Head comparisON of Two Delirium Prediction Models
Currently, two ICU delirium prediction models are available: the PRE-DELIRIC model and the early prediction model (E-PRE-DELRIC).
- Trial name
- DECISION (NCT02518646)
- Where
- Netherlands
- Volunteers
- 2,500 people
- Sponsor
- Radboud University Medical Center
Postoperative Delirium
Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial
The purpose of this study is to find out whether postoperative delirium can be more properly prevented by the combination of determined preventive agents in past studies.
- Trial name
- PRIDe (NCT02433041)
- Testing
- Haloperidol, Ketamine, Haloperidol + Ketamine
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Delirium
Dexmetomedine for Post Operative Delirium in Elderly Patients Undergoing Elective Total Knee Replacement Under Spinal Anesthesia
Postoperative delirium is a geriatric syndrome occurring after anesthesia and surgery which manifests as acute alterations in mental status, involving changes in cognition, attention, and levels of consciousness that tend to…
- Trial name
- NCT05707741
- Testing
- dexmetomedine infusion
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Emergence Agitation
Sphenopalatine Ganglion Block for Nasal Surery
nasal surgery carries many perioperative challenges, intraoperative bleeing and its effect on surgical field i the main intraoperative concern an postoperative agitation and its serious complications is the main postoperative…
- Trial name
- NCT04168879
- Testing
- Bupivacaine 0.5% Preservative-Free Injectable Solution, normal saline
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Assiut University
Delirium
ICU Delirium: a One-week Snapshot of Burden Across the Eastern UK Region
ICU delirium negatively impacts on patient outcomes, as well as on resources and clinical workflow of the ICU. Effective healthcare resource planning requires reliable (i.e., multicentre) data that can inform on both of these.
- Trial name
- NCT01902277
- Where
- United Kingdom
- Volunteers
- 225 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Remimazolam, Tonsillectomy
Remimazolam for Emergence Delirium Prevention in Children Undergoing Tonsillectomy
The aim of this study is to confirm the effectiveness of remimazolam in preventing delirium during emergence from anesthesia in children who will undergo elective procedures of tonsillectomy, adenotonsillectomy or adenoidectomy…
- Conditions
- Remimazolam, Tonsillectomy, Emergence Delirium
- Trial name
- NCT07704437
- Testing
- Remimazolam 20 MG Injection [Byfavo], NaCl (0,9%)
- Where
- Croatia
- Volunteers
- 110 people
- Sponsor
- University Hospital of Split
Delirium
Melatonin and Sleep in Preventing Delirium in the Hospital
Recent data suggests that melatonin, a supplement available over the counter, may help prevent delirium in hospitalized patients.
- Trial name
- MELO (NCT02597231)
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Scripps Health
Postoperative Delirium
An Observational Study on the Relationship Between Tear Metabolomics and POD
To explore the correlation between tear metabolomics and POD. The purpose of this study was to compare the results of tear metabolomics between POD and non-POD elderly patients undergoing abdominal surgery, to clarify the…
- Trial name
- NCT05548153
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Cardiac Surgical Procedures
Low Dose Dexmedetomidine and Delirium After Cardiac Surgery
Delirium after cardiac surgery can occur in up to 50% of the patients and has been shown to be significantly associated with increased morbidity and mortality. Advanced age is a significant risk factor of delirium.
- Trial name
- LOWDEXDEL (NCT03388541)
- Testing
- Dexmedetomidine
- Where
- Belgium
- Volunteers
- 420 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Colorectal Cancer (MSI-H), Postoperative Delirium (POD)
POD Risk for Colorectal Cancer Surgery
Postoperative delirium is a common complication after colorectal cancer surgery that hinders recovery. This observational study hypothesizes that a simple, practical risk tool can be developed by combining preoperative clinical…
- Trial name
- NCT07597330
- Where
- China
- Volunteers
- 590 people
- Sponsor
- LanZhou University
Delirium
Evaluation of Delirium Prevention in Critically Ill Patients
Haloperidol is prescribed in high risk ICU patients concerning delirium (50% or more chance to develop delirium detected with the delirium prediction model PRE-DELIRIC, or patients with history of dementia or alcohol abuse)since…
- Trial name
- NCT01187667
- Where
- Netherlands
- Volunteers
- 650 people
- Sponsor
- Radboud University Medical Center
Delirium, Elderly Patient
Evaluation of the Efficiency of Neutrophil-Lymphocyte Ratio in Predicting Delirium in Geriatric Patients Undergoing Hip Fracture Surgery
Aim: Postoperative delirium (POD) is one of the most common complications in elderly patients and is associated with increased morbidity, mortality, length of hospital stay and medical care costs.
- Conditions
- Delirium, Elderly Patient, Hip Fracture Surgery, Neutrophil Lymphocyte Ratio
- Trial name
- NCT07741175
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Postoperative Delirium
Predictive Value of β2-microspheres for Postoperative Delirium
This study evaluated the predictive value of β2-microspheres for postoperative delirium (POD) in the elderly after orthopedic surgery.
- Trial name
- NCT03130231
- Where
- China
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Zhongda Hospital
Cancer
The Preventative Role of Exogenous Melatonin Administration in Patients With Advanced Cancer Who Are at Risk of Delirium: a Feasibility Study
The purpose of this feasibility study is to inform a larger randomized, placebo-controlled, double blind, parallel-group, single-centre trial of an oral, daily administered single dose of melatonin to prevent delirium in patients…
- Trial name
- NCT02200172
- Testing
- Melatonin
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Bruyère Health Research Institute.
Strabismus
Anesthetic Depth and the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery
This study evaluates the association between the depth of general anesthesia and the occurrence of emergence agitation (EA). The investigators hypothesized that optimal level of anesthetic depth could decrease the incidence of EA…
- Trial name
- NCT02521259
- Testing
- BIS
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Bundang Hospital